Gene Ontology

Gene Info

  • Species: Fission yeast (Schizosaccharomyces pombe)
  • GeneID: 2539869
  • Symbol: cdc2
  • Description: cyclin-dependent protein kinase Cdk1/Cdc2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2539869 GO:0000082 IMP involved_in G1/S transition of mitotic cell cycle 7254352,9034336 Process
2539869 GO:0000086 IMP involved_in G2/M transition of mitotic cell cycle 2665944,7254352 Process
2539869 GO:0001100 EXP involved_in negative regulation of exit from mitosis 16950131 Process
2539869 GO:0031031 IMP involved_in positive regulation of septation initiation signaling 24920823 Process
2539869 GO:0031138 IMP involved_in negative regulation of conjugation with cellular fusion 18059475 Process
2539869 GO:0031536 IMP involved_in positive regulation of exit from mitosis 16950791 Process
2539869 GO:0031568 IGI involved_in mitotic G1 cell size control checkpoint signaling 9398669 Process
2539869 GO:0031573 IMP involved_in mitotic intra-S DNA damage checkpoint signaling 15297457 Process
2539869 GO:0032436 IMP involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process 9430640 Process
2539869 GO:0042307 IMP involved_in positive regulation of protein import into nucleus 10485849 Process
2539869 GO:0044773 EXP involved_in mitotic DNA damage checkpoint signaling 12023299 Process
2539869 GO:0045732 EXP involved_in positive regulation of protein catabolic process 9755169 Process
2539869 GO:0045842 IMP involved_in positive regulation of mitotic metaphase/anaphase transition 7774573 Process
2539869 GO:0051446 IMP involved_in positive regulation of meiotic cell cycle 7498766 Process
2539869 GO:0061245 IDA involved_in establishment or maintenance of bipolar cell polarity 32878942 Process
2539869 GO:0062123 IMP involved_in regulation of linear element maturation 30640914 Process
2539869 GO:0072435 IGI involved_in response to mitotic G2 DNA damage checkpoint signaling 9042863 Process
2539869 GO:0072435 IMP involved_in response to mitotic G2 DNA damage checkpoint signaling 9278510 Process
2539869 GO:0072435 IPI involved_in response to mitotic G2 DNA damage checkpoint signaling 26131711 Process
2539869 GO:0072441 EXP involved_in response to meiotic DNA replication checkpoint signaling 10521402 Process
2539869 GO:0110044 IDA involved_in regulation of cell cycle switching, mitotic to meiotic cell cycle 26804917 Process
2539869 GO:0110045 IMP involved_in negative regulation of cell cycle switching, mitotic to meiotic cell cycle 17804800 Process
2539869 GO:0140429 EXP involved_in positive regulation of mitotic sister chromatid biorientation 20739936 Process
2539869 GO:0140429 IMP involved_in positive regulation of mitotic sister chromatid biorientation 19523829 Process
2539869 GO:1902413 EXP involved_in negative regulation of mitotic cytokinesis 34402513 Process
2539869 GO:1902424 IMP involved_in negative regulation of attachment of mitotic spindle microtubules to kinetochore 22065639 Process
2539869 GO:1902845 IMP involved_in negative regulation of mitotic spindle elongation 19523829,19686686 Process
2539869 GO:1903380 IMP involved_in positive regulation of mitotic chromosome condensation 10485849 Process
2539869 GO:1903465 EXP involved_in positive regulation of mitotic cell cycle DNA replication 11937031 Process
2539869 GO:1903467 IMP involved_in negative regulation of mitotic DNA replication initiation 9436991,11486016 Process
2539869 GO:1903500 IMP involved_in negative regulation of mitotic actomyosin contractile ring assembly 29343550 Process
2539869 GO:1904514 IMP involved_in positive regulation of initiation of premeiotic DNA replication 7498766 Process
2539869 GO:1904537 IPI involved_in negative regulation of mitotic telomere tethering at nuclear periphery 22959349 Process
2539869 GO:1905263 IMP involved_in positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination 30640914 Process
2539869 GO:1905561 EXP involved_in positive regulation of kinetochore assembly 34810257 Process
2539869 GO:1905757 IMP involved_in negative regulation of primary cell septum biogenesis 29813053 Process
2539869 GO:1905785 IMP involved_in negative regulation of anaphase-promoting complex-dependent catabolic process 10921876,10921878 Process
2539869 GO:1990820 IGI involved_in response to mitotic DNA integrity checkpoint signaling 12186947 Process
2539869 GO:2001033 IMP involved_in negative regulation of double-strand break repair via nonhomologous end joining 25533340 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2539869 GO:0000307 IDA part_of cyclin-dependent protein kinase holoenzyme complex 3322810 Component
2539869 GO:0000307 IPI part_of cyclin-dependent protein kinase holoenzyme complex 2682257 Component
2539869 GO:0000776 EXP is_active_in kinetochore 11683390 Component
2539869 GO:0000785 IDA part_of chromatin 12419251 Component
2539869 GO:0005634 EXP is_active_in nucleus 11683390 Component
2539869 GO:0005634 IDA is_active_in nucleus 2534559,2569363,11084332,29123917 Component
2539869 GO:0005737 EXP is_active_in cytoplasm 11683390 Component
2539869 GO:0035974 EXP is_active_in meiotic spindle pole body 11683390 Component
2539869 GO:0044732 EXP is_active_in mitotic spindle pole body 11683390 Component
2539869 GO:0071957 IDA is_active_in old mitotic spindle pole body 1699136 Component
2539869 GO:0071958 IDA is_active_in new mitotic spindle pole body 1699136 Component
2539869 GO:0072686 EXP is_active_in mitotic spindle 11683390 Component
2539869 GO:0072687 IDA is_active_in meiotic spindle 12606573 Component
2539869 GO:0140445 EXP is_active_in chromosome, telomeric repeat region 29123917 Component
2539869 GO:1990023 IDA is_active_in mitotic spindle midzone 11084332 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2539869 GO:0004672 IDA enables protein kinase activity 2569363,3516412 Function
2539869 GO:0004674 EXP enables protein serine/threonine kinase activity 12606573 Function
2539869 GO:0004674 IDA enables protein serine/threonine kinase activity 20739936,23333317,26804917,31644361,32878942 Function
2539869 GO:0004693 EXP enables cyclin-dependent protein serine/threonine kinase activity 9430640,9755169,16920624,25487150,27984725,29343550,34133210,3..... Function
2539869 GO:0004693 IDA enables cyclin-dependent protein serine/threonine kinase activity 7957097,9177184,9242669,9353247,9436991,10921878,11486016,1178..... Function
2539869 GO:0004693 IGI enables cyclin-dependent protein serine/threonine kinase activity 2569363 Function
2539869 GO:0004693 IMP enables cyclin-dependent protein serine/threonine kinase activity 9303310,9353247,10485849,10921876,19523829 Function
2539869 GO:0004712 EXP enables protein serine/threonine/tyrosine kinase activity 36408846 Function
2539869 GO:0005515 IPI enables protein binding 1372994,1655416,1819507,2569363,2665944,8455610,8552194,888755..... Function
2539869 GO:0097472 IDA enables cyclin-dependent protein kinase activity 2665944,3322810,22665807 Function