Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 11651
  • Symbol: Akt1
  • Description: thymoma viral proto-oncogene 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11651 GO:0001649 IGI acts_upstream_of_or_within osteoblast differentiation 19208758 Process
11651 GO:0001893 IMP acts_upstream_of_or_within maternal placenta development 12783884 Process
11651 GO:0005977 IMP acts_upstream_of_or_within glycogen metabolic process 12783884 Process
11651 GO:0006006 IMP acts_upstream_of_or_within glucose metabolic process 19897600 Process
11651 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 12145204,14730361,15192701,15937334 Process
11651 GO:0006468 IDA involved_in protein phosphorylation 20333297,31915252 Process
11651 GO:0006954 IDA acts_upstream_of_or_within inflammatory response 14730361 Process
11651 GO:0006954 IGI involved_in inflammatory response 31874168 Process
11651 GO:0007281 IDA acts_upstream_of_or_within germ cell development 12140361 Process
11651 GO:0008286 IDA involved_in insulin receptor signaling pathway 20889126 Process
11651 GO:0008286 IMP involved_in insulin receptor signaling pathway 9415393,11282895 Process
11651 GO:0008637 IDA acts_upstream_of_or_within apoptotic mitochondrial changes 12869584 Process
11651 GO:0009408 IGI involved_in response to heat 31874168 Process
11651 GO:0009725 IDA involved_in response to hormone 16357133 Process
11651 GO:0010033 IDA acts_upstream_of_or_within response to organic substance 17475835 Process
11651 GO:0010467 IMP acts_upstream_of_or_within_positive_effect gene expression 31272455 Process
11651 GO:0010628 IMP involved_in positive regulation of gene expression 18292230 Process
11651 GO:0010629 IDA involved_in negative regulation of gene expression 19933931 Process
11651 GO:0010763 IMP acts_upstream_of_or_within positive regulation of fibroblast migration 23871832 Process
11651 GO:0010765 IDA acts_upstream_of_or_within positive regulation of sodium ion transport 17715136 Process
11651 GO:0010765 IMP acts_upstream_of_or_within positive regulation of sodium ion transport 17715136 Process
11651 GO:0010975 IDA acts_upstream_of_or_within regulation of neuron projection development 21976490 Process
11651 GO:0010975 IDA involved_in regulation of neuron projection development 19778506 Process
11651 GO:0016567 IDA acts_upstream_of_or_within protein ubiquitination 12145204 Process
11651 GO:0018105 IDA acts_upstream_of_or_within peptidyl-serine phosphorylation 16513828 Process
11651 GO:0018105 IMP involved_in peptidyl-serine phosphorylation 10983986 Process
11651 GO:0022605 IMP acts_upstream_of_or_within mammalian oogenesis stage 34635817 Process
11651 GO:0030163 IDA acts_upstream_of_or_within protein catabolic process 12145204 Process
11651 GO:0031641 IMP acts_upstream_of_or_within regulation of myelination 24101522 Process
11651 GO:0031663 IDA acts_upstream_of_or_within lipopolysaccharide-mediated signaling pathway 24740015 Process
11651 GO:0032094 IDA acts_upstream_of_or_within response to food 16513828 Process
11651 GO:0032287 IMP acts_upstream_of_or_within peripheral nervous system myelin maintenance 20448149 Process
11651 GO:0032436 IMP acts_upstream_of_or_within positive regulation of proteasomal ubiquitin-dependent protein catabolic process 15937334 Process
11651 GO:0032869 IDA acts_upstream_of_or_within cellular response to insulin stimulus 17715136 Process
11651 GO:0032869 IDA involved_in cellular response to insulin stimulus 19139280 Process
11651 GO:0032869 IMP acts_upstream_of_or_within cellular response to insulin stimulus 17715136 Process
11651 GO:0032880 IDA acts_upstream_of_or_within regulation of protein localization 17715136 Process
11651 GO:0032880 IMP involved_in regulation of protein localization 9415393 Process
11651 GO:0035924 IDA acts_upstream_of_or_within cellular response to vascular endothelial growth factor stimulus 25139353 Process
11651 GO:0036294 IDA acts_upstream_of_or_within cellular response to decreased oxygen levels 24875179 Process
11651 GO:0042593 IMP acts_upstream_of_or_within glucose homeostasis 19897600 Process
11651 GO:0042640 IMP acts_upstream_of_or_within anagen 15713628 Process
11651 GO:0042981 IDA involved_in regulation of apoptotic process 18977203 Process
11651 GO:0043066 IMP involved_in negative regulation of apoptotic process 11282895 Process
11651 GO:0043154 IDA involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 18977203 Process
11651 GO:0043161 IMP acts_upstream_of proteasome-mediated ubiquitin-dependent protein catabolic process 15937334 Process
11651 GO:0043491 IGI acts_upstream_of_or_within protein kinase B signaling 15249583 Process
11651 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 18762576 Process
11651 GO:0046622 IMP acts_upstream_of_or_within positive regulation of organ growth 15713641 Process
11651 GO:0048009 IDA involved_in insulin-like growth factor receptor signaling pathway 11784871 Process
11651 GO:0048009 IGI involved_in insulin-like growth factor receptor signaling pathway 32439763 Process
11651 GO:0048266 IGI involved_in behavioral response to pain 31874168 Process
11651 GO:0051146 IGI acts_upstream_of_or_within striated muscle cell differentiation 18762576 Process
11651 GO:0060709 IMP acts_upstream_of_or_within glycogen cell differentiation involved in embryonic placenta development 12783884 Process
11651 GO:0060716 IMP acts_upstream_of_or_within labyrinthine layer blood vessel development 12783884 Process
11651 GO:0071356 IDA acts_upstream_of_or_within cellular response to tumor necrosis factor 24349514 Process
11651 GO:0071363 IDA acts_upstream_of_or_within cellular response to growth factor stimulus 19744960 Process
11651 GO:0071364 IDA involved_in cellular response to epidermal growth factor stimulus 21712384 Process
11651 GO:0071380 IDA acts_upstream_of_or_within cellular response to prostaglandin E stimulus 23479225 Process
11651 GO:0090201 IDA involved_in negative regulation of release of cytochrome c from mitochondria 18977203 Process
11651 GO:0097011 IDA acts_upstream_of_or_within cellular response to granulocyte macrophage colony-stimulating factor stimulus 23610142 Process
11651 GO:0097194 IDA acts_upstream_of_or_within execution phase of apoptosis 12124386 Process
11651 GO:0099175 IDA involved_in regulation of postsynapse organization 26844834 Process
11651 GO:0099175 IMP involved_in regulation of postsynapse organization 26844834 Process
11651 GO:1901653 IDA acts_upstream_of_or_within cellular response to peptide 23793062 Process
11651 GO:2000010 IMP involved_in positive regulation of protein localization to cell surface 9415393 Process
11651 GO:2001243 IMP involved_in negative regulation of intrinsic apoptotic signaling pathway 19911006 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11651 GO:0004672 IDA enables protein kinase activity 14730361,15010863,15192701,16357133,31915252 Function
11651 GO:0004674 EXP enables protein serine/threonine kinase activity 10454575 Function
11651 GO:0004674 IDA enables protein serine/threonine kinase activity 22057101,23495099 Function
11651 GO:0004674 IMP enables protein serine/threonine kinase activity 10983986 Function
11651 GO:0005515 IPI enables protein binding 12791994,15722337,15753085,16051150,16116448,16357133,16792529..... Function
11651 GO:0016301 IDA enables kinase activity 23886629 Function
11651 GO:0019901 IPI enables protein kinase binding 22057101 Function
11651 GO:0106310 IDA enables protein serine kinase activity 11784871 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11651 GO:0005634 IDA located_in nucleus 18388859,20333297,23786676 Component
11651 GO:0005737 IDA located_in cytoplasm 12124386,18388859,19596798,23786676 Component
11651 GO:0005739 IDA located_in mitochondrion 16116448 Component
11651 GO:0005819 IDA located_in spindle 15509711 Component
11651 GO:0005829 IDA located_in cytosol 28930673 Component
11651 GO:0005886 IDA located_in plasma membrane 15775979,20333297,22750946,25217619,31915252 Component
11651 GO:0005911 IDA located_in cell-cell junction 23793062 Component
11651 GO:0036064 IDA located_in ciliary basal body 19596798 Component
11651 GO:0098978 IDA is_active_in glutamatergic synapse 26844834 Component
11651 GO:0098978 IMP is_active_in glutamatergic synapse 26844834 Component