Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 94
• Symbol: ACVRL1
• Description: activin A receptor like type 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
94	GO:0001525	IMP	involved_in	angiogenesis	16752392	Process
94	GO:0006355	IMP	involved_in	regulation of DNA-templated transcription	15702480	Process
94	GO:0006468	IDA	involved_in	protein phosphorylation	12065756	Process
94	GO:0007162	IMP	involved_in	negative regulation of cell adhesion	12453878	Process
94	GO:0007165	IDA	involved_in	signal transduction	15702480	Process
94	GO:0007179	IDA	involved_in	transforming growth factor beta receptor signaling pathway	15702480	Process
94	GO:0008015	IMP	involved_in	blood circulation	16752392	Process
94	GO:0008217	IMP	involved_in	regulation of blood pressure	14684682	Process
94	GO:0008285	IMP	involved_in	negative regulation of cell population proliferation	12453878	Process
94	GO:0010596	IDA	involved_in	negative regulation of endothelial cell migration	17068149	Process
94	GO:0010862	IMP	involved_in	positive regulation of pathway-restricted SMAD protein phosphorylation	19366699	Process
94	GO:0030308	IDA	involved_in	negative regulation of cell growth	17068149	Process
94	GO:0030336	IMP	involved_in	negative regulation of cell migration	12453878	Process
94	GO:0030509	IMP	involved_in	BMP signaling pathway	19366699	Process
94	GO:0030513	IDA	involved_in	positive regulation of BMP signaling pathway	17068149	Process
94	GO:0035313	IMP	involved_in	wound healing, spreading of epidermal cells	12453878	Process
94	GO:0043537	IMP	involved_in	negative regulation of blood vessel endothelial cell migration	19592636	Process
94	GO:0045893	IDA	involved_in	positive regulation of DNA-templated transcription	12393874	Process
94	GO:0045944	IDA	involved_in	positive regulation of transcription by RNA polymerase II	19366699	Process
94	GO:0051895	IMP	involved_in	negative regulation of focal adhesion assembly	12453878	Process
94	GO:0060836	IMP	involved_in	lymphatic endothelial cell differentiation	19903896	Process
94	GO:0061154	IMP	involved_in	endothelial tube morphogenesis	19592636	Process
94	GO:0071560	IDA	involved_in	cellular response to transforming growth factor beta stimulus	19494318	Process
94	GO:0071773	IMP	involved_in	cellular response to BMP stimulus	19366699,19903896	Process
94	GO:2000279	IMP	involved_in	negative regulation of DNA biosynthetic process	19366699	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
94	GO:0004674	IDA	enables	protein serine/threonine kinase activity	12065756,12393874	Function
94	GO:0005024	IDA	enables	transforming growth factor beta receptor activity	8242742	Function
94	GO:0005025	IDA	enables	transforming growth factor beta receptor activity, type I	8242742	Function
94	GO:0005515	IPI	enables	protein binding	8242742,11266516,11278302,12393874,14580334,15611116,15702480,.....	Function
94	GO:0005524	IDA	enables	ATP binding	12065756	Function
94	GO:0016361	IDA	enables	activin receptor activity, type I	8242742	Function
94	GO:0019901	IPI	enables	protein kinase binding	19592636	Function
94	GO:0046332	IDA	enables	SMAD binding	12065756	Function
94	GO:0048185	IDA	enables	activin binding	8242742	Function
94	GO:0050431	IPI	enables	transforming growth factor beta binding	8242742	Function
94	GO:0098821	IMP	enables	BMP receptor activity	26176610	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
94	GO:0005886	IDA	located_in	plasma membrane	8242742,26176610	Component
94	GO:0009986	IDA	located_in	cell surface	8242742	Component