Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 5578
  • Symbol: PRKCA
  • Description: protein kinase C alpha

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5578 GO:0001938 IMP involved_in positive regulation of endothelial cell proliferation 11909826 Process
5578 GO:0002159 IMP involved_in desmosome assembly 18474624 Process
5578 GO:0006468 IDA involved_in protein phosphorylation 10770950 Process
5578 GO:0010595 IMP involved_in positive regulation of endothelial cell migration 11909826 Process
5578 GO:0030335 IMP involved_in positive regulation of cell migration 23990668 Process
5578 GO:0031666 IMP involved_in positive regulation of lipopolysaccharide-mediated signaling pathway 9830023 Process
5578 GO:0034351 IMP involved_in negative regulation of glial cell apoptotic process 9927633 Process
5578 GO:0043536 IDA involved_in positive regulation of blood vessel endothelial cell migration 20011604 Process
5578 GO:0043687 IDA involved_in post-translational protein modification 20228790 Process
5578 GO:0045766 IMP involved_in positive regulation of angiogenesis 11909826 Process
5578 GO:0045785 IMP involved_in positive regulation of cell adhesion 11909826 Process
5578 GO:0045931 IMP involved_in positive regulation of mitotic cell cycle 10848585 Process
5578 GO:0070555 IMP involved_in response to interleukin-1 19281832 Process
5578 GO:0090330 IDA involved_in regulation of platelet aggregation 12724315 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5578 GO:0004672 IDA enables protein kinase activity 10770950 Function
5578 GO:0004697 EXP enables protein kinase C activity 7520444,7539802,12391145,17392515 Function
5578 GO:0004697 IDA enables protein kinase C activity 25313067 Function
5578 GO:0004698 IMP enables calcium-dependent protein kinase C activity 33934390 Function
5578 GO:0005515 IPI enables protein binding 12571249,12893243,16810323,17244820,18566587,21703451,21952047..... Function
5578 GO:0019899 IDA enables enzyme binding 18556656 Function
5578 GO:0035403 IDA enables histone H3T6 kinase activity 20228790 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5578 GO:0005737 IDA located_in cytoplasm 15632189,23990668 Component
5578 GO:0005739 HDA located_in mitochondrion 20833797 Component
5578 GO:0005783 IDA located_in endoplasmic reticulum 18556656 Component
5578 GO:0005829 IDA located_in cytosol 17983652 Component
5578 GO:0005886 IDA located_in plasma membrane 15632189,23990668 Component
5578 GO:0036064 IDA is_active_in ciliary basal body 33934390 Component
5578 GO:0070062 HDA located_in extracellular exosome 19056867 Component