Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 55159
  • Symbol: RFWD3
  • Description: ring finger and WD repeat domain 3

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
55159 GO:0000724 IDA involved_in double-strand break repair via homologous recombination 26474068,28575657,28575658 Process
55159 GO:0000724 IMP involved_in double-strand break repair via homologous recombination 28691929 Process
55159 GO:0006974 IDA involved_in DNA damage response 26474068,28575657,28575658 Process
55159 GO:0010212 IDA involved_in response to ionizing radiation 20173098 Process
55159 GO:0016567 IDA involved_in protein ubiquitination 20173098,26474068,28575657,28575658 Process
55159 GO:0031297 IDA involved_in replication fork processing 26474068 Process
55159 GO:0031571 IMP involved_in mitotic G1 DNA damage checkpoint signaling 20173098 Process
55159 GO:0036297 IMP involved_in interstrand cross-link repair 28575657,28575658 Process
55159 GO:2000001 IMP involved_in regulation of DNA damage checkpoint 21504906 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
55159 GO:0002039 IPI enables p53 binding 20173098 Function
55159 GO:0005515 IPI enables protein binding 19549727,20173098,21504906,24126761,25260751,28575657,28575658..... Function
55159 GO:0061630 IDA enables ubiquitin protein ligase activity 20173098,26474068,28575657,28575658 Function
55159 GO:0097371 IPI enables MDM2/MDM4 family protein binding 20173098 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
55159 GO:0005634 IDA located_in nucleus 20173098 Component
55159 GO:0005634 IMP located_in nucleus 28691929 Component
55159 GO:0005654 IDA located_in nucleoplasm Component
55159 GO:0035861 IDA colocalizes_with site of double-strand break 21504906 Component
55159 GO:0090734 IDA located_in site of DNA damage 28575657,28575658 Component