Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3706
• Symbol: ITPKA
• Description: inositol-trisphosphate 3-kinase A

DataSource: http://genomecrispr.dkfz.de/#!/results/ITPKA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41502811	41502834	15	+	26472758	Jiyoye	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.6760801221434787	[213]	[100]	-5	hSpCas9	negative selection	79963
41502057	41502080	15	+	26472758	Jiyoye	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	2.026085214150367	[13]	[42]	8	hSpCas9	negative selection	79964
41494154	41494177	15	-	26472758	Jiyoye	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-2.1535395729686053	[117]	[19]	-8	hSpCas9	negative selection	79965
41494233	41494256	15	+	26472758	Jiyoye	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	0.4727637231334503	[42]	[44]	3	hSpCas9	negative selection	79966
41494289	41494312	15	-	26472758	Jiyoye	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	4.407175381505873	[0]	[15]	9	hSpCas9	negative selection	79967
41494307	41494330	15	-	26472758	Jiyoye	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.32273545512638224	[135]	[81]	-2	hSpCas9	negative selection	79968
41494320	41494343	15	+	26472758	Jiyoye	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	5.107615099646965	[0]	[25]	9	hSpCas9	negative selection	79969
41494357	41494380	15	+	26472758	Jiyoye	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	2.214530303563478	[19]	[69]	9	hSpCas9	negative selection	79970
41501991	41502014	15	+	26472758	Jiyoye	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.6457863134004496	[138]	[163]	5	hSpCas9	negative selection	79971
41502030	41502053	15	+	26472758	Jiyoye	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	-0.7883754276119334	[212]	[92]	-5	hSpCas9	negative selection	79972
41502811	41502834	15	+	26472758	KBM7	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	0.3537672143770576	[732,294]	[402,201]	4	hSpCas9	negative selection	271081
41502057	41502080	15	+	26472758	KBM7	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.8803926877906469	[314,78]	[28,63]	-6	hSpCas9	negative selection	271082
41494154	41494177	15	-	26472758	KBM7	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-2.006737760730283	[191,92]	[31,1]	-8	hSpCas9	negative selection	271083
41494233	41494256	15	+	26472758	KBM7	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	-0.2344566701981461	[79,73]	[43,18]	-2	hSpCas9	negative selection	271084
41494289	41494312	15	-	26472758	KBM7	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	0.13672573783570785	[53,67]	[30,32]	1	hSpCas9	negative selection	271085
41494307	41494330	15	-	26472758	KBM7	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	0.505302209141568	[733,372]	[313,398]	5	hSpCas9	negative selection	271086
41494320	41494343	15	+	26472758	KBM7	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-0.7405223925791087	[41,63]	[18,11]	-6	hSpCas9	negative selection	271087
41494357	41494380	15	+	26472758	KBM7	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.697309933272044	[306,173]	[158,196]	7	hSpCas9	negative selection	271088
41501991	41502014	15	+	26472758	KBM7	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.6902444204478703	[457,547]	[500,284]	7	hSpCas9	negative selection	271089
41502030	41502053	15	+	26472758	KBM7	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.7300764110656495	[342,425]	[367,247]	7	hSpCas9	negative selection	271090
41502811	41502834	15	+	26472758	Raji	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-1.7429235318685516	[374]	[25]	-8	hSpCas9	negative selection	462199
41502057	41502080	15	+	26472758	Raji	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.8926164646264005	[127]	[15]	-6	hSpCas9	negative selection	462200
41494154	41494177	15	-	26472758	Raji	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-2.115008885962849	[55]	[2]	-8	hSpCas9	negative selection	462201
41494233	41494256	15	+	26472758	Raji	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	0.4944066584828468	[51]	[16]	5	hSpCas9	negative selection	462202
41494289	41494312	15	-	26472758	Raji	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	0.40694381723250705	[12]	[3]	4	hSpCas9	negative selection	462203
41494307	41494330	15	-	26472758	Raji	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.055555035752606174	[205]	[45]	0	hSpCas9	negative selection	462204
41494320	41494343	15	+	26472758	Raji	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	0.21985826463201175	[36]	[9]	2	hSpCas9	negative selection	462205
41494357	41494380	15	+	26472758	Raji	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	-0.1229140840481946	[182]	[38]	-1	hSpCas9	negative selection	462206
41501991	41502014	15	+	26472758	Raji	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	1.1873518400770144	[192]	[101]	9	hSpCas9	negative selection	462207
41502030	41502053	15	+	26472758	Raji	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.2509108467513045	[238]	[65]	2	hSpCas9	negative selection	462208
41502811	41502834	15	+	26472758	K562	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.9018996608235316	[393]	[177]	-5	hSpCas9	negative selection	653317
41502057	41502080	15	+	26472758	K562	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	1.6539810968791397	[98]	[262]	9	hSpCas9	negative selection	653318
41494154	41494177	15	-	26472758	K562	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-6.21501289097085	[87]	[0]	-9	hSpCas9	negative selection	653319
41494233	41494256	15	+	26472758	K562	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	0.4804860858999711	[44]	[52]	4	hSpCas9	negative selection	653320
41494289	41494312	15	-	26472758	K562	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	-0.719055396308439	[38]	[19]	-4	hSpCas9	negative selection	653321
41494307	41494330	15	-	26472758	K562	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	0.08067230115325891	[465]	[415]	0	hSpCas9	negative selection	653322
41494320	41494343	15	+	26472758	K562	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	0.6457812900482143	[52]	[69]	5	hSpCas9	negative selection	653323
41494357	41494380	15	+	26472758	K562	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	-0.6323098974318193	[212]	[115]	-4	hSpCas9	negative selection	653324
41501991	41502014	15	+	26472758	K562	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.11832484263265713	[465]	[426]	0	hSpCas9	negative selection	653325
41502030	41502053	15	+	26472758	K562	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.7063228319832648	[317]	[437]	6	hSpCas9	negative selection	653326
41494155	41494178	15	-	26627737	DLD1	viability	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	1.6827555323416248	[186]	[171,164,219]	9	hSpCas9	negative selection	790539
41501488	41501511	15	-	26627737	DLD1	viability	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-0.02074407679468595	[461]	[127,187,116]	0	hSpCas9	negative selection	790540
41501641	41501664	15	+	26627737	DLD1	viability	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.25911838867998216	[241]	[152,90,35]	2	hSpCas9	negative selection	790541
41502081	41502104	15	+	26627737	DLD1	viability	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.46445789576842184	[355]	[99,94,51]	-5	hSpCas9	negative selection	790542
41502434	41502457	15	+	26627737	DLD1	viability	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.7071022441345052	[141]	[105,49,61]	7	hSpCas9	negative selection	790543
41502802	41502825	15	-	26627737	DLD1	viability	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	0.6120885635359379	[60]	[77,11,0]	6	hSpCas9	negative selection	790544
41494155	41494178	15	-	26627737	GBM cells	viability after 5 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.07725111614419816	[189]	[102,111]	1	hSpCas9	negative selection	872854
41501488	41501511	15	-	26627737	GBM cells	viability after 5 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	0.5223505234214776	[147]	[120,106]	7	hSpCas9	negative selection	872855
41501641	41501664	15	+	26627737	GBM cells	viability after 5 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.071860228303235	[105]	[131,106]	9	hSpCas9	negative selection	872856
41502081	41502104	15	+	26627737	GBM cells	viability after 5 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.42866078314281886	[255]	[113,89]	-6	hSpCas9	negative selection	872857
41502434	41502457	15	+	26627737	GBM cells	viability after 5 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.08333844602311313	[153]	[108,65]	1	hSpCas9	negative selection	872858
41502802	41502825	15	-	26627737	GBM cells	viability after 5 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-0.9941709211978023	[64]	[6,27]	-9	hSpCas9	negative selection	872859
41494155	41494178	15	-	26627737	GBM cells	viability after 13 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.4761931135331461	[189]	[122,159]	6	hSpCas9	negative selection	955169
41501488	41501511	15	-	26627737	GBM cells	viability after 13 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	0.4086536769772743	[147]	[126,89]	5	hSpCas9	negative selection	955170
41501641	41501664	15	+	26627737	GBM cells	viability after 13 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.3697156687609042	[105]	[157,140]	9	hSpCas9	negative selection	955171
41502081	41502104	15	+	26627737	GBM cells	viability after 13 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.3732608716327576	[255]	[168,56]	-4	hSpCas9	negative selection	955172
41502434	41502457	15	+	26627737	GBM cells	viability after 13 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.6936583971444221	[153]	[65,39]	-7	hSpCas9	negative selection	955173
41502802	41502825	15	-	26627737	GBM cells	viability after 13 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-1.64088774273852	[64]	[7,13]	-9	hSpCas9	negative selection	955174
41494155	41494178	15	-	26627737	GBM cells	viability after 21 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.9092986495957863	[189]	[196,190]	8	hSpCas9	negative selection	1037484
41501488	41501511	15	-	26627737	GBM cells	viability after 21 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-0.006690973391393573	[147]	[90,69]	0	hSpCas9	negative selection	1037485
41501641	41501664	15	+	26627737	GBM cells	viability after 21 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.14528264298493	[105]	[141,113]	9	hSpCas9	negative selection	1037486
41502081	41502104	15	+	26627737	GBM cells	viability after 21 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.9815802440579195	[255]	[71,68]	-7	hSpCas9	negative selection	1037487
41502434	41502457	15	+	26627737	GBM cells	viability after 21 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.5039101917174016	[153]	[58,58]	-4	hSpCas9	negative selection	1037488
41502802	41502825	15	-	26627737	GBM cells	viability after 21 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-0.9378894387866075	[64]	[19,16]	-7	hSpCas9	negative selection	1037489
41494155	41494178	15	-	26627737	RPE1	viability after 9 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-0.1767174639912168	[501]	[128,151]	-1	hSpCas9	negative selection	1119799
41501488	41501511	15	-	26627737	RPE1	viability after 9 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-1.1709503218568165	[890]	[129,115]	-7	hSpCas9	negative selection	1119800
41501641	41501664	15	+	26627737	RPE1	viability after 9 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.407553455481332	[216]	[167,195]	7	hSpCas9	negative selection	1119801
41502081	41502104	15	+	26627737	RPE1	viability after 9 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.27323707593864577	[824]	[228,193]	-2	hSpCas9	negative selection	1119802
41502434	41502457	15	+	26627737	RPE1	viability after 9 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.8679713686404533	[337]	[100,311]	5	hSpCas9	negative selection	1119803
41502802	41502825	15	-	26627737	RPE1	viability after 9 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	8.092585898848634	[1]	[128,224]	9	hSpCas9	negative selection	1119804
41494155	41494178	15	-	26627737	RPE1	viability after 12 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-0.4733961281975366	[501]	[33,163]	-3	hSpCas9	negative selection	1202114
41501488	41501511	15	-	26627737	RPE1	viability after 12 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-1.6449743609513716	[890]	[77,74]	-8	hSpCas9	negative selection	1202115
41501641	41501664	15	+	26627737	RPE1	viability after 12 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.9297185546228892	[216]	[78,144]	6	hSpCas9	negative selection	1202116
41502081	41502104	15	+	26627737	RPE1	viability after 12 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.4464485300138604	[824]	[218,102]	-3	hSpCas9	negative selection	1202117
41502434	41502457	15	+	26627737	RPE1	viability after 12 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.4534117996963263	[337]	[101,147]	3	hSpCas9	negative selection	1202118
41502802	41502825	15	-	26627737	RPE1	viability after 12 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	7.602484085567971	[1]	[135,70]	9	hSpCas9	negative selection	1202119
41494155	41494178	15	-	26627737	RPE1	viability after 15 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-0.24442809657710296	[501]	[126,112]	-1	hSpCas9	negative selection	1284429
41501488	41501511	15	-	26627737	RPE1	viability after 15 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-0.23576074527681712	[890]	[323,107]	-1	hSpCas9	negative selection	1284430
41501641	41501664	15	+	26627737	RPE1	viability after 15 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.2384399953815854	[216]	[97,189]	7	hSpCas9	negative selection	1284431
41502081	41502104	15	+	26627737	RPE1	viability after 15 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.45354369447284676	[824]	[202,138]	-3	hSpCas9	negative selection	1284432
41502434	41502457	15	+	26627737	RPE1	viability after 15 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.1691637384168052	[337]	[54,113]	-1	hSpCas9	negative selection	1284433
41502802	41502825	15	-	26627737	RPE1	viability after 15 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	8.416149481340291	[1]	[262,125]	9	hSpCas9	negative selection	1284434
41494155	41494178	15	-	26627737	RPE1	viability after 18 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.37720664175718355	[501]	[28,332]	2	hSpCas9	negative selection	1366744
41501488	41501511	15	-	26627737	RPE1	viability after 18 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-1.02367126673951	[890]	[198,31]	-6	hSpCas9	negative selection	1366745
41501641	41501664	15	+	26627737	RPE1	viability after 18 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.4443931967123163	[216]	[111,209]	7	hSpCas9	negative selection	1366746
41502081	41502104	15	+	26627737	RPE1	viability after 18 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.38943245368893237	[824]	[241,92]	-2	hSpCas9	negative selection	1366747
41502434	41502457	15	+	26627737	RPE1	viability after 18 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.20505159655579774	[337]	[123,84]	1	hSpCas9	negative selection	1366748
41502802	41502825	15	-	26627737	RPE1	viability after 18 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	8.721118099410786	[1]	[395,47]	9	hSpCas9	negative selection	1366749
41494155	41494178	15	-	26627737	HeLa	viability after 8 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-0.025992214179629047	[209]	[23,99,127]	0	hSpCas9	negative selection	1449059
41501488	41501511	15	-	26627737	HeLa	viability after 8 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	0.16091578049292715	[266]	[74,163,137]	1	hSpCas9	negative selection	1449060
41501641	41501664	15	+	26627737	HeLa	viability after 8 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.668783372464909	[192]	[190,174,52]	6	hSpCas9	negative selection	1449061
41502081	41502104	15	+	26627737	HeLa	viability after 8 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	0.09699166367097362	[320]	[136,107,196]	0	hSpCas9	negative selection	1449062
41502434	41502457	15	+	26627737	HeLa	viability after 8 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.6518188734266928	[123]	[190,35,52]	5	hSpCas9	negative selection	1449063
41502802	41502825	15	-	26627737	HeLa	viability after 8 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-1.2031463650540373	[146]	[0,41,33]	-8	hSpCas9	negative selection	1449064
41494155	41494178	15	-	26627737	HeLa	viability after 12 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.42295451004775475	[209]	[130,101,117]	3	hSpCas9	negative selection	1531374
41501488	41501511	15	-	26627737	HeLa	viability after 12 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-1.1191716241914813	[266]	[69,21,63]	-8	hSpCas9	negative selection	1531375
41501641	41501664	15	+	26627737	HeLa	viability after 12 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.41525120684854233	[192]	[255,34,39]	3	hSpCas9	negative selection	1531376
41502081	41502104	15	+	26627737	HeLa	viability after 12 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.4389697675099819	[320]	[165,36,98]	-4	hSpCas9	negative selection	1531377
41502434	41502457	15	+	26627737	HeLa	viability after 12 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.6207070133024257	[123]	[37,24,37]	-5	hSpCas9	negative selection	1531378
41502802	41502825	15	-	26627737	HeLa	viability after 12 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	0.22622885320266128	[146]	[189,29,0]	2	hSpCas9	negative selection	1531379
41494155	41494178	15	-	26627737	HeLa	viability after 15 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	1.2691302170127798	[209]	[269,277,57]	8	hSpCas9	negative selection	1613689
41501488	41501511	15	-	26627737	HeLa	viability after 15 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-0.08815814776112141	[266]	[88,138,76]	0	hSpCas9	negative selection	1613690
41501641	41501664	15	+	26627737	HeLa	viability after 15 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.2757852280712272	[192]	[68,117,98]	2	hSpCas9	negative selection	1613691
41502081	41502104	15	+	26627737	HeLa	viability after 15 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	0.2186357637678576	[320]	[212,58,185]	1	hSpCas9	negative selection	1613692
41502434	41502457	15	+	26627737	HeLa	viability after 15 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.9656293853618387	[123]	[143,114,30]	7	hSpCas9	negative selection	1613693
41502802	41502825	15	-	26627737	HeLa	viability after 15 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-1.0231389937749162	[146]	[52,5,28]	-7	hSpCas9	negative selection	1613694
41494155	41494178	15	-	26627737	HeLa	viability after 18 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	1.2880326063490266	[209]	[180,236,57]	8	hSpCas9	negative selection	1696004
41501488	41501511	15	-	26627737	HeLa	viability after 18 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-0.08520585052868213	[266]	[60,113,76]	0	hSpCas9	negative selection	1696005
41501641	41501664	15	+	26627737	HeLa	viability after 18 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.3076916906238738	[192]	[50,96,98]	2	hSpCas9	negative selection	1696006
41502081	41502104	15	+	26627737	HeLa	viability after 18 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	0.18208861474265334	[320]	[132,51,185]	1	hSpCas9	negative selection	1696007
41502434	41502457	15	+	26627737	HeLa	viability after 18 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	1.0404126784176677	[123]	[102,99,30]	7	hSpCas9	negative selection	1696008
41502802	41502825	15	-	26627737	HeLa	viability after 18 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-0.9431779386461383	[146]	[37,5,28]	-7	hSpCas9	negative selection	1696009
41494155	41494178	15	-	26627737	HCT116	viability after 6 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.1576815440077453	[580]	[117,92]	0	hSpCas9	negative selection	1778319
41501488	41501511	15	-	26627737	HCT116	viability after 6 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-1.092427105195045	[382]	[73,2]	-6	hSpCas9	negative selection	1778320
41501641	41501664	15	+	26627737	HCT116	viability after 6 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.8833742754996842	[305]	[51,108]	5	hSpCas9	negative selection	1778321
41502081	41502104	15	+	26627737	HCT116	viability after 6 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.3180364236998977	[604]	[45,92]	-2	hSpCas9	negative selection	1778322
41502434	41502457	15	+	26627737	HCT116	viability after 6 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.8220025422762732	[358]	[87,0]	-5	hSpCas9	negative selection	1778323
41502802	41502825	15	-	26627737	HCT116	viability after 6 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	8.76584427716641	[0]	[12,98]	9	hSpCas9	negative selection	1778324
41494155	41494178	15	-	26627737	HCT116	viability after 8 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-0.1318753315854975	[261]	[149,146,98]	-1	hSpCas9	negative selection	1860634
41501488	41501511	15	-	26627737	HCT116	viability after 8 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	0.4441590869921609	[129]	[39,124,125]	4	hSpCas9	negative selection	1860635
41501641	41501664	15	+	26627737	HCT116	viability after 8 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.3887947329433428	[68]	[86,73,136]	9	hSpCas9	negative selection	1860636
41502081	41502104	15	+	26627737	HCT116	viability after 8 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.31358171285149766	[250]	[83,106,141]	-4	hSpCas9	negative selection	1860637
41502434	41502457	15	+	26627737	HCT116	viability after 8 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.4049863483005112	[172]	[56,158,160]	4	hSpCas9	negative selection	1860638
41502802	41502825	15	-	26627737	HCT116	viability after 8 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	3.736885539834069	[6]	[17,27,106]	9	hSpCas9	negative selection	1860639
41494155	41494178	15	-	26627737	HCT116	viability after 9 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-0.21763380508855293	[580]	[138,128]	-1	hSpCas9	negative selection	1942949
41501488	41501511	15	-	26627737	HCT116	viability after 9 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-1.9539416876119842	[382]	[55,2]	-8	hSpCas9	negative selection	1942950
41501641	41501664	15	+	26627737	HCT116	viability after 9 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	-0.9684602741763959	[305]	[24,54]	-6	hSpCas9	negative selection	1942951
41502081	41502104	15	+	26627737	HCT116	viability after 9 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-2.149363780778859	[604]	[41,31]	-8	hSpCas9	negative selection	1942952
41502434	41502457	15	+	26627737	HCT116	viability after 9 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-1.3783231373766038	[358]	[80,1]	-7	hSpCas9	negative selection	1942953
41502802	41502825	15	-	26627737	HCT116	viability after 9 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	5.247565057083592	[0]	[3,14]	9	hSpCas9	negative selection	1942954
41494155	41494178	15	-	26627737	HCT116	viability after 12 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.2162057308306871	[261]	[238,163,69]	2	hSpCas9	negative selection	2025264
41501488	41501511	15	-	26627737	HCT116	viability after 12 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	1.073748608181544	[129]	[219,72,129]	8	hSpCas9	negative selection	2025265
41501641	41501664	15	+	26627737	HCT116	viability after 12 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	2.1974417769710466	[68]	[197,117,178]	9	hSpCas9	negative selection	2025266
41502081	41502104	15	+	26627737	HCT116	viability after 12 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.045107975319280846	[250]	[130,116,134]	0	hSpCas9	negative selection	2025267
41502434	41502457	15	+	26627737	HCT116	viability after 12 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.16846865476365813	[172]	[78,119,109]	1	hSpCas9	negative selection	2025268
41502802	41502825	15	-	26627737	HCT116	viability after 12 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	3.357623423210807	[6]	[24,68,20]	9	hSpCas9	negative selection	2025269
41494155	41494178	15	-	26627737	HCT116	viability after 15 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-0.31664547220042283	[261]	[113,75,170]	-3	hSpCas9	negative selection	2107579
41501488	41501511	15	-	26627737	HCT116	viability after 15 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	0.5570626066407556	[129]	[47,80,191]	5	hSpCas9	negative selection	2107580
41501641	41501664	15	+	26627737	HCT116	viability after 15 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	2.008164275915644	[68]	[109,185,175]	9	hSpCas9	negative selection	2107581
41502081	41502104	15	+	26627737	HCT116	viability after 15 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.05110903910220055	[250]	[185,89,146]	0	hSpCas9	negative selection	2107582
41502434	41502457	15	+	26627737	HCT116	viability after 15 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.4616659290152427	[172]	[40,128,42]	-5	hSpCas9	negative selection	2107583
41502802	41502825	15	-	26627737	HCT116	viability after 15 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	3.6305546138941875	[6]	[8,134,0]	9	hSpCas9	negative selection	2107584
41494155	41494178	15	-	26627737	HCT116	viability after 18 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.15831704756066883	[261]	[239,109,72]	1	hSpCas9	negative selection	2189894
41501488	41501511	15	-	26627737	HCT116	viability after 18 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	1.566235379027952	[129]	[227,51,291]	9	hSpCas9	negative selection	2189895
41501641	41501664	15	+	26627737	HCT116	viability after 18 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.687449165274359	[68]	[104,76,143]	9	hSpCas9	negative selection	2189896
41502081	41502104	15	+	26627737	HCT116	viability after 18 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.1378828634654634	[250]	[81,94,156]	-1	hSpCas9	negative selection	2189897
41502434	41502457	15	+	26627737	HCT116	viability after 18 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.3591017943095973	[172]	[22,104,64]	-3	hSpCas9	negative selection	2189898
41502802	41502825	15	-	26627737	HCT116	viability after 18 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	3.760442976763997	[6]	[0,94,37]	9	hSpCas9	negative selection	2189899
41493677	41493700	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGGAAGTCCAGCCTCCGTAGG	ITPKA	ENSG00000137825	2.126253314904198	[8,17]	[11,14]	7	dCas9-VP64	positive selection	2429934
41493705	41493728	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGGCTCTCGGTGACTCCTCGG	ITPKA	ENSG00000137825	-1.4906022792370845	[177,318]	[19,17]	-8	dCas9-VP64	positive selection	2429935
41493762	41493785	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCTGAAAGTGGAAGGAGTGGG	ITPKA	ENSG00000137825	-1.6985138897020624	[63,381]	[3,26]	-8	dCas9-VP64	positive selection	2429936
41493677	41493700	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGGAAGTCCAGCCTCCGTAGG	ITPKA	ENSG00000137825	-0.5843764645281472	[167,80]	[34,18]	-6	dCas9-VP64	positive selection	2525189
41493705	41493728	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGGCTCTCGGTGACTCCTCGG	ITPKA	ENSG00000137825	0.12555760311035202	[388,422]	[182,107]	1	dCas9-VP64	positive selection	2525190
41493762	41493785	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCTGAAAGTGGAAGGAGTGGG	ITPKA	ENSG00000137825	-0.045676053358174984	[168,131]	[60,34]	0	dCas9-VP64	positive selection	2525191
41494316	41494339	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAGTCCTCGAGCAGCGACGAGG	ITPKA	ENSG00000137825	0.07112569675373273	[4,3]	[3,3]	1	hSpCas9	positive selection	2996254
41501713	41501736	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.0768114093070468	[3,3]	[4,1]	-1	hSpCas9	positive selection	2996255
41494276	41494299	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACGAGGTGGAAAGGCGGCGCGG	ITPKA	ENSG00000137825	-0.43582214795033447	[3,3]	[2,1]	-6	hSpCas9	positive selection	2996256
41494154	41494177	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.796220831263319	[1,2]	[0,0]	-8	hSpCas9	positive selection	2996257
41494316	41494339	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAGTCCTCGAGCAGCGACGAGG	ITPKA	ENSG00000137825	0.21894116150422974	[4,4]	[4,2]	4	hSpCas9	positive selection	3064112
41501713	41501736	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.11214084892956266	[3,3]	[3,2]	2	hSpCas9	positive selection	3064113
41494276	41494299	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACGAGGTGGAAAGGCGGCGCGG	ITPKA	ENSG00000137825	-0.9727410640807257	[3,3]	[1,0]	-9	hSpCas9	positive selection	3064114
41494154	41494177	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.008144490082918843	[1,1]	[2,0]	0	hSpCas9	positive selection	3064115
41501988	41502011		+	24336571	A375	resistance to PLX after 7 days	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	-0.08843625577427638	[9,7]	[8,6]	-3	hSpCas9	positive selection	3121884
41501750	41501773		-	24336571	A375	resistance to PLX after 7 days	CGTCGCGCTCCACCACGCCGTGG	ITPKA	ENSG00000137825	-0.13633550416322093	[10,8]	[8,8]	-4	hSpCas9	positive selection	3121886
41501712	41501735		+	24336571	A375	resistance to PLX after 7 days	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.3483986375938704	[15,16]	[20,20]	8	hSpCas9	positive selection	3121887
41502092	41502115		-	24336571	A375	resistance to PLX after 7 days	CTGCGCGTGCTCCTCCTCCGTGG	ITPKA	ENSG00000137825	-0.27374141505147764	[4,5]	[4,3]	-7	hSpCas9	positive selection	3121888
41501988	41502011		+	24336571	A375	resistance to PLX after 14 days	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.1484923789250677	[13,9]	[4,6]	1	hSpCas9	positive selection	3179677
41501750	41501773		-	24336571	A375	resistance to PLX after 14 days	CGTCGCGCTCCACCACGCCGTGG	ITPKA	ENSG00000137825	0.24870257798972117	[5,4]	[2,1]	2	hSpCas9	positive selection	3179679
41501712	41501735		+	24336571	A375	resistance to PLX after 14 days	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.617552320802222	[13,20]	[14,9]	5	hSpCas9	positive selection	3179680
41502092	41502115		-	24336571	A375	resistance to PLX after 14 days	CTGCGCGTGCTCCTCCTCCGTGG	ITPKA	ENSG00000137825	0.8036312572450173	[3,2]	[2,2]	6	hSpCas9	positive selection	3179681
41501988	41502011		+	24336571	A375	viability after 7 days	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.13892840137452955	[7]	[9,7]	2	hSpCas9	negative selection	3237470
41501750	41501773		-	24336571	A375	viability after 7 days	CGTCGCGCTCCACCACGCCGTGG	ITPKA	ENSG00000137825	-0.384258111353962	[13]	[10,8]	-5	hSpCas9	negative selection	3237472
41501712	41501735		+	24336571	A375	viability after 7 days	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.39377332463265546	[12]	[15,16]	6	hSpCas9	negative selection	3237473
41502092	41502115		-	24336571	A375	viability after 7 days	CTGCGCGTGCTCCTCCTCCGTGG	ITPKA	ENSG00000137825	0.10934090136902097	[4]	[4,5]	1	hSpCas9	negative selection	3237474
41501988	41502011		+	24336571	A375	viability after 14 days	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.59241009965453	[7]	[13,9]	7	hSpCas9	negative selection	3295263
41501750	41501773		-	24336571	A375	viability after 14 days	CGTCGCGCTCCACCACGCCGTGG	ITPKA	ENSG00000137825	-1.1563299176600779	[13]	[5,4]	-9	hSpCas9	negative selection	3295265
41501712	41501735		+	24336571	A375	viability after 14 days	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.5291390755907442	[12]	[13,20]	6	hSpCas9	negative selection	3295266
41502092	41502115		-	24336571	A375	viability after 14 days	CTGCGCGTGCTCCTCCTCCGTGG	ITPKA	ENSG00000137825	-0.4238127999996957	[4]	[3,2]	-5	hSpCas9	negative selection	3295267
41501483	41501506	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.759482076240719	[258,258]	[0,0]	-5	hSpCas9	positive selection	3374853
41502828	41502851	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	1.257326211445835	[63,63]	[0,0]	5	hSpCas9	positive selection	3374854
41502038	41502061	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.5240335020788246	[219,219]	[0,0]	-3	hSpCas9	positive selection	3374855
41494316	41494339	15	-	26780180	HT29	viability (Avana library 4 designs)	CGAGTCCTCGAGCAGCGACGAGG	ITPKA	ENSG00000137825	1.3373407102663	[]	[]	5	hSpCas9	negative selection	3433650
41501712	41501735	15	+	26780180	HT29	viability (Avana library 4 designs)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.327477202972864	[]	[]	1	hSpCas9	negative selection	3433651
41494276	41494299	15	-	26780180	HT29	viability (Avana library 4 designs)	GACGAGGTGGAAAGGCGGCGCGG	ITPKA	ENSG00000137825	4.3669510557523	[]	[]	9	hSpCas9	negative selection	3433652
41494154	41494177	15	-	26780180	HT29	viability (Avana library 4 designs)	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	2.70002748003267	[]	[]	8	hSpCas9	negative selection	3433653
41494154	41494177	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.826279717567784	[]	[]	-1	hSpCas9	negative selection	3520364
41501712	41501735	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	7.48967460181892	[]	[]	9	hSpCas9	negative selection	3520365
41494316	41494339	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAGTCCTCGAGCAGCGACGAGG	ITPKA	ENSG00000137825	4.54091440597062	[]	[]	7	hSpCas9	negative selection	3520366
41494276	41494299	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACGAGGTGGAAAGGCGGCGCGG	ITPKA	ENSG00000137825	1.14296055470394	[]	[]	1	hSpCas9	negative selection	3520367
41494242	41494265	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGAAGAGCCCGCTGCCGGGAGG	ITPKA	ENSG00000137825	4.10448167105572	[]	[]	6	hSpCas9	negative selection	3520368
41501663	41501686	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGATCCTGAAGCGCTGCTCGG	ITPKA	ENSG00000137825	4.22513073396122	[]	[]	7	hSpCas9	negative selection	3520369
41494154	41494177	15	-	26780180	A375	viability (Avana lentiGuide)	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	15.7815376468337	[]	[]	8	hSpCas9	negative selection	3629023
41501712	41501735	15	+	26780180	A375	viability (Avana lentiGuide)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.298813725727116	[]	[]	0	hSpCas9	negative selection	3629024
41494316	41494339	15	-	26780180	A375	viability (Avana lentiGuide)	CGAGTCCTCGAGCAGCGACGAGG	ITPKA	ENSG00000137825	2.44922492023284	[]	[]	2	hSpCas9	negative selection	3629025
41494276	41494299	15	-	26780180	A375	viability (Avana lentiGuide)	GACGAGGTGGAAAGGCGGCGCGG	ITPKA	ENSG00000137825	19.6241515843921	[]	[]	8	hSpCas9	negative selection	3629026
41494242	41494265	15	-	26780180	A375	viability (Avana lentiGuide)	GCGAAGAGCCCGCTGCCGGGAGG	ITPKA	ENSG00000137825	3.89154495777853	[]	[]	4	hSpCas9	negative selection	3629027
41501663	41501686	15	+	26780180	A375	viability (Avana lentiGuide)	GCTGATCCTGAAGCGCTGCTCGG	ITPKA	ENSG00000137825	-3.72444304982779	[]	[]	-6	hSpCas9	negative selection	3629028
41494154	41494177	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.2846895955656844	[4]	[3,3]	-4	hSpCas9	positive selection	3737682
41501712	41501735	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.30912196724041896	[5]	[7,5]	8	hSpCas9	positive selection	3737683
41494316	41494339	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAGTCCTCGAGCAGCGACGAGG	ITPKA	ENSG00000137825	0.05953853772218777	[5]	[5,4]	1	hSpCas9	positive selection	3737684
41494276	41494299	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACGAGGTGGAAAGGCGGCGCGG	ITPKA	ENSG00000137825	-0.020921819468222164	[5]	[5,4]	0	hSpCas9	positive selection	3737685
41494242	41494265	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGAAGAGCCCGCTGCCGGGAGG	ITPKA	ENSG00000137825	0.25118844691156567	[4]	[5,4]	7	hSpCas9	positive selection	3737686
41501663	41501686	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGATCCTGAAGCGCTGCTCGG	ITPKA	ENSG00000137825	0.1797382418053523	[6]	[7,6]	5	hSpCas9	positive selection	3737687
41494154	41494177	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.5734209237106132	[4]	[2,1]	-6	hSpCas9	positive selection	3846289
41501712	41501735	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.23197461230793015	[5]	[4,3]	-3	hSpCas9	positive selection	3846290
41494316	41494339	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAGTCCTCGAGCAGCGACGAGG	ITPKA	ENSG00000137825	-0.2996945775066553	[6]	[2,5]	-4	hSpCas9	positive selection	3846291
41494276	41494299	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACGAGGTGGAAAGGCGGCGCGG	ITPKA	ENSG00000137825	-0.2909001955505459	[6]	[4,3]	-4	hSpCas9	positive selection	3846292
41494242	41494265	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGAAGAGCCCGCTGCCGGGAGG	ITPKA	ENSG00000137825	-0.025044016006337072	[4]	[3,4]	0	hSpCas9	positive selection	3846293
41501663	41501686	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGATCCTGAAGCGCTGCTCGG	ITPKA	ENSG00000137825	0.254494754306187	[6]	[6,6]	6	hSpCas9	positive selection	3846294
41501988	41502011	15	+	26780180	A375	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.227660908279225	[]	[]	0	hSpCas9	negative selection	3952316
41501483	41501506	15	+	26780180	A375	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	1.11289154023676	[]	[]	5	hSpCas9	negative selection	3952317
41501738	41501761	15	+	26780180	A375	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	1.89233822799204	[]	[]	9	hSpCas9	negative selection	3952318
41501712	41501735	15	+	26780180	A375	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.341250883202404	[]	[]	0	hSpCas9	negative selection	3952319
41502038	41502061	15	-	26780180	A375	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	1.3736958593308	[]	[]	7	hSpCas9	negative selection	3952320
41502828	41502851	15	+	26780180	A375	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	1.20754466723737	[]	[]	6	hSpCas9	negative selection	3952321
41501988	41502011	15	+	26780180	HT29	viability (GeCKOv2 library)	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.573815608533507	[]	[]	2	hSpCas9	negative selection	4060282
41501483	41501506	15	+	26780180	HT29	viability (GeCKOv2 library)	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	1.41955556363199	[]	[]	7	hSpCas9	negative selection	4060283
41501738	41501761	15	+	26780180	HT29	viability (GeCKOv2 library)	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	1.32509780034198	[]	[]	6	hSpCas9	negative selection	4060284
41501712	41501735	15	+	26780180	HT29	viability (GeCKOv2 library)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	1.16589807387844	[]	[]	5	hSpCas9	negative selection	4060285
41502038	41502061	15	-	26780180	HT29	viability (GeCKOv2 library)	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	1.3096936360131	[]	[]	6	hSpCas9	negative selection	4060286
41502828	41502851	15	+	26780180	HT29	viability (GeCKOv2 library)	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	1.47412650132079	[]	[]	7	hSpCas9	negative selection	4060287
41501988	41502011	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	-0.1326614363578555	[3]	[1,2]	-3	hSpCas9	positive selection	4145608
41501750	41501773	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTCGCGCTCCACCACGCCGTGG	ITPKA	ENSG00000137825	-0.14984177496152595	[3]	[2,1]	-4	hSpCas9	positive selection	4145610
41501712	41501735	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.4266594495014334	[3]	[2,3]	8	hSpCas9	positive selection	4145611
41502092	41502115	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCGCGTGCTCCTCCTCCGTGG	ITPKA	ENSG00000137825	-0.6154314293998401	[3]	[1,1]	-9	hSpCas9	positive selection	4145612
41501988	41502011	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.026603285594473558	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4209630
41501750	41501773	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTCGCGCTCCACCACGCCGTGG	ITPKA	ENSG00000137825	-0.17285515999684573	[3]	[0,2,2,0]	-2	hSpCas9	positive selection	4209632
41501712	41501735	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.2873738724544101	[3]	[0,2,1,0]	-4	hSpCas9	positive selection	4209633
41502092	41502115	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCGCGTGCTCCTCCTCCGTGG	ITPKA	ENSG00000137825	0.04425929440054033	[3]	[1,2,0,0]	0	hSpCas9	positive selection	4209634
41501738	41501761	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.039553239802451616	[2]	[1,2]	0	hSpCas9	positive selection	4277523
41501712	41501735	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.3237640733488139	[2]	[3,2]	6	hSpCas9	positive selection	4277524
41501988	41502011	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.8007337462295149	[4]	[8,3]	9	hSpCas9	positive selection	4277525
41501483	41501506	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.2664659967737576	[3]	[3,1]	-5	hSpCas9	positive selection	4341778
41502828	41502851	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.14994058631920187	[1]	[2,0]	-3	hSpCas9	positive selection	4341779
41502038	41502061	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.6067326686677584	[2]	[3,3]	9	hSpCas9	positive selection	4341780
41494103	41494125	15	-	27760321	OCIAML3	viability	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.6739547997289692	[1445,1187]	[1483,1832]	7	hSpCas9	negative selection	4410671
41494281	41494303	15	-	27760321	OCIAML3	viability	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.3170158443509801	[276,225]	[225,266]	3	hSpCas9	negative selection	4410672
41494368	41494390	15	-	27760321	OCIAML3	viability	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.4229663468231686	[839,707]	[372,549]	-4	hSpCas9	negative selection	4410673
41501513	41501535	15	-	27760321	OCIAML3	viability	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.28236049425316434	[225,202]	[165,100]	-3	hSpCas9	negative selection	4410674
41501632	41501654	15	+	27760321	OCIAML3	viability	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	-0.5944404112211119	[435,355]	[151,271]	-5	hSpCas9	negative selection	4410675
41494103	41494125	15	-	27760321	OCIAML2	viability	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.7573923492645165	[1445,1187]	[1646,1983]	8	hSpCas9	negative selection	4494134
41494281	41494303	15	-	27760321	OCIAML2	viability	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	-0.3329601733461891	[276,225]	[98,241]	-4	hSpCas9	negative selection	4494135
41494368	41494390	15	-	27760321	OCIAML2	viability	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	0.028821663611966697	[839,707]	[619,657]	0	hSpCas9	negative selection	4494136
41501513	41501535	15	-	27760321	OCIAML2	viability	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.11802273929594675	[225,202]	[138,186]	-1	hSpCas9	negative selection	4494137
41501632	41501654	15	+	27760321	OCIAML2	viability	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	0.0051260741770775275	[435,355]	[378,241]	0	hSpCas9	negative selection	4494138
41494103	41494125	15	-	27760321	MV411	viability	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.869479026704113	[1445,1187]	[1672,1440]	6	hSpCas9	negative selection	4577597
41494281	41494303	15	-	27760321	MV411	viability	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	-0.6614517983146511	[276,225]	[105,101]	-4	hSpCas9	negative selection	4577598
41494368	41494390	15	-	27760321	MV411	viability	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.5772742044619597	[839,707]	[408,238]	-4	hSpCas9	negative selection	4577599
41501513	41501535	15	-	27760321	MV411	viability	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.9300860931504782	[225,202]	[80,63]	-6	hSpCas9	negative selection	4577600
41501632	41501654	15	+	27760321	MV411	viability	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	0.17643099496072587	[435,355]	[336,228]	1	hSpCas9	negative selection	4577601
41494103	41494125	15	-	27760321	HL60	viability	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.5944487155403475	[1445,1187]	[1505,1733]	7	hSpCas9	negative selection	4661060
41494281	41494303	15	-	27760321	HL60	viability	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	-0.2896994359162204	[276,225]	[157,176]	-3	hSpCas9	negative selection	4661061
41494368	41494390	15	-	27760321	HL60	viability	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.2825055553514886	[839,707]	[447,591]	-3	hSpCas9	negative selection	4661062
41501513	41501535	15	-	27760321	HL60	viability	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	0.21796117432937578	[225,202]	[238,165]	2	hSpCas9	negative selection	4661063
41501632	41501654	15	+	27760321	HL60	viability	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	-0.6289665484099498	[435,355]	[228,185]	-6	hSpCas9	negative selection	4661064
41494103	41494125	15	-	27760321	HT1080	viability	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.9791360095755903	[1187,926]	[881,773]	5	hSpCas9	negative selection	4744523
41494281	41494303	15	-	27760321	HT1080	viability	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.1705758877972171	[225,176]	[76,104]	0	hSpCas9	negative selection	4744524
41494368	41494390	15	-	27760321	HT1080	viability	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-1.0065395038648144	[707,552]	[114,135]	-4	hSpCas9	negative selection	4744525
41501513	41501535	15	-	27760321	HT1080	viability	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	1.1768434199126958	[202,158]	[258,57]	6	hSpCas9	negative selection	4744526
41501632	41501654	15	+	27760321	HT1080	viability	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	1.074559473609032	[355,277]	[159,381]	6	hSpCas9	negative selection	4744527
41494103	41494125	15	-	27760321	HT29	viability after 7 days	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.43023694478437524	[1187,926]	[2202,1627,1718]	6	hSpCas9	negative selection	4827986
41494281	41494303	15	-	27760321	HT29	viability after 7 days	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.34192460350292364	[225,176]	[145,299,506]	5	hSpCas9	negative selection	4827987
41494368	41494390	15	-	27760321	HT29	viability after 7 days	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.24480415339813844	[707,552]	[864,614,599]	-4	hSpCas9	negative selection	4827988
41501513	41501535	15	-	27760321	HT29	viability after 7 days	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.21814137156090363	[202,158]	[193,263,142]	-3	hSpCas9	negative selection	4827989
41501632	41501654	15	+	27760321	HT29	viability after 7 days	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	-0.17759260988757605	[355,277]	[517,380,208]	-3	hSpCas9	negative selection	4827990
41494103	41494125	15	-	27760321	HT29	viability after 25 days	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	1.143525978747758	[1187,926]	[2272,3014,2750]	9	hSpCas9	negative selection	4911449
41494281	41494303	15	-	27760321	HT29	viability after 25 days	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.3956987752087899	[225,176]	[291,264,357]	4	hSpCas9	negative selection	4911450
41494368	41494390	15	-	27760321	HT29	viability after 25 days	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.10145912868211071	[707,552]	[550,656,829]	-1	hSpCas9	negative selection	4911451
41501513	41501535	15	-	27760321	HT29	viability after 25 days	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.09729608409763435	[202,158]	[115,264,204]	-1	hSpCas9	negative selection	4911452
41501632	41501654	15	+	27760321	HT29	viability after 25 days	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	0.4007183853559275	[355,277]	[339,398,729]	4	hSpCas9	negative selection	4911453
41494103	41494125	15	-	27760321	HT29	viability after 22 days	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	1.0670935244668265	[1187,926]	[2709,2418,2550]	9	hSpCas9	negative selection	4994912
41494281	41494303	15	-	27760321	HT29	viability after 22 days	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.42136501108164576	[225,176]	[123,310,507]	4	hSpCas9	negative selection	4994913
41494368	41494390	15	-	27760321	HT29	viability after 22 days	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	0.06923450865299796	[707,552]	[937,749,599]	0	hSpCas9	negative selection	4994914
41501513	41501535	15	-	27760321	HT29	viability after 22 days	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.42173355894559983	[202,158]	[93,261,113]	-4	hSpCas9	negative selection	4994915
41501632	41501654	15	+	27760321	HT29	viability after 22 days	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	0.23372214601542493	[355,277]	[317,528,448]	2	hSpCas9	negative selection	4994916
41494103	41494125	15	-	27760321	HT29	viability after 19 days	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.8994466576173064	[1187,926]	[2892,2296,1665]	8	hSpCas9	negative selection	5078375
41494281	41494303	15	-	27760321	HT29	viability after 19 days	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.8119293930822845	[225,176]	[238,435,516]	8	hSpCas9	negative selection	5078376
41494368	41494390	15	-	27760321	HT29	viability after 19 days	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	0.27729177736281274	[707,552]	[857,952,810]	2	hSpCas9	negative selection	5078377
41501513	41501535	15	-	27760321	HT29	viability after 19 days	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	0.30841753281911577	[202,158]	[280,83,400]	3	hSpCas9	negative selection	5078378
41501632	41501654	15	+	27760321	HT29	viability after 19 days	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	0.6175592802036146	[355,277]	[501,423,729]	6	hSpCas9	negative selection	5078379
41494103	41494125	15	-	27760321	HT29	viability after 16 days	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	1.1143762986657741	[1187,926]	[2933,2415,2372]	9	hSpCas9	negative selection	5161838
41494281	41494303	15	-	27760321	HT29	viability after 16 days	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.1283603375221387	[225,176]	[316,285,141]	1	hSpCas9	negative selection	5161839
41494368	41494390	15	-	27760321	HT29	viability after 16 days	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.07533396380604229	[707,552]	[752,838,419]	-1	hSpCas9	negative selection	5161840
41501513	41501535	15	-	27760321	HT29	viability after 16 days	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	0.4378242956800459	[202,158]	[203,327,282]	5	hSpCas9	negative selection	5161841
41501632	41501654	15	+	27760321	HT29	viability after 16 days	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	-0.14732960043629215	[355,277]	[238,166,550]	-1	hSpCas9	negative selection	5161842
41494103	41494125	15	-	27760321	HT29	viability after 13 days	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	1.0380741842402383	[1187,926]	[2953,2557,2071]	9	hSpCas9	negative selection	5245301
41494281	41494303	15	-	27760321	HT29	viability after 13 days	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.331462877646039	[225,176]	[195,276,402]	4	hSpCas9	negative selection	5245302
41494368	41494390	15	-	27760321	HT29	viability after 13 days	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.5352320338391436	[707,552]	[496,457,555]	-6	hSpCas9	negative selection	5245303
41501513	41501535	15	-	27760321	HT29	viability after 13 days	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.10417662510247283	[202,158]	[60,236,282]	-1	hSpCas9	negative selection	5245304
41501632	41501654	15	+	27760321	HT29	viability after 13 days	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	0.3634487121616698	[355,277]	[453,349,606]	4	hSpCas9	negative selection	5245305
41494103	41494125	15	-	27760321	HT29	viability after 10 days	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.7104634261566247	[1187,926]	[2224,2108,2145]	8	hSpCas9	negative selection	5328764
41494281	41494303	15	-	27760321	HT29	viability after 10 days	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	0.28463523927983847	[225,176]	[237,366,315]	4	hSpCas9	negative selection	5328765
41494368	41494390	15	-	27760321	HT29	viability after 10 days	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.47445626070354796	[707,552]	[585,602,512]	-5	hSpCas9	negative selection	5328766
41501513	41501535	15	-	27760321	HT29	viability after 10 days	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.18941250524891007	[202,158]	[195,85,306]	-2	hSpCas9	negative selection	5328767
41501632	41501654	15	+	27760321	HT29	viability after 10 days	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	0.3515519380417797	[355,277]	[686,423,403]	5	hSpCas9	negative selection	5328768
41494103	41494125	15	-	27760321	MOLM13	viability	ACCTGTCCCCCACGCCGCTTGG	ITPKA	ENSG00000137825	0.466878336058169	[1445,1187]	[1262,816]	3	hSpCas9	negative selection	5412227
41494281	41494303	15	-	27760321	MOLM13	viability	GACCGACGAGGTGGAAAGGCGG	ITPKA	ENSG00000137825	1.0732692545176026	[276,225]	[127,440]	7	hSpCas9	negative selection	5412228
41494368	41494390	15	-	27760321	MOLM13	viability	CTGCACGTTGCCGCGGCTCCGG	ITPKA	ENSG00000137825	-0.9269684226180201	[839,707]	[136,306]	-5	hSpCas9	negative selection	5412229
41501513	41501535	15	-	27760321	MOLM13	viability	GGCGTAGCGCTTCTTGAAAGGG	ITPKA	ENSG00000137825	-0.3049359130058329	[225,202]	[119,78]	-2	hSpCas9	negative selection	5412230
41501632	41501654	15	+	27760321	MOLM13	viability	CAGGGAGTTTTAAGGCGGCGGG	ITPKA	ENSG00000137825	-0.08713564804853388	[435,355]	[97,303]	0	hSpCas9	negative selection	5412231
41494227	41494250	15	+	27661255	K562	viability	GCGGGAGAGGGACTGCCTCCCGG	ITPKA	ENSG00000137825	-0.013932467266909332	[393,380]	[316,297]	0	dCas9-KRAB	negative selection	5487487
41494320	41494343	15	+	27661255	K562	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-0.018503652559914652	[673,722]	[662,453]	0	dCas9-KRAB	negative selection	5487488
41493937	41493960	15	-	27661255	K562	viability	GCCATGCCCGTTGGGCCCCCGGG	ITPKA	ENSG00000137825	-0.09096840145438123	[415,531]	[381,329]	-3	dCas9-KRAB	negative selection	5487489
41494242	41494265	15	-	27661255	K562	viability	GCGAAGAGCCCGCTGCCGGGAGG	ITPKA	ENSG00000137825	0.1980535785686186	[93,157]	[135,95]	6	dCas9-KRAB	negative selection	5487490
41494276	41494299	15	-	27661255	K562	viability	GACGAGGTGGAAAGGCGGCGCGG	ITPKA	ENSG00000137825	0.13343274120325066	[492,448]	[414,411]	4	dCas9-KRAB	negative selection	5487491
41494292	41494315	15	-	27661255	K562	viability	GCCAGTGGAGGAGACCGACGAGG	ITPKA	ENSG00000137825	0.16784881307999672	[620,384]	[418,485]	6	dCas9-KRAB	negative selection	5487492
41501738	41501761	15	+	27260156	BXPC3	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.05156906291721705	[428]	[423,381,388,550]	-1	hSpCas9	negative selection	5549983
41501712	41501735	15	+	27260156	BXPC3	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.008839953023126013	[389]	[355,393,382,525]	0	hSpCas9	negative selection	5549984
41501988	41502011	15	+	27260156	BXPC3	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.411727546393688	[1063]	[1379,1418,1496,1648]	8	hSpCas9	negative selection	5549985
41501483	41501506	15	+	27260156	BXPC3	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.3762638017302574	[957]	[672,926,649,838]	-7	hSpCas9	negative selection	5614238
41502828	41502851	15	+	27260156	BXPC3	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.5855190155646537	[172]	[121,117,114,126]	-8	hSpCas9	negative selection	5614239
41502038	41502061	15	-	27260156	BXPC3	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.044701422121552675	[420]	[346,403,464,508]	-1	hSpCas9	negative selection	5614240
41501738	41501761	15	+	27260156	A673	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.051099809545317024	[428]	[619,486,476,562]	1	hSpCas9	negative selection	5671234
41501712	41501735	15	+	27260156	A673	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.03666056132119089	[389]	[458,470,442,451]	-1	hSpCas9	negative selection	5671235
41501988	41502011	15	+	27260156	A673	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.16275073939806406	[1063]	[1415,1366,1387,1553]	4	hSpCas9	negative selection	5671236
41501483	41501506	15	+	27260156	A673	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.27835564289615333	[957]	[1009,928,924,934]	-6	hSpCas9	negative selection	5735489
41502828	41502851	15	+	27260156	A673	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.18336476431686766	[172]	[194,176,264,89]	-4	hSpCas9	negative selection	5735490
41502038	41502061	15	-	27260156	A673	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.009133595233947023	[420]	[631,466,479,441]	0	hSpCas9	negative selection	5735491
41501738	41501761	15	+	27260156	A375	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.508001848571217	[428]	[384,432,290,314]	-6	hSpCas9	negative selection	5792485
41501712	41501735	15	+	27260156	A375	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.2260074548990209	[389]	[519,610,551,464]	3	hSpCas9	negative selection	5792486
41501988	41502011	15	+	27260156	A375	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.13119079678557233	[1063]	[1318,1398,1430,1301]	2	hSpCas9	negative selection	5792487
41501483	41501506	15	+	27260156	A375	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.31459833389488445	[957]	[831,1101,835,857]	-4	hSpCas9	negative selection	5856740
41502828	41502851	15	+	27260156	A375	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.5031485884528744	[172]	[261,327,411,162]	7	hSpCas9	negative selection	5856741
41502038	41502061	15	-	27260156	A375	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.5501894381688021	[420]	[818,681,986,420]	7	hSpCas9	negative selection	5856742
41501738	41501761	15	+	27260156	COLO741	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.09738250861159226	[428]	[719,462,585]	2	hSpCas9	negative selection	5913736
41501712	41501735	15	+	27260156	COLO741	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.2757164607017329	[389]	[348,373,498]	-5	hSpCas9	negative selection	5913737
41501988	41502011	15	+	27260156	COLO741	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.2757280327301084	[1063]	[1840,1562,1552]	6	hSpCas9	negative selection	5913738
41501483	41501506	15	+	27260156	COLO741	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.04558453507353377	[957]	[1157,1376,1029]	-1	hSpCas9	negative selection	5977991
41502828	41502851	15	+	27260156	COLO741	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.1703964575171868	[172]	[230,126,230]	-4	hSpCas9	negative selection	5977992
41502038	41502061	15	-	27260156	COLO741	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.19080736842079846	[420]	[726,579,547]	4	hSpCas9	negative selection	5977993
41501738	41501761	15	+	27260156	CAL120	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.27676277291227	[428]	[746,559,647]	4	hSpCas9	negative selection	6034987
41501712	41501735	15	+	27260156	CAL120	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.274766886975597	[389]	[652,527,589]	4	hSpCas9	negative selection	6034988
41501988	41502011	15	+	27260156	CAL120	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.4431281930014137	[1063]	[2108,1761,1578]	6	hSpCas9	negative selection	6034989
41501483	41501506	15	+	27260156	CAL120	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.5360165816171397	[957]	[1021,805,670]	-6	hSpCas9	negative selection	6099242
41502828	41502851	15	+	27260156	CAL120	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.3614494089709499	[172]	[420,246,184]	5	hSpCas9	negative selection	6099243
41502038	41502061	15	-	27260156	CAL120	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.2349924552428881	[420]	[531,353,461]	-3	hSpCas9	negative selection	6099244
41501738	41501761	15	+	27260156	CADOES1	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.2586552442960907	[428]	[282,326,291,435]	-4	hSpCas9	negative selection	6156238
41501712	41501735	15	+	27260156	CADOES1	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.012202416616996115	[389]	[391,358,393,290]	0	hSpCas9	negative selection	6156239
41501988	41502011	15	+	27260156	CADOES1	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.22921084696356075	[1063]	[1097,1151,1103,1290]	4	hSpCas9	negative selection	6156240
41501483	41501506	15	+	27260156	CADOES1	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.6762699016770783	[957]	[566,482,649,528]	-8	hSpCas9	negative selection	6220493
41502828	41502851	15	+	27260156	CADOES1	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.4506342045462155	[172]	[87,93,118,171]	-7	hSpCas9	negative selection	6220494
41502038	41502061	15	-	27260156	CADOES1	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.4105231455990862	[420]	[399,433,697,550]	6	hSpCas9	negative selection	6220495
41501738	41501761	15	+	27260156	EWS502	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.3721740803998757	[428]	[309,289,378,437]	-6	hSpCas9	negative selection	6277489
41501712	41501735	15	+	27260156	EWS502	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.36357943361091843	[389]	[294,416,299,265]	-6	hSpCas9	negative selection	6277490
41501988	41502011	15	+	27260156	EWS502	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.14097721647844175	[1063]	[1012,990,1252,1785]	2	hSpCas9	negative selection	6277491
41501483	41501506	15	+	27260156	EWS502	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.15311475281128617	[957]	[963,796,840,1051]	-3	hSpCas9	negative selection	6341744
41502828	41502851	15	+	27260156	EWS502	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.29628257158598337	[172]	[179,193,139,70]	-5	hSpCas9	negative selection	6341745
41502038	41502061	15	-	27260156	EWS502	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.3530478660429963	[420]	[531,392,440,946]	6	hSpCas9	negative selection	6341746
41501738	41501761	15	+	27260156	EW8	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.3688209517428764	[428]	[291,232,247,308]	-6	hSpCas9	negative selection	6398740
41501712	41501735	15	+	27260156	EW8	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.09190422350833594	[389]	[296,414,411,205]	1	hSpCas9	negative selection	6398741
41501988	41502011	15	+	27260156	EW8	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.014930040324677263	[1063]	[909,951,669,988]	0	hSpCas9	negative selection	6398742
41501483	41501506	15	+	27260156	EW8	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.43945218079589365	[957]	[819,541,422,555]	-7	hSpCas9	negative selection	6462995
41502828	41502851	15	+	27260156	EW8	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.3008338366744363	[172]	[146,52,102,156]	-5	hSpCas9	negative selection	6462996
41502038	41502061	15	-	27260156	EW8	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.3215789188032583	[420]	[382,456,369,498]	6	hSpCas9	negative selection	6462997
41501738	41501761	15	+	27260156	CORL105	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.018896031252311818	[428]	[564,415,573,443]	0	hSpCas9	negative selection	6519991
41501712	41501735	15	+	27260156	CORL105	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.18478479151844676	[389]	[526,543,602,414]	3	hSpCas9	negative selection	6519992
41501988	41502011	15	+	27260156	CORL105	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.5746924864224201	[1063]	[1952,1816,2046,1637]	9	hSpCas9	negative selection	6519993
41501483	41501506	15	+	27260156	CORL105	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.5953515401036736	[957]	[765,723,659,806]	-8	hSpCas9	negative selection	6584246
41502828	41502851	15	+	27260156	CORL105	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.007543593437714158	[172]	[220,152,261,180]	0	hSpCas9	negative selection	6584247
41502038	41502061	15	-	27260156	CORL105	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.12015914911760875	[420]	[477,448,556,660]	2	hSpCas9	negative selection	6584248
41501738	41501761	15	+	27260156	HS294T	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.23219916035661203	[428]	[105,129,141,199]	-3	hSpCas9	negative selection	6641242
41501712	41501735	15	+	27260156	HS294T	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.10467464731556964	[389]	[189,84,114,172]	-1	hSpCas9	negative selection	6641243
41501988	41502011	15	+	27260156	HS294T	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.34804584384886494	[1063]	[444,509,666,469]	5	hSpCas9	negative selection	6641244
41501483	41501506	15	+	27260156	HS294T	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.4248420866319287	[957]	[232,226,270,397]	-6	hSpCas9	negative selection	6705497
41502828	41502851	15	+	27260156	HS294T	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.6847493269468283	[172]	[41,36,37,50]	-7	hSpCas9	negative selection	6705498
41502038	41502061	15	-	27260156	HS294T	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.1462412851060927	[420]	[197,128,116,137]	-2	hSpCas9	negative selection	6705499
41501738	41501761	15	+	27260156	HCC44	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.32755838733452897	[428]	[466,291,495,329]	-5	hSpCas9	negative selection	6762493
41501712	41501735	15	+	27260156	HCC44	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.5418250446104746	[389]	[509,489,809,786]	8	hSpCas9	negative selection	6762494
41501988	41502011	15	+	27260156	HCC44	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.18550281285343884	[1063]	[1433,958,1572,1588]	3	hSpCas9	negative selection	6762495
41501483	41501506	15	+	27260156	HCC44	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.39561751102812437	[957]	[1121,498,786,942]	-6	hSpCas9	negative selection	6826748
41502828	41502851	15	+	27260156	HCC44	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.09350586365948277	[172]	[247,136,334,54]	-1	hSpCas9	negative selection	6826749
41502038	41502061	15	-	27260156	HCC44	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.23913916897439128	[420]	[474,410,747,651]	4	hSpCas9	negative selection	6826750
41501738	41501761	15	+	27260156	G402	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.9632042379078203	[428]	[443,267,281,111]	-8	hSpCas9	negative selection	6883744
41501712	41501735	15	+	27260156	G402	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.08017175995988968	[389]	[367,402,519,684]	1	hSpCas9	negative selection	6883745
41501988	41502011	15	+	27260156	G402	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.14641902827730746	[1063]	[1570,1244,1634,1305]	1	hSpCas9	negative selection	6883746
41501483	41501506	15	+	27260156	G402	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.7297756123334491	[957]	[665,567,944,627]	-7	hSpCas9	negative selection	6947999
41502828	41502851	15	+	27260156	G402	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.44345070452074464	[172]	[238,306,279,313]	5	hSpCas9	negative selection	6948000
41502038	41502061	15	-	27260156	G402	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.3032685177507992	[420]	[535,645,626,706]	4	hSpCas9	negative selection	6948001
41501738	41501761	15	+	27260156	L33	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.017928542850195753	[428]	[409,173,333,372]	0	hSpCas9	negative selection	7004995
41501712	41501735	15	+	27260156	L33	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.04305025101150456	[389]	[408,144,286,294]	-1	hSpCas9	negative selection	7004996
41501988	41502011	15	+	27260156	L33	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.46460304435379474	[1063]	[1401,621,795,1684]	8	hSpCas9	negative selection	7004997
41501483	41501506	15	+	27260156	L33	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.3514038573021592	[957]	[679,283,631,628]	-7	hSpCas9	negative selection	7069250
41502828	41502851	15	+	27260156	L33	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.076974766851309	[172]	[168,103,63,204]	1	hSpCas9	negative selection	7069251
41502038	41502061	15	-	27260156	L33	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.059654983569297826	[420]	[376,171,310,325]	-1	hSpCas9	negative selection	7069252
41501738	41501761	15	+	27260156	K562	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.2779587642903538	[428]	[211,603,239,216]	-3	hSpCas9	negative selection	7126246
41501712	41501735	15	+	27260156	K562	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.045799898248469695	[389]	[256,341,232,483]	0	hSpCas9	negative selection	7126247
41501988	41502011	15	+	27260156	K562	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.17367910681198917	[1063]	[1087,831,1069,1234]	2	hSpCas9	negative selection	7126248
41501483	41501506	15	+	27260156	K562	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.45092722253266426	[957]	[644,479,896,474]	-5	hSpCas9	negative selection	7190501
41502828	41502851	15	+	27260156	K562	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.1677050398795541	[172]	[118,292,162,121]	2	hSpCas9	negative selection	7190502
41502038	41502061	15	-	27260156	K562	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.32480184872272344	[420]	[533,595,284,466]	4	hSpCas9	negative selection	7190503
41501738	41501761	15	+	27260156	HT29	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.005383267250206852	[428]	[512,642,520,419]	0	hSpCas9	negative selection	7247497
41501712	41501735	15	+	27260156	HT29	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.07463946540547844	[389]	[572,420,302,500]	-1	hSpCas9	negative selection	7247498
41501988	41502011	15	+	27260156	HT29	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.393814029895321	[1063]	[1950,1969,1515,1424]	7	hSpCas9	negative selection	7247499
41501483	41501506	15	+	27260156	HT29	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.07987222602768262	[957]	[860,1373,1101,1070]	-2	hSpCas9	negative selection	7311752
41502828	41502851	15	+	27260156	HT29	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.005580846794633665	[172]	[147,362,154,187]	0	hSpCas9	negative selection	7311753
41502038	41502061	15	-	27260156	HT29	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.19091128065337223	[420]	[457,782,605,502]	4	hSpCas9	negative selection	7311754
41501738	41501761	15	+	27260156	MHHES1	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.2920729492981169	[428]	[358,435,439,345]	-5	hSpCas9	negative selection	7368748
41501712	41501735	15	+	27260156	MHHES1	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.08326314287450515	[389]	[786,359,500,275]	1	hSpCas9	negative selection	7368749
41501988	41502011	15	+	27260156	MHHES1	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.1885076823164371	[1063]	[1431,1538,1509,1050]	3	hSpCas9	negative selection	7368750
41501483	41501506	15	+	27260156	MHHES1	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.29280930796215077	[957]	[922,894,1064,675]	-5	hSpCas9	negative selection	7433003
41502828	41502851	15	+	27260156	MHHES1	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.24497906060584484	[172]	[195,185,140,141]	-4	hSpCas9	negative selection	7433004
41502038	41502061	15	-	27260156	MHHES1	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.6175468688035686	[420]	[884,338,1261,454]	9	hSpCas9	negative selection	7433005
41501738	41501761	15	+	27260156	MEWO	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.21622098965356434	[428]	[517,398,491]	5	hSpCas9	negative selection	7489999
41501712	41501735	15	+	27260156	MEWO	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.20189087860593924	[389]	[386,339,237]	-4	hSpCas9	negative selection	7490000
41501988	41502011	15	+	27260156	MEWO	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.35184997056321143	[1063]	[1570,1081,1216]	7	hSpCas9	negative selection	7490001
41501483	41501506	15	+	27260156	MEWO	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.2620629835848347	[957]	[917,555,801]	-5	hSpCas9	negative selection	7554254
41502828	41502851	15	+	27260156	MEWO	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.020171781525380572	[172]	[212,184,90]	0	hSpCas9	negative selection	7554255
41502038	41502061	15	-	27260156	MEWO	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.09246124945323592	[420]	[352,368,382]	-2	hSpCas9	negative selection	7554256
41501738	41501761	15	+	27260156	LNCAPCLONEFGC	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.3836817424677918	[428]	[373,192,373,266]	-5	hSpCas9	negative selection	7611250
41501712	41501735	15	+	27260156	LNCAPCLONEFGC	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.4535149297578962	[389]	[383,380,668,536]	7	hSpCas9	negative selection	7611251
41501988	41502011	15	+	27260156	LNCAPCLONEFGC	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.23580526640239374	[1063]	[910,1186,1491,1002]	3	hSpCas9	negative selection	7611252
41501483	41501506	15	+	27260156	LNCAPCLONEFGC	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.30855100978857475	[957]	[882,588,678,651]	-5	hSpCas9	negative selection	7675505
41502828	41502851	15	+	27260156	LNCAPCLONEFGC	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.2646117340992855	[172]	[195,129,237,199]	4	hSpCas9	negative selection	7675506
41502038	41502061	15	-	27260156	LNCAPCLONEFGC	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.3986800363779489	[420]	[426,393,796,444]	6	hSpCas9	negative selection	7675507
41501738	41501761	15	+	27260156	PANC0327	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.16695911078987136	[428]	[314,276,488,282]	-2	hSpCas9	negative selection	7732501
41501712	41501735	15	+	27260156	PANC0327	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.09645906209185373	[389]	[343,265,502,379]	1	hSpCas9	negative selection	7732502
41501988	41502011	15	+	27260156	PANC0327	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.48844097993537083	[1063]	[1217,970,2085,1066]	7	hSpCas9	negative selection	7732503
41501483	41501506	15	+	27260156	PANC0327	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.3182434287329988	[957]	[728,564,733,720]	-5	hSpCas9	negative selection	7796756
41502828	41502851	15	+	27260156	PANC0327	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.4844174521240576	[172]	[93,71,151,124]	-6	hSpCas9	negative selection	7796757
41502038	41502061	15	-	27260156	PANC0327	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.09467617049573612	[420]	[352,295,359,398]	-1	hSpCas9	negative selection	7796758
41501738	41501761	15	+	27260156	NCIH2009	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.16720957236675965	[428]	[571,478,557]	-2	hSpCas9	negative selection	7853752
41501712	41501735	15	+	27260156	NCIH2009	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.3135401421067084	[389]	[982,665,441]	4	hSpCas9	negative selection	7853753
41501988	41502011	15	+	27260156	NCIH2009	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.41629424894758005	[1063]	[2254,1967,1778]	6	hSpCas9	negative selection	7853754
41501483	41501506	15	+	27260156	NCIH2009	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.606839438098149	[957]	[1162,841,686]	-6	hSpCas9	negative selection	7918007
41502828	41502851	15	+	27260156	NCIH2009	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.3237582563292114	[172]	[360,94,157]	-4	hSpCas9	negative selection	7918008
41502038	41502061	15	-	27260156	NCIH2009	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.032468168002342895	[420]	[635,631,541]	0	hSpCas9	negative selection	7918009
41501738	41501761	15	+	27260156	NCIH1373	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.0008563191220328781	[428]	[720,440,517,70]	0	hSpCas9	negative selection	7975003
41501712	41501735	15	+	27260156	NCIH1373	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.15377947916836984	[389]	[777,535,376,73]	1	hSpCas9	negative selection	7975004
41501988	41502011	15	+	27260156	NCIH1373	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.4769401553134598	[1063]	[1479,1526,1359,602]	5	hSpCas9	negative selection	7975005
41501483	41501506	15	+	27260156	NCIH1373	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-1.1264907791106125	[957]	[764,255,481,139]	-8	hSpCas9	negative selection	8039258
41502828	41502851	15	+	27260156	NCIH1373	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.5702305774662235	[172]	[440,230,181,86]	5	hSpCas9	negative selection	8039259
41502038	41502061	15	-	27260156	NCIH1373	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.7037547380439642	[420]	[721,784,994,141]	7	hSpCas9	negative selection	8039260
41501738	41501761	15	+	27260156	PATU8902	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.6904612907946812	[428]	[348,155,483,470]	-6	hSpCas9	negative selection	8096254
41501712	41501735	15	+	27260156	PATU8902	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.7247754462639898	[389]	[1243,1243,373,847]	7	hSpCas9	negative selection	8096255
41501988	41502011	15	+	27260156	PATU8902	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.6263769841365143	[1063]	[2329,2689,1872,2354]	6	hSpCas9	negative selection	8096256
41501483	41501506	15	+	27260156	PATU8902	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.6004841476622136	[957]	[683,1170,584,1189]	-5	hSpCas9	negative selection	8160509
41502828	41502851	15	+	27260156	PATU8902	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.5256740984955879	[172]	[581,445,178,200]	5	hSpCas9	negative selection	8160510
41502038	41502061	15	-	27260156	PATU8902	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.7228409125634381	[420]	[643,630,608,2225]	7	hSpCas9	negative selection	8160511
41501738	41501761	15	+	27260156	PANC1	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.058054105991470206	[428]	[350,266,502,283]	-1	hSpCas9	negative selection	8217505
41501712	41501735	15	+	27260156	PANC1	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.44376043922148944	[389]	[368,586,441,446]	7	hSpCas9	negative selection	8217506
41501988	41502011	15	+	27260156	PANC1	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.652101802285675	[1063]	[1340,2065,1274,1206]	9	hSpCas9	negative selection	8217507
41501483	41501506	15	+	27260156	PANC1	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	0.09789653006995258	[957]	[736,852,1092,831]	1	hSpCas9	negative selection	8281760
41502828	41502851	15	+	27260156	PANC1	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.09663494522194038	[172]	[176,128,112,199]	1	hSpCas9	negative selection	8281761
41502038	41502061	15	-	27260156	PANC1	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.2693672996895668	[420]	[392,771,420,250]	4	hSpCas9	negative selection	8281762
41501738	41501761	15	+	27260156	PANC0813	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.39463584642794064	[428]	[328,537,344,318]	-6	hSpCas9	negative selection	8338756
41501712	41501735	15	+	27260156	PANC0813	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.17519697354072467	[389]	[382,342,341,543]	-3	hSpCas9	negative selection	8338757
41501988	41502011	15	+	27260156	PANC0813	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.405048408134546	[1063]	[1757,1809,1553,1511]	6	hSpCas9	negative selection	8338758
41501483	41501506	15	+	27260156	PANC0813	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.543662923161716	[957]	[772,652,950,713]	-7	hSpCas9	negative selection	8403011
41502828	41502851	15	+	27260156	PANC0813	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.39919885256964105	[172]	[92,231,125,158]	-6	hSpCas9	negative selection	8403012
41502038	41502061	15	-	27260156	PANC0813	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.3185966310392784	[420]	[462,337,485,309]	-5	hSpCas9	negative selection	8403013
41501738	41501761	15	+	27260156	RDES	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.45184341863559413	[428]	[302,312,426,416]	-6	hSpCas9	negative selection	8460007
41501712	41501735	15	+	27260156	RDES	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.16575993466270028	[389]	[327,565,485,675]	2	hSpCas9	negative selection	8460008
41501988	41502011	15	+	27260156	RDES	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.09349063125122159	[1063]	[1071,1426,1088,1680]	1	hSpCas9	negative selection	8460009
41501483	41501506	15	+	27260156	RDES	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.5709880187511376	[957]	[635,607,933,820]	-7	hSpCas9	negative selection	8524262
41502828	41502851	15	+	27260156	RDES	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.15240794049133344	[172]	[225,208,189,255]	2	hSpCas9	negative selection	8524263
41502038	41502061	15	-	27260156	RDES	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.4236405478042822	[420]	[480,569,757,848]	6	hSpCas9	negative selection	8524264
41501738	41501761	15	+	27260156	PC3	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.28091272704272097	[428]	[414,420,914,467]	6	hSpCas9	negative selection	8581258
41501712	41501735	15	+	27260156	PC3	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.12481783026014157	[389]	[293,351,593,542]	3	hSpCas9	negative selection	8581259
41501988	41502011	15	+	27260156	PC3	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.05706576874209679	[1063]	[772,1085,1906,981]	1	hSpCas9	negative selection	8581260
41501483	41501506	15	+	27260156	PC3	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.2553500489928847	[957]	[418,1018,1249,771]	-5	hSpCas9	negative selection	8645513
41502828	41502851	15	+	27260156	PC3	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.3800196205754427	[172]	[118,84,293,83]	-7	hSpCas9	negative selection	8645514
41502038	41502061	15	-	27260156	PC3	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.03405761340796368	[420]	[302,390,642,393]	0	hSpCas9	negative selection	8645515
41501738	41501761	15	+	27260156	PATU8988T	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.019771542824929378	[428]	[346,333,430,572]	0	hSpCas9	negative selection	8702509
41501712	41501735	15	+	27260156	PATU8988T	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.03413172347092358	[389]	[437,465,278,367]	0	hSpCas9	negative selection	8702510
41501988	41502011	15	+	27260156	PATU8988T	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.43041332970036095	[1063]	[1161,1509,1582,1287]	7	hSpCas9	negative selection	8702511
41501483	41501506	15	+	27260156	PATU8988T	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.3492903634924597	[957]	[589,748,723,855]	-5	hSpCas9	negative selection	8766764
41502828	41502851	15	+	27260156	PATU8988T	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.26655453878925917	[172]	[156,128,260,253]	4	hSpCas9	negative selection	8766765
41502038	41502061	15	-	27260156	PATU8988T	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.08460267289872872	[420]	[353,317,462,392]	-1	hSpCas9	negative selection	8766766
41501738	41501761	15	+	27260156	T47D	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.04006825338292497	[428]	[496,438,458,555]	-1	hSpCas9	negative selection	8823760
41501712	41501735	15	+	27260156	T47D	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.02448208611356467	[389]	[408,449,452,474]	0	hSpCas9	negative selection	8823761
41501988	41502011	15	+	27260156	T47D	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.14688298236591013	[1063]	[1231,1349,1409,1501]	3	hSpCas9	negative selection	8823762
41501483	41501506	15	+	27260156	T47D	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.5917477135614231	[957]	[676,729,720,837]	-8	hSpCas9	negative selection	8888015
41502828	41502851	15	+	27260156	T47D	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.1256420990229712	[172]	[234,163,163,177]	-3	hSpCas9	negative selection	8888016
41502038	41502061	15	-	27260156	T47D	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.04180930213816858	[420]	[614,351,443,626]	0	hSpCas9	negative selection	8888017
41501738	41501761	15	+	27260156	SU8686	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.2729644654661832	[428]	[435,312,287,363]	-4	hSpCas9	negative selection	8945011
41501712	41501735	15	+	27260156	SU8686	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.1900113358469035	[389]	[383,295,596,527]	3	hSpCas9	negative selection	8945012
41501988	41502011	15	+	27260156	SU8686	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.44237192956558524	[1063]	[1382,1421,1435,1499]	7	hSpCas9	negative selection	8945013
41501483	41501506	15	+	27260156	SU8686	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.45327489346991934	[957]	[564,699,674,871]	-6	hSpCas9	negative selection	9009266
41502828	41502851	15	+	27260156	SU8686	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.2926623678769462	[172]	[91,72,246,168]	-5	hSpCas9	negative selection	9009267
41502038	41502061	15	-	27260156	SU8686	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	-0.08614943806436123	[420]	[339,400,337,513]	-1	hSpCas9	negative selection	9009268
41501738	41501761	15	+	27260156	SKES1	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.07428226264289914	[428]	[401,560,330,352]	-2	hSpCas9	negative selection	9066262
41501712	41501735	15	+	27260156	SKES1	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.08492511673154429	[389]	[512,468,370,324]	1	hSpCas9	negative selection	9066263
41501988	41502011	15	+	27260156	SKES1	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.33597844411700817	[1063]	[1567,1217,1206,1366]	7	hSpCas9	negative selection	9066264
41501483	41501506	15	+	27260156	SKES1	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.48792541661725897	[957]	[919,774,559,527]	-8	hSpCas9	negative selection	9130517
41502828	41502851	15	+	27260156	SKES1	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.05595826039853802	[172]	[201,115,196,147]	-1	hSpCas9	negative selection	9130518
41502038	41502061	15	-	27260156	SKES1	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.11634160846207786	[420]	[388,521,531,379]	2	hSpCas9	negative selection	9130519
41501738	41501761	15	+	27260156	TOV112D	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.5022184722563497	[428]	[515,894,440,642]	8	hSpCas9	negative selection	9187513
41501712	41501735	15	+	27260156	TOV112D	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	0.3069256612402881	[389]	[558,332,582,427]	6	hSpCas9	negative selection	9187514
41501988	41502011	15	+	27260156	TOV112D	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.15925655382255632	[1063]	[991,1664,1107,1095]	3	hSpCas9	negative selection	9187515
41501483	41501506	15	+	27260156	TOV112D	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.3611304219891346	[957]	[731,809,637,818]	-6	hSpCas9	negative selection	9251768
41502828	41502851	15	+	27260156	TOV112D	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	0.03085931653118168	[172]	[158,157,331,55]	0	hSpCas9	negative selection	9251769
41502038	41502061	15	-	27260156	TOV112D	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.057307245595254366	[420]	[616,440,352,360]	1	hSpCas9	negative selection	9251770
41501738	41501761	15	+	27260156	TC71	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	-0.035070307311095644	[428]	[446,477,383,490]	-1	hSpCas9	negative selection	9308764
41501712	41501735	15	+	27260156	TC71	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.033792105911519266	[389]	[426,318,424,464]	-1	hSpCas9	negative selection	9308765
41501988	41502011	15	+	27260156	TC71	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	0.3793641725145174	[1063]	[1444,1467,1360,1676]	8	hSpCas9	negative selection	9308766
41501483	41501506	15	+	27260156	TC71	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.38247429127310395	[957]	[729,832,759,832]	-8	hSpCas9	negative selection	9373019
41502828	41502851	15	+	27260156	TC71	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.32614042992212733	[172]	[165,136,105,185]	-7	hSpCas9	negative selection	9373020
41502038	41502061	15	-	27260156	TC71	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.0796574229618551	[420]	[356,494,477,586]	2	hSpCas9	negative selection	9373021
41501738	41501761	15	+	27260156	TC32	viability	CGTGCCTGCCTTCCACGGCGTGG	ITPKA	ENSG00000137825	0.20711341004757372	[428]	[377,522,444,469]	4	hSpCas9	negative selection	9430015
41501712	41501735	15	+	27260156	TC32	viability	CTGATGGCTGACGCGCTGCGCGG	ITPKA	ENSG00000137825	-0.02715571013423157	[389]	[386,197,517,402]	0	hSpCas9	negative selection	9430016
41501988	41502011	15	+	27260156	TC32	viability	CCCCCACAGGACTTACCTAGAGG	ITPKA	ENSG00000137825	-0.00894576944187997	[1063]	[915,771,1213,1153]	0	hSpCas9	negative selection	9430017
41501483	41501506	15	+	27260156	TC32	viability	CCGGACCATGGTCAATCTGCCGG	ITPKA	ENSG00000137825	-0.39920536730916667	[957]	[580,505,998,742]	-6	hSpCas9	negative selection	9494270
41502828	41502851	15	+	27260156	TC32	viability	TGGAGGTATCCGAGTTCTTCAGG	ITPKA	ENSG00000137825	-0.1815706494628977	[172]	[97,117,174,197]	-3	hSpCas9	negative selection	9494271
41502038	41502061	15	-	27260156	TC32	viability	GTACATGTCCTTCCGCAGCTTGG	ITPKA	ENSG00000137825	0.06290558498048887	[420]	[470,235,580,430]	1	hSpCas9	negative selection	9494272
41494155	41494178	15	-	27869803	HPAFII	viability after 27 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.7992414058755128	[203]	[400,7,NaN]	6	hSpCas9	negative selection	9553545
41501488	41501511	15	-	27869803	HPAFII	viability after 27 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-0.7034625423317931	[106]	[27,39,NaN]	-5	hSpCas9	negative selection	9553546
41501641	41501664	15	+	27869803	HPAFII	viability after 27 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.4962819747225031	[145]	[98,115,NaN]	4	hSpCas9	negative selection	9553547
41502081	41502104	15	+	27869803	HPAFII	viability after 27 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.9186809614019231	[286]	[105,57,NaN]	-6	hSpCas9	negative selection	9553548
41502434	41502457	15	+	27869803	HPAFII	viability after 27 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.4547267381309389	[172]	[97,39,NaN]	-3	hSpCas9	negative selection	9553549
41502802	41502825	15	-	27869803	HPAFII	viability after 27 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-2.2494514335608686	[73]	[11,4,NaN]	-8	hSpCas9	negative selection	9553550
41494155	41494178	15	-	27869803	HPAFII	viability after 15 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.5144984566381813	[203]	[565,155,NaN]	6	hSpCas9	negative selection	9635994
41501488	41501511	15	-	27869803	HPAFII	viability after 15 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-1.098932883676713	[106]	[94,27,NaN]	-8	hSpCas9	negative selection	9635995
41501641	41501664	15	+	27869803	HPAFII	viability after 15 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	-0.4369609245453282	[145]	[200,62,NaN]	-5	hSpCas9	negative selection	9635996
41502081	41502104	15	+	27869803	HPAFII	viability after 15 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.5324613500471161	[286]	[240,195,NaN]	-5	hSpCas9	negative selection	9635997
41502434	41502457	15	+	27869803	HPAFII	viability after 15 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-1.2347572347539386	[172]	[115,55,NaN]	-8	hSpCas9	negative selection	9635998
41502802	41502825	15	-	27869803	HPAFII	viability after 15 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-1.3653287512951477	[73]	[57,13,NaN]	-8	hSpCas9	negative selection	9635999
41494155	41494178	15	-	27869803	ASPC1	viability after 36 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-1.368700569198686	[476]	[47,40,93]	-8	hSpCas9	negative selection	9718443
41501488	41501511	15	-	27869803	ASPC1	viability after 36 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-0.9242607234357236	[462]	[52,89,102]	-7	hSpCas9	negative selection	9718444
41501641	41501664	15	+	27869803	ASPC1	viability after 36 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.5064563339194618	[353]	[236,140,157]	5	hSpCas9	negative selection	9718445
41502081	41502104	15	+	27869803	ASPC1	viability after 36 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-0.5366225557963942	[607]	[144,252,60]	-5	hSpCas9	negative selection	9718446
41502434	41502457	15	+	27869803	ASPC1	viability after 36 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-1.8978286138316152	[406]	[23,48,38]	-9	hSpCas9	negative selection	9718447
41502802	41502825	15	-	27869803	ASPC1	viability after 36 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	0.09537825188402982	[180]	[152,65,7]	0	hSpCas9	negative selection	9718448
41494155	41494178	15	-	27869803	PATU8988S	viability after 35 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	-0.2230696761499107	[363]	[168,81,NaN]	-2	hSpCas9	negative selection	9800892
41501488	41501511	15	-	27869803	PATU8988S	viability after 35 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	0.20913100216321784	[360]	[199,135,NaN]	2	hSpCas9	negative selection	9800893
41501641	41501664	15	+	27869803	PATU8988S	viability after 35 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.464533668219686	[226]	[167,336,NaN]	9	hSpCas9	negative selection	9800894
41502081	41502104	15	+	27869803	PATU8988S	viability after 35 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	0.0480572570444911	[617]	[182,331,NaN]	0	hSpCas9	negative selection	9800895
41502434	41502457	15	+	27869803	PATU8988S	viability after 35 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.15765729244354332	[358]	[181,76,NaN]	-2	hSpCas9	negative selection	9800896
41502802	41502825	15	-	27869803	PATU8988S	viability after 35 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-2.648411095950113	[139]	[5,11,NaN]	-9	hSpCas9	negative selection	9800897
41494155	41494178	15	-	27869803	PATU8988S	viability after 31 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	0.3372298135230908	[363]	[196,165,NaN]	4	hSpCas9	negative selection	9883341
41501488	41501511	15	-	27869803	PATU8988S	viability after 31 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	0.1686031282558007	[360]	[119,214,NaN]	2	hSpCas9	negative selection	9883342
41501641	41501664	15	+	27869803	PATU8988S	viability after 31 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	1.2277311361816448	[226]	[134,309,NaN]	9	hSpCas9	negative selection	9883343
41502081	41502104	15	+	27869803	PATU8988S	viability after 31 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	0.1268191636794835	[617]	[199,356,NaN]	1	hSpCas9	negative selection	9883344
41502434	41502457	15	+	27869803	PATU8988S	viability after 31 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.24342913931131271	[358]	[134,102,NaN]	-3	hSpCas9	negative selection	9883345
41502802	41502825	15	-	27869803	PATU8988S	viability after 31 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-1.8693459579307259	[139]	[9,21,NaN]	-9	hSpCas9	negative selection	9883346
41494155	41494178	15	-	27869803	HPAFII	viability after 35 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	1.323165192550746	[203]	[486,0,NaN]	8	hSpCas9	negative selection	9965790
41501488	41501511	15	-	27869803	HPAFII	viability after 35 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-2.0076623878729443	[106]	[12,13,NaN]	-7	hSpCas9	negative selection	9965791
41501641	41501664	15	+	27869803	HPAFII	viability after 35 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.2679974250830558	[145]	[88,88,NaN]	1	hSpCas9	negative selection	9965792
41502081	41502104	15	+	27869803	HPAFII	viability after 35 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-1.6266531372652913	[286]	[31,63,NaN]	-7	hSpCas9	negative selection	9965793
41502434	41502457	15	+	27869803	HPAFII	viability after 35 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	0.09438527878596459	[172]	[156,21,NaN]	0	hSpCas9	negative selection	9965794
41502802	41502825	15	-	27869803	HPAFII	viability after 35 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-1.0910930041507978	[73]	[10,24,NaN]	-6	hSpCas9	negative selection	9965795
41494155	41494178	15	-	27869803	HPAFII	viability after 31 days	CGGTCAGCTGAGGGATCACCGGG	ITPKA	ENSG00000137825	1.1763210835906779	[203]	[453,45,NaN]	8	hSpCas9	negative selection	10048239
41501488	41501511	15	-	27869803	HPAFII	viability after 31 days	TATGACCGGCAGATTGACCATGG	ITPKA	ENSG00000137825	-0.9749953117945223	[106]	[53,4,NaN]	-6	hSpCas9	negative selection	10048240
41501641	41501664	15	+	27869803	HPAFII	viability after 31 days	TTAAGGCGGCGGGCACCAGCGGG	ITPKA	ENSG00000137825	0.7985816801598937	[145]	[142,141,NaN]	6	hSpCas9	negative selection	10048241
41502081	41502104	15	+	27869803	HPAFII	viability after 31 days	TCCTGAAGCTCCCACGGAGGAGG	ITPKA	ENSG00000137825	-1.6420368716699927	[286]	[53,48,NaN]	-7	hSpCas9	negative selection	10048242
41502434	41502457	15	+	27869803	HPAFII	viability after 31 days	GACTACGCGAAGCCGAGAGCAGG	ITPKA	ENSG00000137825	-0.11951524759908094	[172]	[119,55,NaN]	-1	hSpCas9	negative selection	10048243
41502802	41502825	15	-	27869803	HPAFII	viability after 31 days	TGTCCCGGATCTGCTGCAGGCGG	ITPKA	ENSG00000137825	-2.4165769441817515	[73]	[13,0,NaN]	-8	hSpCas9	negative selection	10048244
41502811	41502834	15	+	28162770	P31FUJ	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.3940831114474394	[207]	[185]	-4	hSpCas9	negative selection	10176492
41502057	41502080	15	+	28162770	P31FUJ	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	0.05866060974593257	[66]	[81]	0	hSpCas9	negative selection	10176493
41494154	41494177	15	-	28162770	P31FUJ	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-1.3703057281643138	[54]	[24]	-7	hSpCas9	negative selection	10176494
41494233	41494256	15	+	28162770	P31FUJ	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	1.0302322014194152	[24]	[59]	9	hSpCas9	negative selection	10176495
41494289	41494312	15	-	28162770	P31FUJ	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	-2.283428277484347	[28]	[6]	-8	hSpCas9	negative selection	10176496
41494307	41494330	15	-	28162770	P31FUJ	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-1.1915795416878656	[137]	[70]	-7	hSpCas9	negative selection	10176497
41494320	41494343	15	+	28162770	P31FUJ	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	0.7671977955856215	[44]	[89]	8	hSpCas9	negative selection	10176498
41494357	41494380	15	+	28162770	P31FUJ	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.6033729936797269	[176]	[315]	7	hSpCas9	negative selection	10176499
41501991	41502014	15	+	28162770	P31FUJ	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	-0.21192347473846257	[342]	[347]	-2	hSpCas9	negative selection	10176500
41502030	41502053	15	+	28162770	P31FUJ	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.3455575614825307	[218]	[326]	4	hSpCas9	negative selection	10176501
41502811	41502834	15	+	28162770	TF1	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10345858
41502057	41502080	15	+	28162770	TF1	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10345859
41494154	41494177	15	-	28162770	TF1	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10345860
41494233	41494256	15	+	28162770	TF1	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10345861
41494289	41494312	15	-	28162770	TF1	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10345862
41494307	41494330	15	-	28162770	TF1	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10345863
41494320	41494343	15	+	28162770	TF1	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10345864
41494357	41494380	15	+	28162770	TF1	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	NaN	[NaN]	[191]	1	hSpCas9	negative selection	10345865
41501991	41502014	15	+	28162770	TF1	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10345866
41502030	41502053	15	+	28162770	TF1	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	NaN	[NaN]	[338]	1	hSpCas9	negative selection	10345867
41502811	41502834	15	+	28162770	SKM1	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.5344251079254201	[67]	[82]	-4	hSpCas9	negative selection	10515224
41502057	41502080	15	+	28162770	SKM1	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.8220016980220053	[20]	[20]	-6	hSpCas9	negative selection	10515225
41494154	41494177	15	-	28162770	SKM1	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.5224414161630975	[12]	[15]	-4	hSpCas9	negative selection	10515226
41494233	41494256	15	+	28162770	SKM1	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	-0.3365748708517635	[14]	[20]	-3	hSpCas9	negative selection	10515227
41494289	41494312	15	-	28162770	SKM1	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	0.0524674198941355	[5]	[10]	0	hSpCas9	negative selection	10515228
41494307	41494330	15	-	28162770	SKM1	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.4726674457939913	[72]	[92]	-4	hSpCas9	negative selection	10515229
41494320	41494343	15	+	28162770	SKM1	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-2.406964198743162	[8]	[2]	-8	hSpCas9	negative selection	10515230
41494357	41494380	15	+	28162770	SKM1	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.737425710592013	[37]	[111]	7	hSpCas9	negative selection	10515231
41501991	41502014	15	+	28162770	SKM1	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.33327652745590536	[65]	[146]	3	hSpCas9	negative selection	10515232
41502030	41502053	15	+	28162770	SKM1	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.20224584822467176	[58]	[119]	2	hSpCas9	negative selection	10515233
41502811	41502834	15	+	28162770	SKM1	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.5344251079254201	[67]	[82]	-4	hSpCas9	negative selection	10684590
41502057	41502080	15	+	28162770	SKM1	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.8220016980220053	[20]	[20]	-6	hSpCas9	negative selection	10684591
41494154	41494177	15	-	28162770	SKM1	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.5224414161630975	[12]	[15]	-4	hSpCas9	negative selection	10684592
41494233	41494256	15	+	28162770	SKM1	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	-0.3365748708517635	[14]	[20]	-3	hSpCas9	negative selection	10684593
41494289	41494312	15	-	28162770	SKM1	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	0.0524674198941355	[5]	[10]	0	hSpCas9	negative selection	10684594
41494307	41494330	15	-	28162770	SKM1	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.4726674457939913	[72]	[92]	-4	hSpCas9	negative selection	10684595
41494320	41494343	15	+	28162770	SKM1	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-2.406964198743162	[8]	[2]	-8	hSpCas9	negative selection	10684596
41494357	41494380	15	+	28162770	SKM1	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.737425710592013	[37]	[111]	7	hSpCas9	negative selection	10684597
41501991	41502014	15	+	28162770	SKM1	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.33327652745590536	[65]	[146]	3	hSpCas9	negative selection	10684598
41502030	41502053	15	+	28162770	SKM1	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.20224584822467176	[58]	[119]	2	hSpCas9	negative selection	10684599
41502811	41502834	15	+	28162770	PL21	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	0.05718166064727703	[317]	[143]	0	hSpCas9	negative selection	10853956
41502057	41502080	15	+	28162770	PL21	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-2.323422341567693	[45]	[3]	-8	hSpCas9	negative selection	10853957
41494154	41494177	15	-	28162770	PL21	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.9323106815343294	[56]	[12]	-6	hSpCas9	negative selection	10853958
41494233	41494256	15	+	28162770	PL21	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	0.9463830222435372	[30]	[25]	7	hSpCas9	negative selection	10853959
41494289	41494312	15	-	28162770	PL21	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	1.1543359248761953	[31]	[30]	8	hSpCas9	negative selection	10853960
41494307	41494330	15	-	28162770	PL21	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.7732252590072132	[160]	[40]	-5	hSpCas9	negative selection	10853961
41494320	41494343	15	+	28162770	PL21	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	0.12975028659792187	[41]	[19]	1	hSpCas9	negative selection	10853962
41494357	41494380	15	+	28162770	PL21	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	-0.07486743301054966	[120]	[49]	0	hSpCas9	negative selection	10853963
41501991	41502014	15	+	28162770	PL21	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.6750485697455626	[235]	[163]	6	hSpCas9	negative selection	10853964
41502030	41502053	15	+	28162770	PL21	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.2966475953426664	[158]	[84]	2	hSpCas9	negative selection	10853965
41502811	41502834	15	+	28162770	P31FUJ	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.3940831114474394	[207]	[185]	-4	hSpCas9	negative selection	11023322
41502057	41502080	15	+	28162770	P31FUJ	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	0.05866060974593257	[66]	[81]	0	hSpCas9	negative selection	11023323
41494154	41494177	15	-	28162770	P31FUJ	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-1.3703057281643138	[54]	[24]	-7	hSpCas9	negative selection	11023324
41494233	41494256	15	+	28162770	P31FUJ	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	1.0302322014194152	[24]	[59]	9	hSpCas9	negative selection	11023325
41494289	41494312	15	-	28162770	P31FUJ	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	-2.283428277484347	[28]	[6]	-8	hSpCas9	negative selection	11023326
41494307	41494330	15	-	28162770	P31FUJ	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-1.1915795416878656	[137]	[70]	-7	hSpCas9	negative selection	11023327
41494320	41494343	15	+	28162770	P31FUJ	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	0.7671977955856215	[44]	[89]	8	hSpCas9	negative selection	11023328
41494357	41494380	15	+	28162770	P31FUJ	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.6033729936797269	[176]	[315]	7	hSpCas9	negative selection	11023329
41501991	41502014	15	+	28162770	P31FUJ	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	-0.21192347473846257	[342]	[347]	-2	hSpCas9	negative selection	11023330
41502030	41502053	15	+	28162770	P31FUJ	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.3455575614825307	[218]	[326]	4	hSpCas9	negative selection	11023331
41502811	41502834	15	+	28162770	OCIAML5	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	0.6760335929014829	[68]	[198]	6	hSpCas9	negative selection	11192688
41502057	41502080	15	+	28162770	OCIAML5	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.14805139849907756	[61]	[100]	-1	hSpCas9	negative selection	11192689
41494154	41494177	15	-	28162770	OCIAML5	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-3.3374933980342387	[27]	[4]	-9	hSpCas9	negative selection	11192690
41494233	41494256	15	+	28162770	OCIAML5	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	0.8483731472770952	[19]	[64]	7	hSpCas9	negative selection	11192691
41494289	41494312	15	-	28162770	OCIAML5	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	-3.6594214929216013	[13]	[1]	-9	hSpCas9	negative selection	11192692
41494307	41494330	15	-	28162770	OCIAML5	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.49252418417685684	[105]	[135]	-3	hSpCas9	negative selection	11192693
41494320	41494343	15	+	28162770	OCIAML5	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-1.5525062890050894	[25]	[15]	-7	hSpCas9	negative selection	11192694
41494357	41494380	15	+	28162770	OCIAML5	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	-0.033904893849810075	[113]	[200]	0	hSpCas9	negative selection	11192695
41501991	41502014	15	+	28162770	OCIAML5	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	-0.22657626356023053	[233]	[360]	-2	hSpCas9	negative selection	11192696
41502030	41502053	15	+	28162770	OCIAML5	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	-0.2581709453728329	[160]	[242]	-2	hSpCas9	negative selection	11192697
41502811	41502834	15	+	28162770	EOL1	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.16325860939827264	[524]	[246]	-1	hSpCas9	negative selection	11362054
41502057	41502080	15	+	28162770	EOL1	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	0.29227955607102163	[61]	[39]	2	hSpCas9	negative selection	11362055
41494154	41494177	15	-	28162770	EOL1	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	0.2893120643681548	[72]	[46]	2	hSpCas9	negative selection	11362056
41494233	41494256	15	+	28162770	EOL1	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	-1.6943620610739594	[85]	[13]	-8	hSpCas9	negative selection	11362057
41494289	41494312	15	-	28162770	EOL1	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	0.3861278567864086	[60]	[41]	3	hSpCas9	negative selection	11362058
41494307	41494330	15	-	28162770	EOL1	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.7840890995371772	[352]	[107]	-5	hSpCas9	negative selection	11362059
41494320	41494343	15	+	28162770	EOL1	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	2.0860111942646506	[37]	[84]	9	hSpCas9	negative selection	11362060
41494357	41494380	15	+	28162770	EOL1	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.038204553366101734	[243]	[131]	0	hSpCas9	negative selection	11362061
41501991	41502014	15	+	28162770	EOL1	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	1.424976762080023	[286]	[405]	9	hSpCas9	negative selection	11362062
41502030	41502053	15	+	28162770	EOL1	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.7667854088367996	[250]	[224]	6	hSpCas9	negative selection	11362063
41502811	41502834	15	+	28162770	MOLM13	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.37506690830984113	[399]	[222]	-2	hSpCas9	negative selection	11531420
41502057	41502080	15	+	28162770	MOLM13	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.4210793060666773	[99]	[53]	-3	hSpCas9	negative selection	11531421
41494154	41494177	15	-	28162770	MOLM13	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	0.7508233448160775	[59]	[72]	5	hSpCas9	negative selection	11531422
41494233	41494256	15	+	28162770	MOLM13	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	-1.6789520067846921	[61]	[13]	-7	hSpCas9	negative selection	11531423
41494289	41494312	15	-	28162770	MOLM13	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	-2.854038713342784	[39]	[3]	-8	hSpCas9	negative selection	11531424
41494307	41494330	15	-	28162770	MOLM13	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	0.1853588000849877	[297]	[244]	1	hSpCas9	negative selection	11531425
41494320	41494343	15	+	28162770	MOLM13	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-0.6925752906486671	[37]	[16]	-4	hSpCas9	negative selection	11531426
41494357	41494380	15	+	28162770	MOLM13	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	-1.6514095468277656	[251]	[57]	-7	hSpCas9	negative selection	11531427
41501991	41502014	15	+	28162770	MOLM13	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.02605182292201963	[325]	[239]	0	hSpCas9	negative selection	11531428
41502030	41502053	15	+	28162770	MOLM13	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	1.082599225659787	[191]	[293]	8	hSpCas9	negative selection	11531429
41502811	41502834	15	+	28162770	HEL	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.17722613891248973	[315]	[178]	-1	hSpCas9	negative selection	11700786
41502057	41502080	15	+	28162770	HEL	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.4765600963719874	[62]	[28]	-3	hSpCas9	negative selection	11700787
41494154	41494177	15	-	28162770	HEL	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-1.7030360048413733	[60]	[11]	-7	hSpCas9	negative selection	11700788
41494233	41494256	15	+	28162770	HEL	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	-0.2170835099513826	[48]	[26]	-1	hSpCas9	negative selection	11700789
41494289	41494312	15	-	28162770	HEL	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	-0.8906933680807172	[54]	[18]	-5	hSpCas9	negative selection	11700790
41494307	41494330	15	-	28162770	HEL	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-1.1325548808249488	[266]	[77]	-6	hSpCas9	negative selection	11700791
41494320	41494343	15	+	28162770	HEL	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-3.057700886140735	[25]	[1]	-8	hSpCas9	negative selection	11700792
41494357	41494380	15	+	28162770	HEL	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.04950871529560025	[174]	[115]	0	hSpCas9	negative selection	11700793
41501991	41502014	15	+	28162770	HEL	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	-0.39522901819866346	[307]	[149]	-3	hSpCas9	negative selection	11700794
41502030	41502053	15	+	28162770	HEL	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	-0.9359646782491171	[229]	[76]	-5	hSpCas9	negative selection	11700795
41502811	41502834	15	+	28162770	MV411	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.6170474785607436	[263]	[144]	-4	hSpCas9	negative selection	11870152
41502057	41502080	15	+	28162770	MV411	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.2023653666567451	[55]	[40]	-1	hSpCas9	negative selection	11870153
41494154	41494177	15	-	28162770	MV411	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-3.00048996266081	[56]	[5]	-9	hSpCas9	negative selection	11870154
41494233	41494256	15	+	28162770	MV411	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	1.214270686847576	[21]	[42]	9	hSpCas9	negative selection	11870155
41494289	41494312	15	-	28162770	MV411	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	0.4318621219202028	[43]	[49]	4	hSpCas9	negative selection	11870156
41494307	41494330	15	-	28162770	MV411	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.45105389556879505	[184]	[113]	-3	hSpCas9	negative selection	11870157
41494320	41494343	15	+	28162770	MV411	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	0.24743755078277463	[6]	[6]	2	hSpCas9	negative selection	11870158
41494357	41494380	15	+	28162770	MV411	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	-0.2642759679077423	[143]	[100]	-2	hSpCas9	negative selection	11870159
41501991	41502014	15	+	28162770	MV411	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	-0.6192959183537604	[247]	[135]	-4	hSpCas9	negative selection	11870160
41502030	41502053	15	+	28162770	MV411	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.36462109015311434	[129]	[140]	3	hSpCas9	negative selection	11870161
41502811	41502834	15	+	28162770	MONOMAC1	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	0.31953867868135255	[143]	[205]	3	hSpCas9	negative selection	12039518
41502057	41502080	15	+	28162770	MONOMAC1	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-0.38259250021563007	[57]	[50]	-3	hSpCas9	negative selection	12039519
41494154	41494177	15	-	28162770	MONOMAC1	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	2.062349781759096	[32]	[157]	9	hSpCas9	negative selection	12039520
41494233	41494256	15	+	28162770	MONOMAC1	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	0.025355574276894277	[17]	[20]	0	hSpCas9	negative selection	12039521
41494289	41494312	15	-	28162770	MONOMAC1	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	-1.3039520509760658	[27]	[12]	-7	hSpCas9	negative selection	12039522
41494307	41494330	15	-	28162770	MONOMAC1	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-0.4117756958525663	[93]	[80]	-4	hSpCas9	negative selection	12039523
41494320	41494343	15	+	28162770	MONOMAC1	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-0.7376052284222565	[15]	[10]	-6	hSpCas9	negative selection	12039524
41494357	41494380	15	+	28162770	MONOMAC1	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.020868183284580455	[91]	[106]	0	hSpCas9	negative selection	12039525
41501991	41502014	15	+	28162770	MONOMAC1	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.2204689078100399	[145]	[194]	2	hSpCas9	negative selection	12039526
41502030	41502053	15	+	28162770	MONOMAC1	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	-0.6614404236593772	[108]	[78]	-5	hSpCas9	negative selection	12039527
41502811	41502834	15	+	28162770	OCIAML2	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.4045406347843887	[47]	[200]	-3	hSpCas9	negative selection	12208884
41502057	41502080	15	+	28162770	OCIAML2	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	0.2383213927544483	[12]	[84]	2	hSpCas9	negative selection	12208885
41494154	41494177	15	-	28162770	OCIAML2	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.07208044875188624	[10]	[57]	0	hSpCas9	negative selection	12208886
41494233	41494256	15	+	28162770	OCIAML2	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	-1.608133348992096	[10]	[19]	-7	hSpCas9	negative selection	12208887
41494289	41494312	15	-	28162770	OCIAML2	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	-0.30070482379984886	[3]	[17]	-2	hSpCas9	negative selection	12208888
41494307	41494330	15	-	28162770	OCIAML2	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	0.2921939368450708	[46]	[318]	3	hSpCas9	negative selection	12208889
41494320	41494343	15	+	28162770	OCIAML2	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-0.968129484712978	[5]	[16]	-6	hSpCas9	negative selection	12208890
41494357	41494380	15	+	28162770	OCIAML2	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	-0.11307782062407751	[31]	[163]	-1	hSpCas9	negative selection	12208891
41501991	41502014	15	+	28162770	OCIAML2	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	0.17322636453256357	[47]	[299]	1	hSpCas9	negative selection	12208892
41502030	41502053	15	+	28162770	OCIAML2	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	0.8564415729211606	[27]	[280]	8	hSpCas9	negative selection	12208893
41502811	41502834	15	+	28162770	OCIAML3	viability	GCAGATCCGGGACACCCTGGAGG	ITPKA	ENSG00000137825	-0.5173863587212507	[54]	[115]	-4	hSpCas9	negative selection	12378250
41502057	41502080	15	+	28162770	OCIAML3	viability	GTACAAGAAAATGCTGGCGGTGG	ITPKA	ENSG00000137825	-1.206984517214916	[12]	[16]	-7	hSpCas9	negative selection	12378251
41494154	41494177	15	-	28162770	OCIAML3	viability	GGTCAGCTGAGGGATCACCGGGG	ITPKA	ENSG00000137825	-0.5008982359326815	[14]	[31]	-4	hSpCas9	negative selection	12378252
41494233	41494256	15	+	28162770	OCIAML3	viability	GAGGGACTGCCTCCCGGCAGCGG	ITPKA	ENSG00000137825	0.29907715575932503	[6]	[25]	3	hSpCas9	negative selection	12378253
41494289	41494312	15	-	28162770	OCIAML3	viability	AGTGGAGGAGACCGACGAGGTGG	ITPKA	ENSG00000137825	2.3832722831757533	[3]	[62]	9	hSpCas9	negative selection	12378254
41494307	41494330	15	-	28162770	OCIAML3	viability	GAGCAGCGACGAGGAGCCAGTGG	ITPKA	ENSG00000137825	-1.0899651349865747	[54]	[77]	-7	hSpCas9	negative selection	12378255
41494320	41494343	15	+	28162770	OCIAML3	viability	GTCGCTGCTCGAGGACTCGGAGG	ITPKA	ENSG00000137825	-0.20169021754540273	[7]	[20]	-1	hSpCas9	negative selection	12378256
41494357	41494380	15	+	28162770	OCIAML3	viability	GACAGTGAGAGCCGGAGCCGCGG	ITPKA	ENSG00000137825	0.27224097078700943	[47]	[174]	2	hSpCas9	negative selection	12378257
41501991	41502014	15	+	28162770	OCIAML3	viability	CCACAGGACTTACCTAGAGGAGG	ITPKA	ENSG00000137825	-0.3174900051267473	[70]	[171]	-2	hSpCas9	negative selection	12378258
41502030	41502053	15	+	28162770	OCIAML3	viability	TGAGCGGCCCAAGCTGCGGAAGG	ITPKA	ENSG00000137825	-0.11453826845032088	[51]	[144]	-1	hSpCas9	negative selection	12378259