Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 4751
  • Symbol: NEK2
  • Description: NIMA related kinase 2

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4751 GO:0000776 IDA colocalizes_with kinetochore 17621308 Component
4751 GO:0000776 IDA located_in kinetochore 14978040 Component
4751 GO:0005654 IDA located_in nucleoplasm Component
4751 GO:0005813 IDA located_in centrosome 21399614,26220856 Component
4751 GO:0032991 IMP part_of protein-containing complex 10880350 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4751 GO:0004672 IDA enables protein kinase activity 10880350,18086858,26220856 Function
4751 GO:0004672 IMP enables protein kinase activity 24554434 Function
4751 GO:0005515 IPI enables protein binding 9647649,10880350,14978040,15161910,16648845,17621308,18086858,..... Function
4751 GO:0019903 IPI enables protein phosphatase binding 10880350 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4751 GO:0006468 IDA involved_in protein phosphorylation 21076410 Process
4751 GO:0006468 IMP involved_in protein phosphorylation 24554434 Process
4751 GO:0007059 IDA involved_in chromosome segregation 14978040 Process
4751 GO:0032212 IMP involved_in positive regulation of telomere maintenance via telomerase 21531765 Process
4751 GO:0046602 IMP involved_in regulation of mitotic centrosome separation 26220856 Process
4751 GO:0046777 IDA involved_in protein autophosphorylation 17626005 Process
4751 GO:0046777 IMP involved_in protein autophosphorylation 10880350 Process
4751 GO:0051299 IDA involved_in centrosome separation 18086858 Process
4751 GO:0051973 IMP involved_in positive regulation of telomerase activity 21531765 Process
4751 GO:0051988 IMP involved_in regulation of attachment of spindle microtubules to kinetochore 18297113 Process
4751 GO:1903126 IMP involved_in negative regulation of centriole-centriole cohesion 24554434 Process
4751 GO:1904355 IMP involved_in positive regulation of telomere capping 21531765 Process