Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2268
  • Symbol: FGR
  • Description: FGR proto-oncogene, Src family tyrosine kinase

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2268 GO:0001784 IPI enables phosphotyrosine residue binding 20624904 Function
2268 GO:0004713 EXP enables protein tyrosine kinase activity 10861086,16921024 Function
2268 GO:0004713 IDA enables protein tyrosine kinase activity 7519620 Function
2268 GO:0004715 IDA enables non-membrane spanning protein tyrosine kinase activity 8327512 Function
2268 GO:0005515 IPI enables protein binding 16273093,22939624,24658140,24728074,24860872,31980649..... Function
2268 GO:0034988 IDA enables Fc-gamma receptor I complex binding 8327512 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2268 GO:0005856 IDA colocalizes_with cytoskeleton 8603737 Component
2268 GO:0005886 IDA located_in plasma membrane Component
2268 GO:0016235 IDA located_in aggresome Component
2268 GO:0070062 HDA located_in extracellular exosome 20458337 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2268 GO:0007229 IMP involved_in integrin-mediated signaling pathway 7519620,10739672 Process
2268 GO:0014068 IMP involved_in positive regulation of phosphatidylinositol 3-kinase signaling 10739672 Process
2268 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 7519620,8327512 Process
2268 GO:0043552 IMP involved_in positive regulation of phosphatidylinositol 3-kinase activity 10739672 Process
2268 GO:0046777 IDA involved_in protein autophosphorylation 2181286,8327512 Process