Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 27339
  • Symbol: PRPF19
  • Description: pre-mRNA processing factor 19

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27339 GO:0000077 IMP involved_in DNA damage checkpoint signaling 24332808 Process
27339 GO:0000209 IDA acts_upstream_of_or_within protein polyubiquitination 11435423 Process
27339 GO:0000244 IDA involved_in spliceosomal tri-snRNP complex assembly 20595234 Process
27339 GO:0000245 IMP involved_in spliceosomal complex assembly 16332694 Process
27339 GO:0000398 IDA involved_in mRNA splicing, via spliceosome 20176811 Process
27339 GO:0006303 IMP involved_in double-strand break repair via nonhomologous end joining 18263876 Process
27339 GO:0008104 IMP involved_in protein localization 18263876 Process
27339 GO:0010498 IMP involved_in proteasomal protein catabolic process 17349974 Process
27339 GO:0070534 IMP involved_in protein K63-linked ubiquitination 20595234,24332808 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27339 GO:0000974 IDA part_of Prp19 complex 20176811 Component
27339 GO:0000974 IPI part_of Prp19 complex 20176811 Component
27339 GO:0005634 IDA located_in nucleus 11435423,19188445 Component
27339 GO:0005681 IPI part_of spliceosomal complex 20176811 Component
27339 GO:0005737 IDA located_in cytoplasm 11435423 Component
27339 GO:0016020 HDA located_in membrane 19946888 Component
27339 GO:0016607 IDA located_in nuclear speck 16332694,24332808 Component
27339 GO:0035861 IDA located_in site of double-strand break 18263876 Component
27339 GO:0071007 IDA part_of U2-type catalytic step 2 spliceosome 28076346 Component
27339 GO:0071013 IDA part_of catalytic step 2 spliceosome 11991638 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27339 GO:0005515 IPI enables protein binding 19188445,19633697,19641227,20176811,20467437,20595234,21536736..... Function
27339 GO:0034450 IDA enables ubiquitin-ubiquitin ligase activity 11435423 Function
27339 GO:0042802 IPI enables identical protein binding 16332694 Function
27339 GO:0061630 IDA enables ubiquitin protein ligase activity 11435423 Function
27339 GO:0061630 IMP enables ubiquitin protein ligase activity 20595234 Function