Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 695
• Symbol: BTK
• Description: Bruton tyrosine kinase

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
695	GO:0004713	EXP	enables	protein tyrosine kinase activity	7518558	Function
695	GO:0004713	IDA	enables	protein tyrosine kinase activity	34554188	Function
695	GO:0004715	IDA	enables	non-membrane spanning protein tyrosine kinase activity	11606584	Function
695	GO:0004715	IGI	enables	non-membrane spanning protein tyrosine kinase activity	14656219	Function
695	GO:0005515	IPI	enables	protein binding	8892607,9012831,9571151,11788586,15046600,15539407,16969585,19.....	Function
695	GO:0005547	IDA	enables	phosphatidylinositol-3,4,5-trisphosphate binding	17823121	Function
695	GO:0016004	IDA	enables	phospholipase activator activity	11606584	Function
695	GO:0042802	IPI	enables	identical protein binding	11577348	Function
695	GO:0043274	IPI	enables	phospholipase binding	11606584,14656219	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
695	GO:0005829	IDA	located_in	cytosol	17823121	Component
695	GO:0005886	IDA	located_in	plasma membrane	17823121	Component
695	GO:0045121	IDA	located_in	membrane raft	15046600	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
695	GO:0018108	IDA	involved_in	peptidyl-tyrosine phosphorylation	11606584,15509800	Process
695	GO:0018108	IGI	involved_in	peptidyl-tyrosine phosphorylation	14656219	Process
695	GO:0035556	IDA	involved_in	intracellular signal transduction	11606584,15509800	Process
695	GO:0035556	IGI	involved_in	intracellular signal transduction	14656219	Process
695	GO:0050853	IDA	involved_in	B cell receptor signaling pathway	15509800	Process
695	GO:1900227	IDA	involved_in	positive regulation of NLRP3 inflammasome complex assembly	34554188	Process