Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 17096
  • Symbol: Lyn
  • Description: LYN proto-oncogene, Src family tyrosine kinase

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17096 GO:0001782 IMP involved_in B cell homeostasis 9252121 Process
17096 GO:0001817 IMP involved_in regulation of cytokine production 16272347,20385881 Process
17096 GO:0001933 IMP involved_in negative regulation of protein phosphorylation 14525964 Process
17096 GO:0002431 IMP involved_in Fc receptor mediated stimulatory signaling pathway 16272347 Process
17096 GO:0002513 IMP involved_in tolerance induction to self antigen 9252121 Process
17096 GO:0002576 IMP involved_in platelet degranulation 20189992 Process
17096 GO:0002762 IMP involved_in negative regulation of myeloid leukocyte differentiation 11672542 Process
17096 GO:0002768 IMP involved_in immune response-regulating cell surface receptor signaling pathway 9252121 Process
17096 GO:0002774 IMP involved_in Fc receptor mediated inhibitory signaling pathway 16272347 Process
17096 GO:0002902 IMP involved_in regulation of B cell apoptotic process 9064343 Process
17096 GO:0008284 IMP involved_in positive regulation of cell population proliferation 10713104,11435302 Process
17096 GO:0008285 IMP involved_in negative regulation of cell population proliferation 14726379,16116174 Process
17096 GO:0009725 IDA involved_in response to hormone 10713104 Process
17096 GO:0018108 IDA acts_upstream_of_or_within peptidyl-tyrosine phosphorylation 7499277,10872802,16249387 Process
17096 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 11672542,12681493 Process
17096 GO:0018108 IMP involved_in peptidyl-tyrosine phosphorylation 28098138 Process
17096 GO:0030097 IMP involved_in hemopoiesis 11672542 Process
17096 GO:0030218 IMP involved_in erythrocyte differentiation 10713104 Process
17096 GO:0030335 IMP involved_in positive regulation of cell migration 11435302 Process
17096 GO:0030889 IMP involved_in negative regulation of B cell proliferation 9252121 Process
17096 GO:0031175 IMP acts_upstream_of_or_within neuron projection development 19118221 Process
17096 GO:0031663 IMP involved_in lipopolysaccharide-mediated signaling pathway 20385881 Process
17096 GO:0033003 IMP involved_in regulation of mast cell activation 16272347 Process
17096 GO:0034136 IMP involved_in negative regulation of toll-like receptor 2 signaling pathway 20385881 Process
17096 GO:0034142 IMP involved_in toll-like receptor 4 signaling pathway 28098138 Process
17096 GO:0034144 IMP involved_in negative regulation of toll-like receptor 4 signaling pathway 20385881 Process
17096 GO:0035556 IDA acts_upstream_of_or_within intracellular signal transduction 9000133 Process
17096 GO:0042531 IMP involved_in positive regulation of tyrosine phosphorylation of STAT protein 10713104 Process
17096 GO:0043304 IMP involved_in regulation of mast cell degranulation 16272347 Process
17096 GO:0043407 IMP involved_in negative regulation of MAP kinase activity 9252121 Process
17096 GO:0043552 IMP involved_in positive regulation of phosphatidylinositol 3-kinase activity 8128248 Process
17096 GO:0045646 IMP involved_in regulation of erythrocyte differentiation 10594694 Process
17096 GO:0046777 IDA acts_upstream_of_or_within protein autophosphorylation 7499277,9000133 Process
17096 GO:0046777 IDA involved_in protein autophosphorylation 11672542 Process
17096 GO:0050727 IMP involved_in regulation of inflammatory response 16034130 Process
17096 GO:0050853 IDA acts_upstream_of_or_within B cell receptor signaling pathway 7499277 Process
17096 GO:0050853 IGI acts_upstream_of_or_within B cell receptor signaling pathway 23509253 Process
17096 GO:0050855 IMP involved_in regulation of B cell receptor signaling pathway 11672542 Process
17096 GO:0051279 IGI acts_upstream_of_or_within regulation of release of sequestered calcium ion into cytosol 23509253 Process
17096 GO:0070372 IMP involved_in regulation of ERK1 and ERK2 cascade 9252121 Process
17096 GO:0070373 IMP involved_in negative regulation of ERK1 and ERK2 cascade 14525964,14726379 Process
17096 GO:0070667 IMP involved_in negative regulation of mast cell proliferation 14525964 Process
17096 GO:0090330 IMP involved_in regulation of platelet aggregation 20189992 Process
17096 GO:0097028 IMP involved_in dendritic cell differentiation 16034130 Process
17096 GO:1902532 IMP involved_in negative regulation of intracellular signal transduction 14525964 Process
17096 GO:2000670 IMP involved_in positive regulation of dendritic cell apoptotic process 16116174 Process

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17096 GO:0004672 IDA enables protein kinase activity 9000133 Function
17096 GO:0004713 EXP enables protein tyrosine kinase activity 8629002,12504103 Function
17096 GO:0004713 IDA enables protein tyrosine kinase activity 7499277,10872802,11672542,12681493 Function
17096 GO:0004715 IMP enables non-membrane spanning protein tyrosine kinase activity 28098138 Function
17096 GO:0005515 IPI enables protein binding 8395016,10713104,11739737,12681493,16249387,17640867,19171907,..... Function
17096 GO:0017124 IPI enables SH3 domain binding 19064729 Function
17096 GO:0044877 IPI enables protein-containing complex binding 19064729 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
17096 GO:0005634 IDA located_in nucleus 10713104 Component
17096 GO:0005737 IDA located_in cytoplasm 10713104 Component
17096 GO:0005886 IDA located_in plasma membrane 19064729 Component
17096 GO:0032991 IDA part_of protein-containing complex 12681493 Component
17096 GO:0045121 IDA located_in membrane raft 11826099 Component