Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 252972
• Symbol: Tpcn1
• Description: two pore channel 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
252972	GO:0005248	IDA	enables	voltage-gated sodium channel activity	24776928,29562233	Function
252972	GO:0015280	IDA	enables	ligand-gated sodium channel activity	24776928,29562233	Function
252972	GO:0019905	IPI	enables	syntaxin binding	28855648	Function
252972	GO:0042803	IDA	enables	protein homodimerization activity	29562233	Function
252972	GO:0072345	IDA	NOT enables	NAADP-sensitive calcium-release channel activity	24776928	Function
252972	GO:0080025	IDA	enables	phosphatidylinositol-3,5-bisphosphate binding	29562233	Function
252972	GO:0097682	IDA	enables	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity	24776928	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
252972	GO:0016020	IDA	located_in	membrane	29562233	Component
252972	GO:0031901	IDA	located_in	early endosome membrane	28855648	Component
252972	GO:0036019	IDA	located_in	endolysosome	24776928	Component
252972	GO:0055038	IDA	located_in	recycling endosome membrane	28855648	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
252972	GO:0035725	IDA	involved_in	sodium ion transmembrane transport	29562233	Process
252972	GO:0075509	IMP	involved_in	endocytosis involved in viral entry into host cell	25722412	Process