Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 53373
• Symbol: TPCN1
• Description: two pore segment channel 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
53373	GO:0005248	IDA	enables	voltage-gated sodium channel activity	24776928	Function
53373	GO:0005515	IPI	enables	protein binding	15094197,21903581,24188827	Function
53373	GO:0015280	IDA	enables	ligand-gated sodium channel activity	23063126,24776928	Function
53373	GO:0042802	IPI	enables	identical protein binding	21903581	Function
53373	GO:0072345	IDA	NOT enables	NAADP-sensitive calcium-release channel activity	24776928	Function
53373	GO:0072345	IDA	enables	NAADP-sensitive calcium-release channel activity	19620632	Function
53373	GO:0097682	IDA	enables	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity	23063126,24776928	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
53373	GO:0005765	IDA	located_in	lysosomal membrane	19620632,23063126	Component
53373	GO:0010008	IDA	located_in	endosome membrane	19620632,23063126	Component
53373	GO:0036019	IDA	located_in	endolysosome	24776928	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
53373	GO:0010508	IDA	involved_in	positive regulation of autophagy	22012985	Process
53373	GO:0075509	IMP	involved_in	endocytosis involved in viral entry into host cell	25722412	Process