Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 42549
  • Symbol: InR
  • Description: Insulin-like receptor

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42549 GO:0001700 IEP involved_in embryonic development via the syncytial blastoderm 2454394,3934169 Process
42549 GO:0002052 IGI involved_in positive regulation of neuroblast proliferation 30245208 Process
42549 GO:0006468 IMP involved_in protein phosphorylation 8603594 Process
42549 GO:0006979 IMP involved_in response to oxidative stress 17895391 Process
42549 GO:0007285 IMP involved_in primary spermatocyte growth 19384053 Process
42549 GO:0007390 IGI involved_in germ-band shortening 10491260 Process
42549 GO:0007399 IMP involved_in nervous system development 7628438 Process
42549 GO:0007411 IMP involved_in axon guidance 12702880 Process
42549 GO:0007424 HMP involved_in open tracheal system development 21750678 Process
42549 GO:0007446 IMP involved_in imaginal disc growth 8603594 Process
42549 GO:0007623 IMP involved_in circadian rhythm 17895391 Process
42549 GO:0007626 IMP involved_in locomotory behavior 17264888 Process
42549 GO:0008284 IMP involved_in positive regulation of cell population proliferation 8603594,11250149 Process
42549 GO:0008286 IDA involved_in insulin receptor signaling pathway 3934169,7711018,21707536,29491510 Process
42549 GO:0008286 IGI involved_in insulin receptor signaling pathway 33744321 Process
42549 GO:0008286 IMP involved_in insulin receptor signaling pathway 7628438,11832249,22242005,27525480,29950391 Process
42549 GO:0008340 IMP involved_in determination of adult lifespan 11292875,19692410 Process
42549 GO:0008585 IMP involved_in female gonad development 23022298 Process
42549 GO:0009267 IMP involved_in cellular response to starvation 25472843 Process
42549 GO:0009792 IEP involved_in embryo development ending in birth or egg hatching 2454394 Process
42549 GO:0010507 IMP involved_in negative regulation of autophagy 19066463 Process
42549 GO:0010884 IMP involved_in positive regulation of lipid storage 11832249,19822665 Process
42549 GO:0014068 IMP involved_in positive regulation of phosphatidylinositol 3-kinase signaling 11832249,18412985,23935447 Process
42549 GO:0030307 IMP involved_in positive regulation of cell growth 11250149,19910925,29514084,33744321 Process
42549 GO:0030707 IMP involved_in follicle cell of egg chamber development 26205122 Process
42549 GO:0033500 IMP involved_in carbohydrate homeostasis 21464442 Process
42549 GO:0034059 IDA involved_in response to anoxia 19412543 Process
42549 GO:0035264 IMP involved_in multicellular organism growth 21464442 Process
42549 GO:0036099 IMP involved_in female germ-line stem cell population maintenance 29549109 Process
42549 GO:0036335 IGI involved_in intestinal stem cell homeostasis 25367037 Process
42549 GO:0040014 IMP involved_in regulation of multicellular organism growth 8603594,16086608,16182527 Process
42549 GO:0040018 IMP involved_in positive regulation of multicellular organism growth 8603594,11250149 Process
42549 GO:0042078 IMP involved_in germ-line stem cell division 29549109 Process
42549 GO:0042127 IMP involved_in regulation of cell population proliferation 8603594 Process
42549 GO:0042220 IGI involved_in response to cocaine 16730347 Process
42549 GO:0042321 IMP involved_in negative regulation of circadian sleep/wake cycle, sleep 24690889 Process
42549 GO:0042593 IMP involved_in glucose homeostasis 22242005,25472843 Process
42549 GO:0042632 IMP involved_in cholesterol homeostasis 27326933 Process
42549 GO:0045793 IMP involved_in positive regulation of cell size 11250149 Process
42549 GO:0046620 IMP involved_in regulation of organ growth 16086608 Process
42549 GO:0046622 IGI involved_in positive regulation of organ growth 11752451 Process
42549 GO:0046622 IMP involved_in positive regulation of organ growth 11250149 Process
42549 GO:0046777 IMP involved_in protein autophosphorylation 12702880 Process
42549 GO:0048132 IMP involved_in female germ-line stem cell asymmetric division 19336466 Process
42549 GO:0048133 IMP involved_in male germ-line stem cell asymmetric division 19384053 Process
42549 GO:0048542 IMP involved_in lymph gland development 22510984 Process
42549 GO:0048589 IMP involved_in developmental growth 16086608 Process
42549 GO:0055088 IMP involved_in lipid homeostasis 11832249,21464442 Process
42549 GO:0060180 IMP involved_in female mating behavior 20739318 Process
42549 GO:0060250 IMP involved_in germ-line stem-cell niche homeostasis 19136634,29549109 Process
42549 GO:0061964 IMP involved_in negative regulation of entry into reproductive diapause 27689881 Process
42549 GO:0070328 IMP involved_in triglyceride homeostasis 25472843 Process
42549 GO:0070346 IMP involved_in positive regulation of fat cell proliferation 19822665 Process
42549 GO:0090278 IMP involved_in negative regulation of peptide hormone secretion 25101872 Process
42549 GO:0090303 IMP involved_in positive regulation of wound healing 27713427 Process
42549 GO:1903688 IMP involved_in positive regulation of border follicle cell migration 29950391 Process
42549 GO:1904801 IMP involved_in positive regulation of neuron remodeling 24068890 Process
42549 GO:2000252 IMP involved_in negative regulation of feeding behavior 11832249,22876196 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42549 GO:0004713 IDA enables protein tyrosine kinase activity 10455177 Function
42549 GO:0004713 IMP enables protein tyrosine kinase activity 8603594 Function
42549 GO:0005009 IDA enables insulin receptor activity 3014506,3934169,7628438,29491510 Function
42549 GO:0005009 IMP enables insulin receptor activity 12702880 Function
42549 GO:0005515 IPI enables protein binding 10455177,31784462 Function
42549 GO:0043559 IPI enables insulin binding 20974844,29491510 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42549 GO:0005886 IDA located_in plasma membrane 7628438 Component
42549 GO:0005899 IDA part_of insulin receptor complex 3934169,7628438 Component