Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 25865
• Symbol: PRKD2
• Description: protein kinase D2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
25865	GO:0001938	IGI	involved_in	positive regulation of endothelial cell proliferation	20497126	Process
25865	GO:0001938	IMP	involved_in	positive regulation of endothelial cell proliferation	19001381	Process
25865	GO:0006468	IDA	involved_in	protein phosphorylation	22228765	Process
25865	GO:0010595	IMP	involved_in	positive regulation of endothelial cell migration	19001381	Process
25865	GO:0018105	IDA	involved_in	peptidyl-serine phosphorylation	18440775	Process
25865	GO:0018105	IMP	involved_in	peptidyl-serine phosphorylation	28428613	Process
25865	GO:0018107	IMP	involved_in	peptidyl-threonine phosphorylation	28428613	Process
25865	GO:0030949	IMP	involved_in	positive regulation of vascular endothelial growth factor receptor signaling pathway	19001381	Process
25865	GO:0032757	IMP	involved_in	positive regulation of interleukin-8 production	16928771	Process
25865	GO:0032793	IGI	involved_in	positive regulation of CREB transcription factor activity	20497126	Process
25865	GO:0033138	IGI	involved_in	positive regulation of peptidyl-serine phosphorylation	20497126	Process
25865	GO:0035556	IMP	involved_in	intracellular signal transduction	18059339,18440775	Process
25865	GO:0035924	IGI	involved_in	cellular response to vascular endothelial growth factor stimulus	20497126	Process
25865	GO:0035924	IMP	involved_in	cellular response to vascular endothelial growth factor stimulus	18059339,18440775	Process
25865	GO:0038033	IGI	involved_in	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	20497126	Process
25865	GO:0038033	IMP	involved_in	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	18440775	Process
25865	GO:0043536	IGI	involved_in	positive regulation of blood vessel endothelial cell migration	20497126	Process
25865	GO:0043536	IMP	involved_in	positive regulation of blood vessel endothelial cell migration	18440775	Process
25865	GO:0045743	IMP	involved_in	positive regulation of fibroblast growth factor receptor signaling pathway	19001381	Process
25865	GO:0045766	IGI	involved_in	positive regulation of angiogenesis	20497126	Process
25865	GO:0045766	IMP	involved_in	positive regulation of angiogenesis	18440775,19001381	Process
25865	GO:0045785	IMP	involved_in	positive regulation of cell adhesion	17951978	Process
25865	GO:0045944	IDA	involved_in	positive regulation of transcription by RNA polymerase II	17077180	Process
25865	GO:0045944	IMP	involved_in	positive regulation of transcription by RNA polymerase II	18059339	Process
25865	GO:0046777	IDA	involved_in	protein autophosphorylation	17077180	Process
25865	GO:0048010	IMP	involved_in	vascular endothelial growth factor receptor signaling pathway	18059339	Process
25865	GO:0050852	IDA	involved_in	T cell receptor signaling pathway	17077180	Process
25865	GO:0051091	IMP	involved_in	positive regulation of DNA-binding transcription factor activity	19192391	Process
25865	GO:0051092	IMP	involved_in	positive regulation of NF-kappaB transcription factor activity	15604256,16928771,28428613	Process
25865	GO:0070232	IMP	involved_in	regulation of T cell apoptotic process	17077180	Process
25865	GO:0089700	IGI	involved_in	protein kinase D signaling	20497126	Process
25865	GO:1901727	IGI	involved_in	positive regulation of histone deacetylase activity	20497126	Process
25865	GO:1902533	IMP	involved_in	positive regulation of intracellular signal transduction	18440775	Process
25865	GO:2001028	IMP	involved_in	positive regulation of endothelial cell chemotaxis	18440775	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
25865	GO:0004672	IDA	enables	protein kinase activity	17077180	Function
25865	GO:0004674	IDA	enables	protein serine/threonine kinase activity	18440775	Function
25865	GO:0004674	IMP	enables	protein serine/threonine kinase activity	28428613	Function
25865	GO:0005080	IPI	enables	protein kinase C binding	28428613	Function
25865	GO:0005515	IPI	enables	protein binding	17962809,19192391,28514442	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
25865	GO:0005634	IDA	located_in	nucleus	17077180	Component
25865	GO:0005654	IDA	located_in	nucleoplasm		Component
25865	GO:0005737	IDA	located_in	cytoplasm	17077180	Component
25865	GO:0005829	IDA	located_in	cytosol		Component