Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 64444
  • Symbol: Isl1
  • Description: ISL LIM homeobox 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
64444 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 19619559 Function
64444 GO:0001046 IDA enables core promoter sequence-specific DNA binding 11043578 Function
64444 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 19619559 Function
64444 GO:0005515 IPI enables protein binding 9315627 Function
64444 GO:0016922 IDA enables nuclear receptor binding 11043578 Function
64444 GO:0016922 IPI enables nuclear receptor binding 11043578 Function
64444 GO:0030274 IMP enables LIM domain binding 26260513 Function
64444 GO:0030331 IDA enables nuclear estrogen receptor binding 11043578 Function
64444 GO:0043565 IDA enables sequence-specific DNA binding 1691825,7759514,9514122 Function
64444 GO:1990837 IDA enables sequence-specific double-stranded DNA binding 18539116 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
64444 GO:0005634 IDA located_in nucleus 11043578 Component
64444 GO:0005667 IDA part_of transcription regulator complex 18539116 Component
64444 GO:0005737 IDA located_in cytoplasm 30341898 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
64444 GO:0006355 IDA involved_in regulation of DNA-templated transcription 7759514 Process
64444 GO:0010718 IMP involved_in positive regulation of epithelial to mesenchymal transition 23270756 Process
64444 GO:0031103 IEP involved_in axon regeneration 10363827 Process
64444 GO:0031333 IDA involved_in negative regulation of protein-containing complex assembly 11043578 Process
64444 GO:0032024 IMP involved_in positive regulation of insulin secretion 11978636,29678908 Process
64444 GO:0033138 IMP involved_in positive regulation of peptidyl-serine phosphorylation 29678908 Process
64444 GO:0033147 IDA involved_in negative regulation of intracellular estrogen receptor signaling pathway 11043578 Process
64444 GO:0045880 IDA involved_in positive regulation of smoothened signaling pathway 32544883 Process
64444 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 16613990,19619559 Process
64444 GO:0045944 IGI involved_in positive regulation of transcription by RNA polymerase II 18539116 Process
64444 GO:0050680 IMP involved_in negative regulation of epithelial cell proliferation 23270756 Process
64444 GO:0071385 IEP involved_in cellular response to glucocorticoid stimulus 19619559 Process
64444 GO:0071560 IEP involved_in cellular response to transforming growth factor beta stimulus 23270756 Process
64444 GO:0072201 IMP involved_in negative regulation of mesenchymal cell proliferation 23270756 Process
64444 GO:0090280 IMP involved_in positive regulation of calcium ion import 29678908 Process
64444 GO:2000676 IMP involved_in positive regulation of type B pancreatic cell apoptotic process 30341898 Process