Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 50754
• Symbol: Fbxw7
• Description: F-box and WD-40 domain protein 7

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
50754	GO:0001570	IMP	acts_upstream_of_or_within	vasculogenesis	21503901	Process
50754	GO:0007219	IDA	acts_upstream_of_or_within	Notch signaling pathway	11425854	Process
50754	GO:0030324	IMP	acts_upstream_of_or_within	lung development	21503901	Process
50754	GO:0031146	IDA	involved_in	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	21953459	Process
50754	GO:0031648	IDA	acts_upstream_of_or_within	protein destabilization		Process
50754	GO:0042752	IMP	involved_in	regulation of circadian rhythm	27238018	Process
50754	GO:0090049	IMP	involved_in	regulation of cell migration involved in sprouting angiogenesis	23507969	Process
50754	GO:1901800	IMP	involved_in	positive regulation of proteasomal protein catabolic process	23858059	Process
50754	GO:1903026	IDA	acts_upstream_of_or_within	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding		Process
50754	GO:1903378	IMP	involved_in	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	23858059	Process
50754	GO:2000060	IMP	involved_in	positive regulation of ubiquitin-dependent protein catabolic process	27238018	Process
50754	GO:2001205	IMP	involved_in	negative regulation of osteoclast development	29149593	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
50754	GO:0005515	IPI	enables	protein binding	11425854,21953459,23858059	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
50754	GO:0005634	IDA	NOT located_in	nucleus	11735228	Component
50754	GO:0005634	IDA	located_in	nucleus	20208556	Component
50754	GO:0005730	IDA	located_in	nucleolus		Component
50754	GO:0005739	IDA	located_in	mitochondrion	23858059	Component
50754	GO:0005783	IDA	located_in	endoplasmic reticulum	11735228	Component
50754	GO:0005794	IDA	located_in	Golgi apparatus	11735228	Component
50754	GO:0048471	IDA	located_in	perinuclear region of cytoplasm	20208556	Component