Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 42871
  • Symbol: Apc2
  • Description: Adenomatous polyposis coli 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42871 GO:0000281 IMP involved_in mitotic cytokinesis 11206549 Process
42871 GO:0007155 IMP involved_in cell adhesion 11862214 Process
42871 GO:0007367 IMP involved_in segment polarity determination 26446838 Process
42871 GO:0007399 IDA involved_in nervous system development 10491393 Process
42871 GO:0007405 IGI involved_in neuroblast proliferation 12297097 Process
42871 GO:0007420 IGI involved_in brain development 12297097 Process
42871 GO:0007447 IGI involved_in imaginal disc pattern formation 12297098 Process
42871 GO:0008362 IMP involved_in chitin-based embryonic cuticle biosynthetic process 16720878 Process
42871 GO:0009968 IMP involved_in negative regulation of signal transduction 10491393 Process
42871 GO:0030589 IMP involved_in pseudocleavage involved in syncytial blastoderm formation 19279137,21486956 Process
42871 GO:0030707 IGI involved_in follicle cell of egg chamber development 29093440 Process
42871 GO:0030720 IGI involved_in oocyte localization involved in germarium-derived egg chamber formation 11862214 Process
42871 GO:0030720 IMP involved_in oocyte localization involved in germarium-derived egg chamber formation 11862214 Process
42871 GO:0030866 IMP involved_in cortical actin cytoskeleton organization 21486956 Process
42871 GO:0030951 IMP involved_in establishment or maintenance of microtubule cytoskeleton polarity 21145742 Process
42871 GO:0032436 IMP involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process 21471006 Process
42871 GO:0035190 IMP involved_in syncytial nuclear migration 16720878 Process
42871 GO:0035293 IGI involved_in chitin-based larval cuticle pattern formation 11923210,12297098,21471006 Process
42871 GO:0035293 IMP involved_in chitin-based larval cuticle pattern formation 11923210 Process
42871 GO:0090090 IDA involved_in negative regulation of canonical Wnt signaling pathway 31189665 Process
42871 GO:0090090 IGI involved_in negative regulation of canonical Wnt signaling pathway 10491393,11923210,12297098,17367777,21471006,22174073,22645652..... Process
42871 GO:0090090 IMP involved_in negative regulation of canonical Wnt signaling pathway 11923210,22359584,24931405,26393419,26446838,27068743..... Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42871 GO:0005515 IPI enables protein binding 19279137 Function
42871 GO:0008013 IMP enables beta-catenin binding 21471006 Function
42871 GO:0008013 IPI enables beta-catenin binding 10491393,19279137 Function
42871 GO:0060090 IMP enables molecular adaptor activity 22645652 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42871 GO:0005737 IDA located_in cytoplasm 11923210,21471006,24257623 Component
42871 GO:0005829 IDA located_in cytosol 31189665 Component
42871 GO:0005884 IDA colocalizes_with actin filament 19279137 Component
42871 GO:0005938 IDA located_in cell cortex 11923210,12297097,16720878,24257623 Component
42871 GO:0030425 IDA located_in dendrite 17470283 Component
42871 GO:0030877 IDA part_of beta-catenin destruction complex 22645652,31189665,32129710 Component
42871 GO:0030877 IGI part_of beta-catenin destruction complex 22174073 Component
42871 GO:0030877 IMP part_of beta-catenin destruction complex 26446838 Component
42871 GO:0032154 IDA located_in cleavage furrow 12297097 Component
42871 GO:0032991 IPI part_of protein-containing complex 19279137 Component
42871 GO:0043025 IDA located_in neuronal cell body 17470283 Component
42871 GO:0045179 IDA located_in apical cortex 12297098 Component
42871 GO:0045180 IDA located_in basal cortex 24257623 Component