Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4294
• Symbol: MAP3K10
• Description: mitogen-activated protein kinase kinase kinase 10

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4294	GO:0004674	IDA	enables	protein serine/threonine kinase activity	19801649	Function
4294	GO:0005515	IPI	enables	protein binding	20936779,32707033	Function
4294	GO:0043425	IPI	enables	bHLH transcription factor binding	19801649	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4294	GO:0005737	IDA	located_in	cytoplasm	18455992	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4294	GO:0007224	IMP	involved_in	smoothened signaling pathway	18455992	Process
4294	GO:0018105	IDA	involved_in	peptidyl-serine phosphorylation	19801649	Process
4294	GO:0018107	IDA	involved_in	peptidyl-threonine phosphorylation	19801649	Process
4294	GO:0043433	IMP	involved_in	negative regulation of DNA-binding transcription factor activity	19801649	Process
4294	GO:0043507	IMP	involved_in	positive regulation of JUN kinase activity	17584736	Process
4294	GO:0045892	IMP	involved_in	negative regulation of DNA-templated transcription	19801649	Process
4294	GO:0046330	IMP	involved_in	positive regulation of JNK cascade	17584736	Process