Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 65125
  • Symbol: WNK1
  • Description: WNK lysine deficient protein kinase 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
65125 GO:0004672 IMP enables protein kinase activity 16669787 Function
65125 GO:0004674 IDA enables protein serine/threonine kinase activity 10660600,15883153,16263722,16832045,17190791,19665974,19739668..... Function
65125 GO:0005515 IPI enables protein binding 15350218,16832045,17721439,19389623,33964204,35044719..... Function
65125 GO:0005524 IDA enables ATP binding 10660600 Function
65125 GO:0019901 IPI enables protein kinase binding 16669787 Function
65125 GO:0019902 IDA enables phosphatase binding 19389623 Function
65125 GO:0030295 IMP enables protein kinase activator activity 16669787 Function
65125 GO:0140693 IDA enables molecular condensate scaffold activity 36318922 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
65125 GO:0005634 IDA is_active_in nucleus 29196535 Component
65125 GO:0005737 IDA located_in cytoplasm 10660600 Component
65125 GO:0005829 IDA is_active_in cytosol 17190791 Component
65125 GO:0005829 IDA located_in cytosol Component
65125 GO:0043232 IDA is_active_in intracellular non-membrane-bounded organelle 36318922 Component
65125 GO:0072686 IDA is_active_in mitotic spindle 21220314 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
65125 GO:0006468 IDA involved_in protein phosphorylation 10660600 Process
65125 GO:0006468 IMP involved_in protein phosphorylation 16669787 Process
65125 GO:0006884 IDA involved_in cell volume homeostasis 36318922 Process
65125 GO:0007165 IDA involved_in signal transduction 16669787 Process
65125 GO:0010507 IMP involved_in negative regulation of autophagy 27911840 Process
65125 GO:0010793 IDA involved_in regulation of mRNA export from nucleus 29196535 Process
65125 GO:0010820 IMP involved_in positive regulation of T cell chemotaxis 27400149 Process
65125 GO:0018107 IMP acts_upstream_of_or_within peptidyl-threonine phosphorylation 27782176 Process
65125 GO:0031397 IDA involved_in negative regulation of protein ubiquitination 33964204 Process
65125 GO:0033633 IMP involved_in negative regulation of cell-cell adhesion mediated by integrin 27400149 Process
65125 GO:0034115 IMP involved_in negative regulation of heterotypic cell-cell adhesion 27400149 Process
65125 GO:0034260 IMP acts_upstream_of_or_within negative regulation of GTPase activity 27400149 Process
65125 GO:0035556 IDA involved_in intracellular signal transduction 10660600 Process
65125 GO:0045050 IDA involved_in protein insertion into ER membrane by stop-transfer membrane-anchor sequence 33964204 Process
65125 GO:0045766 IMP involved_in positive regulation of angiogenesis 25362046 Process
65125 GO:0071474 IDA involved_in cellular hyperosmotic response 15883153,17190791,34289367,36318922 Process
65125 GO:0090263 IMP involved_in positive regulation of canonical Wnt signaling pathway 23797875 Process
65125 GO:0140694 IDA involved_in non-membrane-bounded organelle assembly 36318922 Process
65125 GO:1903038 IMP involved_in negative regulation of leukocyte cell-cell adhesion 27400149 Process
65125 GO:1903490 IDA involved_in positive regulation of mitotic cytokinesis 21220314 Process
65125 GO:1904062 IMP acts_upstream_of regulation of monoatomic cation transmembrane transport 27782176 Process
65125 GO:1904595 IDA involved_in positive regulation of termination of RNA polymerase II transcription 29196535 Process
65125 GO:1990869 IMP involved_in cellular response to chemokine 27400149 Process