Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 21813
  • Symbol: Tgfbr2
  • Description: transforming growth factor, beta receptor II

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21813 GO:0001569 IMP acts_upstream_of_or_within branching involved in blood vessel morphogenesis 17078885 Process
21813 GO:0001570 IMP involved_in vasculogenesis 12975342 Process
21813 GO:0001701 IMP acts_upstream_of_or_within in utero embryonic development 10030593,18990706 Process
21813 GO:0001947 IMP involved_in heart looping 17050629 Process
21813 GO:0002053 IMP involved_in positive regulation of mesenchymal cell proliferation 12975342 Process
21813 GO:0002088 IMP acts_upstream_of_or_within lens development in camera-type eye 11641223 Process
21813 GO:0002651 IMP acts_upstream_of_or_within positive regulation of tolerance induction to self antigen 16973387 Process
21813 GO:0002663 IMP acts_upstream_of_or_within positive regulation of B cell tolerance induction 16973387 Process
21813 GO:0002666 IMP acts_upstream_of_or_within positive regulation of T cell tolerance induction 16973387 Process
21813 GO:0003148 IMP involved_in outflow tract septum morphogenesis 20652948 Process
21813 GO:0003149 IMP involved_in membranous septum morphogenesis 20652948 Process
21813 GO:0003151 IMP involved_in outflow tract morphogenesis 17050629 Process
21813 GO:0003181 IMP involved_in atrioventricular valve morphogenesis 20652948 Process
21813 GO:0003186 IMP involved_in tricuspid valve morphogenesis 20652948 Process
21813 GO:0003214 IMP involved_in cardiac left ventricle morphogenesis 20652948 Process
21813 GO:0003274 IMP involved_in endocardial cushion fusion 20652948 Process
21813 GO:0003417 IGI acts_upstream_of_or_within growth plate cartilage development 21420963 Process
21813 GO:0003430 IMP acts_upstream_of_or_within growth plate cartilage chondrocyte growth 21420963 Process
21813 GO:0007179 IMP acts_upstream_of_or_within transforming growth factor beta receptor signaling pathway 21420963 Process
21813 GO:0007219 IDA acts_upstream_of_or_within Notch signaling pathway 25446530 Process
21813 GO:0007224 IMP acts_upstream_of_or_within smoothened signaling pathway 18990706 Process
21813 GO:0007369 IMP acts_upstream_of_or_within gastrulation 10030593 Process
21813 GO:0007420 IMP involved_in brain development 12975342 Process
21813 GO:0007507 IMP acts_upstream_of_or_within heart development 16332365,17078885 Process
21813 GO:0010468 IMP acts_upstream_of_or_within regulation of gene expression 21420963 Process
21813 GO:0010634 IMP acts_upstream_of_or_within positive regulation of epithelial cell migration 11641223 Process
21813 GO:0030324 IMP acts_upstream_of_or_within lung development 18990706 Process
21813 GO:0035162 IMP involved_in embryonic hemopoiesis 12975342 Process
21813 GO:0042127 IMP acts_upstream_of_or_within regulation of cell population proliferation 15781643 Process
21813 GO:0045766 IGI acts_upstream_of_or_within positive regulation of angiogenesis 23868260 Process
21813 GO:0048701 IMP involved_in embryonic cranial skeleton morphogenesis 12975342 Process
21813 GO:0051138 IMP acts_upstream_of_or_within positive regulation of NK T cell differentiation 16973387 Process
21813 GO:0051216 IMP involved_in cartilage development 18498113 Process
21813 GO:0060412 IMP involved_in ventricular septum morphogenesis 17050629 Process
21813 GO:0060425 IMP acts_upstream_of_or_within lung morphogenesis 18990706 Process
21813 GO:0060433 IMP acts_upstream_of_or_within bronchus development 18990706 Process
21813 GO:0060434 IMP acts_upstream_of_or_within bronchus morphogenesis 18990706 Process
21813 GO:0060439 IMP acts_upstream_of_or_within trachea morphogenesis 18990706 Process
21813 GO:0060440 IMP acts_upstream_of_or_within trachea formation 18990706 Process
21813 GO:0060443 IMP acts_upstream_of_or_within mammary gland morphogenesis 15781643 Process
21813 GO:0060463 IMP acts_upstream_of_or_within lung lobe morphogenesis 18990706 Process
21813 GO:0061520 IMP acts_upstream_of_or_within Langerhans cell differentiation 17938236 Process
21813 GO:0062009 IMP involved_in secondary palate development 12975342 Process
21813 GO:0070723 IDA involved_in response to cholesterol 17878231 Process
21813 GO:0072091 IMP acts_upstream_of_or_within regulation of stem cell proliferation 12975342 Process
21813 GO:1905007 IMP involved_in positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation 17050629 Process
21813 GO:1905315 IMP NOT involved_in cell proliferation involved in endocardial cushion morphogenesis 20652948 Process
21813 GO:1905316 IMP NOT involved_in superior endocardial cushion morphogenesis 17050629 Process
21813 GO:1905317 IMP involved_in inferior endocardial cushion morphogenesis 17050629 Process
21813 GO:1990086 IDA acts_upstream_of_or_within lens fiber cell apoptotic process 11641223 Process
21813 GO:1990428 IMP involved_in miRNA transport 25801897 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21813 GO:0005024 IGI enables transforming growth factor beta receptor activity 17878231 Function
21813 GO:0005515 IPI enables protein binding 12773577,15239668,17673906,18337748,20603020,21518866,23624079..... Function
21813 GO:0019209 IDA enables kinase activator activity 16806156 Function
21813 GO:0046332 IDA enables SMAD binding 12773577 Function
21813 GO:0050431 IPI enables transforming growth factor beta binding 17878231 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21813 GO:0009897 IDA located_in external side of plasma membrane 16973387 Component