Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 37455
  • Symbol: Egfr
  • Description: Epidermal growth factor receptor

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
37455 GO:0001654 IMP involved_in eye development 14536058 Process
37455 GO:0001742 IMP involved_in oenocyte differentiation 28715417 Process
37455 GO:0001751 IMP involved_in compound eye photoreceptor cell differentiation 16377567 Process
37455 GO:0002009 IMP involved_in morphogenesis of an epithelium 9927461 Process
37455 GO:0003015 IMP involved_in heart process 20523889 Process
37455 GO:0007173 IDA involved_in epidermal growth factor receptor signaling pathway 7601354,7651519,8565833,9531530,10652272,10688656 Process
37455 GO:0007173 IGI involved_in epidermal growth factor receptor signaling pathway 8162856,8978043 Process
37455 GO:0007173 IMP involved_in epidermal growth factor receptor signaling pathway 9729495,9806926,10089881,11141565,11245584,16326394,22242005,3..... Process
37455 GO:0007298 IGI involved_in border follicle cell migration 23525006 Process
37455 GO:0007298 IMP involved_in border follicle cell migration 11141565 Process
37455 GO:0007309 IMP involved_in oocyte axis specification 16908845 Process
37455 GO:0007367 IMP involved_in segment polarity determination 15930099 Process
37455 GO:0007390 IMP involved_in germ-band shortening 8946251,9927461 Process
37455 GO:0007391 IMP involved_in dorsal closure 9927461,23579691,28628612 Process
37455 GO:0007395 IMP involved_in dorsal closure, spreading of leading edge cells 28628612 Process
37455 GO:0007422 IMP involved_in peripheral nervous system development 12967983 Process
37455 GO:0007426 IMP involved_in tracheal outgrowth, open tracheal system 16326394 Process
37455 GO:0007431 IMP involved_in salivary gland development 9927461 Process
37455 GO:0007443 IMP involved_in Malpighian tubule morphogenesis 9927461 Process
37455 GO:0007444 IMP involved_in imaginal disc development 10934021 Process
37455 GO:0007455 IMP involved_in eye-antennal disc morphogenesis 16963016 Process
37455 GO:0007472 IMP involved_in wing disc morphogenesis 12930782 Process
37455 GO:0007474 IMP involved_in imaginal disc-derived wing vein specification 10331978,23549788 Process
37455 GO:0007476 IMP involved_in imaginal disc-derived wing morphogenesis 10995384,12930782,14536058,16648592 Process
37455 GO:0007477 IMP involved_in notum development 10995384 Process
37455 GO:0007479 IMP involved_in leg disc proximal/distal pattern formation 12181568,15965980 Process
37455 GO:0007482 IMP involved_in haltere development 16815386 Process
37455 GO:0008071 IMP involved_in maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded 3107840 Process
37455 GO:0008284 IMP involved_in positive regulation of cell population proliferation 19141677,21176204 Process
37455 GO:0008340 IMP involved_in determination of adult lifespan 21516106 Process
37455 GO:0008355 IMP involved_in olfactory learning 23512935 Process
37455 GO:0008406 IMP involved_in gonad development 21377458 Process
37455 GO:0008586 IMP involved_in imaginal disc-derived wing vein morphogenesis 15766758 Process
37455 GO:0009792 IMP involved_in embryo development ending in birth or egg hatching 8070664 Process
37455 GO:0009880 IGI involved_in embryonic pattern specification 17898168 Process
37455 GO:0010628 IMP acts_upstream_of positive regulation of gene expression 9806926 Process
37455 GO:0010628 IMP involved_in positive regulation of gene expression 28628612 Process
37455 GO:0010629 IMP involved_in negative regulation of gene expression 28628612 Process
37455 GO:0016318 IMP involved_in ommatidial rotation 14507782 Process
37455 GO:0016330 IMP involved_in second mitotic wave involved in compound eye morphogenesis 11257224 Process
37455 GO:0016333 IMP involved_in morphogenesis of follicular epithelium 9504923 Process
37455 GO:0022008 IGI involved_in neurogenesis 17898168 Process
37455 GO:0030031 IMP involved_in cell projection assembly 12198500 Process
37455 GO:0030381 IGI involved_in chorion-containing eggshell pattern formation 11606538 Process
37455 GO:0030718 IGI involved_in germ-line stem cell population maintenance 16399083 Process
37455 GO:0035088 IMP involved_in establishment or maintenance of apical/basal cell polarity 16908845 Process
37455 GO:0035149 IGI involved_in lumen formation, open tracheal system 23029159 Process
37455 GO:0035159 IMP involved_in regulation of tube length, open tracheal system 28678789 Process
37455 GO:0035160 IMP involved_in maintenance of epithelial integrity, open tracheal system 16831830 Process
37455 GO:0035225 IMP involved_in determination of genital disc primordium 15893978 Process
37455 GO:0035277 IMP involved_in spiracle morphogenesis, open tracheal system 15930099 Process
37455 GO:0035309 IMP involved_in wing and notum subfield formation 10860999 Process
37455 GO:0035310 IMP involved_in notum cell fate specification 10995384 Process
37455 GO:0042327 IMP involved_in positive regulation of phosphorylation 28628612 Process
37455 GO:0042675 IMP involved_in compound eye cone cell differentiation 8929534 Process
37455 GO:0043066 IMP involved_in negative regulation of apoptotic process 16326394,17055987,23579691 Process
37455 GO:0043703 IMP involved_in photoreceptor cell fate determination 7833286,8929534 Process
37455 GO:0045198 IMP involved_in establishment of epithelial cell apical/basal polarity 25437306 Process
37455 GO:0045465 IMP involved_in R8 cell differentiation 9806926 Process
37455 GO:0045572 IMP involved_in positive regulation of imaginal disc growth 29719260 Process
37455 GO:0046530 IMP involved_in photoreceptor cell differentiation 11245584 Process
37455 GO:0046673 IMP involved_in negative regulation of compound eye retinal cell programmed cell death 15511643 Process
37455 GO:0046843 IMP involved_in dorsal appendage formation 17008069 Process
37455 GO:0048149 IMP involved_in behavioral response to ethanol 19464045 Process
37455 GO:0048546 IMP involved_in digestive tract morphogenesis 21176204 Process
37455 GO:0048749 IMP involved_in compound eye development 1634999,11301250,14507785 Process
37455 GO:0048865 IMP involved_in stem cell fate commitment 20463031 Process
37455 GO:0051781 IMP involved_in positive regulation of cell division 16326394 Process
37455 GO:0061331 IMP involved_in epithelial cell proliferation involved in Malpighian tubule morphogenesis 9637680,11861476 Process
37455 GO:0070374 IDA acts_upstream_of positive regulation of ERK1 and ERK2 cascade 9531530 Process
37455 GO:0090303 IMP involved_in positive regulation of wound healing 22140578 Process
37455 GO:1903688 IGI involved_in positive regulation of border follicle cell migration 16054027,16712835 Process
37455 GO:2000134 IMP involved_in negative regulation of G1/S transition of mitotic cell cycle 15809036 Process
37455 GO:2001234 IGI involved_in negative regulation of apoptotic signaling pathway 9814703,30379844 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
37455 GO:0005006 IDA enables epidermal growth factor receptor activity 7601354,7651519,9531530,10688656,11782411 Function
37455 GO:0005515 IPI enables protein binding 7601354,12835389,12900463,21340027,28993397 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
37455 GO:0005886 HDA located_in plasma membrane 19317464 Component
37455 GO:0005886 IDA located_in plasma membrane 10089881,16054027 Component
37455 GO:0016324 IDA is_active_in apical plasma membrane 34411095 Component
37455 GO:0035230 IDA colocalizes_with cytoneme 21493861 Component