Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 7023
  • Symbol: TFAP4
  • Description: transcription factor AP-4

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7023 GO:0000976 IDA enables transcription cis-regulatory region binding 2833704,14645924,16540471 Function
7023 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 2833704 Function
7023 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 2833704 Function
7023 GO:0003677 IDA enables DNA binding 9931457 Function
7023 GO:0005515 IPI enables protein binding 16924111,19505873,25416956,32296183,32814053 Function
7023 GO:0042803 IPI enables protein homodimerization activity 2123466 Function
7023 GO:0042826 IPI enables histone deacetylase binding 16540471,16924111 Function
7023 GO:0043565 IDA enables sequence-specific DNA binding 2123466 Function
7023 GO:0070888 IDA enables E-box binding 7933101,11171123,12663744,18818310,19505873 Function
7023 GO:1990837 IDA enables sequence-specific double-stranded DNA binding 28473536 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7023 GO:0005634 IDA located_in nucleus 7933101,9931457,11171123,12663744,19505873 Component
7023 GO:0005654 IDA located_in nucleoplasm Component
7023 GO:0005739 IDA located_in mitochondrion Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7023 GO:0006978 IDA involved_in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 18818310 Process
7023 GO:0008285 IMP involved_in negative regulation of cell population proliferation 18818310 Process
7023 GO:0043065 IDA involved_in positive regulation of apoptotic process 18818310 Process
7023 GO:0043392 IDA involved_in negative regulation of DNA binding 7933101,16540471 Process
7023 GO:0043922 IDA involved_in negative regulation by host of viral transcription 14645924,16540471 Process
7023 GO:0043923 IDA involved_in positive regulation by host of viral transcription 2833704 Process
7023 GO:0045736 IDA involved_in negative regulation of cyclin-dependent protein serine/threonine kinase activity 18818310 Process
7023 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 9931457,16924111,19505873 Process
7023 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 18818310 Process
7023 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 12663744 Process
7023 GO:0065003 IDA involved_in protein-containing complex assembly 19505873 Process
7023 GO:1901990 IDA involved_in regulation of mitotic cell cycle phase transition 18818310 Process