Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 12288
  • Symbol: Cacna1c
  • Description: calcium channel, voltage-dependent, L type, alpha 1C subunit

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12288 GO:0002095 IDA part_of caveolar macromolecular signaling complex 16648270 Component
12288 GO:0005886 IDA located_in plasma membrane 7598723,15090038 Component
12288 GO:0005891 IMP part_of voltage-gated calcium channel complex 3315915,12881419 Component
12288 GO:0016020 IDA located_in membrane 15132976 Component
12288 GO:0030018 IDA located_in Z disc 19383796 Component
12288 GO:0030315 IDA located_in T-tubule 22355118 Component
12288 GO:0043025 IDA located_in neuronal cell body 15090038 Component
12288 GO:0043198 IDA located_in dendritic shaft 15090038 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12288 GO:0005245 IDA enables voltage-gated calcium channel activity 1385406,7635187,16267232 Function
12288 GO:0005245 IMP enables voltage-gated calcium channel activity 12881419,14609949,15504730,16251435 Function
12288 GO:0005515 IPI enables protein binding 16352659,16648270,16787652,20639889,24952909 Function
12288 GO:0019899 IPI enables enzyme binding 21670503 Function
12288 GO:0086007 IDA enables voltage-gated calcium channel activity involved in cardiac muscle cell action potential 32109384 Function
12288 GO:1905030 IMP enables voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 18045623 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12288 GO:0006816 IDA acts_upstream_of_or_within calcium ion transport 7635187 Process
12288 GO:0006816 IMP acts_upstream_of_or_within calcium ion transport 15132976,16251435 Process
12288 GO:0006874 IMP acts_upstream_of_or_within intracellular calcium ion homeostasis 15132976 Process
12288 GO:0006939 IMP acts_upstream_of_or_within smooth muscle contraction 16636102 Process
12288 GO:0007268 IMP acts_upstream_of_or_within chemical synaptic transmission 16251435 Process
12288 GO:0007628 IGI acts_upstream_of_or_within adult walking behavior 9882694 Process
12288 GO:0008217 IMP acts_upstream_of_or_within regulation of blood pressure 14609949 Process
12288 GO:0008542 IMP acts_upstream_of_or_within visual learning 16251435 Process
12288 GO:0017156 IMP acts_upstream_of_or_within calcium-ion regulated exocytosis 12881419 Process
12288 GO:0019229 IMP acts_upstream_of_or_within regulation of vasoconstriction 14609949 Process
12288 GO:0030073 IMP acts_upstream_of_or_within insulin secretion 12881419 Process
12288 GO:0030252 IDA acts_upstream_of_or_within growth hormone secretion 1385406 Process
12288 GO:0042593 IMP acts_upstream_of_or_within glucose homeostasis 12881419 Process
12288 GO:0045762 IDA involved_in positive regulation of adenylate cyclase activity 24086669 Process
12288 GO:0046620 IMP acts_upstream_of_or_within regulation of organ growth 15132976 Process
12288 GO:0051649 IDA acts_upstream_of_or_within establishment of localization in cell 32109384 Process
12288 GO:0051649 IMP acts_upstream_of_or_within establishment of localization in cell 12881419,15132976 Process
12288 GO:0060083 IMP acts_upstream_of_or_within smooth muscle contraction involved in micturition 15132976 Process
12288 GO:0086065 IDA acts_upstream_of_or_within cell communication involved in cardiac conduction 32109384 Process
12288 GO:0098703 IDA acts_upstream_of_or_within calcium ion import across plasma membrane 32109384 Process