Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 90
• Symbol: ACVR1
• Description: activin A receptor type 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
90	GO:0003143	IMP	involved_in	embryonic heart tube morphogenesis	19506109	Process
90	GO:0003183	IMP	involved_in	mitral valve morphogenesis	19506109	Process
90	GO:0003289	IMP	involved_in	atrial septum primum morphogenesis	19506109	Process
90	GO:0006468	IDA	involved_in	protein phosphorylation	12065756,19506109	Process
90	GO:0007179	IDA	involved_in	transforming growth factor beta receptor signaling pathway	8242742	Process
90	GO:0009968	IMP	involved_in	negative regulation of signal transduction	9884026	Process
90	GO:0010862	IDA	involved_in	positive regulation of pathway-restricted SMAD protein phosphorylation	19506109	Process
90	GO:0018107	IDA	involved_in	peptidyl-threonine phosphorylation	19736306	Process
90	GO:0030278	IMP	involved_in	regulation of ossification	16642017	Process
90	GO:0030335	IGI	involved_in	positive regulation of cell migration	19736306	Process
90	GO:0030501	IMP	involved_in	positive regulation of bone mineralization	18436533	Process
90	GO:0030509	IDA	involved_in	BMP signaling pathway	18436533	Process
90	GO:0032924	IDA	involved_in	activin receptor signaling pathway	19506109	Process
90	GO:0032924	IMP	involved_in	activin receptor signaling pathway	18326817	Process
90	GO:0032926	IMP	involved_in	negative regulation of activin receptor signaling pathway	9884026	Process
90	GO:0045669	IMP	involved_in	positive regulation of osteoblast differentiation	18436533	Process
90	GO:0045893	IDA	involved_in	positive regulation of DNA-templated transcription	8242742	Process
90	GO:0045944	IDA	involved_in	positive regulation of transcription by RNA polymerase II	19506109	Process
90	GO:0045944	IMP	involved_in	positive regulation of transcription by RNA polymerase II	18326817	Process
90	GO:0050731	IMP	involved_in	positive regulation of peptidyl-tyrosine phosphorylation	26598555	Process
90	GO:0060389	IDA	involved_in	pathway-restricted SMAD protein phosphorylation	19736306	Process
90	GO:0060923	IMP	involved_in	cardiac muscle cell fate commitment	19506109	Process
90	GO:0061445	IMP	involved_in	endocardial cushion cell fate commitment	19506109	Process
90	GO:0071773	IMP	involved_in	cellular response to BMP stimulus	18326817	Process
90	GO:2000017	IDA	involved_in	positive regulation of determination of dorsal identity	19506109	Process
90	GO:2000134	IMP	involved_in	negative regulation of G1/S transition of mitotic cell cycle	9884026	Process
90	GO:2001237	IMP	involved_in	negative regulation of extrinsic apoptotic signaling pathway	9884026	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
90	GO:0004672	IDA	enables	protein kinase activity	19736306	Function
90	GO:0004674	IDA	enables	protein serine/threonine kinase activity	12065756	Function
90	GO:0005515	IPI	enables	protein binding	8242742,8555189,11266516,18436533,31483918	Function
90	GO:0005524	IDA	enables	ATP binding	12065756	Function
90	GO:0016361	IDA	contributes_to	activin receptor activity, type I	8242742	Function
90	GO:0042803	IDA	enables	protein homodimerization activity	18436533	Function
90	GO:0045296	IPI	enables	cadherin binding	26598555	Function
90	GO:0046332	IDA	enables	SMAD binding	12065756	Function
90	GO:0048185	IDA	enables	activin binding	8242742	Function
90	GO:0050431	IDA	enables	transforming growth factor beta binding	8242742	Function
90	GO:1990782	IPI	enables	protein tyrosine kinase binding	26598555	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
90	GO:0005886	IDA	located_in	plasma membrane	8242742	Component
90	GO:0048179	IDA	part_of	activin receptor complex	8242742	Component