Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 56532
  • Symbol: Ripk3
  • Description: receptor-interacting serine-threonine kinase 3

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56532 GO:0001914 IGI involved_in regulation of T cell mediated cytotoxicity 21876153 Process
56532 GO:0002819 IGI involved_in regulation of adaptive immune response 21876153 Process
56532 GO:0006476 IGI acts_upstream_of protein deacetylation Process
56532 GO:0007249 IDA acts_upstream_of_or_within I-kappaB kinase/NF-kappaB signaling 10490590 Process
56532 GO:0032649 IGI involved_in regulation of type II interferon production 21876153 Process
56532 GO:0033077 IGI involved_in T cell differentiation in thymus 21876153 Process
56532 GO:0042981 IDA involved_in regulation of apoptotic process 32200799 Process
56532 GO:0042981 IMP involved_in regulation of apoptotic process 27321907,27746097,27917412 Process
56532 GO:0043029 IGI involved_in T cell homeostasis 21876153 Process
56532 GO:0046006 IGI involved_in regulation of activated T cell proliferation 21876153 Process
56532 GO:0048535 IGI involved_in lymph node development 21876153 Process
56532 GO:0048536 IGI involved_in spleen development 21876153 Process
56532 GO:0048538 IGI involved_in thymus development 21876153 Process
56532 GO:0051347 IGI acts_upstream_of_or_within positive regulation of transferase activity 19498109 Process
56532 GO:0051351 IDA acts_upstream_of_or_within positive regulation of ligase activity 19498109 Process
56532 GO:0051353 IDA acts_upstream_of_or_within positive regulation of oxidoreductase activity 19498109 Process
56532 GO:0051607 IDA involved_in defense response to virus 22423968,30635240,32200799,32296175 Process
56532 GO:0051607 IMP involved_in defense response to virus 27321907,27746097,27917412 Process
56532 GO:0060545 IDA involved_in positive regulation of necroptotic process 22423968,32200799,32296175 Process
56532 GO:0060545 IMP involved_in positive regulation of necroptotic process 21052097,22265414,24813849,24813850,27321907 Process
56532 GO:0070235 IGI involved_in regulation of activation-induced cell death of T cells 21876153 Process
56532 GO:0070266 IGI acts_upstream_of_or_within necroptotic process 19498109,21368763,21402742,22037414,22675671 Process
56532 GO:0070266 IMP involved_in necroptotic process 24012422 Process
56532 GO:0070301 IMP involved_in cellular response to hydrogen peroxide 27258785 Process
56532 GO:0072593 IMP acts_upstream_of reactive oxygen species metabolic process 19498109 Process
56532 GO:0090312 IGI acts_upstream_of_or_within positive regulation of protein deacetylation Process
56532 GO:0097300 IMP involved_in programmed necrotic cell death 27258785 Process
56532 GO:0097528 IMP involved_in execution phase of necroptosis 27746097,27917412 Process
56532 GO:2000377 IMP acts_upstream_of_or_within regulation of reactive oxygen species metabolic process 21052097 Process
56532 GO:2000379 IMP acts_upstream_of_or_within positive regulation of reactive oxygen species metabolic process 19498109 Process
56532 GO:2000379 IMP involved_in positive regulation of reactive oxygen species metabolic process 21052097 Process
56532 GO:2000452 IGI involved_in regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation 21876153 Process
56532 GO:2001244 IDA acts_upstream_of_or_within positive regulation of intrinsic apoptotic signaling pathway 10490590 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56532 GO:0004672 IDA enables protein kinase activity 10490590 Function
56532 GO:0004674 IDA enables protein serine/threonine kinase activity 24012422,24095729,32200799,32296175 Function
56532 GO:0004704 IDA enables NF-kappaB-inducing kinase activity 10490590 Function
56532 GO:0005515 IPI enables protein binding 19498109,19524513,21052097,21368763,22265413,22423968,22922364..... Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56532 GO:0005622 IDA located_in intracellular anatomical structure 10490590 Component
56532 GO:0005634 IDA located_in nucleus 28607035,32200799,32296175 Component
56532 GO:0005737 IDA located_in cytoplasm 28607035,32200799,32296175 Component