| 149142094 | 149142117 | | - | 24336571 | A375 | resistance to PLX after 7 days | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | -0.14894563610741773 | [35,26] | [29,26] | -5 | hSpCas9 | positive selection | 3130957 | 149142094 | 149142117 | | - | 24336571 | A375 | resistance to PLX after 14 days | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.13941609456945536 | [28,32] | [14,16] | 1 | hSpCas9 | positive selection | 3188750 | 149142094 | 149142117 | | - | 24336571 | A375 | viability after 7 days | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.8148461305856666 | [18] | [35,26] | 9 | hSpCas9 | negative selection | 3246543 | 149142094 | 149142117 | | - | 24336571 | A375 | viability after 14 days | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.8123929610916417 | [18] | [28,32] | 8 | hSpCas9 | negative selection | 3304336 | 149142094 | 149142117 | 5 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 8.287639899629081 | [297,355] | [0,1333] | 9 | hSpCas9 | positive selection | 3335135 | 149142094 | 149142117 | 5 | - | 26780180 | A375 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.793004691843811 | [] | [] | 3 | hSpCas9 | negative selection | 3910266 | 149142094 | 149142117 | 5 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.142664445093012 | [] | [] | 0 | hSpCas9 | negative selection | 4018232 | 149142094 | 149142117 | 5 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.38509785942559316 | [4] | [3,3] | 8 | hSpCas9 | positive selection | 4155632 | 149142094 | 149142117 | 5 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.8024077454027002 | [4] | [3,3,1,3] | 5 | hSpCas9 | positive selection | 4219654 | 149142094 | 149142117 | 5 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.44707375303289854 | [3] | [4,3] | 8 | hSpCas9 | positive selection | 4254020 | 149141919 | 149141942 | 5 | + | 27661255 | K562 | viability | GGCTACAGCCCAGACAGAGAGGG | ABLIM3 | ENSG00000173210 | 0.21425780598941224 | [262,224] | [290,171] | 7 | dCas9-KRAB | negative selection | 5460311 | 149141519 | 149141542 | 5 | - | 27661255 | K562 | viability | GGAGCTCGACATCCATGATGCGG | ABLIM3 | ENSG00000173210 | -0.34551508400401154 | [367,384] | [249,224] | -7 | dCas9-KRAB | negative selection | 5460312 | 149141540 | 149141563 | 5 | - | 27661255 | K562 | viability | GGGCTAGCAATGCGAAATAGGGG | ABLIM3 | ENSG00000173210 | 0.0070119615028294 | [614,538] | [541,397] | 0 | dCas9-KRAB | negative selection | 5460313 | 149141560 | 149141583 | 5 | - | 27661255 | K562 | viability | GTCTGGGGTCTCGAATTCCAGGG | ABLIM3 | ENSG00000173210 | 0.16968457945378068 | [1594,2008] | [1836,1420] | 6 | dCas9-KRAB | negative selection | 5460314 | 149142094 | 149142117 | 5 | - | 27260156 | BXPC3 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.2782707883457677 | [797] | [849,1010,1008,1212] | 6 | hSpCas9 | negative selection | 5526480 | 149142094 | 149142117 | 5 | - | 27260156 | A673 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.2711156087878065 | [797] | [1268,1000,1188,1181] | 6 | hSpCas9 | negative selection | 5647731 | 149142094 | 149142117 | 5 | - | 27260156 | A375 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.23155031218177569 | [797] | [941,1219,1027,1187] | 3 | hSpCas9 | negative selection | 5768982 | 149142094 | 149142117 | 5 | - | 27260156 | COLO741 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.1400239325159598 | [797] | [1132,1183,1056] | 3 | hSpCas9 | negative selection | 5890233 | 149142094 | 149142117 | 5 | - | 27260156 | CAL120 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.5806674570119567 | [797] | [2037,1300,1203] | 8 | hSpCas9 | negative selection | 6011484 | 149142094 | 149142117 | 5 | - | 27260156 | CADOES1 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.43411444930776744 | [797] | [1047,908,1195,851] | 7 | hSpCas9 | negative selection | 6132735 | 149142094 | 149142117 | 5 | - | 27260156 | EWS502 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.27699423021973246 | [797] | [791,1127,781,1440] | 5 | hSpCas9 | negative selection | 6253986 | 149142094 | 149142117 | 5 | - | 27260156 | EW8 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.39917871634354773 | [797] | [1115,708,885,720] | 7 | hSpCas9 | negative selection | 6375237 | 149142094 | 149142117 | 5 | - | 27260156 | CORL105 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.4332958327327229 | [797] | [1511,1032,1438,1102] | 7 | hSpCas9 | negative selection | 6496488 | 149142094 | 149142117 | 5 | - | 27260156 | HS294T | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.28825549134134676 | [797] | [374,330,377,432] | 4 | hSpCas9 | negative selection | 6617739 | 149142094 | 149142117 | 5 | - | 27260156 | HCC44 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.3410371760270413 | [797] | [1203,1148,1401,866] | 5 | hSpCas9 | negative selection | 6738990 | 149142094 | 149142117 | 5 | - | 27260156 | G402 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.32782278052807967 | [797] | [1141,1047,1002,1647] | 4 | hSpCas9 | negative selection | 6860241 | 149142094 | 149142117 | 5 | - | 27260156 | L33 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.29843943521330074 | [797] | [988,356,687,970] | 6 | hSpCas9 | negative selection | 6981492 | 149142094 | 149142117 | 5 | - | 27260156 | K562 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.23406826196655917 | [797] | [585,791,1172,762] | 3 | hSpCas9 | negative selection | 7102743 | 149142094 | 149142117 | 5 | - | 27260156 | HT29 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.40686710041838314 | [797] | [1475,1465,1106,1134] | 7 | hSpCas9 | negative selection | 7223994 | 149142094 | 149142117 | 5 | - | 27260156 | MHHES1 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.2251399367267185 | [797] | [1368,988,1005,884] | 4 | hSpCas9 | negative selection | 7345245 | 149142094 | 149142117 | 5 | - | 27260156 | MEWO | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.3403783966135979 | [797] | [993,727,1123] | 7 | hSpCas9 | negative selection | 7466496 | 149142094 | 149142117 | 5 | - | 27260156 | LNCAPCLONEFGC | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.5020657386515547 | [797] | [1081,1039,1251,751] | 7 | hSpCas9 | negative selection | 7587747 | 149142094 | 149142117 | 5 | - | 27260156 | PANC0327 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.633728129342029 | [797] | [1114,636,1198,1508] | 8 | hSpCas9 | negative selection | 7708998 | 149142094 | 149142117 | 5 | - | 27260156 | NCIH2009 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.3568608924289344 | [797] | [1850,1134,1383] | 5 | hSpCas9 | negative selection | 7830249 | 149142094 | 149142117 | 5 | - | 27260156 | NCIH1373 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.4357246236163631 | [797] | [989,1273,1370,301] | 4 | hSpCas9 | negative selection | 7951500 | 149142094 | 149142117 | 5 | - | 27260156 | PATU8902 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.5314011442582277 | [797] | [1729,1498,1988,1022] | 5 | hSpCas9 | negative selection | 8072751 | 149142094 | 149142117 | 5 | - | 27260156 | PANC1 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.30088554081585206 | [797] | [695,924,1085,701] | 5 | hSpCas9 | negative selection | 8194002 | 149142094 | 149142117 | 5 | - | 27260156 | PANC0813 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.4696009625968375 | [797] | [1274,1462,1238,1214] | 7 | hSpCas9 | negative selection | 8315253 | 149142094 | 149142117 | 5 | - | 27260156 | RDES | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.4750981149420227 | [797] | [1060,938,1599,1606] | 7 | hSpCas9 | negative selection | 8436504 | 149142094 | 149142117 | 5 | - | 27260156 | PC3 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.27322486206906993 | [797] | [585,1059,1582,922] | 6 | hSpCas9 | negative selection | 8557755 | 149142094 | 149142117 | 5 | - | 27260156 | PATU8988T | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.27303094882198786 | [797] | [914,1326,697,817] | 5 | hSpCas9 | negative selection | 8679006 | 149142094 | 149142117 | 5 | - | 27260156 | T47D | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.15674074711492147 | [797] | [1100,906,1078,1069] | 3 | hSpCas9 | negative selection | 8800257 | 149142094 | 149142117 | 5 | - | 27260156 | SU8686 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.49413134734011954 | [797] | [932,1038,1161,1391] | 8 | hSpCas9 | negative selection | 8921508 | 149142094 | 149142117 | 5 | - | 27260156 | SKES1 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.30566900451616996 | [797] | [1240,1215,891,677] | 6 | hSpCas9 | negative selection | 9042759 | 149142094 | 149142117 | 5 | - | 27260156 | TOV112D | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.09527849445770531 | [797] | [861,793,970,774] | 1 | hSpCas9 | negative selection | 9164010 | 149142094 | 149142117 | 5 | - | 27260156 | TC71 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.23246778144707492 | [797] | [981,1028,937,1077] | 6 | hSpCas9 | negative selection | 9285261 | 149142094 | 149142117 | 5 | - | 27260156 | TC32 | viability | CCACTTACTGCTAGTGTTCATGG | ABLIM3 | ENSG00000173210 | 0.4414731943981872 | [797] | [1022,737,1371,1047] | 7 | hSpCas9 | negative selection | 9406512 |