Crispr
Gene Info
- Species: Human
(Homo sapiens)
- GeneID: 440400
- Symbol: RNASEK
- Description: ribonuclease K
DataSource:
http://genomecrispr.dkfz.de/#!/results/RNASEK
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| Start |
The end |
chr |
strand |
pubmed |
cellline |
condition |
sequence |
symbol |
ensg |
log2fc |
rc_initial |
rc_final |
effect |
cas |
screentype |
index |
7012565 |
7012588 |
17 |
+ |
26472758 |
Jiyoye |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.38020833390560405 |
[107] |
[105] |
3 |
hSpCas9 |
negative selection |
137713 |
7012606 |
7012629 |
17 |
- |
26472758 |
Jiyoye |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.17271012786885054 |
[19] |
[16] |
1 |
hSpCas9 |
negative selection |
137714 |
7012565 |
7012588 |
17 |
+ |
26472758 |
KBM7 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.5435089749101661 |
[540,393] |
[216,405] |
6 |
hSpCas9 |
negative selection |
328831 |
7012606 |
7012629 |
17 |
- |
26472758 |
KBM7 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
-0.13651515127321456 |
[218,129] |
[71,73] |
-1 |
hSpCas9 |
negative selection |
328832 |
7012565 |
7012588 |
17 |
+ |
26472758 |
Raji |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.9112410131949766 |
[235] |
[102] |
8 |
hSpCas9 |
negative selection |
519949 |
7012606 |
7012629 |
17 |
- |
26472758 |
Raji |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.04848984632003073 |
[74] |
[17] |
0 |
hSpCas9 |
negative selection |
519950 |
7012565 |
7012588 |
17 |
+ |
26472758 |
K562 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
1.4877296130396622 |
[312] |
[740] |
9 |
hSpCas9 |
negative selection |
711067 |
7012606 |
7012629 |
17 |
- |
26472758 |
K562 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.9944404746580993 |
[87] |
[147] |
8 |
hSpCas9 |
negative selection |
711068 |
7012605 |
7012628 |
17 |
- |
26627737 |
DLD1 |
viability |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.9958539414716381 |
[695] |
[151,79,95] |
-7 |
hSpCas9 |
negative selection |
799598 |
7012605 |
7012628 |
17 |
- |
26627737 |
GBM cells |
viability after 5 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.7286099646976918 |
[237] |
[214,207] |
8 |
hSpCas9 |
negative selection |
881913 |
7012605 |
7012628 |
17 |
- |
26627737 |
GBM cells |
viability after 13 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.8043160251171274 |
[237] |
[203,242] |
8 |
hSpCas9 |
negative selection |
964228 |
7012605 |
7012628 |
17 |
- |
26627737 |
GBM cells |
viability after 21 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
1.0009854590762686 |
[237] |
[263,253] |
8 |
hSpCas9 |
negative selection |
1046543 |
7012605 |
7012628 |
17 |
- |
26627737 |
RPE1 |
viability after 9 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.3029503517305371 |
[1348] |
[385,285] |
-2 |
hSpCas9 |
negative selection |
1128858 |
7012605 |
7012628 |
17 |
- |
26627737 |
RPE1 |
viability after 12 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.4809403801950482 |
[1348] |
[350,162] |
-3 |
hSpCas9 |
negative selection |
1211173 |
7012605 |
7012628 |
17 |
- |
26627737 |
RPE1 |
viability after 15 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.9057902445027993 |
[1348] |
[249,158] |
-5 |
hSpCas9 |
negative selection |
1293488 |
7012605 |
7012628 |
17 |
- |
26627737 |
RPE1 |
viability after 18 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-1.4446751940700837 |
[1348] |
[169,94] |
-7 |
hSpCas9 |
negative selection |
1375803 |
7012605 |
7012628 |
17 |
- |
26627737 |
HeLa |
viability after 8 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.2560572784210733 |
[343] |
[294,30,231] |
2 |
hSpCas9 |
negative selection |
1458118 |
7012605 |
7012628 |
17 |
- |
26627737 |
HeLa |
viability after 12 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.15238098954169357 |
[343] |
[17,217,134] |
-1 |
hSpCas9 |
negative selection |
1540433 |
7012605 |
7012628 |
17 |
- |
26627737 |
HeLa |
viability after 15 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.09605272370408613 |
[343] |
[106,163,180] |
0 |
hSpCas9 |
negative selection |
1622748 |
7012605 |
7012628 |
17 |
- |
26627737 |
HeLa |
viability after 18 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.11656607684607073 |
[343] |
[74,136,180] |
1 |
hSpCas9 |
negative selection |
1705063 |
7012605 |
7012628 |
17 |
- |
26627737 |
HCT116 |
viability after 6 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
1.5456538554350647 |
[651] |
[373,257] |
7 |
hSpCas9 |
negative selection |
1787378 |
7012605 |
7012628 |
17 |
- |
26627737 |
HCT116 |
viability after 8 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.4285513517464742 |
[420] |
[91,196,225] |
-5 |
hSpCas9 |
negative selection |
1869693 |
7012605 |
7012628 |
17 |
- |
26627737 |
HCT116 |
viability after 9 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.5570230139614705 |
[651] |
[416,128] |
4 |
hSpCas9 |
negative selection |
1952008 |
7012605 |
7012628 |
17 |
- |
26627737 |
HCT116 |
viability after 12 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.5624760963007904 |
[420] |
[101,81,267] |
-6 |
hSpCas9 |
negative selection |
2034323 |
7012605 |
7012628 |
17 |
- |
26627737 |
HCT116 |
viability after 15 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-1.032427321369499 |
[420] |
[160,95,102] |
-8 |
hSpCas9 |
negative selection |
2116638 |
7012605 |
7012628 |
17 |
- |
26627737 |
HCT116 |
viability after 18 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.755797397726981 |
[420] |
[150,78,134] |
-6 |
hSpCas9 |
negative selection |
2198953 |
7012431 |
7012454 |
17 |
- |
27661255 |
K562 |
viability |
GCGTGAGTATTGGAAGAGCGAGG |
RNASEK |
ENSG00000219200 |
-0.851816277586617 |
[397,381] |
[182,163] |
-8 |
dCas9-KRAB |
negative selection |
5507715 |
7012605 |
7012628 |
17 |
- |
27869803 |
HPAFII |
viability after 27 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.41637394684165785 |
[239] |
[75,109,NaN] |
-3 |
hSpCas9 |
negative selection |
9562628 |
7012605 |
7012628 |
17 |
- |
27869803 |
HPAFII |
viability after 15 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.22878003167657762 |
[239] |
[403,238,NaN] |
2 |
hSpCas9 |
negative selection |
9645077 |
7012605 |
7012628 |
17 |
- |
27869803 |
ASPC1 |
viability after 36 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.24285541889739906 |
[607] |
[111,113,454] |
2 |
hSpCas9 |
negative selection |
9727526 |
7012605 |
7012628 |
17 |
- |
27869803 |
PATU8988S |
viability after 35 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
1.1041446058448008 |
[586] |
[605,409,NaN] |
9 |
hSpCas9 |
negative selection |
9809975 |
7012605 |
7012628 |
17 |
- |
27869803 |
PATU8988S |
viability after 31 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
0.9181888813262024 |
[586] |
[429,457,NaN] |
8 |
hSpCas9 |
negative selection |
9892424 |
7012605 |
7012628 |
17 |
- |
27869803 |
HPAFII |
viability after 35 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.33574678725680435 |
[239] |
[52,144,NaN] |
-2 |
hSpCas9 |
negative selection |
9974873 |
7012605 |
7012628 |
17 |
- |
27869803 |
HPAFII |
viability after 31 days |
AAGCCCAGGATGCCCTCGCAGGG |
RNASEK |
ENSG00000219200 |
-0.5776643690460899 |
[239] |
[106,71,NaN] |
-4 |
hSpCas9 |
negative selection |
10057322 |
7012565 |
7012588 |
17 |
+ |
28162770 |
P31FUJ |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.9681848533187984 |
[193] |
[445] |
9 |
hSpCas9 |
negative selection |
10225886 |
7012606 |
7012629 |
17 |
- |
28162770 |
P31FUJ |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.2266294142229186 |
[79] |
[109] |
2 |
hSpCas9 |
negative selection |
10225887 |
7012565 |
7012588 |
17 |
+ |
28162770 |
TF1 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
NaN |
[NaN] |
[309] |
1 |
hSpCas9 |
negative selection |
10395252 |
7012606 |
7012629 |
17 |
- |
28162770 |
TF1 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
NaN |
[NaN] |
[62] |
1 |
hSpCas9 |
negative selection |
10395253 |
7012565 |
7012588 |
17 |
+ |
28162770 |
SKM1 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
1.2083719510215134 |
[46] |
[191] |
9 |
hSpCas9 |
negative selection |
10564618 |
7012606 |
7012629 |
17 |
- |
28162770 |
SKM1 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.2654611432283338 |
[7] |
[16] |
2 |
hSpCas9 |
negative selection |
10564619 |
7012565 |
7012588 |
17 |
+ |
28162770 |
SKM1 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
1.2083719510215134 |
[46] |
[191] |
9 |
hSpCas9 |
negative selection |
10733984 |
7012606 |
7012629 |
17 |
- |
28162770 |
SKM1 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.2654611432283338 |
[7] |
[16] |
2 |
hSpCas9 |
negative selection |
10733985 |
7012565 |
7012588 |
17 |
+ |
28162770 |
PL21 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.28182341208302814 |
[205] |
[108] |
2 |
hSpCas9 |
negative selection |
10903350 |
7012606 |
7012629 |
17 |
- |
28162770 |
PL21 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
2.030214613047008 |
[35] |
[63] |
9 |
hSpCas9 |
negative selection |
10903351 |
7012565 |
7012588 |
17 |
+ |
28162770 |
P31FUJ |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.9681848533187984 |
[193] |
[445] |
9 |
hSpCas9 |
negative selection |
11072716 |
7012606 |
7012629 |
17 |
- |
28162770 |
P31FUJ |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.2266294142229186 |
[79] |
[109] |
2 |
hSpCas9 |
negative selection |
11072717 |
7012565 |
7012588 |
17 |
+ |
28162770 |
OCIAML5 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.8336409035969763 |
[105] |
[340] |
7 |
hSpCas9 |
negative selection |
11242082 |
7012606 |
7012629 |
17 |
- |
28162770 |
OCIAML5 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
-1.1546293408844281 |
[36] |
[29] |
-6 |
hSpCas9 |
negative selection |
11242083 |
7012565 |
7012588 |
17 |
+ |
28162770 |
EOL1 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
1.7338156597084922 |
[322] |
[565] |
9 |
hSpCas9 |
negative selection |
11411448 |
7012606 |
7012629 |
17 |
- |
28162770 |
EOL1 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
-1.738417241151895 |
[56] |
[8] |
-8 |
hSpCas9 |
negative selection |
11411449 |
7012565 |
7012588 |
17 |
+ |
28162770 |
MOLM13 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
1.6737653655830436 |
[250] |
[578] |
9 |
hSpCas9 |
negative selection |
11580814 |
7012606 |
7012629 |
17 |
- |
28162770 |
MOLM13 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.016510035202014883 |
[66] |
[48] |
0 |
hSpCas9 |
negative selection |
11580815 |
7012565 |
7012588 |
17 |
+ |
28162770 |
HEL |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.9038636478255194 |
[251] |
[301] |
7 |
hSpCas9 |
negative selection |
11750180 |
7012606 |
7012629 |
17 |
- |
28162770 |
HEL |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
-0.6791892628870055 |
[39] |
[15] |
-4 |
hSpCas9 |
negative selection |
11750181 |
7012565 |
7012588 |
17 |
+ |
28162770 |
MV411 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
-0.011095462816077761 |
[255] |
[213] |
0 |
hSpCas9 |
negative selection |
11919546 |
7012606 |
7012629 |
17 |
- |
28162770 |
MV411 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
0.2118136410520539 |
[40] |
[39] |
1 |
hSpCas9 |
negative selection |
11919547 |
7012565 |
7012588 |
17 |
+ |
28162770 |
MONOMAC1 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
-0.20643554506180334 |
[153] |
[152] |
-2 |
hSpCas9 |
negative selection |
12088912 |
7012606 |
7012629 |
17 |
- |
28162770 |
MONOMAC1 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
1.0480756507769775 |
[26] |
[63] |
8 |
hSpCas9 |
negative selection |
12088913 |
7012565 |
7012588 |
17 |
+ |
28162770 |
OCIAML2 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.7264070218173924 |
[40] |
[375] |
7 |
hSpCas9 |
negative selection |
12258278 |
7012606 |
7012629 |
17 |
- |
28162770 |
OCIAML2 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
-0.8856673245210049 |
[9] |
[29] |
-6 |
hSpCas9 |
negative selection |
12258279 |
7012565 |
7012588 |
17 |
+ |
28162770 |
OCIAML3 |
viability |
GGATGGGATGGTTGAGGCCGGGG |
RNASEK |
ENSG00000219200 |
0.058069056255530105 |
[62] |
[197] |
0 |
hSpCas9 |
negative selection |
12427644 |
7012606 |
7012629 |
17 |
- |
28162770 |
OCIAML3 |
viability |
AAAGCCCAGGATGCCCTCGCAGG |
RNASEK |
ENSG00000219200 |
-1.178970141045319 |
[11] |
[15] |
-7 |
hSpCas9 |
negative selection |
12427645 |