Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 208
  • Symbol: AKT2
  • Description: AKT serine/threonine kinase 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
208 GO:0004674 IDA enables protein serine/threonine kinase activity 10983986,16540465 Function
208 GO:0005515 IPI enables protein binding 10490823,10983986,12434148,16417406,16792529,17030088,19713527..... Function
208 GO:0005524 IDA enables ATP binding 16540465 Function
208 GO:0140677 EXP enables molecular function activator activity 12517337 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
208 GO:0005634 IDA located_in nucleus 20059950 Component
208 GO:0005654 IDA located_in nucleoplasm Component
208 GO:0005829 IDA located_in cytosol Component
208 GO:0032991 IDA part_of protein-containing complex 10983986 Component
208 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
208 GO:0008284 IMP involved_in positive regulation of cell population proliferation 10983986 Process
208 GO:0008286 IMP involved_in insulin receptor signaling pathway 16814735 Process
208 GO:0010748 IMP involved_in negative regulation of long-chain fatty acid import across plasma membrane 16814735 Process
208 GO:0010907 IMP involved_in positive regulation of glucose metabolic process 16814735 Process
208 GO:0010918 IMP involved_in positive regulation of mitochondrial membrane potential 10983986 Process
208 GO:0030335 IDA involved_in positive regulation of cell migration 25428377 Process
208 GO:0032000 IMP involved_in positive regulation of fatty acid beta-oxidation 16814735 Process
208 GO:0032869 IMP involved_in cellular response to insulin stimulus 16814735 Process
208 GO:0043066 IMP involved_in negative regulation of apoptotic process 10983986 Process
208 GO:0045725 IMP involved_in positive regulation of glycogen biosynthetic process 16814735 Process
208 GO:0046326 IMP involved_in positive regulation of glucose import 16814735 Process
208 GO:2000147 IMP involved_in positive regulation of cell motility 17332325 Process