Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6323
  • Symbol: SCN1A
  • Description: sodium voltage-gated channel alpha subunit 1
DataSource: http://genomecrispr.dkfz.de/#!/results/SCN1A

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
166013837 166013860 2 - 26472758 Jiyoye viability AAGAAGGCAGAGGAAAACAATGG SCN1A ENSG00000144285 1.1076150996469654 [15] [25] 7 hSpCas9 negative selection 143019
166036412 166036435 2 - 26472758 Jiyoye viability GCTGTGGATAGGATGCACAAAGG SCN1A ENSG00000144285 -0.4955274171392116 [128] [68] -4 hSpCas9 negative selection 143020
166046823 166046846 2 - 26472758 Jiyoye viability GGAAGAAGCAGAACAGAAAGAGG SCN1A ENSG00000144285 0.8640330564793443 [101] [139] 6 hSpCas9 negative selection 143021
166045202 166045225 2 - 26472758 Jiyoye viability CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 -0.21323595521957256 [102] [66] -1 hSpCas9 negative selection 143022
166045170 166045193 2 - 26472758 Jiyoye viability AAACAGAAAGAGCAGTCTGGTGG SCN1A ENSG00000144285 0.20108477249852563 [307] [266] 1 hSpCas9 negative selection 143023
166045112 166045135 2 - 26472758 Jiyoye viability AATCTGAGGACAGCATCAGGAGG SCN1A ENSG00000144285 -0.3863737410267002 [103] [59] -3 hSpCas9 negative selection 143024
166045034 166045057 2 + 26472758 Jiyoye viability GTGCCATACCTGGTGTGGGGAGG SCN1A ENSG00000144285 -0.36753230665188386 [141] [82] -3 hSpCas9 negative selection 143025
166044011 166044034 2 - 26472758 Jiyoye viability GTGGCTCCCTATTTTCACCAAGG SCN1A ENSG00000144285 0.07540696399095803 [330] [262] 0 hSpCas9 negative selection 143026
166038019 166038042 2 + 26472758 Jiyoye viability GACGATGATGGCCAAGACGAGGG SCN1A ENSG00000144285 -0.2243297051523131 [188] [121] -2 hSpCas9 negative selection 143027
166037986 166038009 2 + 26472758 Jiyoye viability AAAGAGCTGCATGCCGACCACGG SCN1A ENSG00000144285 -0.46037432247047705 [103] [56] -3 hSpCas9 negative selection 143031
166013837 166013860 2 - 26472758 KBM7 viability AAGAAGGCAGAGGAAAACAATGG SCN1A ENSG00000144285 -0.11268111803376302 [57,100] [31,38] -1 hSpCas9 negative selection 334137
166036412 166036435 2 - 26472758 KBM7 viability GCTGTGGATAGGATGCACAAAGG SCN1A ENSG00000144285 0.5741437217944548 [400,540] [452,231] 6 hSpCas9 negative selection 334138
166046823 166046846 2 - 26472758 KBM7 viability GGAAGAAGCAGAACAGAAAGAGG SCN1A ENSG00000144285 0.3294973351861957 [345,297] [194,184] 3 hSpCas9 negative selection 334139
166045202 166045225 2 - 26472758 KBM7 viability CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 0.8989513851321758 [406,282] [441,169] 8 hSpCas9 negative selection 334140
166045170 166045193 2 - 26472758 KBM7 viability AAACAGAAAGAGCAGTCTGGTGG SCN1A ENSG00000144285 0.51014146641106 [910,849] [818,385] 5 hSpCas9 negative selection 334141
166045112 166045135 2 - 26472758 KBM7 viability AATCTGAGGACAGCATCAGGAGG SCN1A ENSG00000144285 0.6590689716061013 [494,285] [322,247] 7 hSpCas9 negative selection 334142
166045034 166045057 2 + 26472758 KBM7 viability GTGCCATACCTGGTGTGGGGAGG SCN1A ENSG00000144285 -0.06862023590400056 [508,492] [265,188] 0 hSpCas9 negative selection 334143
166044011 166044034 2 - 26472758 KBM7 viability GTGGCTCCCTATTTTCACCAAGG SCN1A ENSG00000144285 0.4822424624914914 [1186,1103] [606,883] 5 hSpCas9 negative selection 334144
166038019 166038042 2 + 26472758 KBM7 viability GACGATGATGGCCAAGACGAGGG SCN1A ENSG00000144285 0.3776280297229919 [1007,1065] [791,500] 4 hSpCas9 negative selection 334145
166037986 166038009 2 + 26472758 KBM7 viability AAAGAGCTGCATGCCGACCACGG SCN1A ENSG00000144285 -0.21345709363104193 [418,312] [147,145] -2 hSpCas9 negative selection 334149
166013837 166013860 2 - 26472758 Raji viability AAGAAGGCAGAGGAAAACAATGG SCN1A ENSG00000144285 -0.050157741612880447 [57] [12] 0 hSpCas9 negative selection 525255
166036412 166036435 2 - 26472758 Raji viability GCTGTGGATAGGATGCACAAAGG SCN1A ENSG00000144285 0.7288719121198697 [207] [79] 6 hSpCas9 negative selection 525256
166046823 166046846 2 - 26472758 Raji viability GGAAGAAGCAGAACAGAAAGAGG SCN1A ENSG00000144285 0.6199375405667057 [142] [50] 6 hSpCas9 negative selection 525257
166045202 166045225 2 - 26472758 Raji viability CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 -0.36770134757518336 [138] [24] -3 hSpCas9 negative selection 525258
166045170 166045193 2 - 26472758 Raji viability AAACAGAAAGAGCAGTCTGGTGG SCN1A ENSG00000144285 0.8359707117404839 [448] [185] 7 hSpCas9 negative selection 525259
166045112 166045135 2 - 26472758 Raji viability AATCTGAGGACAGCATCAGGAGG SCN1A ENSG00000144285 0.5224210346524433 [107] [35] 5 hSpCas9 negative selection 525260
166045034 166045057 2 + 26472758 Raji viability GTGCCATACCTGGTGTGGGGAGG SCN1A ENSG00000144285 1.122980390424618 [183] [92] 8 hSpCas9 negative selection 525261
166044011 166044034 2 - 26472758 Raji viability GTGGCTCCCTATTTTCACCAAGG SCN1A ENSG00000144285 0.7420523163118344 [522] [202] 7 hSpCas9 negative selection 525262
166038019 166038042 2 + 26472758 Raji viability GACGATGATGGCCAAGACGAGGG SCN1A ENSG00000144285 -0.09255403513515248 [339] [73] -1 hSpCas9 negative selection 525263
166037986 166038009 2 + 26472758 Raji viability AAAGAGCTGCATGCCGACCACGG SCN1A ENSG00000144285 -0.10021188403476783 [193] [41] -1 hSpCas9 negative selection 525267
166013837 166013860 2 - 26472758 K562 viability AAGAAGGCAGAGGAAAACAATGG SCN1A ENSG00000144285 -0.3405437730547094 [92] [61] -2 hSpCas9 negative selection 716373
166036412 166036435 2 - 26472758 K562 viability GCTGTGGATAGGATGCACAAAGG SCN1A ENSG00000144285 -0.35292749751054175 [350] [231] -2 hSpCas9 negative selection 716374
166046823 166046846 2 - 26472758 K562 viability GGAAGAAGCAGAACAGAAAGAGG SCN1A ENSG00000144285 0.6331158347665102 [303] [397] 5 hSpCas9 negative selection 716375
166045202 166045225 2 - 26472758 K562 viability CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 1.3763758789097387 [307] [674] 9 hSpCas9 negative selection 716376
166045170 166045193 2 - 26472758 K562 viability AAACAGAAAGAGCAGTCTGGTGG SCN1A ENSG00000144285 0.4169328505026082 [865] [975] 3 hSpCas9 negative selection 716377
166045112 166045135 2 - 26472758 K562 viability AATCTGAGGACAGCATCAGGAGG SCN1A ENSG00000144285 0.32533872305001454 [207] [219] 2 hSpCas9 negative selection 716378
166045034 166045057 2 + 26472758 K562 viability GTGCCATACCTGGTGTGGGGAGG SCN1A ENSG00000144285 1.2097817259944295 [273] [534] 8 hSpCas9 negative selection 716379
166044011 166044034 2 - 26472758 K562 viability GTGGCTCCCTATTTTCACCAAGG SCN1A ENSG00000144285 0.22017118141976977 [779] [766] 1 hSpCas9 negative selection 716380
166038019 166038042 2 + 26472758 K562 viability GACGATGATGGCCAAGACGAGGG SCN1A ENSG00000144285 0.28494653424905714 [701] [721] 2 hSpCas9 negative selection 716381
166037986 166038009 2 + 26472758 K562 viability AAAGAGCTGCATGCCGACCACGG SCN1A ENSG00000144285 -0.5107514618773499 [318] [188] -3 hSpCas9 negative selection 716385
165991303 165991326 2 + 26627737 DLD1 viability TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.7125188171689755 [350] [136,297,118] 7 hSpCas9 negative selection 809105
166036129 166036152 2 + 26627737 DLD1 viability TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.7453382956329951 [576] [224,390,295] 7 hSpCas9 negative selection 809106
166038018 166038041 2 + 26627737 DLD1 viability AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 0.3783078362533481 [1262] [425,728,409] 4 hSpCas9 negative selection 809107
166051938 166051961 2 + 26627737 DLD1 viability CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.475685355903945 [759] [255,468,279] 5 hSpCas9 negative selection 809108
166052833 166052856 2 + 26627737 DLD1 viability TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 0.36582690528510264 [118] [50,5,79] 4 hSpCas9 negative selection 809109
166073593 166073616 2 - 26627737 DLD1 viability CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.5305739851785012 [441] [244,287,86] 5 hSpCas9 negative selection 809110
165991303 165991326 2 + 26627737 GBM cells viability after 5 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.4760356223896585 [245] [170,195] 7 hSpCas9 negative selection 891420
166036129 166036152 2 + 26627737 GBM cells viability after 5 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.5911095989318693 [431] [393,303] 8 hSpCas9 negative selection 891421
166038018 166038041 2 + 26627737 GBM cells viability after 5 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.35900328956263894 [787] [257,400] -5 hSpCas9 negative selection 891422
166051938 166051961 2 + 26627737 GBM cells viability after 5 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.3502932212282499 [489] [336,332] 5 hSpCas9 negative selection 891423
166052833 166052856 2 + 26627737 GBM cells viability after 5 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 -0.37238814693170896 [69] [31,25] -5 hSpCas9 negative selection 891424
166073593 166073616 2 - 26627737 GBM cells viability after 5 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.703518185927255 [299] [257,265] 8 hSpCas9 negative selection 891425
165991303 165991326 2 + 26627737 GBM cells viability after 13 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.45250333009671195 [245] [164,196] 6 hSpCas9 negative selection 973735
166036129 166036152 2 + 26627737 GBM cells viability after 13 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.8969076425304332 [431] [527,361] 9 hSpCas9 negative selection 973736
166038018 166038041 2 + 26627737 GBM cells viability after 13 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.6165880183474222 [787] [333,233] -6 hSpCas9 negative selection 973737
166051938 166051961 2 + 26627737 GBM cells viability after 13 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.6189301569453838 [489] [447,375] 7 hSpCas9 negative selection 973738
166052833 166052856 2 + 26627737 GBM cells viability after 13 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 -0.4978033748681421 [69] [27,25] -5 hSpCas9 negative selection 973739
166073593 166073616 2 - 26627737 GBM cells viability after 13 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.4884059945458909 [299] [245,213] 6 hSpCas9 negative selection 973740
165991303 165991326 2 + 26627737 GBM cells viability after 21 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.602896772325098 [245] [226,180] 6 hSpCas9 negative selection 1056050
166036129 166036152 2 + 26627737 GBM cells viability after 21 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.7456470943308797 [431] [392,393] 7 hSpCas9 negative selection 1056051
166038018 166038041 2 + 26627737 GBM cells viability after 21 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.49959712474234874 [787] [330,276] -4 hSpCas9 negative selection 1056052
166051938 166051961 2 + 26627737 GBM cells viability after 21 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.7811882552280811 [489] [445,467] 7 hSpCas9 negative selection 1056053
166052833 166052856 2 + 26627737 GBM cells viability after 21 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 0.7743042167497676 [69] [63,65] 7 hSpCas9 negative selection 1056054
166073593 166073616 2 - 26627737 GBM cells viability after 21 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.3386930791856309 [299] [226,186] 3 hSpCas9 negative selection 1056055
165991303 165991326 2 + 26627737 RPE1 viability after 9 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.4876697522856564 [602] [210,333] 3 hSpCas9 negative selection 1138365
166036129 166036152 2 + 26627737 RPE1 viability after 9 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.7556219639869546 [1079] [407,780] 5 hSpCas9 negative selection 1138366
166038018 166038041 2 + 26627737 RPE1 viability after 9 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 0.1592708833542742 [2792] [679,1358] 1 hSpCas9 negative selection 1138367
166051938 166051961 2 + 26627737 RPE1 viability after 9 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.9391655907921304 [1987] [1095,1318] 6 hSpCas9 negative selection 1138368
166052833 166052856 2 + 26627737 RPE1 viability after 9 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 -1.0481359903447167 [334] [34,70] -6 hSpCas9 negative selection 1138369
166073593 166073616 2 - 26627737 RPE1 viability after 9 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.0659181219116769 [950] [322,296] 0 hSpCas9 negative selection 1138370
165991303 165991326 2 + 26627737 RPE1 viability after 12 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.4960573753849781 [602] [193,264] 3 hSpCas9 negative selection 1220680
166036129 166036152 2 + 26627737 RPE1 viability after 12 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.7357724590600234 [1079] [387,583] 5 hSpCas9 negative selection 1220681
166038018 166038041 2 + 26627737 RPE1 viability after 12 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.025743937849955323 [2792] [655,822] 0 hSpCas9 negative selection 1220682
166051938 166051961 2 + 26627737 RPE1 viability after 12 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.6119397689896193 [1987] [825,805] 4 hSpCas9 negative selection 1220683
166052833 166052856 2 + 26627737 RPE1 viability after 12 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 -0.8713194632201198 [334] [21,77] -5 hSpCas9 negative selection 1220684
166073593 166073616 2 - 26627737 RPE1 viability after 12 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.00971696818705231 [950] [213,302] 0 hSpCas9 negative selection 1220685
165991303 165991326 2 + 26627737 RPE1 viability after 15 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.7058141886627347 [602] [293,262] 4 hSpCas9 negative selection 1302995
166036129 166036152 2 + 26627737 RPE1 viability after 15 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 1.2269426858387091 [1079] [877,557] 7 hSpCas9 negative selection 1302996
166038018 166038041 2 + 26627737 RPE1 viability after 15 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.12577519187044905 [2792] [576,865] -1 hSpCas9 negative selection 1302997
166051938 166051961 2 + 26627737 RPE1 viability after 15 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.7764793780826795 [1987] [1002,924] 5 hSpCas9 negative selection 1302998
166052833 166052856 2 + 26627737 RPE1 viability after 15 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 -1.2931373691835604 [334] [0,74] -7 hSpCas9 negative selection 1302999
166073593 166073616 2 - 26627737 RPE1 viability after 15 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.14496278168248733 [950] [271,321] 1 hSpCas9 negative selection 1303000
165991303 165991326 2 + 26627737 RPE1 viability after 18 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.45467660716393393 [602] [208,237] 3 hSpCas9 negative selection 1385310
166036129 166036152 2 + 26627737 RPE1 viability after 18 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.7641097518240734 [1079] [450,541] 5 hSpCas9 negative selection 1385311
166038018 166038041 2 + 26627737 RPE1 viability after 18 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 0.09154594821749473 [2792] [558,1063] 0 hSpCas9 negative selection 1385312
166051938 166051961 2 + 26627737 RPE1 viability after 18 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.5924522348137076 [1987] [675,950] 4 hSpCas9 negative selection 1385313
166052833 166052856 2 + 26627737 RPE1 viability after 18 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 -2.043275064844088 [334] [19,23] -8 hSpCas9 negative selection 1385314
166073593 166073616 2 - 26627737 RPE1 viability after 18 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.35462731648558354 [950] [259,400] 2 hSpCas9 negative selection 1385315
165991303 165991326 2 + 26627737 HeLa viability after 8 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.07226723902549011 [372] [261,172,101] 0 hSpCas9 negative selection 1467625
166036129 166036152 2 + 26627737 HeLa viability after 8 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 -0.4448117429234246 [898] [404,164,315] -4 hSpCas9 negative selection 1467626
166038018 166038041 2 + 26627737 HeLa viability after 8 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.019454838902905447 [1262] [850,499,356] 0 hSpCas9 negative selection 1467627
166051938 166051961 2 + 26627737 HeLa viability after 8 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.8763702547947193 [683] [851,316,537] 7 hSpCas9 negative selection 1467628
166052833 166052856 2 + 26627737 HeLa viability after 8 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 2.858954125397849 [31] [49,172,70] 9 hSpCas9 negative selection 1467629
166073593 166073616 2 - 26627737 HeLa viability after 8 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 1.721187774357774 [151] [448,155,107] 9 hSpCas9 negative selection 1467630
165991303 165991326 2 + 26627737 HeLa viability after 12 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.2606077971573866 [372] [245,125,189] 2 hSpCas9 negative selection 1549940
166036129 166036152 2 + 26627737 HeLa viability after 12 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 -0.728964738734132 [898] [197,126,356] -6 hSpCas9 negative selection 1549941
166038018 166038041 2 + 26627737 HeLa viability after 12 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.2816874377421579 [1262] [379,416,490] -2 hSpCas9 negative selection 1549942
166051938 166051961 2 + 26627737 HeLa viability after 12 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.9591269016575742 [683] [689,348,634] 7 hSpCas9 negative selection 1549943
166052833 166052856 2 + 26627737 HeLa viability after 12 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 2.0656403787196025 [31] [58,75,28] 9 hSpCas9 negative selection 1549944
166073593 166073616 2 - 26627737 HeLa viability after 12 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 2.2870584237779457 [151] [579,180,179] 9 hSpCas9 negative selection 1549945
165991303 165991326 2 + 26627737 HeLa viability after 15 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.08480029426319201 [372] [177,178,122] 0 hSpCas9 negative selection 1632255
166036129 166036152 2 + 26627737 HeLa viability after 15 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.03354223962201752 [898] [305,427,391] 0 hSpCas9 negative selection 1632256
166038018 166038041 2 + 26627737 HeLa viability after 15 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 0.18571505139810718 [1262] [757,616,359] 1 hSpCas9 negative selection 1632257
166051938 166051961 2 + 26627737 HeLa viability after 15 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 1.0438192748111117 [683] [568,522,634] 7 hSpCas9 negative selection 1632258
166052833 166052856 2 + 26627737 HeLa viability after 15 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 2.092410481542875 [31] [42,29,96] 9 hSpCas9 negative selection 1632259
166073593 166073616 2 - 26627737 HeLa viability after 15 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 1.8153501668254273 [151] [209,218,224] 9 hSpCas9 negative selection 1632260
165991303 165991326 2 + 26627737 HeLa viability after 18 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.13723461314643426 [372] [127,151,122] 1 hSpCas9 negative selection 1714570
166036129 166036152 2 + 26627737 HeLa viability after 18 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.04019532017580141 [898] [200,363,391] 0 hSpCas9 negative selection 1714571
166038018 166038041 2 + 26627737 HeLa viability after 18 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 0.1858330905564214 [1262] [502,517,359] 1 hSpCas9 negative selection 1714572
166051938 166051961 2 + 26627737 HeLa viability after 18 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 1.0663462167685984 [683] [392,440,634] 7 hSpCas9 negative selection 1714573
166052833 166052856 2 + 26627737 HeLa viability after 18 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 2.0390464002574378 [31] [27,20,96] 9 hSpCas9 negative selection 1714574
166073593 166073616 2 - 26627737 HeLa viability after 18 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 1.8597065541409947 [151] [147,188,224] 9 hSpCas9 negative selection 1714575
165991303 165991326 2 + 26627737 HCT116 viability after 6 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 -0.2539700191743328 [593] [96,67] -1 hSpCas9 negative selection 1796885
166036129 166036152 2 + 26627737 HCT116 viability after 6 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 -0.22006014818514819 [637] [98,78] -1 hSpCas9 negative selection 1796886
166038018 166038041 2 + 26627737 HCT116 viability after 6 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 0.13428633199927043 [1684] [418,219] 0 hSpCas9 negative selection 1796887
166051938 166051961 2 + 26627737 HCT116 viability after 6 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.8975241077987546 [1330] [441,360] 5 hSpCas9 negative selection 1796888
166052833 166052856 2 + 26627737 HCT116 viability after 6 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 0.5563820184141293 [190] [38,46] 3 hSpCas9 negative selection 1796889
166073593 166073616 2 - 26627737 HCT116 viability after 6 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.009266720016791713 [566] [90,88] 0 hSpCas9 negative selection 1796890
165991303 165991326 2 + 26627737 HCT116 viability after 8 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.5157309807218557 [185] [192,147,99] 5 hSpCas9 negative selection 1879200
166036129 166036152 2 + 26627737 HCT116 viability after 8 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.04052847773003543 [653] [308,363,436] 0 hSpCas9 negative selection 1879201
166038018 166038041 2 + 26627737 HCT116 viability after 8 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.5414265563319698 [1199] [288,531,537] -6 hSpCas9 negative selection 1879202
166051938 166051961 2 + 26627737 HCT116 viability after 8 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 -0.0621359116098239 [786] [413,407,423] 0 hSpCas9 negative selection 1879203
166052833 166052856 2 + 26627737 HCT116 viability after 8 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 1.3834809208202181 [63] [130,76,68] 9 hSpCas9 negative selection 1879204
166073593 166073616 2 - 26627737 HCT116 viability after 8 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 -0.17043485297769717 [342] [177,239,86] -2 hSpCas9 negative selection 1879205
165991303 165991326 2 + 26627737 HCT116 viability after 9 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 -0.606018058538681 [593] [230,3] -4 hSpCas9 negative selection 1961515
166036129 166036152 2 + 26627737 HCT116 viability after 9 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.6495382245026868 [637] [264,268] 5 hSpCas9 negative selection 1961516
166038018 166038041 2 + 26627737 HCT116 viability after 9 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.3542591496916774 [1684] [585,166] -2 hSpCas9 negative selection 1961517
166051938 166051961 2 + 26627737 HCT116 viability after 9 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.7801698256953056 [1330] [649,578] 5 hSpCas9 negative selection 1961518
166052833 166052856 2 + 26627737 HCT116 viability after 9 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 -0.7746753067198473 [190] [64,1] -5 hSpCas9 negative selection 1961519
166073593 166073616 2 - 26627737 HCT116 viability after 9 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.632641654380045 [566] [470,47] 4 hSpCas9 negative selection 1961520
165991303 165991326 2 + 26627737 HCT116 viability after 12 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 0.7756050080558792 [185] [161,188,151] 7 hSpCas9 negative selection 2043830
166036129 166036152 2 + 26627737 HCT116 viability after 12 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.0511722044851588 [653] [287,508,280] 0 hSpCas9 negative selection 2043831
166038018 166038041 2 + 26627737 HCT116 viability after 12 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.29915726130423526 [1199] [500,569,468] -3 hSpCas9 negative selection 2043832
166051938 166051961 2 + 26627737 HCT116 viability after 12 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.06260572065137793 [786] [337,429,535] 0 hSpCas9 negative selection 2043833
166052833 166052856 2 + 26627737 HCT116 viability after 12 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 1.1623153374063384 [63] [20,132,77] 8 hSpCas9 negative selection 2043834
166073593 166073616 2 - 26627737 HCT116 viability after 12 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 -0.10733240833826625 [342] [212,167,116] -1 hSpCas9 negative selection 2043835
165991303 165991326 2 + 26627737 HCT116 viability after 15 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 1.1905193089764807 [185] [341,211,189] 8 hSpCas9 negative selection 2126145
166036129 166036152 2 + 26627737 HCT116 viability after 15 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.03396392472426224 [653] [524,451,195] 0 hSpCas9 negative selection 2126146
166038018 166038041 2 + 26627737 HCT116 viability after 15 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.14357674513757313 [1199] [507,848,501] -1 hSpCas9 negative selection 2126147
166051938 166051961 2 + 26627737 HCT116 viability after 15 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 0.432190588493935 [786] [502,661,650] 4 hSpCas9 negative selection 2126148
166052833 166052856 2 + 26627737 HCT116 viability after 15 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 0.2874095277648727 [63] [53,62,18] 3 hSpCas9 negative selection 2126149
166073593 166073616 2 - 26627737 HCT116 viability after 15 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 0.03500338038434153 [342] [179,319,103] 0 hSpCas9 negative selection 2126150
165991303 165991326 2 + 26627737 HCT116 viability after 18 days TTTGTCACCCGGTCATAGGAAGG SCN1A ENSG00000144285 1.1190056173771925 [185] [206,206,169] 8 hSpCas9 negative selection 2208460
166036129 166036152 2 + 26627737 HCT116 viability after 18 days TGGTACAGTCACAGTAAGACTGG SCN1A ENSG00000144285 0.5102582308803143 [653] [463,615,250] 4 hSpCas9 negative selection 2208461
166038018 166038041 2 + 26627737 HCT116 viability after 18 days AGACGATGATGGCCAAGACGAGG SCN1A ENSG00000144285 -0.12574290891529616 [1199] [592,447,560] -1 hSpCas9 negative selection 2208462
166051938 166051961 2 + 26627737 HCT116 viability after 18 days CTGAGAGCTTCTTCACAGACTGG SCN1A ENSG00000144285 -0.1258523931753206 [786] [283,315,452] -1 hSpCas9 negative selection 2208463
166052833 166052856 2 + 26627737 HCT116 viability after 18 days TATCTAACCTTGCTCTCACCTGG SCN1A ENSG00000144285 0.9615781679109368 [63] [57,101,15] 7 hSpCas9 negative selection 2208464
166073593 166073616 2 - 26627737 HCT116 viability after 18 days CAAACAGTGCTTGTACCACCAGG SCN1A ENSG00000144285 -0.0233204805924426 [342] [202,210,67] 0 hSpCas9 negative selection 2208465
166093387 166093410 2 + 25494202 A375 resistance to PLX-4720 (puromycin) GGAGTGCAGTGGCGTGATCTGGG SCN1A ENSG00000144285 1.5299201678265226 [5,69] [1,47] 6 dCas9-VP64 positive selection 2386467
166073923 166073946 2 + 25494202 A375 resistance to PLX-4720 (puromycin) GGCCTTAATCAAAGTACATTAGG SCN1A ENSG00000144285 0.23711169238095886 [388,266] [117,48] 1 dCas9-VP64 positive selection 2404831
166073980 166074003 2 + 25494202 A375 resistance to PLX-4720 (puromycin) TCTGTGACACACCCAGAAGATGG SCN1A ENSG00000144285 0.5993913218233191 [334,122] [20,133] 2 dCas9-VP64 positive selection 2404832
166073895 166073918 2 - 25494202 A375 resistance to PLX-4720 (puromycin) TGAACCACTTTTAAAACTCATGG SCN1A ENSG00000144285 0.9413396693616795 [125,152] [74,40] 4 dCas9-VP64 positive selection 2404833
166124355 166124378 2 - 25494202 A375 resistance to PLX-4720 (puromycin) GGGGTTTCACTATGTTGGCCCGG SCN1A ENSG00000144285 -1.5948665931662949 [72,13] [3,0] -8 dCas9-VP64 positive selection 2426189
166117786 166117809 2 + 25494202 A375 resistance to PLX-4720 (puromycin) GGAGTTCAGCCTGGCCAACATAG SCN1A ENSG00000144285 6.570119908559863 [446,222] [12631,903] 9 dCas9-VP64 positive selection 2455654
166093387 166093410 2 + 25494202 A375 resistance to PLX-4720 (zeocin) GGAGTGCAGTGGCGTGATCTGGG SCN1A ENSG00000144285 0.46408056547853904 [52,55] [23,24] 3 dCas9-VP64 positive selection 2481722
166073923 166073946 2 + 25494202 A375 resistance to PLX-4720 (zeocin) GGCCTTAATCAAAGTACATTAGG SCN1A ENSG00000144285 0.1032328866864336 [224,74] [77,28] 0 dCas9-VP64 positive selection 2500086
166073980 166074003 2 + 25494202 A375 resistance to PLX-4720 (zeocin) TCTGTGACACACCCAGAAGATGG SCN1A ENSG00000144285 0.7180742902627736 [238,107] [79,106] 5 dCas9-VP64 positive selection 2500087
166073895 166073918 2 - 25494202 A375 resistance to PLX-4720 (zeocin) TGAACCACTTTTAAAACTCATGG SCN1A ENSG00000144285 -0.2853885288363536 [35,273] [19,59] -3 dCas9-VP64 positive selection 2500088
166124355 166124378 2 - 25494202 A375 resistance to PLX-4720 (zeocin) GGGGTTTCACTATGTTGGCCCGG SCN1A ENSG00000144285 -1.232765897461272 [137,17] [14,5] -9 dCas9-VP64 positive selection 2521444
166117786 166117809 2 + 25494202 A375 resistance to PLX-4720 (zeocin) GGAGTTCAGCCTGGCCAACATAG SCN1A ENSG00000144285 0.905371279890363 [221,293] [157,156] 6 dCas9-VP64 positive selection 2550909
166047754 166047777 2 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity ACTTGCAGCCAATGTCCAGAGGG SCN1A ENSG00000144285 0.10067023276426718 [3,3] [4,2] 2 hSpCas9 positive selection 3018958
166056416 166056439 2 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CATTCTTTGTCCAATCAGGAGGG SCN1A ENSG00000144285 0.23475397679750754 [5,5] [5,5] 5 hSpCas9 positive selection 3018959
166045202 166045225 2 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 0.4063836416648986 [4,4] [4,6] 8 hSpCas9 positive selection 3018960
166043831 166043854 2 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GCAACCTGAGTCAGACCAGTAGG SCN1A ENSG00000144285 0.492161693540127 [3,3] [2,5] 8 hSpCas9 positive selection 3018961
166047754 166047777 2 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity ACTTGCAGCCAATGTCCAGAGGG SCN1A ENSG00000144285 0.07992264000354825 [3,3] [4,1] 1 hSpCas9 positive selection 3086816
166056416 166056439 2 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CATTCTTTGTCCAATCAGGAGGG SCN1A ENSG00000144285 0.2770536059660429 [5,5] [7,2] 5 hSpCas9 positive selection 3086817
166045202 166045225 2 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 0.013418725775714901 [4,4] [5,2] 0 hSpCas9 positive selection 3086818
166043831 166043854 2 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GCAACCTGAGTCAGACCAGTAGG SCN1A ENSG00000144285 -0.28337986025436185 [3,3] [2,0] -4 hSpCas9 positive selection 3086819
166054739 166054762 + 24336571 A375 resistance to PLX after 7 days AAAAGTATATATTCCTGTGAAGG SCN1A ENSG00000144285 -0.12268733141548532 [16,18] [16,15] -4 hSpCas9 positive selection 3142860
166054712 166054735 - 24336571 A375 resistance to PLX after 7 days CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.2273606246657096 [2,1] [2,2] 6 hSpCas9 positive selection 3142861
166051889 166051912 - 24336571 A375 resistance to PLX after 7 days CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.08112124949698929 [25,28] [29,28] 3 hSpCas9 positive selection 3142862
166051965 166051988 + 24336571 A375 resistance to PLX after 7 days GGGCTCCCACAATGGTTTTCAGG SCN1A ENSG00000144285 -0.018576886867843312 [16,16] [16,15] 0 hSpCas9 positive selection 3142863
166054752 166054775 - 24336571 A375 resistance to PLX after 7 days GTTTTCAGATACACCTTCACAGG SCN1A ENSG00000144285 -0.18163103340681785 [31,31] [25,28] -6 hSpCas9 positive selection 3142864
166051971 166051994 - 24336571 A375 resistance to PLX after 7 days TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.14059442609132716 [13,13] [12,11] -4 hSpCas9 positive selection 3142866
166054739 166054762 + 24336571 A375 resistance to PLX after 14 days AAAAGTATATATTCCTGTGAAGG SCN1A ENSG00000144285 -0.708402950274449 [21,24] [4,6] -8 hSpCas9 positive selection 3200653
166054712 166054735 - 24336571 A375 resistance to PLX after 14 days CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.6323833904507539 [1,2] [1,1] 5 hSpCas9 positive selection 3200654
166051889 166051912 - 24336571 A375 resistance to PLX after 14 days CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 -0.5219515748156908 [27,25] [8,7] -6 hSpCas9 positive selection 3200655
166051965 166051988 + 24336571 A375 resistance to PLX after 14 days GGGCTCCCACAATGGTTTTCAGG SCN1A ENSG00000144285 -0.3600550132860748 [29,18] [6,9] -4 hSpCas9 positive selection 3200656
166054752 166054775 - 24336571 A375 resistance to PLX after 14 days GTTTTCAGATACACCTTCACAGG SCN1A ENSG00000144285 0.4296918814715216 [30,25] [17,17] 4 hSpCas9 positive selection 3200657
166051971 166051994 - 24336571 A375 resistance to PLX after 14 days TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.5172058720254258 [11,11] [3,2] -6 hSpCas9 positive selection 3200659
166054739 166054762 + 24336571 A375 viability after 7 days AAAAGTATATATTCCTGTGAAGG SCN1A ENSG00000144285 -0.3549214100875838 [24] [16,18] -5 hSpCas9 negative selection 3258446
166054712 166054735 - 24336571 A375 viability after 7 days CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 -0.14185729208511288 [2] [2,1] -2 hSpCas9 negative selection 3258447
166051889 166051912 - 24336571 A375 viability after 7 days CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.523591022279357 [19] [25,28] 7 hSpCas9 negative selection 3258448
166051965 166051988 + 24336571 A375 viability after 7 days GGGCTCCCACAATGGTTTTCAGG SCN1A ENSG00000144285 -0.0698768235609924 [18] [16,16] -1 hSpCas9 negative selection 3258449
166054752 166054775 - 24336571 A375 viability after 7 days GTTTTCAGATACACCTTCACAGG SCN1A ENSG00000144285 -0.19328470071367487 [37] [31,31] -3 hSpCas9 negative selection 3258450
166051971 166051994 - 24336571 A375 viability after 7 days TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.2717204780007506 [11] [13,13] 4 hSpCas9 negative selection 3258452
166054739 166054762 + 24336571 A375 viability after 14 days AAAAGTATATATTCCTGTGAAGG SCN1A ENSG00000144285 0.028678725582924725 [24] [21,24] 0 hSpCas9 negative selection 3316239
166054712 166054735 - 24336571 A375 viability after 14 days CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 -0.24153777368246976 [2] [1,2] -3 hSpCas9 negative selection 3316240
166051889 166051912 - 24336571 A375 viability after 14 days CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.4823567715087672 [19] [27,25] 6 hSpCas9 negative selection 3316241
166051965 166051988 + 24336571 A375 viability after 14 days GGGCTCCCACAATGGTTTTCAGG SCN1A ENSG00000144285 0.4553836847815578 [18] [29,18] 6 hSpCas9 negative selection 3316242
166054752 166054775 - 24336571 A375 viability after 14 days GTTTTCAGATACACCTTCACAGG SCN1A ENSG00000144285 -0.3331820087826578 [37] [30,25] -4 hSpCas9 negative selection 3316243
166051971 166051994 - 24336571 A375 viability after 14 days TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.13730634397991326 [11] [11,11] 1 hSpCas9 negative selection 3316245
166048932 166048955 2 - 27383988 293T resistance to West Nile virus (flavivirus) AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.9025451253325543 [285,285] [0,0] -6 hSpCas9 positive selection 3391418
166054653 166054676 2 + 27383988 293T resistance to West Nile virus (flavivirus) GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.2915419267837481 [124,124] [0,0] 1 hSpCas9 positive selection 3391419
166054712 166054735 2 - 27383988 293T resistance to West Nile virus (flavivirus) CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.009398698002249677 [151,151] [0,0] 0 hSpCas9 positive selection 3391420
166047754 166047777 2 - 26780180 HT29 viability (Avana library 4 designs) ACTTGCAGCCAATGTCCAGAGGG SCN1A ENSG00000144285 1.70537482299641 [] [] 6 hSpCas9 negative selection 3457385
166056415 166056438 2 + 26780180 HT29 viability (Avana library 4 designs) CATTCTTTGTCCAATCAGGAGGG SCN1A ENSG00000144285 -0.314386759864368 [] [] -5 hSpCas9 negative selection 3457386
166045202 166045225 2 - 26780180 HT29 viability (Avana library 4 designs) CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 0.284587193272526 [] [] 1 hSpCas9 negative selection 3457387
166043831 166043854 2 - 26780180 HT29 viability (Avana library 4 designs) GCAACCTGAGTCAGACCAGTAGG SCN1A ENSG00000144285 1.91332029292917 [] [] 7 hSpCas9 negative selection 3457388
166047754 166047777 2 - 26780180 A375 viability (Avana lentiCRISPRv2) ACTTGCAGCCAATGTCCAGAGGG SCN1A ENSG00000144285 3.50042731208767 [] [] 5 hSpCas9 negative selection 3556315
166056415 166056438 2 + 26780180 A375 viability (Avana lentiCRISPRv2) CATTCTTTGTCCAATCAGGAGGG SCN1A ENSG00000144285 -2.4011865083782302 [] [] -3 hSpCas9 negative selection 3556316
166043831 166043854 2 - 26780180 A375 viability (Avana lentiCRISPRv2) GCAACCTGAGTCAGACCAGTAGG SCN1A ENSG00000144285 2.39211608468727 [] [] 3 hSpCas9 negative selection 3556317
166045202 166045225 2 - 26780180 A375 viability (Avana lentiCRISPRv2) CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 -1.44519565297746 [] [] -2 hSpCas9 negative selection 3556318
166046857 166046880 2 + 26780180 A375 viability (Avana lentiCRISPRv2) ATTCTGTTCCTCGTAGGCCATGG SCN1A ENSG00000144285 2.61751888105386 [] [] 4 hSpCas9 negative selection 3556319
166058611 166058634 2 + 26780180 A375 viability (Avana lentiCRISPRv2) GAAGGGAGTTAAAATGTACAGGG SCN1A ENSG00000144285 0.0665251806550429 [] [] 0 hSpCas9 negative selection 3556320
166047754 166047777 2 - 26780180 A375 viability (Avana lentiGuide) ACTTGCAGCCAATGTCCAGAGGG SCN1A ENSG00000144285 -5.07840681660881 [] [] -8 hSpCas9 negative selection 3664974
166056415 166056438 2 + 26780180 A375 viability (Avana lentiGuide) CATTCTTTGTCCAATCAGGAGGG SCN1A ENSG00000144285 -4.53087192625305 [] [] -7 hSpCas9 negative selection 3664975
166043831 166043854 2 - 26780180 A375 viability (Avana lentiGuide) GCAACCTGAGTCAGACCAGTAGG SCN1A ENSG00000144285 -3.05494801377205 [] [] -5 hSpCas9 negative selection 3664976
166045202 166045225 2 - 26780180 A375 viability (Avana lentiGuide) CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 -5.75698947522242 [] [] -8 hSpCas9 negative selection 3664977
166046857 166046880 2 + 26780180 A375 viability (Avana lentiGuide) ATTCTGTTCCTCGTAGGCCATGG SCN1A ENSG00000144285 7.18807092368183 [] [] 5 hSpCas9 negative selection 3664978
166058611 166058634 2 + 26780180 A375 viability (Avana lentiGuide) GAAGGGAGTTAAAATGTACAGGG SCN1A ENSG00000144285 -1.35644606027502 [] [] -2 hSpCas9 negative selection 3664979
166047754 166047777 2 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ACTTGCAGCCAATGTCCAGAGGG SCN1A ENSG00000144285 0.05368660606100001 [4] [4,4] 1 hSpCas9 positive selection 3773581
166056415 166056438 2 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CATTCTTTGTCCAATCAGGAGGG SCN1A ENSG00000144285 -0.2509562075105187 [6] [5,5] -4 hSpCas9 positive selection 3773582
166043831 166043854 2 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCAACCTGAGTCAGACCAGTAGG SCN1A ENSG00000144285 -0.02937147014542829 [3] [4,2] 0 hSpCas9 positive selection 3773583
166045202 166045225 2 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 0.07247058083216562 [6] [6,6] 1 hSpCas9 positive selection 3773584
166046857 166046880 2 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ATTCTGTTCCTCGTAGGCCATGG SCN1A ENSG00000144285 0.154492299535777 [5] [6,4] 4 hSpCas9 positive selection 3773585
166058611 166058634 2 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GAAGGGAGTTAAAATGTACAGGG SCN1A ENSG00000144285 0.06452511548369078 [6] [6,6] 1 hSpCas9 positive selection 3773586
166047754 166047777 2 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ACTTGCAGCCAATGTCCAGAGGG SCN1A ENSG00000144285 0.45453544544415575 [5] [7,6] 9 hSpCas9 positive selection 3882188
166056415 166056438 2 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CATTCTTTGTCCAATCAGGAGGG SCN1A ENSG00000144285 0.18764920012826614 [6] [7,5] 4 hSpCas9 positive selection 3882189
166043831 166043854 2 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCAACCTGAGTCAGACCAGTAGG SCN1A ENSG00000144285 0.38284945916503804 [4] [5,5] 9 hSpCas9 positive selection 3882190
166045202 166045225 2 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CTAAGGAAAGAAGAAATCGGAGG SCN1A ENSG00000144285 0.3405935122150003 [6] [7,6] 8 hSpCas9 positive selection 3882191
166046857 166046880 2 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ATTCTGTTCCTCGTAGGCCATGG SCN1A ENSG00000144285 0.14474157959571893 [5] [3,5] 3 hSpCas9 positive selection 3882192
166058611 166058634 2 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GAAGGGAGTTAAAATGTACAGGG SCN1A ENSG00000144285 -0.3005757382447567 [4] [3,1] -4 hSpCas9 positive selection 3882193
166048932 166048955 2 - 26780180 A375 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 0.777588115429239 [] [] 3 hSpCas9 negative selection 3992214
166054712 166054735 2 - 26780180 A375 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 1.19643660305488 [] [] 6 hSpCas9 negative selection 3992215
166051889 166051912 2 - 26780180 A375 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.145645878976828 [] [] 0 hSpCas9 negative selection 3992216
166054653 166054676 2 + 26780180 A375 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.84149109906558 [] [] 3 hSpCas9 negative selection 3992217
166048914 166048937 2 + 26780180 A375 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.340206534138015 [] [] 0 hSpCas9 negative selection 3992218
166051971 166051994 2 - 26780180 A375 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.858365824759695 [] [] 3 hSpCas9 negative selection 3992219
166048932 166048955 2 - 26780180 HT29 viability (GeCKOv2 library) AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 1.71196577130049 [] [] 8 hSpCas9 negative selection 4100180
166054712 166054735 2 - 26780180 HT29 viability (GeCKOv2 library) CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 1.08073670674911 [] [] 5 hSpCas9 negative selection 4100181
166051889 166051912 2 - 26780180 HT29 viability (GeCKOv2 library) CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.638988660455504 [] [] 2 hSpCas9 negative selection 4100182
166054653 166054676 2 + 26780180 HT29 viability (GeCKOv2 library) GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 1.2878536110601 [] [] 6 hSpCas9 negative selection 4100183
166048914 166048937 2 + 26780180 HT29 viability (GeCKOv2 library) GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.413851565835474 [] [] 1 hSpCas9 negative selection 4100184
166051971 166051994 2 - 26780180 HT29 viability (GeCKOv2 library) TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.563213569169658 [] [] 2 hSpCas9 negative selection 4100185
166054739 166054762 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) AAAAGTATATATTCCTGTGAAGG SCN1A ENSG00000144285 0.04758524165846614 [4] [3,2] 1 hSpCas9 positive selection 4168647
166054712 166054735 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.6983142528968276 [0] [0,0] 9 hSpCas9 positive selection 4168648
166051889 166051912 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.007127236686689797 [4] [3,2] 0 hSpCas9 positive selection 4168649
166051965 166051988 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GGGCTCCCACAATGGTTTTCAGG SCN1A ENSG00000144285 0.3220257743873797 [4] [3,2] 7 hSpCas9 positive selection 4168650
166054752 166054775 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GTTTTCAGATACACCTTCACAGG SCN1A ENSG00000144285 0.2478957432927682 [4] [3,4] 6 hSpCas9 positive selection 4168651
166051971 166051994 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.05923267800659256 [3] [2,1] 1 hSpCas9 positive selection 4168653
166054739 166054762 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) AAAAGTATATATTCCTGTGAAGG SCN1A ENSG00000144285 1.1292829245263052 [4] [3,3,4,4] 8 hSpCas9 positive selection 4232669
166054712 166054735 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 -0.13099724777042815 [2] [0,0,1,0] -2 hSpCas9 positive selection 4232670
166051889 166051912 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 1.2062972373735574 [4] [3,3,5,4] 8 hSpCas9 positive selection 4232671
166051965 166051988 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GGGCTCCCACAATGGTTTTCAGG SCN1A ENSG00000144285 1.2212463771387818 [3] [4,2,4,3] 8 hSpCas9 positive selection 4232672
166054752 166054775 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GTTTTCAGATACACCTTCACAGG SCN1A ENSG00000144285 0.8402725103118238 [4] [2,4,2,3] 5 hSpCas9 positive selection 4232673
166051971 166051994 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.8554890284903768 [3] [2,0,2,3] 5 hSpCas9 positive selection 4232675
166048914 166048937 2 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.15724415469660302 [0] [0,0] -3 hSpCas9 positive selection 4296604
166051889 166051912 2 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.1609549787482048 [2] [2,1] 3 hSpCas9 positive selection 4296605
166051971 166051994 2 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.47583372881044506 [3] [3,2] 8 hSpCas9 positive selection 4296606
166048932 166048955 2 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 0.13445515964112945 [3] [3,2] 2 hSpCas9 positive selection 4360858
166054653 166054676 2 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.2928456341514495 [2] [1,0] -6 hSpCas9 positive selection 4360859
166054712 166054735 2 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.12807150543244156 [2] [3,1] 2 hSpCas9 positive selection 4360860
166039451 166039473 2 - 27760321 OCIAML3 viability TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.759304591729624 [399,360] [494,513] 8 hSpCas9 negative selection 4437180
166039479 166039501 2 - 27760321 OCIAML3 viability TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.20552415561812548 [312,315] [161,281] -2 hSpCas9 negative selection 4437181
166042356 166042378 2 + 27760321 OCIAML3 viability TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 0.48003170872745826 [202,181] [151,284] 6 hSpCas9 negative selection 4437182
166043796 166043818 2 - 27760321 OCIAML3 viability TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.19220387150266005 [577,472] [402,550] 2 hSpCas9 negative selection 4437183
166047653 166047675 2 - 27760321 OCIAML3 viability TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 -0.5041079275680043 [240,195] [118,120] -5 hSpCas9 negative selection 4437184
166039451 166039473 2 - 27760321 OCIAML2 viability TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.4412311998695333 [399,360] [316,549] 6 hSpCas9 negative selection 4520643
166039479 166039501 2 - 27760321 OCIAML2 viability TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.210050988037278 [312,315] [193,255] -3 hSpCas9 negative selection 4520644
166042356 166042378 2 + 27760321 OCIAML2 viability TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 -0.7770311249092179 [202,181] [82,100] -7 hSpCas9 negative selection 4520645
166043796 166043818 2 - 27760321 OCIAML2 viability TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.5092770243424323 [577,472] [545,675] 7 hSpCas9 negative selection 4520646
166047653 166047675 2 - 27760321 OCIAML2 viability TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 0.18916566915361377 [240,195] [171,237] 2 hSpCas9 negative selection 4520647
166039451 166039473 2 - 27760321 MV411 viability TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.4172180135776243 [399,360] [318,358] 3 hSpCas9 negative selection 4604106
166039479 166039501 2 - 27760321 MV411 viability TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 0.197945763909448 [312,315] [160,355] 1 hSpCas9 negative selection 4604107
166042356 166042378 2 + 27760321 MV411 viability TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 -0.14257236015513852 [202,181] [42,222] -1 hSpCas9 negative selection 4604108
166043796 166043818 2 - 27760321 MV411 viability TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 1.6811330845579784 [577,472] [1562,420] 9 hSpCas9 negative selection 4604109
166047653 166047675 2 - 27760321 MV411 viability TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 0.20395843035862626 [240,195] [195,118] 1 hSpCas9 negative selection 4604110
166039451 166039473 2 - 27760321 HL60 viability TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.6383914346632633 [399,360] [412,557] 7 hSpCas9 negative selection 4687569
166039479 166039501 2 - 27760321 HL60 viability TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.4077523411194363 [312,315] [189,198] -4 hSpCas9 negative selection 4687570
166042356 166042378 2 + 27760321 HL60 viability TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 -0.09551106795171393 [202,181] [146,146] -1 hSpCas9 negative selection 4687571
166043796 166043818 2 - 27760321 HL60 viability TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.21891170196766374 [577,472] [468,526] 2 hSpCas9 negative selection 4687572
166047653 166047675 2 - 27760321 HL60 viability TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 -0.7797970359131612 [240,195] [133,70] -7 hSpCas9 negative selection 4687573
166039451 166039473 2 - 27760321 HT1080 viability TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.08892544605937992 [360,281] [140,130] 0 hSpCas9 negative selection 4771032
166039479 166039501 2 - 27760321 HT1080 viability TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.8083669832273577 [315,246] [85,39] -3 hSpCas9 negative selection 4771033
166042356 166042378 2 + 27760321 HT1080 viability TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 0.11907213559724505 [181,141] [92,44] 0 hSpCas9 negative selection 4771034
166043796 166043818 2 - 27760321 HT1080 viability TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.457241964894332 [472,368] [224,235] 2 hSpCas9 negative selection 4771035
166047653 166047675 2 - 27760321 HT1080 viability TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 2.1105237737037945 [195,152] [430,156] 9 hSpCas9 negative selection 4771036
166039451 166039473 2 - 27760321 HT29 viability after 7 days TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 -0.03144379712408815 [360,281] [392,407,409] 0 hSpCas9 negative selection 4854495
166039479 166039501 2 - 27760321 HT29 viability after 7 days TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.6642499937238926 [315,246] [319,214,164] -7 hSpCas9 negative selection 4854496
166042356 166042378 2 + 27760321 HT29 viability after 7 days TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 -0.001241416899501191 [181,141] [401,147,104] 0 hSpCas9 negative selection 4854497
166043796 166043818 2 - 27760321 HT29 viability after 7 days TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.2243736264225556 [472,368] [734,518,655] 3 hSpCas9 negative selection 4854498
166047653 166047675 2 - 27760321 HT29 viability after 7 days TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 0.06435464153304593 [195,152] [301,142,266] 1 hSpCas9 negative selection 4854499
166039451 166039473 2 - 27760321 HT29 viability after 25 days TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.2239047087576239 [360,281] [314,686,275] 2 hSpCas9 negative selection 4937958
166039479 166039501 2 - 27760321 HT29 viability after 25 days TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.5837326422083837 [315,246] [258,174,205] -5 hSpCas9 negative selection 4937959
166042356 166042378 2 + 27760321 HT29 viability after 25 days TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 0.45115759415794343 [181,141] [229,90,460] 5 hSpCas9 negative selection 4937960
166043796 166043818 2 - 27760321 HT29 viability after 25 days TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.41045124154452295 [472,368] [558,658,711] 4 hSpCas9 negative selection 4937961
166047653 166047675 2 - 27760321 HT29 viability after 25 days TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 0.07799179358462849 [195,152] [248,149,231] 0 hSpCas9 negative selection 4937962
166039451 166039473 2 - 27760321 HT29 viability after 22 days TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.6212660075857261 [360,281] [491,586,638] 7 hSpCas9 negative selection 5021421
166039479 166039501 2 - 27760321 HT29 viability after 22 days TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.7183295640524783 [315,246] [201,226,163] -6 hSpCas9 negative selection 5021422
166042356 166042378 2 + 27760321 HT29 viability after 22 days TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 0.27023350861379347 [181,141] [234,248,192] 3 hSpCas9 negative selection 5021423
166043796 166043818 2 - 27760321 HT29 viability after 22 days TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.23632095147837268 [472,368] [555,628,534] 2 hSpCas9 negative selection 5021424
166047653 166047675 2 - 27760321 HT29 viability after 22 days TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 -0.6798783095368661 [195,152] [127,93,155] -5 hSpCas9 negative selection 5021425
166039451 166039473 2 - 27760321 HT29 viability after 19 days TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.023848752265659162 [360,281] [488,502,149] 0 hSpCas9 negative selection 5104884
166039479 166039501 2 - 27760321 HT29 viability after 19 days TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.6654823121795237 [315,246] [364,169,94] -5 hSpCas9 negative selection 5104885
166042356 166042378 2 + 27760321 HT29 viability after 19 days TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 0.7342558123082795 [181,141] [356,169,398] 7 hSpCas9 negative selection 5104886
166043796 166043818 2 - 27760321 HT29 viability after 19 days TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.3572189505363742 [472,368] [572,782,493] 3 hSpCas9 negative selection 5104887
166047653 166047675 2 - 27760321 HT29 viability after 19 days TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 -0.5589593332605709 [195,152] [93,65,237] -5 hSpCas9 negative selection 5104888
166039451 166039473 2 - 27760321 HT29 viability after 16 days TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.5866341785623661 [360,281] [526,511,580] 6 hSpCas9 negative selection 5188347
166039479 166039501 2 - 27760321 HT29 viability after 16 days TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.7247892583335676 [315,246] [234,110,231] -6 hSpCas9 negative selection 5188348
166042356 166042378 2 + 27760321 HT29 viability after 16 days TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 -0.4017242411458566 [181,141] [177,37,201] -4 hSpCas9 negative selection 5188349
166043796 166043818 2 - 27760321 HT29 viability after 16 days TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.3807611929918021 [472,368] [610,592,635] 4 hSpCas9 negative selection 5188350
166047653 166047675 2 - 27760321 HT29 viability after 16 days TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 -1.1212637187593086 [195,152] [157,38,79] -7 hSpCas9 negative selection 5188351
166039451 166039473 2 - 27760321 HT29 viability after 13 days TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 0.4080789804581597 [360,281] [525,486,472] 5 hSpCas9 negative selection 5271810
166039479 166039501 2 - 27760321 HT29 viability after 13 days TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.45546642057164427 [315,246] [315,256,146] -5 hSpCas9 negative selection 5271811
166042356 166042378 2 + 27760321 HT29 viability after 13 days TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 0.06670045745995079 [181,141] [117,213,254] 0 hSpCas9 negative selection 5271812
166043796 166043818 2 - 27760321 HT29 viability after 13 days TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.8553545018283673 [472,368] [771,945,929] 9 hSpCas9 negative selection 5271813
166047653 166047675 2 - 27760321 HT29 viability after 13 days TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 -0.6463425907079061 [195,152] [238,57,92] -6 hSpCas9 negative selection 5271814
166039451 166039473 2 - 27760321 HT29 viability after 10 days TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 -0.17127500174248733 [360,281] [357,226,477] -2 hSpCas9 negative selection 5355273
166039479 166039501 2 - 27760321 HT29 viability after 10 days TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 -0.6639363207482114 [315,246] [378,60,220] -7 hSpCas9 negative selection 5355274
166042356 166042378 2 + 27760321 HT29 viability after 10 days TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 0.0009539473718329639 [181,141] [343,155,107] 0 hSpCas9 negative selection 5355275
166043796 166043818 2 - 27760321 HT29 viability after 10 days TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.1030826195637064 [472,368] [490,685,520] 1 hSpCas9 negative selection 5355276
166047653 166047675 2 - 27760321 HT29 viability after 10 days TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 -1.2274193098255137 [195,152] [75,117,85] -8 hSpCas9 negative selection 5355277
166039451 166039473 2 - 27760321 MOLM13 viability TTGGACTCGCCAATGTGGAAGG SCN1A ENSG00000144285 1.1141070974287537 [399,360] [796,180] 7 hSpCas9 negative selection 5438736
166039479 166039501 2 - 27760321 MOLM13 viability TTTATTGTGACGCTTAGCCTGG SCN1A ENSG00000144285 0.790971028879722 [312,315] [238,366] 5 hSpCas9 negative selection 5438737
166042356 166042378 2 + 27760321 MOLM13 viability TAGAAAGTCCATGGAAACGTGG SCN1A ENSG00000144285 1.0490441843157294 [202,181] [298,160] 7 hSpCas9 negative selection 5438738
166043796 166043818 2 - 27760321 MOLM13 viability TGGCAGTGTTTCCAGCGAATGG SCN1A ENSG00000144285 0.5934231246815229 [577,472] [570,337] 4 hSpCas9 negative selection 5438739
166047653 166047675 2 - 27760321 MOLM13 viability TTGTTTCGACTAATGACTCAGG SCN1A ENSG00000144285 -1.5677127776683522 [240,195] [69,16] -7 hSpCas9 negative selection 5438740
166073286 166073309 2 + 27661255 K562 viability GTTGGTGCTACAACAGTCCAAGG SCN1A ENSG00000144285 0.0967656538841144 [2910,3442] [2980,2470] 3 dCas9-KRAB negative selection 5509627
166073569 166073592 2 + 27661255 K562 viability GTGAAGAAGTTGAAGCTGTCAGG SCN1A ENSG00000144285 0.10726186010280059 [1624,1910] [1606,1439] 4 dCas9-KRAB negative selection 5509628
166073136 166073159 2 - 27661255 K562 viability GCACCATGACAAATAAAAAGAGG SCN1A ENSG00000144285 -0.245981743797621 [638,525] [491,309] -6 dCas9-KRAB negative selection 5509629
166073339 166073362 2 - 27661255 K562 viability GAAAGTGAGTGTTTTTTATCAGG SCN1A ENSG00000144285 -0.0036036344185204072 [508,566] [483,379] 0 dCas9-KRAB negative selection 5509630
166048914 166048937 2 + 27260156 BXPC3 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.6203989335482603 [23] [37,52,22,38] 9 hSpCas9 negative selection 5569064
166051889 166051912 2 - 27260156 BXPC3 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.36422692800390993 [370] [413,497,558,537] 7 hSpCas9 negative selection 5569065
166051971 166051994 2 - 27260156 BXPC3 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.04787275553574676 [460] [432,415,520,650] 1 hSpCas9 negative selection 5569066
166048932 166048955 2 - 27260156 BXPC3 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.027813567164119535 [628] [626,606,776,560] 0 hSpCas9 negative selection 5633318
166054653 166054676 2 + 27260156 BXPC3 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.3087396475867029 [223] [343,279,262,261] 6 hSpCas9 negative selection 5633319
166054712 166054735 2 - 27260156 BXPC3 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.22174838378801692 [330] [435,345,357,479] 5 hSpCas9 negative selection 5633320
166048914 166048937 2 + 27260156 A673 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.41360155149693334 [23] [32,37,25,56] 8 hSpCas9 negative selection 5690315
166051889 166051912 2 - 27260156 A673 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.0370368971282915 [370] [444,416,470,495] 0 hSpCas9 negative selection 5690316
166051971 166051994 2 - 27260156 A673 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.001350078325864621 [460] [592,455,608,559] 0 hSpCas9 negative selection 5690317
166048932 166048955 2 - 27260156 A673 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.20502088711856972 [628] [686,583,707,644] -5 hSpCas9 negative selection 5754569
166054653 166054676 2 + 27260156 A673 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.029539449712548294 [223] [292,305,214,240] 0 hSpCas9 negative selection 5754570
166054712 166054735 2 - 27260156 A673 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 -0.1189338070369994 [330] [465,340,302,365] -3 hSpCas9 negative selection 5754571
166048914 166048937 2 + 27260156 A375 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.06040304646584982 [23] [26,9,21,43] -1 hSpCas9 negative selection 5811566
166051889 166051912 2 - 27260156 A375 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.26596722425631497 [370] [585,542,530,435] 4 hSpCas9 negative selection 5811567
166051971 166051994 2 - 27260156 A375 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.3288682225434879 [460] [967,817,507,456] 5 hSpCas9 negative selection 5811568
166048932 166048955 2 - 27260156 A375 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 0.049536433307817984 [628] [888,807,727,635] 0 hSpCas9 negative selection 5875820
166054653 166054676 2 + 27260156 A375 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.07727016964191757 [223] [336,274,276,220] 1 hSpCas9 negative selection 5875821
166054712 166054735 2 - 27260156 A375 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.5251517698583835 [330] [657,504,581,480] 7 hSpCas9 negative selection 5875822
166048914 166048937 2 + 27260156 COLO741 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.1490573560180355 [23] [18,18,42] -3 hSpCas9 negative selection 5932817
166051889 166051912 2 - 27260156 COLO741 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.34314923665551184 [370] [513,632,644] 7 hSpCas9 negative selection 5932818
166051971 166051994 2 - 27260156 COLO741 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.19102383541576118 [460] [733,797,501] 4 hSpCas9 negative selection 5932819
166048932 166048955 2 - 27260156 COLO741 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.47873203389192115 [628] [592,626,514] -7 hSpCas9 negative selection 5997071
166054653 166054676 2 + 27260156 COLO741 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.14146078840301368 [223] [419,302,237] 3 hSpCas9 negative selection 5997072
166054712 166054735 2 - 27260156 COLO741 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.1041810966709183 [330] [408,425,518] 2 hSpCas9 negative selection 5997073
166048914 166048937 2 + 27260156 CAL120 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.088252996063237 [23] [45,14,25] -1 hSpCas9 negative selection 6054068
166051889 166051912 2 - 27260156 CAL120 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.37985545617492755 [370] [511,810,467] 6 hSpCas9 negative selection 6054069
166051971 166051994 2 - 27260156 CAL120 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.06671900294623687 [460] [544,461,633] -1 hSpCas9 negative selection 6054070
166048932 166048955 2 - 27260156 CAL120 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.19785634537797456 [628] [816,444,802] -3 hSpCas9 negative selection 6118322
166054653 166054676 2 + 27260156 CAL120 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.19752749096746824 [223] [382,169,197] -3 hSpCas9 negative selection 6118323
166054712 166054735 2 - 27260156 CAL120 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.32939577951471916 [330] [690,509,379] 5 hSpCas9 negative selection 6118324
166048914 166048937 2 + 27260156 CADOES1 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 1.1274349322731232 [23] [77,55,37,21] 9 hSpCas9 negative selection 6175319
166051889 166051912 2 - 27260156 CADOES1 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.453726096137705 [370] [447,551,456,431] 7 hSpCas9 negative selection 6175320
166051971 166051994 2 - 27260156 CADOES1 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.04258257596472299 [460] [441,422,309,492] 0 hSpCas9 negative selection 6175321
166048932 166048955 2 - 27260156 CADOES1 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.26628341644547493 [628] [489,549,489,412] -4 hSpCas9 negative selection 6239573
166054653 166054676 2 + 27260156 CADOES1 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.02407413523803137 [223] [180,213,209,214] 0 hSpCas9 negative selection 6239574
166054712 166054735 2 - 27260156 CADOES1 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.41510193838980053 [330] [465,395,388,389] 7 hSpCas9 negative selection 6239575
166048914 166048937 2 + 27260156 EWS502 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.22563679820934723 [23] [7,23,28,27] -4 hSpCas9 negative selection 6296570
166051889 166051912 2 - 27260156 EWS502 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.2350504213937671 [370] [480,432,393,543] 4 hSpCas9 negative selection 6296571
166051971 166051994 2 - 27260156 EWS502 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.07949025478090854 [460] [529,458,492,584] 1 hSpCas9 negative selection 6296572
166048932 166048955 2 - 27260156 EWS502 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.15952104906375647 [628] [558,522,678,633] -3 hSpCas9 negative selection 6360824
166054653 166054676 2 + 27260156 EWS502 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.0989731715583334 [223] [142,416,345,106] 1 hSpCas9 negative selection 6360825
166054712 166054735 2 - 27260156 EWS502 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.20045438751864064 [330] [395,472,444,285] 3 hSpCas9 negative selection 6360826
166048914 166048937 2 + 27260156 EW8 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.313604039166707 [23] [17,51,18,7] 6 hSpCas9 negative selection 6417821
166051889 166051912 2 - 27260156 EW8 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.03507659076984315 [370] [291,322,281,336] 0 hSpCas9 negative selection 6417822
166051971 166051994 2 - 27260156 EW8 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.23876631845856747 [460] [514,341,432,480] 4 hSpCas9 negative selection 6417823
166048932 166048955 2 - 27260156 EW8 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.01292559025965978 [628] [476,458,479,603] 0 hSpCas9 negative selection 6482075
166054653 166054676 2 + 27260156 EW8 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.07308671095895858 [223] [184,160,202,136] -1 hSpCas9 negative selection 6482076
166054712 166054735 2 - 27260156 EW8 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.06459477318108936 [330] [279,172,240,432] 1 hSpCas9 negative selection 6482077
166048914 166048937 2 + 27260156 CORL105 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.9700559850394073 [23] [30,62,91,38] 9 hSpCas9 negative selection 6539072
166051889 166051912 2 - 27260156 CORL105 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 -0.012052447463848592 [370] [359,358,498,513] 0 hSpCas9 negative selection 6539073
166051971 166051994 2 - 27260156 CORL105 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.23541839208137855 [460] [616,540,810,600] 4 hSpCas9 negative selection 6539074
166048932 166048955 2 - 27260156 CORL105 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.1482650729725981 [628] [515,487,935,757] -3 hSpCas9 negative selection 6603326
166054653 166054676 2 + 27260156 CORL105 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.012778659281236449 [223] [255,224,367,225] 0 hSpCas9 negative selection 6603327
166054712 166054735 2 - 27260156 CORL105 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.32133709753744943 [330] [542,490,429,465] 6 hSpCas9 negative selection 6603328
166048914 166048937 2 + 27260156 HS294T viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 1.0369002521882664 [23] [39,0,12,20] 9 hSpCas9 negative selection 6660323
166051889 166051912 2 - 27260156 HS294T viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 -0.4710569496845361 [370] [94,103,108,106] -6 hSpCas9 negative selection 6660324
166051971 166051994 2 - 27260156 HS294T viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.09187701239634687 [460] [156,202,146,267] 1 hSpCas9 negative selection 6660325
166048932 166048955 2 - 27260156 HS294T viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.02681680840646783 [628] [235,206,230,289] 0 hSpCas9 negative selection 6724577
166054653 166054676 2 + 27260156 HS294T viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.24978532192009983 [223] [183,54,59,106] 3 hSpCas9 negative selection 6724578
166054712 166054735 2 - 27260156 HS294T viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.08034178459312907 [330] [169,159,78,125] 1 hSpCas9 negative selection 6724579
166048914 166048937 2 + 27260156 HCC44 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.6212057400653235 [23] [59,8,24,74] 8 hSpCas9 negative selection 6781574
166051889 166051912 2 - 27260156 HCC44 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.2981496672639712 [370] [493,451,652,491] 5 hSpCas9 negative selection 6781575
166051971 166051994 2 - 27260156 HCC44 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.03088522594512403 [460] [495,483,623,456] 0 hSpCas9 negative selection 6781576
166048932 166048955 2 - 27260156 HCC44 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 0.21513687455809544 [628] [923,759,1194,509] 3 hSpCas9 negative selection 6845828
166054653 166054676 2 + 27260156 HCC44 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.05410635298402444 [223] [227,252,282,214] -1 hSpCas9 negative selection 6845829
166054712 166054735 2 - 27260156 HCC44 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.2783425571608928 [330] [375,463,398,551] 4 hSpCas9 negative selection 6845830
166048914 166048937 2 + 27260156 G402 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.14645502286774903 [23] [57,35,14,2] -2 hSpCas9 negative selection 6902825
166051889 166051912 2 - 27260156 G402 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.14340302455220746 [370] [356,749,279,599] 1 hSpCas9 negative selection 6902826
166051971 166051994 2 - 27260156 G402 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.29458937926273154 [460] [1247,790,653,175] 3 hSpCas9 negative selection 6902827
166048932 166048955 2 - 27260156 G402 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 0.07731090887619768 [628] [1129,817,1062,296] 1 hSpCas9 negative selection 6967079
166054653 166054676 2 + 27260156 G402 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.460062506727434 [223] [550,104,144,45] -5 hSpCas9 negative selection 6967080
166054712 166054735 2 - 27260156 G402 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.5932448648592862 [330] [658,429,888,460] 7 hSpCas9 negative selection 6967081
166048914 166048937 2 + 27260156 L33 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.588034078634903 [23] [26,20,11,46] 9 hSpCas9 negative selection 7024076
166051889 166051912 2 - 27260156 L33 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.10941505193821746 [370] [393,166,310,305] 2 hSpCas9 negative selection 7024077
166051971 166051994 2 - 27260156 L33 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.4827716974345013 [460] [664,286,385,596] 8 hSpCas9 negative selection 7024078
166048932 166048955 2 - 27260156 L33 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 0.16993022454167067 [628] [863,270,411,645] 4 hSpCas9 negative selection 7088330
166054653 166054676 2 + 27260156 L33 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.15060813659275474 [223] [251,105,158,230] 3 hSpCas9 negative selection 7088331
166054712 166054735 2 - 27260156 L33 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.09231913392763508 [330] [340,126,244,370] 2 hSpCas9 negative selection 7088332
166048914 166048937 2 + 27260156 K562 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 1.0568973752640827 [23] [146,12,18,8] 9 hSpCas9 negative selection 7145327
166051889 166051912 2 - 27260156 K562 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.03552759500072067 [370] [410,453,162,332] 0 hSpCas9 negative selection 7145328
166051971 166051994 2 - 27260156 K562 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.48381360534194107 [460] [143,291,109,576] -5 hSpCas9 negative selection 7145329
166048932 166048955 2 - 27260156 K562 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.0768016045488833 [628] [394,335,770,584] -1 hSpCas9 negative selection 7209581
166054653 166054676 2 + 27260156 K562 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.0870536332408256 [223] [160,194,424,73] 1 hSpCas9 negative selection 7209582
166054712 166054735 2 - 27260156 K562 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.2157710220556897 [330] [417,501,146,313] 2 hSpCas9 negative selection 7209583
166048914 166048937 2 + 27260156 HT29 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.5512196565740983 [23] [50,63,40,19] 9 hSpCas9 negative selection 7266578
166051889 166051912 2 - 27260156 HT29 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.1358002402171084 [370] [527,471,609,382] 2 hSpCas9 negative selection 7266579
166051971 166051994 2 - 27260156 HT29 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.17365125838315332 [460] [657,799,529,560] 3 hSpCas9 negative selection 7266580
166048932 166048955 2 - 27260156 HT29 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.11494810464689126 [628] [713,639,950,530] -2 hSpCas9 negative selection 7330832
166054653 166054676 2 + 27260156 HT29 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.2515165251540943 [223] [245,516,344,210] 5 hSpCas9 negative selection 7330833
166054712 166054735 2 - 27260156 HT29 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.28159506224518305 [330] [531,623,495,334] 5 hSpCas9 negative selection 7330834
166048914 166048937 2 + 27260156 MHHES1 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.08619382360574335 [23] [1,50,60,4] 1 hSpCas9 negative selection 7387829
166051889 166051912 2 - 27260156 MHHES1 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.11408286576948595 [370] [616,531,441,276] 2 hSpCas9 negative selection 7387830
166051971 166051994 2 - 27260156 MHHES1 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.05292447243132084 [460] [716,445,565,446] 1 hSpCas9 negative selection 7387831
166048932 166048955 2 - 27260156 MHHES1 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.21065694456922984 [628] [670,660,411,683] -4 hSpCas9 negative selection 7452083
166054653 166054676 2 + 27260156 MHHES1 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.520597121285846 [223] [120,229,215,139] -7 hSpCas9 negative selection 7452084
166054712 166054735 2 - 27260156 MHHES1 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.30116452005076505 [330] [392,478,520,433] 5 hSpCas9 negative selection 7452085
166048914 166048937 2 + 27260156 MEWO viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.5672196897793831 [23] [54,34,13] 9 hSpCas9 negative selection 7509080
166051889 166051912 2 - 27260156 MEWO viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 -0.1438822384963669 [370] [428,236,298] -3 hSpCas9 negative selection 7509081
166051971 166051994 2 - 27260156 MEWO viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.04270697444659006 [460] [584,428,345] 1 hSpCas9 negative selection 7509082
166048932 166048955 2 - 27260156 MEWO viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.4020417861819899 [628] [509,334,503] -7 hSpCas9 negative selection 7573334
166054653 166054676 2 + 27260156 MEWO viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.25847390440097917 [223] [171,157,194] -5 hSpCas9 negative selection 7573335
166054712 166054735 2 - 27260156 MEWO viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 -0.06430083050893953 [330] [350,310,236] -1 hSpCas9 negative selection 7573336
166048914 166048937 2 + 27260156 LNCAPCLONEFGC viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.005330814191129463 [23] [10,43,25,4] 0 hSpCas9 negative selection 7630331
166051889 166051912 2 - 27260156 LNCAPCLONEFGC viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.5171442080487979 [370] [384,415,745,421] 7 hSpCas9 negative selection 7630332
166051971 166051994 2 - 27260156 LNCAPCLONEFGC viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.0964194221651276 [460] [438,484,458,401] 1 hSpCas9 negative selection 7630333
166048932 166048955 2 - 27260156 LNCAPCLONEFGC viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.05492414430100484 [628] [394,501,799,539] -1 hSpCas9 negative selection 7694585
166054653 166054676 2 + 27260156 LNCAPCLONEFGC viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.17094922908483468 [223] [196,232,282,208] 2 hSpCas9 negative selection 7694586
166054712 166054735 2 - 27260156 LNCAPCLONEFGC viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.049869072364919054 [330] [319,309,342,272] 0 hSpCas9 negative selection 7694587
166048914 166048937 2 + 27260156 PANC0327 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.7352612839132173 [23] [30,70,25,8] 9 hSpCas9 negative selection 7751582
166051889 166051912 2 - 27260156 PANC0327 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.6255473003824541 [370] [574,363,646,471] 8 hSpCas9 negative selection 7751583
166051971 166051994 2 - 27260156 PANC0327 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.10266726247648267 [460] [573,229,552,439] 1 hSpCas9 negative selection 7751584
166048932 166048955 2 - 27260156 PANC0327 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.09337873297164212 [628] [674,518,586,326] -1 hSpCas9 negative selection 7815836
166054653 166054676 2 + 27260156 PANC0327 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.10885138892154345 [223] [146,209,112,382] 1 hSpCas9 negative selection 7815837
166054712 166054735 2 - 27260156 PANC0327 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 -0.09339409506392582 [330] [204,280,365,243] -1 hSpCas9 negative selection 7815838
166048914 166048937 2 + 27260156 NCIH2009 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 1.1449449670228682 [23] [139,37,57] 9 hSpCas9 negative selection 7872833
166051889 166051912 2 - 27260156 NCIH2009 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.414347832807067 [370] [619,647,789] 6 hSpCas9 negative selection 7872834
166051971 166051994 2 - 27260156 NCIH2009 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.04548665791179922 [460] [762,551,584] 0 hSpCas9 negative selection 7872835
166048932 166048955 2 - 27260156 NCIH2009 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.3445072690095715 [628] [874,546,691] -4 hSpCas9 negative selection 7937087
166054653 166054676 2 + 27260156 NCIH2009 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.15286026173117406 [223] [459,187,232] -2 hSpCas9 negative selection 7937088
166054712 166054735 2 - 27260156 NCIH2009 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.45956918575247263 [330] [561,587,742] 6 hSpCas9 negative selection 7937089
166048914 166048937 2 + 27260156 NCIH1373 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 0.5616149402169435 [23] [70,8,79,0] 5 hSpCas9 negative selection 7994084
166051889 166051912 2 - 27260156 NCIH1373 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.9702711774828561 [370] [1651,647,460,167] 8 hSpCas9 negative selection 7994085
166051971 166051994 2 - 27260156 NCIH1373 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.15421229127620542 [460] [455,320,571,136] -1 hSpCas9 negative selection 7994086
166048932 166048955 2 - 27260156 NCIH1373 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 0.32757564920742094 [628] [878,805,817,275] 3 hSpCas9 negative selection 8058338
166054653 166054676 2 + 27260156 NCIH1373 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.5020144643684625 [223] [174,154,165,56] -5 hSpCas9 negative selection 8058339
166054712 166054735 2 - 27260156 NCIH1373 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.6917731491645167 [330] [994,570,437,117] 7 hSpCas9 negative selection 8058340
166048914 166048937 2 + 27260156 PATU8902 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.19538993632835577 [23] [16,74,1,29] -2 hSpCas9 negative selection 8115335
166051889 166051912 2 - 27260156 PATU8902 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.7672088802910901 [370] [890,718,1050,793] 7 hSpCas9 negative selection 8115336
166051971 166051994 2 - 27260156 PATU8902 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 -0.37326534073729145 [460] [406,456,364,823] -4 hSpCas9 negative selection 8115337
166048932 166048955 2 - 27260156 PATU8902 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.04229504795546618 [628] [1136,735,678,888] 0 hSpCas9 negative selection 8179589
166054653 166054676 2 + 27260156 PATU8902 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 -0.07422254258289507 [223] [572,214,74,383] 0 hSpCas9 negative selection 8179590
166054712 166054735 2 - 27260156 PATU8902 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.4427460204289385 [330] [588,456,307,1311] 4 hSpCas9 negative selection 8179591
166048914 166048937 2 + 27260156 PANC1 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.35531376408739845 [23] [7,24,28,5] -5 hSpCas9 negative selection 8236586
166051889 166051912 2 - 27260156 PANC1 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.32867855601897006 [370] [351,430,361,447] 5 hSpCas9 negative selection 8236587
166051971 166051994 2 - 27260156 PANC1 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.23175146216883702 [460] [408,325,711,391] 3 hSpCas9 negative selection 8236588
166048932 166048955 2 - 27260156 PANC1 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.09492047292658018 [628] [651,583,403,403] -1 hSpCas9 negative selection 8300840
166054653 166054676 2 + 27260156 PANC1 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.3104886765058186 [223] [281,196,191,264] 5 hSpCas9 negative selection 8300841
166054712 166054735 2 - 27260156 PANC1 viability CACTTATAAAAATTATTGCAAGG SCN1A ENSG00000144285 0.2647189297876793 [330] [355,404,437,198] 4 hSpCas9 negative selection 8300842
166048914 166048937 2 + 27260156 PANC0813 viability GTGCATCTAAAAAACCCTCCAGG SCN1A ENSG00000144285 -0.021526169021997887 [23] [41,21,31,16] 0 hSpCas9 negative selection 8357837
166051889 166051912 2 - 27260156 PANC0813 viability CTGAGCGTATTTGCTCTAATTGG SCN1A ENSG00000144285 0.11261412695617987 [370] [468,618,376,420] 1 hSpCas9 negative selection 8357838
166051971 166051994 2 - 27260156 PANC0813 viability TTCAGGCCTGAAAACCATTGTGG SCN1A ENSG00000144285 0.11132225988310637 [460] [503,527,817,487] 1 hSpCas9 negative selection 8357839
166048932 166048955 2 - 27260156 PANC0813 viability AACAGGATATCATTATTTCCTGG SCN1A ENSG00000144285 -0.18206932664263004 [628] [713,643,797,464] -3 hSpCas9 negative selection 8422091
166054653 166054676 2 + 27260156 PANC0813 viability GTGAAATCGAGCCAGTTCCATGG SCN1A ENSG00000144285 0.06354797608551976 [223] [199,334,359,201] 1 hSpCas9 negative selection 8422092