Gene Ontology

Gene Info

• Species: Rat (Rattus norvegicus)
• GeneID: 171104
• Symbol: Gper1
• Description: G protein-coupled estrogen receptor 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
171104	GO:0001934	IMP	involved_in	positive regulation of protein phosphorylation	20445128	Process
171104	GO:0007210	IMP	involved_in	serotonin receptor signaling pathway	19095043	Process
171104	GO:0008285	IDA	involved_in	negative regulation of cell population proliferation	23907461	Process
171104	GO:0010628	IDA	involved_in	positive regulation of gene expression	23907461	Process
171104	GO:0010628	IMP	involved_in	positive regulation of gene expression	23641788	Process
171104	GO:0010629	IDA	involved_in	negative regulation of gene expression	23907461	Process
171104	GO:0014068	IDA	involved_in	positive regulation of phosphatidylinositol 3-kinase signaling	19717735	Process
171104	GO:0030263	IDA	involved_in	apoptotic chromosome condensation	23907461	Process
171104	GO:0030264	IDA	involved_in	nuclear fragmentation involved in apoptotic nuclear change	23907461	Process
171104	GO:0030518	IDA	involved_in	intracellular steroid hormone receptor signaling pathway	20445128	Process
171104	GO:0030520	IMP	involved_in	intracellular estrogen receptor signaling pathway	20445128	Process
171104	GO:0042307	IMP	involved_in	positive regulation of protein import into nucleus	24262995	Process
171104	GO:0042311	IDA	acts_upstream_of_positive_effect	vasodilation	23283935	Process
171104	GO:0042311	IMP	involved_in	vasodilation	30354811	Process
171104	GO:0043065	IDA	involved_in	positive regulation of apoptotic process	23907461	Process
171104	GO:0043065	IMP	involved_in	positive regulation of apoptotic process	22975889	Process
171104	GO:0043280	IDA	involved_in	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	23907461	Process
171104	GO:0045742	IMP	involved_in	positive regulation of epidermal growth factor receptor signaling pathway	20445128	Process
171104	GO:0051897	IMP	involved_in	positive regulation of protein kinase B signaling	19717735	Process
171104	GO:0070374	IDA	involved_in	positive regulation of ERK1 and ERK2 cascade	19717735,20445128,23283935,23907461	Process
171104	GO:0070374	IMP	involved_in	positive regulation of ERK1 and ERK2 cascade	19717735	Process
171104	GO:0071389	IDA	involved_in	cellular response to mineralocorticoid stimulus	23283935	Process
171104	GO:0071392	IDA	involved_in	cellular response to estradiol stimulus	23283935,23907461	Process
171104	GO:0090200	IDA	involved_in	positive regulation of release of cytochrome c from mitochondria	23907461	Process
171104	GO:1900121	IMP	involved_in	negative regulation of receptor binding	24262995	Process
171104	GO:1905152	IMP	involved_in	positive regulation of voltage-gated sodium channel activity	24097558	Process
171104	GO:2000353	IDA	involved_in	positive regulation of endothelial cell apoptotic process	23283935	Process
171104	GO:2001238	IDA	involved_in	positive regulation of extrinsic apoptotic signaling pathway	23907461	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
171104	GO:0005737	IDA	located_in	cytoplasm	22919059	Component
171104	GO:0005789	IDA	located_in	endoplasmic reticulum membrane	24262995	Component
171104	GO:0005794	IDA	located_in	Golgi apparatus	22919059	Component
171104	GO:0005886	IDA	located_in	plasma membrane	22919059	Component
171104	GO:0014069	IDA	located_in	postsynaptic density	22919059,23822769	Component
171104	GO:0030424	IDA	located_in	axon	22919059	Component
171104	GO:0030425	IDA	located_in	dendrite	22919059	Component
171104	GO:0031966	IDA	located_in	mitochondrial membrane	22919059	Component
171104	GO:0032591	IDA	located_in	dendritic spine membrane	22919059,23822769	Component
171104	GO:0042734	IDA	located_in	presynaptic membrane	23822769	Component
171104	GO:0043025	IDA	located_in	neuronal cell body	19095043	Component
171104	GO:0043198	IDA	located_in	dendritic shaft	22919059,23822769	Component
171104	GO:0043679	IDA	located_in	axon terminus	22919059	Component
171104	GO:0044327	IDA	located_in	dendritic spine head	22919059	Component
171104	GO:0048786	IDA	located_in	presynaptic active zone	23822769	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
171104	GO:0038054	IDA	enables	G protein-coupled estrogen receptor activity	23283935	Function
171104	GO:1903924	IMP	enables	estradiol binding	24262995	Function