Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18750
  • Symbol: Prkca
  • Description: protein kinase C, alpha

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18750 GO:0001933 IGI acts_upstream_of_or_within negative regulation of protein phosphorylation 24305805 Process
18750 GO:0001933 IMP acts_upstream_of_or_within negative regulation of protein phosphorylation 14966518 Process
18750 GO:0001934 IMP acts_upstream_of_or_within positive regulation of protein phosphorylation 14966518 Process
18750 GO:0002026 IMP acts_upstream_of_or_within regulation of the force of heart contraction 14966518 Process
18750 GO:0002062 IDA acts_upstream_of_or_within chondrocyte differentiation 17644814 Process
18750 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 7741753,12618484 Process
18750 GO:0006468 IDA involved_in protein phosphorylation 31578312 Process
18750 GO:0006468 IGI acts_upstream_of protein phosphorylation 24305805 Process
18750 GO:0006468 IMP acts_upstream_of protein phosphorylation 14966518 Process
18750 GO:0006469 IMP acts_upstream_of_or_within negative regulation of protein kinase activity 11923480 Process
18750 GO:0006874 IMP acts_upstream_of_or_within intracellular calcium ion homeostasis 14966518 Process
18750 GO:0006937 IMP acts_upstream_of_or_within regulation of muscle contraction 14966518 Process
18750 GO:0008283 IGI acts_upstream_of cell population proliferation 17956267 Process
18750 GO:0008285 IGI acts_upstream_of_or_within negative regulation of cell population proliferation 17956267 Process
18750 GO:0010360 IMP involved_in negative regulation of anion channel activity 7828597 Process
18750 GO:0030593 IMP acts_upstream_of_or_within neutrophil chemotaxis 12928424 Process
18750 GO:0036289 IDA acts_upstream_of_or_within peptidyl-serine autophosphorylation 16814779 Process
18750 GO:0043409 IMP acts_upstream_of_or_within negative regulation of MAPK cascade 11923480 Process
18750 GO:0045651 IMP involved_in positive regulation of macrophage differentiation 9508782 Process
18750 GO:0045780 IMP involved_in positive regulation of bone resorption 16014375 Process
18750 GO:0046325 IMP acts_upstream_of_or_within negative regulation of glucose import 11923480 Process
18750 GO:0046627 IMP acts_upstream_of_or_within negative regulation of insulin receptor signaling pathway 11923480 Process
18750 GO:0046716 IMP acts_upstream_of_or_within muscle cell cellular homeostasis 14966518 Process
18750 GO:0047484 IMP involved_in regulation of response to osmotic stress 7828597 Process
18750 GO:0048863 IDA acts_upstream_of_or_within stem cell differentiation 17644814 Process
18750 GO:0050729 IMP acts_upstream_of_or_within positive regulation of inflammatory response 12928424 Process
18750 GO:0050730 IMP acts_upstream_of_or_within regulation of peptidyl-tyrosine phosphorylation 11940581 Process
18750 GO:0050930 IMP acts_upstream_of_or_within induction of positive chemotaxis 12928424 Process
18750 GO:0071322 IDA acts_upstream_of_or_within cellular response to carbohydrate stimulus 16585392 Process
18750 GO:0090330 IMP involved_in regulation of platelet aggregation 19147982 Process
18750 GO:0097193 IMP acts_upstream_of_or_within intrinsic apoptotic signaling pathway 12928424 Process
18750 GO:0099171 IDA involved_in presynaptic modulation of chemical synaptic transmission 21658591 Process
18750 GO:0099171 IMP involved_in presynaptic modulation of chemical synaptic transmission 21658591 Process
18750 GO:2000300 IDA involved_in regulation of synaptic vesicle exocytosis 21658591 Process
18750 GO:2000300 IMP involved_in regulation of synaptic vesicle exocytosis 21658591 Process
18750 GO:2000707 IMP involved_in positive regulation of dense core granule biogenesis 19147982 Process

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18750 GO:0004674 IDA enables protein serine/threonine kinase activity 14966518 Function
18750 GO:0004697 IDA enables protein kinase C activity 12618484,12970181,23099255 Function
18750 GO:0004697 IMP enables protein kinase C activity 7828597 Function
18750 GO:0004698 IDA enables calcium-dependent protein kinase C activity 7741753,10879655 Function
18750 GO:0004698 IMP enables calcium-dependent protein kinase C activity 7828597 Function
18750 GO:0005178 IPI enables integrin binding 16014375 Function
18750 GO:0005515 IPI enables protein binding 12618484,17347670,19966277,31578312 Function
18750 GO:0008289 EXP enables lipid binding 23762412 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18750 GO:0005634 IDA located_in nucleus 10882525,14613966,15590069 Component
18750 GO:0005737 IDA located_in cytoplasm 10882525,12826667,12928424,14613966,23824537 Component
18750 GO:0005739 IDA located_in mitochondrion 12826667 Component
18750 GO:0005886 IDA located_in plasma membrane 10882525 Component
18750 GO:0014704 IDA located_in intercalated disc 27353086 Component
18750 GO:0016020 IDA located_in membrane 18323529 Component
18750 GO:0030424 IDA located_in axon 18265009 Component
18750 GO:0030425 IDA located_in dendrite 12115694 Component
18750 GO:0032991 IDA part_of protein-containing complex 27353086 Component
18750 GO:0035866 IDA part_of alphav-beta3 integrin-PKCalpha complex 16014375 Component
18750 GO:0043025 IDA located_in neuronal cell body 12115694 Component
18750 GO:0044305 IDA is_active_in calyx of Held 21658591 Component
18750 GO:0044305 IMP is_active_in calyx of Held 21658591 Component
18750 GO:0045177 IDA located_in apical part of cell 23863479 Component
18750 GO:0098793 IMP located_in presynapse 21658591 Component
18750 GO:0099523 IDA is_active_in presynaptic cytosol 21658591 Component
18750 GO:0120199 IDA located_in cone photoreceptor outer segment 10813773 Component
18750 GO:1990917 IDA located_in ooplasm 15590069 Component