Gene Ontology

Gene Info

• Species: Rat (Rattus norvegicus)
• GeneID: 117279
• Symbol: Cflar
• Description: CASP8 and FADD-like apoptosis regulator

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
117279	GO:0001666	IEP	involved_in	response to hypoxia	23926673	Process
117279	GO:0010667	IMP	involved_in	negative regulation of cardiac muscle cell apoptotic process	14596792	Process
117279	GO:0010976	IMP	involved_in	positive regulation of neuron projection development	20427667	Process
117279	GO:0032869	IEP	involved_in	cellular response to insulin stimulus	18292530	Process
117279	GO:0033574	IDA	involved_in	response to testosterone	12811833	Process
117279	GO:0043066	IMP	involved_in	negative regulation of apoptotic process	12135878	Process
117279	GO:0070374	IMP	involved_in	positive regulation of ERK1 and ERK2 cascade	23412386	Process
117279	GO:0071364	IEP	involved_in	cellular response to epidermal growth factor stimulus	16033771	Process
117279	GO:0071392	IEP	involved_in	cellular response to estradiol stimulus	26566102	Process
117279	GO:0071456	IEP	involved_in	cellular response to hypoxia	12031707	Process
117279	GO:0071549	IEP	involved_in	cellular response to dexamethasone stimulus	16167066	Process
117279	GO:0071732	IMP	involved_in	cellular response to nitric oxide	18292530	Process
117279	GO:0072126	IMP	involved_in	positive regulation of glomerular mesangial cell proliferation	24691542	Process
117279	GO:1903055	IMP	involved_in	positive regulation of extracellular matrix organization	24691542	Process
117279	GO:1903427	IMP	involved_in	negative regulation of reactive oxygen species biosynthetic process	18292530	Process
117279	GO:1903845	IMP	involved_in	negative regulation of cellular response to transforming growth factor beta stimulus	18314484	Process
117279	GO:1903944	IMP	involved_in	negative regulation of hepatocyte apoptotic process	16167066	Process
117279	GO:1904036	IDA	involved_in	negative regulation of epithelial cell apoptotic process	18314484	Process
117279	GO:2000347	IMP	involved_in	positive regulation of hepatocyte proliferation	16033771	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
117279	GO:0002020	IPI	enables	protease binding	17518537	Function
117279	GO:0005123	IPI	enables	death receptor binding	17518537	Function
117279	GO:0044877	IPI	enables	protein-containing complex binding	17518537	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
117279	GO:0031264	IDA	part_of	death-inducing signaling complex	17518537	Component
117279	GO:0031265	IDA	part_of	CD95 death-inducing signaling complex	16493077	Component