Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 13645
  • Symbol: Egf
  • Description: epidermal growth factor

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13645 GO:0005154 IDA enables epidermal growth factor receptor binding 6315706,7678348 Function
13645 GO:0005515 IPI enables protein binding 17626015 Function
13645 GO:0030297 IDA enables transmembrane receptor protein tyrosine kinase activator activity 6248866,7752576,9529375,11823423,12761849,14627991,22822073..... Function
13645 GO:0048018 IDA enables receptor ligand activity 6248866,7752576,9529375,11823423,12761849,14627991,22822073..... Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13645 GO:0005615 IDA is_active_in extracellular space 6248866,7752576,12761849,22822073 Component
13645 GO:0005615 IDA located_in extracellular space 7641815,8240367 Component
13645 GO:0005886 IDA located_in plasma membrane 17626015 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
13645 GO:0007173 IDA acts_upstream_of_or_within epidermal growth factor receptor signaling pathway 6315706,15695332 Process
13645 GO:0007173 IDA involved_in epidermal growth factor receptor signaling pathway 6248866,7752576,9529375,12761849 Process
13645 GO:0007173 IGI acts_upstream_of_or_within epidermal growth factor receptor signaling pathway 7641815 Process
13645 GO:0008283 IGI acts_upstream_of cell population proliferation 15509736 Process
13645 GO:0008284 IDA acts_upstream_of_or_within positive regulation of cell population proliferation 8702723,14712229,15695332 Process
13645 GO:0008284 IGI acts_upstream_of_or_within positive regulation of cell population proliferation 7641815,15051883 Process
13645 GO:0018108 IDA acts_upstream_of_or_within peptidyl-tyrosine phosphorylation 14561752 Process
13645 GO:0021930 IDA acts_upstream_of cerebellar granule cell precursor proliferation 10027293 Process
13645 GO:0021940 IDA acts_upstream_of_or_within positive regulation of cerebellar granule cell precursor proliferation 10027293 Process
13645 GO:0038134 IDA involved_in ERBB2-EGFR signaling pathway 22822073 Process
13645 GO:0043388 IDA involved_in positive regulation of DNA binding 15156153 Process
13645 GO:0043410 IDA acts_upstream_of_or_within positive regulation of MAPK cascade 9030684,16339969 Process
13645 GO:0046425 IDA involved_in regulation of receptor signaling pathway via JAK-STAT 15156153 Process
13645 GO:0048754 IDA acts_upstream_of_or_within branching morphogenesis of an epithelial tube 15831470 Process
13645 GO:0050673 IGI acts_upstream_of epithelial cell proliferation 15509736 Process
13645 GO:0050679 IGI acts_upstream_of_or_within positive regulation of epithelial cell proliferation 15509736 Process
13645 GO:0050730 IDA acts_upstream_of_or_within regulation of peptidyl-tyrosine phosphorylation 11940581 Process
13645 GO:0050731 IDA acts_upstream_of_or_within positive regulation of peptidyl-tyrosine phosphorylation 21186272 Process
13645 GO:0060749 IGI acts_upstream_of_or_within mammary gland alveolus development 10331984 Process
13645 GO:0061098 IDA acts_upstream_of_or_within positive regulation of protein tyrosine kinase activity 7678348 Process
13645 GO:0090370 IDA involved_in negative regulation of cholesterol efflux 20037141 Process
13645 GO:2000060 IDA involved_in positive regulation of ubiquitin-dependent protein catabolic process 20208556 Process