Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2043
  • Symbol: EPHA4
  • Description: EPH receptor A4

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2043 GO:0004672 IDA enables protein kinase activity 12775584 Function
2043 GO:0005515 IPI enables protein binding 12775584,19836338,23812375,28514442,35384245 Function
2043 GO:0016301 IGI enables kinase activity 24217950 Function
2043 GO:0042731 IPI enables PH domain binding 12775584 Function
2043 GO:0097161 IDA enables DH domain binding 12775584 Function
2043 GO:1990782 IPI enables protein tyrosine kinase binding 24217950 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2043 GO:0007162 IMP involved_in negative regulation of cell adhesion 29093007 Process
2043 GO:0008284 IGI involved_in positive regulation of cell population proliferation 28795314 Process
2043 GO:0010719 IMP involved_in negative regulation of epithelial to mesenchymal transition 29093007 Process
2043 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 12775584 Process
2043 GO:0030335 IDA involved_in positive regulation of cell migration 28795314 Process
2043 GO:0030336 IMP involved_in negative regulation of cell migration 22996586,29093007 Process
2043 GO:0045785 IMP involved_in positive regulation of cell adhesion 22996586 Process
2043 GO:0046777 IDA involved_in protein autophosphorylation 12775584 Process
2043 GO:0048013 IGI involved_in ephrin receptor signaling pathway 24217950 Process
2043 GO:0050821 IGI involved_in protein stabilization 24217950 Process
2043 GO:0070373 IDA involved_in negative regulation of ERK1 and ERK2 cascade 29093007 Process
2043 GO:1900038 IMP acts_upstream_of_or_within negative regulation of cellular response to hypoxia 31150684 Process
2043 GO:1902004 IGI involved_in positive regulation of amyloid-beta formation 24217950 Process
2043 GO:1902961 IGI involved_in positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 24217950 Process
2043 GO:1903051 IGI involved_in negative regulation of proteolysis involved in protein catabolic process 24217950 Process
2043 GO:2001108 IDA involved_in positive regulation of Rho guanyl-nucleotide exchange factor activity 12775584 Process