Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 12558
  • Symbol: Cdh2
  • Description: cadherin 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12558 GO:0003323 IMP involved_in type B pancreatic cell development 26750727 Process
12558 GO:0007043 IMP involved_in cell-cell junction assembly 26750727 Process
12558 GO:0007155 IDA acts_upstream_of_or_within cell adhesion 12738802,14657280 Process
12558 GO:0007156 IDA acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules 8270638,14561752 Process
12558 GO:0007157 IDA acts_upstream_of_or_within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 8270638 Process
12558 GO:0010001 IDA involved_in glial cell differentiation 24952463 Process
12558 GO:0014032 IMP involved_in neural crest cell development 26750727 Process
12558 GO:0016339 IDA acts_upstream_of_or_within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 14561752 Process
12558 GO:0016477 IDA acts_upstream_of_or_within cell migration 14561752 Process
12558 GO:0021537 IGI acts_upstream_of_or_within telencephalon development 25100583 Process
12558 GO:0021987 IGI acts_upstream_of_or_within cerebral cortex development 25100583 Process
12558 GO:0043410 IGI acts_upstream_of_or_within positive regulation of MAPK cascade 20160094 Process
12558 GO:0044331 IDA involved_in cell-cell adhesion mediated by cadherin 24952463 Process
12558 GO:0048514 IMP acts_upstream_of_or_within blood vessel morphogenesis 15809310 Process
12558 GO:0048854 IGI acts_upstream_of_or_within brain morphogenesis 25100583 Process
12558 GO:0048872 IGI acts_upstream_of_or_within homeostasis of number of cells 25100583 Process
12558 GO:0051146 IGI acts_upstream_of_or_within striated muscle cell differentiation 20160094 Process
12558 GO:0060019 IGI acts_upstream_of_or_within radial glial cell differentiation 25100583 Process
12558 GO:0060563 IGI acts_upstream_of_or_within neuroepithelial cell differentiation 25100583 Process
12558 GO:0070445 IGI acts_upstream_of_or_within regulation of oligodendrocyte progenitor proliferation 25100583 Process
12558 GO:0072659 IDA involved_in protein localization to plasma membrane 24046456 Process
12558 GO:0090090 IGI acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway 19075000 Process
12558 GO:0090497 IMP acts_upstream_of_or_within mesenchymal cell migration 17507657 Process
12558 GO:0097091 IMP involved_in synaptic vesicle clustering 34702855 Process
12558 GO:0097118 IMP involved_in neuroligin clustering involved in postsynaptic membrane assembly 20534458 Process
12558 GO:0097150 IDA involved_in neuronal stem cell population maintenance 24952463 Process
12558 GO:0098609 IDA involved_in cell-cell adhesion 9655503 Process
12558 GO:1902897 IMP involved_in regulation of postsynaptic density protein 95 clustering 20534458 Process
12558 GO:2000809 IMP involved_in positive regulation of synaptic vesicle clustering 20534458 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12558 GO:0003723 IDA enables RNA binding 27783602 Function
12558 GO:0005509 IDA enables calcium ion binding 9655503 Function
12558 GO:0005515 IPI enables protein binding 11106648,11719554,15192701,15272007,15834408,16973135,18794329..... Function
12558 GO:0019899 IPI enables enzyme binding 24952463 Function
12558 GO:0019901 IPI enables protein kinase binding 23392350 Function
12558 GO:0019903 IPI enables protein phosphatase binding 16973135 Function
12558 GO:0042802 IPI enables identical protein binding 20190754,21300292,21572446 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12558 GO:0005886 IDA located_in plasma membrane 9655503,17507657,26403541 Component
12558 GO:0005911 IDA located_in cell-cell junction 21296051,24338362,26750727 Component
12558 GO:0005912 IDA located_in adherens junction 12052883,12203715,12695331,15479741,16892058,18239929,29211732..... Component
12558 GO:0005916 IDA located_in fascia adherens 11732910 Component
12558 GO:0009986 IDA located_in cell surface 25232112 Component
12558 GO:0014069 IDA located_in postsynaptic density 20668183 Component
12558 GO:0014704 IDA located_in intercalated disc 17884088,23392350,26187182,26403541 Component
12558 GO:0016323 IDA located_in basolateral plasma membrane 25512490 Component
12558 GO:0016324 IDA located_in apical plasma membrane 21947081 Component
12558 GO:0016327 IDA located_in apicolateral plasma membrane 29211732 Component
12558 GO:0030027 IDA located_in lamellipodium 14657280 Component
12558 GO:0030057 IDA located_in desmosome 15479741 Component
12558 GO:0042383 IDA located_in sarcolemma 23392350 Component
12558 GO:0044853 IDA located_in plasma membrane raft 24046456 Component
12558 GO:0045202 IDA located_in synapse 14622577 Component