Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 110876
  • Symbol: Scn2a
  • Description: sodium channel, voltage-gated, type II, alpha

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
110876 GO:0005248 IDA enables voltage-gated sodium channel activity 10827969 Function
110876 GO:0005248 IMP enables voltage-gated sodium channel activity 10827969 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
110876 GO:0005886 IDA located_in plasma membrane 10827969 Component
110876 GO:0014704 IDA located_in intercalated disc 15746173 Component
110876 GO:0016020 IDA located_in membrane 10827969,17537961 Component
110876 GO:0030315 IDA located_in T-tubule 15746173 Component
110876 GO:0030424 IDA located_in axon 17928448 Component
110876 GO:0033270 IDA located_in paranode region of axon 16723544 Component
110876 GO:0042734 IDA is_active_in presynaptic membrane 22528969 Component
110876 GO:0098978 IDA is_active_in glutamatergic synapse 22528969 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
110876 GO:0006814 IDA acts_upstream_of_or_within sodium ion transport 10827969 Process
110876 GO:0007399 IMP acts_upstream_of_or_within nervous system development 10827969 Process
110876 GO:0007613 IMP involved_in memory 29867081 Process
110876 GO:0008340 IGI acts_upstream_of_or_within determination of adult lifespan 21156207 Process
110876 GO:0008627 IMP acts_upstream_of_or_within intrinsic apoptotic signaling pathway in response to osmotic stress 10827969 Process
110876 GO:0021542 IGI acts_upstream_of_or_within dentate gyrus development 16464983 Process
110876 GO:0021675 IGI acts_upstream_of_or_within nerve development 16464983,21156207 Process
110876 GO:0021675 IMP acts_upstream_of_or_within nerve development 21156207 Process
110876 GO:0035725 IMP involved_in sodium ion transmembrane transport 10827969 Process
110876 GO:0051402 IMP acts_upstream_of_or_within neuron apoptotic process 10827969 Process