Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2852
  • Symbol: GPER1
  • Description: G protein-coupled estrogen receptor 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2852 GO:0001934 IDA involved_in positive regulation of protein phosphorylation 20551055,21427217 Process
2852 GO:0002695 IDA involved_in negative regulation of leukocyte activation 23285008 Process
2852 GO:0007186 IMP involved_in G protein-coupled receptor signaling pathway 23840305 Process
2852 GO:0007189 IDA involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway 15539556 Process
2852 GO:0008284 IMP involved_in positive regulation of cell population proliferation 20551055 Process
2852 GO:0010628 IMP involved_in positive regulation of gene expression 23840305 Process
2852 GO:0010629 IMP involved_in negative regulation of gene expression 23840305 Process
2852 GO:0010948 IMP involved_in negative regulation of cell cycle process 23840305 Process
2852 GO:0014068 IDA involved_in positive regulation of phosphatidylinositol 3-kinase signaling 15705806 Process
2852 GO:0030335 IMP involved_in positive regulation of cell migration 20551055 Process
2852 GO:0030518 IDA involved_in intracellular steroid hormone receptor signaling pathway 15705806 Process
2852 GO:0032962 IDA involved_in positive regulation of inositol trisphosphate biosynthetic process 15705806 Process
2852 GO:0043401 IDA involved_in steroid hormone mediated signaling pathway 19931550 Process
2852 GO:0045742 IDA involved_in positive regulation of epidermal growth factor receptor signaling pathway 15705806 Process
2852 GO:0045745 IDA involved_in positive regulation of G protein-coupled receptor signaling pathway 15539556 Process
2852 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 20551055 Process
2852 GO:0050728 IDA involved_in negative regulation of inflammatory response 23285008 Process
2852 GO:0051281 IDA involved_in positive regulation of release of sequestered calcium ion into cytosol 15705806 Process
2852 GO:0051898 IMP involved_in negative regulation of protein kinase B signaling 23840305 Process
2852 GO:0070373 IMP involved_in negative regulation of ERK1 and ERK2 cascade 23840305 Process
2852 GO:0070374 IDA involved_in positive regulation of ERK1 and ERK2 cascade 20551055,21427217 Process
2852 GO:0070474 IDA involved_in positive regulation of uterine smooth muscle contraction 21427217 Process
2852 GO:0071356 IDA involved_in cellular response to tumor necrosis factor 23285008 Process
2852 GO:0071375 IDA involved_in cellular response to peptide hormone stimulus 21427217 Process
2852 GO:0071392 IDA involved_in cellular response to estradiol stimulus 15539556,15705806,19931550,20551055,21149639,21427217,21540189..... Process
2852 GO:1903078 IDA involved_in positive regulation of protein localization to plasma membrane 23674134 Process
2852 GO:1904706 IMP involved_in negative regulation of vascular associated smooth muscle cell proliferation 23840305 Process
2852 GO:2000724 IMP involved_in positive regulation of cardiac vascular smooth muscle cell differentiation 23840305 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2852 GO:0003682 IDA enables chromatin binding 20551055 Function
2852 GO:0005496 IDA enables steroid binding 15539556,15705806 Function
2852 GO:0005515 IPI enables protein binding 20551055,21149639,23674134 Function
2852 GO:0030284 IDA enables nuclear estrogen receptor activity 15539556,15705806 Function
2852 GO:1990239 IDA enables steroid hormone binding 19931550 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2852 GO:0005634 IDA located_in nucleus 20551055,23285008 Component
2852 GO:0005635 IDA located_in nuclear envelope 15705806 Component
2852 GO:0005654 IDA located_in nucleoplasm Component
2852 GO:0005730 IDA located_in nucleolus Component
2852 GO:0005769 IDA located_in early endosome 21540189 Component
2852 GO:0005783 IDA located_in endoplasmic reticulum 15705806,21540189 Component
2852 GO:0005794 IDA located_in Golgi apparatus 15705806 Component
2852 GO:0005802 IDA located_in trans-Golgi network 21540189 Component
2852 GO:0005829 IDA located_in cytosol Component
2852 GO:0005886 IDA NOT located_in plasma membrane 15705806 Component
2852 GO:0005886 IDA located_in plasma membrane 15539556,19931550,21149639,21427217,21540189,23674134..... Component
2852 GO:0030659 IDA located_in cytoplasmic vesicle membrane 21540189 Component
2852 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component
2852 GO:0045095 IDA located_in keratin filament 21149639 Component
2852 GO:0048471 IDA located_in perinuclear region of cytoplasm 21540189 Component
2852 GO:0055037 IDA located_in recycling endosome 21540189 Component