Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 31746
  • Symbol: Traf6
  • Description: TNF-receptor-associated factor 6

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
31746 GO:0005515 IPI enables protein binding 10465784,12176339 Function
31746 GO:0032813 IDA enables tumor necrosis factor receptor superfamily binding 12894227,25874673 Function
31746 GO:0061630 IMP enables ubiquitin protein ligase activity 30879902 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
31746 GO:0010508 IMP involved_in positive regulation of autophagy 24374193 Process
31746 GO:0033209 IGI involved_in tumor necrosis factor-mediated signaling pathway 12176339,17765686,25874673 Process
31746 GO:0033209 IMP involved_in tumor necrosis factor-mediated signaling pathway 24162658 Process
31746 GO:0043068 IGI acts_upstream_of positive regulation of programmed cell death 12176339,17765686,25874673 Process
31746 GO:0043068 IMP acts_upstream_of positive regulation of programmed cell death 24162658 Process
31746 GO:0043122 IMP involved_in regulation of I-kappaB kinase/NF-kappaB signaling 14585960 Process
31746 GO:0045087 IMP involved_in innate immune response 14585960 Process
31746 GO:0045746 IGI involved_in negative regulation of Notch signaling pathway 25280943 Process
31746 GO:0045746 IPI involved_in negative regulation of Notch signaling pathway 25280943 Process
31746 GO:0045752 IDA involved_in positive regulation of Toll signaling pathway 11447260 Process
31746 GO:0045752 IGI involved_in positive regulation of Toll signaling pathway 11447260 Process
31746 GO:0046330 IGI involved_in positive regulation of JNK cascade 23726905 Process
31746 GO:0046330 IMP involved_in positive regulation of JNK cascade 17765686 Process
31746 GO:0050688 IMP involved_in regulation of defense response to virus 24374193 Process
31746 GO:0050829 IMP NOT involved_in defense response to Gram-negative bacterium 16894030 Process
31746 GO:0061059 IMP involved_in positive regulation of peptidoglycan recognition protein signaling pathway 30879902 Process
31746 GO:0070534 IMP involved_in protein K63-linked ubiquitination 30879902 Process
31746 GO:1903265 IGI involved_in positive regulation of tumor necrosis factor-mediated signaling pathway 23726905 Process