Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 673
  • Symbol: BRAF
  • Description: B-Raf proto-oncogene, serine/threonine kinase

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
673 GO:0000165 IDA involved_in MAPK cascade 18567582,29433126 Process
673 GO:0006468 IDA involved_in protein phosphorylation 17563371 Process
673 GO:0007173 IDA involved_in epidermal growth factor receptor signaling pathway 18567582 Process
673 GO:0010628 IMP involved_in positive regulation of gene expression 22065586 Process
673 GO:0010828 IDA involved_in positive regulation of glucose transmembrane transport 23010278 Process
673 GO:0033138 IDA involved_in positive regulation of peptidyl-serine phosphorylation 19667065 Process
673 GO:0043066 IDA involved_in negative regulation of apoptotic process 19667065 Process
673 GO:0070374 IDA involved_in positive regulation of ERK1 and ERK2 cascade 22065586 Process
673 GO:0070413 IMP involved_in trehalose metabolism in response to stress 9837904 Process
673 GO:0071277 IDA involved_in cellular response to calcium ion 18567582 Process
673 GO:0090150 IDA involved_in establishment of protein localization to membrane 23010278 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
673 GO:0004672 IDA enables protein kinase activity 17563371 Function
673 GO:0004674 IDA enables protein serine/threonine kinase activity 18567582,19667065 Function
673 GO:0004708 IMP enables MAP kinase kinase activity 29433126 Function
673 GO:0005509 IDA enables calcium ion binding 18567582 Function
673 GO:0005515 IPI enables protein binding 12620389,15161933,15778465,16810323,16888650,17380122,17563371..... Function
673 GO:0031267 IPI NOT enables small GTPase binding 12194967 Function
673 GO:0042802 IPI enables identical protein binding 16858395,19727074,22169110,22510884,25155755,25437913..... Function
673 GO:0097110 IPI enables scaffold protein binding 18567582 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
673 GO:0005829 IDA located_in cytosol Component
673 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component