Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 11350
  • Symbol: Abl1
  • Description: c-abl oncogene 1, non-receptor tyrosine kinase

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11350 GO:0000287 IDA enables magnesium ion binding 9109492 Function
11350 GO:0004672 IDA enables protein kinase activity 11864995,12672821 Function
11350 GO:0004672 IMP enables protein kinase activity 24863063 Function
11350 GO:0004713 IDA enables protein tyrosine kinase activity 9109492,11390389,12944467,15657060,18827006,20417104,23100514..... Function
11350 GO:0004713 IGI enables protein tyrosine kinase activity 18827006,20837657 Function
11350 GO:0004713 IMP enables protein tyrosine kinase activity 10825157,12167702,17626041,20823226,20980600,22729085..... Function
11350 GO:0005515 IPI enables protein binding 8861907,10567556,11163214,11494128,15148308,17254966,19470755,..... Function
11350 GO:0005524 IDA enables ATP binding 9109492 Function
11350 GO:0016301 IDA enables kinase activity 12379650 Function
11350 GO:0019904 IPI enables protein domain specific binding 8438166 Function
11350 GO:0030145 IDA enables manganese ion binding 9109492 Function
11350 GO:0038191 IPI enables neuropilin binding 24863063 Function
11350 GO:0046875 IPI enables ephrin receptor binding 24658113 Function
11350 GO:0051015 IDA enables actin filament binding 11864995 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11350 GO:0001843 IGI acts_upstream_of_or_within neural tube closure 9883720 Process
11350 GO:0001922 IMP acts_upstream_of_or_within B-1 B cell homeostasis 19228876 Process
11350 GO:0002322 IGI acts_upstream_of_or_within B cell proliferation involved in immune response 7671324 Process
11350 GO:0002322 IMP acts_upstream_of_or_within B cell proliferation involved in immune response 8806812,11120811 Process
11350 GO:0002333 IMP acts_upstream_of_or_within transitional one stage B cell differentiation 19228876 Process
11350 GO:0006468 IDA involved_in protein phosphorylation 21690296 Process
11350 GO:0006468 IMP involved_in protein phosphorylation 24863063 Process
11350 GO:0006909 IGI acts_upstream_of_or_within phagocytosis 23100514 Process
11350 GO:0006909 IMP acts_upstream_of_or_within phagocytosis 22665498 Process
11350 GO:0006979 IMP acts_upstream_of_or_within response to oxidative stress 17626041 Process
11350 GO:0007173 IGI acts_upstream_of_or_within epidermal growth factor receptor signaling pathway 18827006 Process
11350 GO:0007249 IGI acts_upstream_of I-kappaB kinase/NF-kappaB signaling 18025176 Process
11350 GO:0009791 IGI acts_upstream_of_or_within post-embryonic development 9883720 Process
11350 GO:0018108 IDA acts_upstream_of_or_within peptidyl-tyrosine phosphorylation 20417104 Process
11350 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 9109492,11390389 Process
11350 GO:0021587 IGI acts_upstream_of_or_within cerebellum morphogenesis 20980600 Process
11350 GO:0022408 IGI acts_upstream_of_or_within negative regulation of cell-cell adhesion 24367707 Process
11350 GO:0030035 IDA acts_upstream_of_or_within microspike assembly 11864995 Process
11350 GO:0030036 IDA involved_in actin cytoskeleton organization 11279004 Process
11350 GO:0030182 IGI acts_upstream_of_or_within neuron differentiation 9883720 Process
11350 GO:0030509 IMP acts_upstream_of BMP signaling pathway 22729085 Process
11350 GO:0030514 IMP acts_upstream_of_or_within negative regulation of BMP signaling pathway 22729085 Process
11350 GO:0032609 IGI acts_upstream_of type II interferon production 18025176 Process
11350 GO:0032623 IGI acts_upstream_of interleukin-2 production 18025176 Process
11350 GO:0032729 IGI acts_upstream_of_or_within positive regulation of type II interferon production 18025176 Process
11350 GO:0032743 IGI acts_upstream_of_or_within positive regulation of interleukin-2 production 18025176 Process
11350 GO:0032956 IGI acts_upstream_of_or_within regulation of actin cytoskeleton organization 9883720,20980600 Process
11350 GO:0033690 IMP acts_upstream_of_or_within positive regulation of osteoblast proliferation 22729085 Process
11350 GO:0034446 IDA acts_upstream_of_or_within substrate adhesion-dependent cell spreading 11864995 Process
11350 GO:0042100 IMP acts_upstream_of_or_within B cell proliferation 19228876 Process
11350 GO:0042127 IGI acts_upstream_of_or_within regulation of cell population proliferation 10805805 Process
11350 GO:0043065 IMP acts_upstream_of_or_within positive regulation of apoptotic process 19805123 Process
11350 GO:0043123 IGI acts_upstream_of_or_within positive regulation of I-kappaB kinase/NF-kappaB signaling 18025176 Process
11350 GO:0043124 IMP acts_upstream_of_or_within negative regulation of I-kappaB kinase/NF-kappaB signaling 19805123 Process
11350 GO:0043525 IMP acts_upstream_of_or_within positive regulation of neuron apoptotic process 20823226 Process
11350 GO:0045580 IMP involved_in regulation of T cell differentiation 21690296 Process
11350 GO:0045930 IDA acts_upstream_of_or_within negative regulation of mitotic cell cycle 8612582 Process
11350 GO:0045930 IGI acts_upstream_of_or_within negative regulation of mitotic cell cycle 8612582 Process
11350 GO:0045931 IGI acts_upstream_of_or_within positive regulation of mitotic cell cycle 18827006 Process
11350 GO:0046632 IGI acts_upstream_of_or_within alpha-beta T cell differentiation 18025176 Process
11350 GO:0048008 IDA acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway 20417104 Process
11350 GO:0048008 IMP acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway 18827006 Process
11350 GO:0048536 IMP acts_upstream_of_or_within spleen development 2065352 Process
11350 GO:0048538 IMP acts_upstream_of_or_within thymus development 2065352 Process
11350 GO:0050798 IMP acts_upstream_of_or_within activated T cell proliferation 18025176 Process
11350 GO:0050852 IDA acts_upstream_of_or_within T cell receptor signaling pathway 18305217 Process
11350 GO:0050853 IMP acts_upstream_of_or_within B cell receptor signaling pathway 11120811,19228876 Process
11350 GO:0050885 IGI acts_upstream_of_or_within neuromuscular process controlling balance 20980600 Process
11350 GO:0051281 IGI acts_upstream_of_or_within positive regulation of release of sequestered calcium ion into cytosol 19228876 Process
11350 GO:0051402 IMP acts_upstream_of neuron apoptotic process 20823226 Process
11350 GO:0051649 IGI acts_upstream_of_or_within establishment of localization in cell 23100514 Process
11350 GO:0051649 IMP acts_upstream_of_or_within establishment of localization in cell 22665498 Process
11350 GO:0051726 IDA acts_upstream_of_or_within regulation of cell cycle 11809706 Process
11350 GO:0060020 IGI acts_upstream_of_or_within Bergmann glial cell differentiation 20980600 Process
11350 GO:0060563 IGI acts_upstream_of_or_within neuroepithelial cell differentiation 9883720 Process
11350 GO:0070371 IMP acts_upstream_of ERK1 and ERK2 cascade 22729085 Process
11350 GO:0070373 IMP acts_upstream_of_or_within negative regulation of ERK1 and ERK2 cascade 22729085 Process
11350 GO:0070374 IMP acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade 18827006 Process
11350 GO:0071222 IMP acts_upstream_of_or_within cellular response to lipopolysaccharide 8806812 Process
11350 GO:0072359 IGI acts_upstream_of_or_within circulatory system development 9883720 Process
11350 GO:0090050 IDA involved_in positive regulation of cell migration involved in sprouting angiogenesis 24863063 Process
11350 GO:0090398 IGI acts_upstream_of cellular senescence 22729085 Process
11350 GO:0098609 IGI acts_upstream_of cell-cell adhesion 24367707 Process
11350 GO:1900272 IGI involved_in negative regulation of long-term synaptic potentiation 24658113 Process
11350 GO:1903053 IGI acts_upstream_of_or_within regulation of extracellular matrix organization 20980600 Process
11350 GO:1903905 IMP involved_in positive regulation of establishment of T cell polarity 22810897 Process
11350 GO:1904157 IGI acts_upstream_of_or_within DN4 thymocyte differentiation 18025176 Process
11350 GO:1905244 IGI involved_in regulation of modification of synaptic structure 24658113 Process
11350 GO:1905555 IMP involved_in positive regulation of blood vessel branching 24863063 Process
11350 GO:2000096 IGI acts_upstream_of_or_within positive regulation of Wnt signaling pathway, planar cell polarity pathway 20837657 Process
11350 GO:2000352 IGI acts_upstream_of_or_within negative regulation of endothelial cell apoptotic process 23840065 Process
11350 GO:2000406 IMP involved_in positive regulation of T cell migration 22810897 Process
11350 GO:2000772 IGI acts_upstream_of_or_within regulation of cellular senescence 22729085 Process
11350 GO:2000773 IGI acts_upstream_of_or_within negative regulation of cellular senescence 22729085 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11350 GO:0005634 IDA located_in nucleus 8612582,9636171 Component
11350 GO:0005737 IDA located_in cytoplasm 9636171,11864995 Component
11350 GO:0015629 IDA located_in actin cytoskeleton 11864995 Component
11350 GO:0031252 IDA located_in cell leading edge 20417104 Component