Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 177017
  • Symbol: vha-11
  • Description: V-type proton ATPase subunit C
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Gene ID Entry Entry Name Protein Name Type Information
177017 Q9XXU9 VATC_CAEEL V-type proton ATPase subunit C (V-ATPase subunit C) (Vacuolar proton pump subunit C) DISRUPTION PHENOTYPE Worms display embryonic lethality. When vha-11 is silenced in adults, they are able to produce eggs but egg numbers gradually decrease and worms become sterile after 24 hours. This sterility continues for about 4 days and then viable eggs are produced again. {ECO:0000269|PubMed:10846178}.