Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 21812
  • Symbol: Tgfbr1
  • Description: transforming growth factor, beta receptor I

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21812 GO:0001501 IGI acts_upstream_of_or_within skeletal system development 16845371 Process
21812 GO:0001525 IMP acts_upstream_of_or_within angiogenesis 11285230 Process
21812 GO:0001701 IMP acts_upstream_of_or_within in utero embryonic development 11285230,14729481,17078885 Process
21812 GO:0001822 IGI acts_upstream_of_or_within kidney development 16845371 Process
21812 GO:0001824 IDA acts_upstream_of_or_within blastocyst development 9921650 Process
21812 GO:0001935 IGI acts_upstream_of endothelial cell proliferation 21832243 Process
21812 GO:0001937 IGI acts_upstream_of_or_within negative regulation of endothelial cell proliferation 21832243 Process
21812 GO:0002088 IMP acts_upstream_of_or_within lens development in camera-type eye 11641223 Process
21812 GO:0003222 IMP involved_in ventricular trabecula myocardium morphogenesis 18718461 Process
21812 GO:0003223 IMP involved_in ventricular compact myocardium morphogenesis 18718461 Process
21812 GO:0003342 IMP NOT involved_in proepicardium development 18718461 Process
21812 GO:0006915 IMP acts_upstream_of apoptotic process 16806156,17078885 Process
21812 GO:0007179 IDA acts_upstream_of_or_within transforming growth factor beta receptor signaling pathway 14580334,15820682 Process
21812 GO:0007179 IGI involved_in transforming growth factor beta receptor signaling pathway 18718461 Process
21812 GO:0007179 IMP acts_upstream_of_or_within transforming growth factor beta receptor signaling pathway 11285230,17078885,21832243 Process
21812 GO:0007507 IMP acts_upstream_of_or_within heart development 17078885 Process
21812 GO:0008354 IMP acts_upstream_of_or_within germ cell migration 15993878 Process
21812 GO:0008584 IMP acts_upstream_of_or_within male gonad development 23342175 Process
21812 GO:0009790 IMP acts_upstream_of_or_within embryo development 14729481,16344855 Process
21812 GO:0009791 IMP acts_upstream_of_or_within post-embryonic development 16806156 Process
21812 GO:0009952 IGI acts_upstream_of_or_within anterior/posterior pattern specification 16845371 Process
21812 GO:0010468 IMP acts_upstream_of_or_within regulation of gene expression 16806156 Process
21812 GO:0010718 IGI involved_in positive regulation of epithelial to mesenchymal transition 18718461 Process
21812 GO:0030199 IMP acts_upstream_of_or_within collagen fibril organization 15993878 Process
21812 GO:0032331 IMP involved_in negative regulation of chondrocyte differentiation 19494318 Process
21812 GO:0043065 IDA involved_in positive regulation of apoptotic process 24835278 Process
21812 GO:0043066 IMP acts_upstream_of_or_within negative regulation of apoptotic process 16806156,17078885 Process
21812 GO:0043393 IMP acts_upstream_of_or_within regulation of protein binding 16601693 Process
21812 GO:0043542 IMP acts_upstream_of_or_within endothelial cell migration 11285230 Process
21812 GO:0046847 IMP acts_upstream_of filopodium assembly 16806156 Process
21812 GO:0048538 IMP acts_upstream_of_or_within thymus development 17078885 Process
21812 GO:0048663 IMP acts_upstream_of_or_within neuron fate commitment 15744664 Process
21812 GO:0048701 IMP acts_upstream_of_or_within embryonic cranial skeleton morphogenesis 16806156 Process
21812 GO:0048705 IGI acts_upstream_of_or_within skeletal system morphogenesis 16845371 Process
21812 GO:0048844 IMP acts_upstream_of_or_within artery morphogenesis 17078885 Process
21812 GO:0051491 IMP acts_upstream_of_or_within positive regulation of filopodium assembly 16806156 Process
21812 GO:0051496 IGI involved_in positive regulation of stress fiber assembly 18718461 Process
21812 GO:0060017 IMP acts_upstream_of_or_within parathyroid gland development 17078885 Process
21812 GO:0060021 IGI acts_upstream_of_or_within roof of mouth development 16845371 Process
21812 GO:0060021 IMP acts_upstream_of_or_within roof of mouth development 16806156 Process
21812 GO:0060037 IMP acts_upstream_of_or_within pharyngeal system development 17078885 Process
21812 GO:0060043 IMP involved_in regulation of cardiac muscle cell proliferation 18718461 Process
21812 GO:0060412 IMP involved_in ventricular septum morphogenesis 18718461 Process
21812 GO:0060978 IMP involved_in angiogenesis involved in coronary vascular morphogenesis 18718461 Process
21812 GO:0060982 IMP involved_in coronary artery morphogenesis 18718461 Process
21812 GO:0070723 IDA involved_in response to cholesterol 17878231 Process
21812 GO:0071560 IDA involved_in cellular response to transforming growth factor beta stimulus 19494318 Process
21812 GO:1905007 IMP involved_in positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation 18718461 Process
21812 GO:1905075 IGI involved_in positive regulation of tight junction disassembly 18718461 Process
21812 GO:1905223 IMP involved_in epicardium morphogenesis 18718461 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21812 GO:0005024 IDA enables transforming growth factor beta receptor activity 15820682,25065622 Function
21812 GO:0005024 IGI enables transforming growth factor beta receptor activity 17878231 Function
21812 GO:0005102 IPI enables signaling receptor binding 25065622,31023188 Function
21812 GO:0005515 IPI enables protein binding 12773577,14580334,15239668,17673906,18337748,20603020,21266196..... Function
21812 GO:0046332 IDA enables SMAD binding 12773577 Function
21812 GO:0050431 IPI enables transforming growth factor beta binding 17878231 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21812 GO:0005768 IDA located_in endosome 21266196 Component