Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 14360
  • Symbol: Fyn
  • Description: Fyn proto-oncogene

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14360 GO:0001664 IPI enables G protein-coupled receptor binding 23169819 Function
14360 GO:0004672 IDA enables protein kinase activity 11826099 Function
14360 GO:0004713 EXP enables protein tyrosine kinase activity 16709819 Function
14360 GO:0004713 IDA enables protein tyrosine kinase activity 8175795,8196616,10872802,12681493,16841086,17923684,20142099,2..... Function
14360 GO:0005515 IPI enables protein binding 7730365,7799925,8196616,8551236,8631859,9185665,9535845,965550..... Function
14360 GO:0015631 IDA enables tubulin binding 11826099 Function
14360 GO:0043014 IDA enables alpha-tubulin binding 11826099 Function
14360 GO:0044325 IPI enables transmembrane transporter binding 12538589 Function
14360 GO:0048156 IPI enables tau protein binding 11826099 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14360 GO:0001764 IGI acts_upstream_of_or_within neuron migration 16162939 Process
14360 GO:0001764 IMP acts_upstream_of_or_within neuron migration 15073522 Process
14360 GO:0003015 IGI involved_in heart process 27525436 Process
14360 GO:0006468 IMP acts_upstream_of_or_within protein phosphorylation 9892651,16190898 Process
14360 GO:0007166 IDA acts_upstream_of_or_within cell surface receptor signaling pathway 9177270 Process
14360 GO:0007249 IGI acts_upstream_of I-kappaB kinase/NF-kappaB signaling 23169819 Process
14360 GO:0008360 IDA acts_upstream_of_or_within regulation of cell shape 11826099 Process
14360 GO:0010629 IMP involved_in negative regulation of gene expression 20978343 Process
14360 GO:0010976 IGI acts_upstream_of_or_within positive regulation of neuron projection development 18354028 Process
14360 GO:0016567 IDA acts_upstream_of protein ubiquitination 24627473 Process
14360 GO:0018108 IDA acts_upstream_of_or_within peptidyl-tyrosine phosphorylation 8175795,8196616,10872802,17923684 Process
14360 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 12681493,28598420 Process
14360 GO:0018108 IMP acts_upstream_of_or_within peptidyl-tyrosine phosphorylation 9381182,17923684 Process
14360 GO:0018108 IMP involved_in peptidyl-tyrosine phosphorylation 27525436 Process
14360 GO:0030163 IMP acts_upstream_of protein catabolic process 16841086 Process
14360 GO:0030900 IGI acts_upstream_of_or_within forebrain development 16162939 Process
14360 GO:0030900 IMP acts_upstream_of_or_within forebrain development 15073522 Process
14360 GO:0031175 IGI acts_upstream_of neuron projection development 18354028 Process
14360 GO:0031397 IDA acts_upstream_of_or_within negative regulation of protein ubiquitination 24627473 Process
14360 GO:0036120 IDA acts_upstream_of_or_within cellular response to platelet-derived growth factor stimulus 17623777 Process
14360 GO:0042177 IMP acts_upstream_of_or_within negative regulation of protein catabolic process 16841086 Process
14360 GO:0042531 IMP involved_in positive regulation of tyrosine phosphorylation of STAT protein 23438599 Process
14360 GO:0043123 IGI acts_upstream_of_or_within positive regulation of I-kappaB kinase/NF-kappaB signaling 23169819 Process
14360 GO:0045471 IGI acts_upstream_of_or_within response to ethanol 9381182 Process
14360 GO:0046777 IDA acts_upstream_of_or_within protein autophosphorylation 8175795 Process
14360 GO:0048813 IMP acts_upstream_of_or_within dendrite morphogenesis 12372285 Process
14360 GO:0050730 IGI involved_in regulation of peptidyl-tyrosine phosphorylation 22820466 Process
14360 GO:0050798 IMP acts_upstream_of_or_within activated T cell proliferation 1516132 Process
14360 GO:0050804 IDA involved_in modulation of chemical synaptic transmission 1361685 Process
14360 GO:0050804 IMP involved_in modulation of chemical synaptic transmission 1361685 Process
14360 GO:0050966 IMP acts_upstream_of_or_within detection of mechanical stimulus involved in sensory perception of pain 16190898 Process
14360 GO:0071560 IGI acts_upstream_of_or_within cellular response to transforming growth factor beta stimulus 21829547 Process
14360 GO:0090314 IGI involved_in positive regulation of protein targeting to membrane 22820466 Process
14360 GO:1900182 IDA acts_upstream_of_or_within positive regulation of protein localization to nucleus 20142099 Process
14360 GO:1900182 IMP involved_in positive regulation of protein localization to nucleus 20142099 Process
14360 GO:1900449 IGI involved_in regulation of glutamate receptor signaling pathway 22820466 Process
14360 GO:1901216 IGI involved_in positive regulation of neuron death 22820466 Process
14360 GO:1902951 IGI involved_in negative regulation of dendritic spine maintenance 22820466 Process
14360 GO:1904645 IGI involved_in response to amyloid-beta 22820466 Process
14360 GO:1905664 IGI involved_in regulation of calcium ion import across plasma membrane 22820466 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
14360 GO:0005768 IDA located_in endosome 17623777 Component
14360 GO:0005884 IDA located_in actin filament 17623777 Component
14360 GO:0005886 IDA located_in plasma membrane 10557075 Component
14360 GO:0014069 IMP located_in postsynaptic density 20655099 Component
14360 GO:0030425 IMP located_in dendrite 20655099 Component
14360 GO:0044297 IDA located_in cell body 11826099 Component
14360 GO:0045121 IDA located_in membrane raft 11826099 Component
14360 GO:0071944 IDA located_in cell periphery 17623777 Component
14360 GO:0097386 IDA located_in glial cell projection 11826099 Component
14360 GO:0098685 IDA is_active_in Schaffer collateral - CA1 synapse 1361685 Component
14360 GO:0098685 IMP is_active_in Schaffer collateral - CA1 synapse 1361685 Component