Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 19766
  • Symbol: Ripk1
  • Description: receptor (TNFRSF)-interacting serine-threonine kinase 1

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19766 GO:0004672 IMP enables protein kinase activity 29440439 Function
19766 GO:0004674 IDA enables protein serine/threonine kinase activity 28701375 Function
19766 GO:0004674 IMP enables protein serine/threonine kinase activity 27819682,30988283,31511692,31519886,31519887,31827281..... Function
19766 GO:0005515 IPI enables protein binding 16680093,17702576,18022363,18246070,18719121,18946037,19524513..... Function
19766 GO:0042803 IDA enables protein homodimerization activity 29440439 Function

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19766 GO:0006915 IMP involved_in apoptotic process 28842570,29440439,30867408,31511692,31519886,31519887..... Process
19766 GO:0036289 IMP involved_in peptidyl-serine autophosphorylation 31827281 Process
19766 GO:0042327 IMP involved_in positive regulation of phosphorylation 21052097 Process
19766 GO:0043066 IMP involved_in negative regulation of apoptotic process 24813849,24813850,27819682,30185824 Process
19766 GO:0043123 IMP acts_upstream_of_or_within positive regulation of I-kappaB kinase/NF-kappaB signaling 22089168 Process
19766 GO:0043410 IMP involved_in positive regulation of MAPK cascade 20125124 Process
19766 GO:0046330 IMP involved_in positive regulation of JNK cascade 20125124 Process
19766 GO:0046777 IMP involved_in protein autophosphorylation 29440439 Process
19766 GO:0050729 IMP involved_in positive regulation of inflammatory response 31827281 Process
19766 GO:0051092 IMP involved_in positive regulation of NF-kappaB transcription factor activity 20125124,31519886,31519887 Process
19766 GO:0051347 IGI acts_upstream_of_or_within positive regulation of transferase activity 19498109 Process
19766 GO:0060546 IMP involved_in negative regulation of necroptotic process 24813849,24813850,27819681,27819682 Process
19766 GO:0070105 IMP involved_in positive regulation of interleukin-6-mediated signaling pathway 31827281 Process
19766 GO:0070231 IMP involved_in T cell apoptotic process 21876153 Process
19766 GO:0070266 IDA involved_in necroptotic process 28701375 Process
19766 GO:0070266 IGI acts_upstream_of_or_within necroptotic process 19498109,21052097,22037414 Process
19766 GO:0070266 IMP involved_in necroptotic process 28842570,29440439,30867408,30988283,31519886,31519887..... Process
19766 GO:0070301 IMP involved_in cellular response to hydrogen peroxide 27258785 Process
19766 GO:0071363 IMP involved_in cellular response to growth factor stimulus 20125124 Process
19766 GO:0097300 IMP involved_in programmed necrotic cell death 27258785 Process
19766 GO:0097527 IMP involved_in necroptotic signaling pathway 21876153,31827281 Process
19766 GO:1901026 IGI acts_upstream_of_or_within ripoptosome assembly involved in necroptotic process 21052097 Process
19766 GO:1903265 IDA involved_in positive regulation of tumor necrosis factor-mediated signaling pathway 30439713 Process
19766 GO:2000377 IMP acts_upstream_of_or_within regulation of reactive oxygen species metabolic process 21052097 Process
19766 GO:2001237 IGI acts_upstream_of_or_within negative regulation of extrinsic apoptotic signaling pathway 22089168 Process
19766 GO:2001238 IGI acts_upstream_of_or_within positive regulation of extrinsic apoptotic signaling pathway 19498109 Process
19766 GO:2001240 IMP involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 20125124 Process