Crispr
Gene Info
- Species: Human
(Homo sapiens)
- GeneID: 79583
- Symbol: TMEM231
- Description: transmembrane protein 231
DataSource:
http://genomecrispr.dkfz.de/#!/results/TMEM231
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| Start |
The end |
chr |
strand |
pubmed |
cellline |
condition |
sequence |
symbol |
ensg |
log2fc |
rc_initial |
rc_final |
effect |
cas |
screentype |
index |
75540024 |
75540047 |
16 |
- |
26627737 |
DLD1 |
viability |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
-0.0393354554880343 |
[703] |
[302,165,176] |
0 |
hSpCas9 |
negative selection |
795429 |
75540163 |
75540186 |
16 |
- |
26627737 |
DLD1 |
viability |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.8961331566151489 |
[242] |
[45,237,143] |
8 |
hSpCas9 |
negative selection |
795430 |
75540024 |
75540047 |
16 |
- |
26627737 |
GBM cells |
viability after 5 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.3239354627371515 |
[215] |
[169,119] |
5 |
hSpCas9 |
negative selection |
877744 |
75540163 |
75540186 |
16 |
- |
26627737 |
GBM cells |
viability after 5 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
-0.13856083053297713 |
[194] |
[104,84] |
-2 |
hSpCas9 |
negative selection |
877745 |
75540024 |
75540047 |
16 |
- |
26627737 |
GBM cells |
viability after 13 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.08909085191657244 |
[215] |
[138,112] |
1 |
hSpCas9 |
negative selection |
960059 |
75540163 |
75540186 |
16 |
- |
26627737 |
GBM cells |
viability after 13 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
-0.21045513008043848 |
[194] |
[75,103] |
-3 |
hSpCas9 |
negative selection |
960060 |
75540024 |
75540047 |
16 |
- |
26627737 |
GBM cells |
viability after 21 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
-0.46224901607696667 |
[215] |
[80,88] |
-4 |
hSpCas9 |
negative selection |
1042374 |
75540163 |
75540186 |
16 |
- |
26627737 |
GBM cells |
viability after 21 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
-0.09418257464115343 |
[194] |
[116,82] |
-1 |
hSpCas9 |
negative selection |
1042375 |
75540024 |
75540047 |
16 |
- |
26627737 |
RPE1 |
viability after 9 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
1.18317262001908 |
[328] |
[208,265] |
7 |
hSpCas9 |
negative selection |
1124689 |
75540163 |
75540186 |
16 |
- |
26627737 |
RPE1 |
viability after 9 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.9998269922776001 |
[403] |
[186,337] |
6 |
hSpCas9 |
negative selection |
1124690 |
75540024 |
75540047 |
16 |
- |
26627737 |
RPE1 |
viability after 12 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.800418756455233 |
[328] |
[151,155] |
5 |
hSpCas9 |
negative selection |
1207004 |
75540163 |
75540186 |
16 |
- |
26627737 |
RPE1 |
viability after 12 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
1.00513853420135 |
[403] |
[144,294] |
6 |
hSpCas9 |
negative selection |
1207005 |
75540024 |
75540047 |
16 |
- |
26627737 |
RPE1 |
viability after 15 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.42048851310587454 |
[328] |
[64,181] |
2 |
hSpCas9 |
negative selection |
1289319 |
75540163 |
75540186 |
16 |
- |
26627737 |
RPE1 |
viability after 15 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
1.5619425528022695 |
[403] |
[369,305] |
8 |
hSpCas9 |
negative selection |
1289320 |
75540024 |
75540047 |
16 |
- |
26627737 |
RPE1 |
viability after 18 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.7803675008800819 |
[328] |
[166,136] |
5 |
hSpCas9 |
negative selection |
1371634 |
75540163 |
75540186 |
16 |
- |
26627737 |
RPE1 |
viability after 18 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.9339659590121832 |
[403] |
[216,198] |
5 |
hSpCas9 |
negative selection |
1371635 |
75540024 |
75540047 |
16 |
- |
26627737 |
HeLa |
viability after 8 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.06064681052496185 |
[374] |
[129,205,165] |
0 |
hSpCas9 |
negative selection |
1453949 |
75540163 |
75540186 |
16 |
- |
26627737 |
HeLa |
viability after 8 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.7770004259578378 |
[314] |
[296,270,155] |
6 |
hSpCas9 |
negative selection |
1453950 |
75540024 |
75540047 |
16 |
- |
26627737 |
HeLa |
viability after 12 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.7852334582488353 |
[374] |
[462,105,254] |
6 |
hSpCas9 |
negative selection |
1536264 |
75540163 |
75540186 |
16 |
- |
26627737 |
HeLa |
viability after 12 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.806520300932378 |
[314] |
[456,139,101] |
6 |
hSpCas9 |
negative selection |
1536265 |
75540024 |
75540047 |
16 |
- |
26627737 |
HeLa |
viability after 15 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.12346852520108978 |
[374] |
[175,165,155] |
1 |
hSpCas9 |
negative selection |
1618579 |
75540163 |
75540186 |
16 |
- |
26627737 |
HeLa |
viability after 15 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.6904782855079645 |
[314] |
[191,270,153] |
5 |
hSpCas9 |
negative selection |
1618580 |
75540024 |
75540047 |
16 |
- |
26627737 |
HeLa |
viability after 18 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.16803091953303484 |
[374] |
[122,143,155] |
1 |
hSpCas9 |
negative selection |
1700894 |
75540163 |
75540186 |
16 |
- |
26627737 |
HeLa |
viability after 18 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.645555047178562 |
[314] |
[119,219,153] |
5 |
hSpCas9 |
negative selection |
1700895 |
75540024 |
75540047 |
16 |
- |
26627737 |
HCT116 |
viability after 6 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.3275029601065781 |
[1068] |
[527,35] |
1 |
hSpCas9 |
negative selection |
1783209 |
75540163 |
75540186 |
16 |
- |
26627737 |
HCT116 |
viability after 6 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
-1.6293718980611542 |
[689] |
[65,17] |
-7 |
hSpCas9 |
negative selection |
1783210 |
75540024 |
75540047 |
16 |
- |
26627737 |
HCT116 |
viability after 8 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.37319998686537625 |
[250] |
[244,147,145] |
4 |
hSpCas9 |
negative selection |
1865524 |
75540163 |
75540186 |
16 |
- |
26627737 |
HCT116 |
viability after 8 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.6741139935169719 |
[229] |
[228,163,213] |
6 |
hSpCas9 |
negative selection |
1865525 |
75540024 |
75540047 |
16 |
- |
26627737 |
HCT116 |
viability after 9 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
-0.2540701852144195 |
[1068] |
[359,143] |
-2 |
hSpCas9 |
negative selection |
1947839 |
75540163 |
75540186 |
16 |
- |
26627737 |
HCT116 |
viability after 9 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
-1.3154825552356344 |
[689] |
[130,28] |
-7 |
hSpCas9 |
negative selection |
1947840 |
75540024 |
75540047 |
16 |
- |
26627737 |
HCT116 |
viability after 12 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.5503617438442472 |
[250] |
[220,148,205] |
5 |
hSpCas9 |
negative selection |
2030154 |
75540163 |
75540186 |
16 |
- |
26627737 |
HCT116 |
viability after 12 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.47356336511413555 |
[229] |
[179,149,171] |
4 |
hSpCas9 |
negative selection |
2030155 |
75540024 |
75540047 |
16 |
- |
26627737 |
HCT116 |
viability after 15 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.1299941785112608 |
[250] |
[170,159,143] |
1 |
hSpCas9 |
negative selection |
2112469 |
75540163 |
75540186 |
16 |
- |
26627737 |
HCT116 |
viability after 15 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.6337067354259585 |
[229] |
[197,212,202] |
6 |
hSpCas9 |
negative selection |
2112470 |
75540024 |
75540047 |
16 |
- |
26627737 |
HCT116 |
viability after 18 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.07174339937517246 |
[250] |
[139,118,123] |
0 |
hSpCas9 |
negative selection |
2194784 |
75540163 |
75540186 |
16 |
- |
26627737 |
HCT116 |
viability after 18 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.40671017546069593 |
[229] |
[239,76,128] |
3 |
hSpCas9 |
negative selection |
2194785 |
75540024 |
75540047 |
16 |
- |
27869803 |
HPAFII |
viability after 27 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
-0.16703725652105514 |
[231] |
[82,129,NaN] |
-1 |
hSpCas9 |
negative selection |
9558447 |
75540163 |
75540186 |
16 |
- |
27869803 |
HPAFII |
viability after 27 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
1.455709587775692 |
[181] |
[418,131,NaN] |
9 |
hSpCas9 |
negative selection |
9558448 |
75540024 |
75540047 |
16 |
- |
27869803 |
HPAFII |
viability after 15 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
-0.11510274744368026 |
[231] |
[236,225,NaN] |
-1 |
hSpCas9 |
negative selection |
9640896 |
75540163 |
75540186 |
16 |
- |
27869803 |
HPAFII |
viability after 15 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
0.34117293151673633 |
[181] |
[433,131,NaN] |
4 |
hSpCas9 |
negative selection |
9640897 |
75540024 |
75540047 |
16 |
- |
27869803 |
ASPC1 |
viability after 36 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
-0.6233748514635834 |
[578] |
[376,74,1] |
-6 |
hSpCas9 |
negative selection |
9723345 |
75540163 |
75540186 |
16 |
- |
27869803 |
ASPC1 |
viability after 36 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
1.0576284899380142 |
[443] |
[733,78,223] |
8 |
hSpCas9 |
negative selection |
9723346 |
75540024 |
75540047 |
16 |
- |
27869803 |
PATU8988S |
viability after 35 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.25813912097547953 |
[470] |
[166,286,NaN] |
3 |
hSpCas9 |
negative selection |
9805794 |
75540163 |
75540186 |
16 |
- |
27869803 |
PATU8988S |
viability after 35 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
-0.6440761999527967 |
[501] |
[74,183,NaN] |
-6 |
hSpCas9 |
negative selection |
9805795 |
75540024 |
75540047 |
16 |
- |
27869803 |
PATU8988S |
viability after 31 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.39969451103515286 |
[470] |
[256,235,NaN] |
5 |
hSpCas9 |
negative selection |
9888243 |
75540163 |
75540186 |
16 |
- |
27869803 |
PATU8988S |
viability after 31 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
-0.9996180681295417 |
[501] |
[56,154,NaN] |
-7 |
hSpCas9 |
negative selection |
9888244 |
75540024 |
75540047 |
16 |
- |
27869803 |
HPAFII |
viability after 35 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.9487456233467384 |
[231] |
[213,240,NaN] |
6 |
hSpCas9 |
negative selection |
9970692 |
75540163 |
75540186 |
16 |
- |
27869803 |
HPAFII |
viability after 35 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
1.1741852236488968 |
[181] |
[285,119,NaN] |
7 |
hSpCas9 |
negative selection |
9970693 |
75540024 |
75540047 |
16 |
- |
27869803 |
HPAFII |
viability after 31 days |
TTCCTGTGACAGTGACGCCCCGG |
TMEM231 |
ENSG00000205084 |
0.8047505217354899 |
[231] |
[214,240,NaN] |
6 |
hSpCas9 |
negative selection |
10053141 |
75540163 |
75540186 |
16 |
- |
27869803 |
HPAFII |
viability after 31 days |
ACTGTCCATACTTATCAGCCAGG |
TMEM231 |
ENSG00000205084 |
1.4773542142086145 |
[181] |
[404,152,NaN] |
9 |
hSpCas9 |
negative selection |
10053142 |