Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:59
• Symbol:ACTA2
• Description:actin alpha 2, smooth muscle

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTA2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
88948823	88948846	10	+	26472758	Jiyoye	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	-0.10852445677816908	[182]	[127]	-1	hSpCas9	negative selection	2002
88938171	88938194	10	-	26472758	Jiyoye	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	-0.19967972506412504	[165]	[108]	-1	hSpCas9	negative selection	2003
88943838	88943861	10	-	26472758	Jiyoye	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.43518975767546975	[50]	[51]	3	hSpCas9	negative selection	2004
88941221	88941244	10	+	26472758	Jiyoye	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.43235394450187026	[283]	[288]	3	hSpCas9	negative selection	2005
88939604	88939627	10	+	26472758	Jiyoye	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-0.778380271650203	[115]	[50]	-5	hSpCas9	negative selection	2006
88939522	88939545	10	+	26472758	Jiyoye	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	0.622564415104559	[117]	[136]	4	hSpCas9	negative selection	2007
88948883	88948906	10	+	26472758	Jiyoye	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.5296593880308684	[78]	[85]	4	hSpCas9	negative selection	2008
88948855	88948878	10	-	26472758	Jiyoye	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-0.5244376435138763	[102]	[53]	-4	hSpCas9	negative selection	2009
88943877	88943900	10	+	26472758	Jiyoye	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.6409725661145707	[107]	[126]	5	hSpCas9	negative selection	2010
88939541	88939564	10	+	26472758	Jiyoye	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.22917707952787875	[111]	[98]	1	hSpCas9	negative selection	2011
88948823	88948846	10	+	26472758	KBM7	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	0.08059072248788429	[769,399]	[341,229]	0	hSpCas9	negative selection	193120
88938171	88938194	10	-	26472758	KBM7	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.10377584061280998	[652,686]	[292,383]	1	hSpCas9	negative selection	193121
88943838	88943861	10	-	26472758	KBM7	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.22899990652177682	[289,185]	[206,58]	2	hSpCas9	negative selection	193122
88941221	88941244	10	+	26472758	KBM7	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.283680879323998	[943,1006]	[630,501]	3	hSpCas9	negative selection	193123
88939604	88939627	10	+	26472758	KBM7	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-2.6525229777946877	[434,263]	[32,18]	-9	hSpCas9	negative selection	193124
88939522	88939545	10	+	26472758	KBM7	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.6609087258163361	[776,479]	[205,162]	-5	hSpCas9	negative selection	193125
88948883	88948906	10	+	26472758	KBM7	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.21973270259045707	[378,377]	[180,128]	-2	hSpCas9	negative selection	193126
88948855	88948878	10	-	26472758	KBM7	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-0.4911846961166021	[356,181]	[132,46]	-4	hSpCas9	negative selection	193127
88943877	88943900	10	+	26472758	KBM7	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.41936463174946775	[599,404]	[268,348]	4	hSpCas9	negative selection	193128
88939541	88939564	10	+	26472758	KBM7	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.083565820741336	[366,467]	[362,476]	9	hSpCas9	negative selection	193129
88948823	88948846	10	+	26472758	Raji	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	0.9929841626365131	[222]	[102]	8	hSpCas9	negative selection	384238
88938171	88938194	10	-	26472758	Raji	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.03261576697162716	[395]	[93]	0	hSpCas9	negative selection	384239
88943838	88943861	10	-	26472758	Raji	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	1.5983698878857415	[36]	[25]	9	hSpCas9	negative selection	384240
88941221	88941244	10	+	26472758	Raji	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.12274784502577885	[466]	[117]	1	hSpCas9	negative selection	384241
88939604	88939627	10	+	26472758	Raji	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-0.037006373961575245	[167]	[37]	0	hSpCas9	negative selection	384242
88939522	88939545	10	+	26472758	Raji	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.927381882787077	[335]	[40]	-6	hSpCas9	negative selection	384243
88948883	88948906	10	+	26472758	Raji	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.3336593911972755	[211]	[61]	3	hSpCas9	negative selection	384244
88948855	88948878	10	-	26472758	Raji	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	0.9009326579061732	[89]	[38]	7	hSpCas9	negative selection	384245
88943877	88943900	10	+	26472758	Raji	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	-0.18874855863642526	[387]	[78]	-1	hSpCas9	negative selection	384246
88939541	88939564	10	+	26472758	Raji	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.7082124415537767	[210]	[79]	6	hSpCas9	negative selection	384247
88948823	88948846	10	+	26472758	K562	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	-0.286095989032333	[363]	[251]	-2	hSpCas9	negative selection	575356
88938171	88938194	10	-	26472758	K562	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	1.082857199158761	[386]	[691]	8	hSpCas9	negative selection	575357
88943838	88943861	10	-	26472758	K562	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-0.597516426101302	[189]	[105]	-4	hSpCas9	negative selection	575358
88941221	88941244	10	+	26472758	K562	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.042935296092979636	[958]	[833]	0	hSpCas9	negative selection	575359
88939604	88939627	10	+	26472758	K562	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-4.3751899158616006	[294]	[11]	-9	hSpCas9	negative selection	575360
88939522	88939545	10	+	26472758	K562	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-2.5577090327276077	[550]	[78]	-8	hSpCas9	negative selection	575361
88948883	88948906	10	+	26472758	K562	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.9684452661251549	[223]	[369]	7	hSpCas9	negative selection	575362
88948855	88948878	10	-	26472758	K562	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-0.07340107291867026	[262]	[210]	0	hSpCas9	negative selection	575363
88943877	88943900	10	+	26472758	K562	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.2680484740513466	[544]	[553]	2	hSpCas9	negative selection	575364
88939541	88939564	10	+	26472758	K562	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.474792884664369	[308]	[724]	9	hSpCas9	negative selection	575365
88935253	88935276	10	-	26627737	DLD1	viability	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	-0.35787331311016957	[300]	[63,148,18]	-4	hSpCas9	negative selection	776002
88938140	88938163	10	-	26627737	DLD1	viability	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	1.3739006634837008	[144]	[205,28,113]	9	hSpCas9	negative selection	776003
88939497	88939520	10	+	26627737	DLD1	viability	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.7774835802870662	[430]	[324,129,232]	7	hSpCas9	negative selection	776004
88939541	88939564	10	+	26627737	DLD1	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.2840808209361461	[372]	[213,74,134]	3	hSpCas9	negative selection	776005
88941221	88941244	10	+	26627737	DLD1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.7231110868168482	[302]	[120,229,125]	7	hSpCas9	negative selection	776006
88941780	88941803	10	+	26627737	DLD1	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.5004754347154143	[639]	[435,198,219]	5	hSpCas9	negative selection	776007
88935253	88935276	10	-	26627737	GBM cells	viability after 5 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	0.6815570434465361	[142]	[142,102]	8	hSpCas9	negative selection	858317
88938140	88938163	10	-	26627737	GBM cells	viability after 5 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.8975527310291824	[197]	[49,63]	-8	hSpCas9	negative selection	858318
88939497	88939520	10	+	26627737	GBM cells	viability after 5 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.3939694032537044	[319]	[226,223]	6	hSpCas9	negative selection	858319
88939541	88939564	10	+	26627737	GBM cells	viability after 5 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.7368571167767128	[79]	[165,119]	9	hSpCas9	negative selection	858320
88941221	88941244	10	+	26627737	GBM cells	viability after 5 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.06884578811410658	[176]	[94,85]	-1	hSpCas9	negative selection	858321
88941780	88941803	10	+	26627737	GBM cells	viability after 5 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.1893726575322694	[218]	[96,108]	-3	hSpCas9	negative selection	858322
88935253	88935276	10	-	26627737	GBM cells	viability after 13 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	0.337158105526054	[142]	[54,132]	4	hSpCas9	negative selection	940632
88938140	88938163	10	-	26627737	GBM cells	viability after 13 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.8000892985541537	[197]	[80,45]	-7	hSpCas9	negative selection	940633
88939497	88939520	10	+	26627737	GBM cells	viability after 13 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.11063890495666723	[319]	[219,160]	1	hSpCas9	negative selection	940634
88939541	88939564	10	+	26627737	GBM cells	viability after 13 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.335446392919617	[79]	[151,74]	9	hSpCas9	negative selection	940635
88941221	88941244	10	+	26627737	GBM cells	viability after 13 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.026607185532379507	[176]	[88,104]	0	hSpCas9	negative selection	940636
88941780	88941803	10	+	26627737	GBM cells	viability after 13 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.46913085867341586	[218]	[244,98]	6	hSpCas9	negative selection	940637
88935253	88935276	10	-	26627737	GBM cells	viability after 21 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	1.4243424164631815	[142]	[219,197]	9	hSpCas9	negative selection	1022947
88938140	88938163	10	-	26627737	GBM cells	viability after 21 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.6506232858156082	[197]	[67,68]	-5	hSpCas9	negative selection	1022948
88939497	88939520	10	+	26627737	GBM cells	viability after 21 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.5141810957939754	[319]	[264,232]	5	hSpCas9	negative selection	1022949
88939541	88939564	10	+	26627737	GBM cells	viability after 21 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.6327440384064942	[79]	[139,129]	9	hSpCas9	negative selection	1022950
88941221	88941244	10	+	26627737	GBM cells	viability after 21 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.07957761026864274	[176]	[90,90]	0	hSpCas9	negative selection	1022951
88941780	88941803	10	+	26627737	GBM cells	viability after 21 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.5548241939878594	[218]	[179,169]	5	hSpCas9	negative selection	1022952
88935253	88935276	10	-	26627737	RPE1	viability after 9 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	5.224982659918651	[17]	[308,83]	9	hSpCas9	negative selection	1105262
88938140	88938163	10	-	26627737	RPE1	viability after 9 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-4.079162647348723	[437]	[1,15]	-9	hSpCas9	negative selection	1105263
88939497	88939520	10	+	26627737	RPE1	viability after 9 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	1.5393783855765362	[473]	[443,414]	8	hSpCas9	negative selection	1105264
88939541	88939564	10	+	26627737	RPE1	viability after 9 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.8485059098028225	[861]	[574,370]	5	hSpCas9	negative selection	1105265
88941221	88941244	10	+	26627737	RPE1	viability after 9 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.7947848870708435	[592]	[82,137]	-5	hSpCas9	negative selection	1105266
88941780	88941803	10	+	26627737	RPE1	viability after 9 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-1.0517269678502983	[1437]	[83,388]	-6	hSpCas9	negative selection	1105267
88935253	88935276	10	-	26627737	RPE1	viability after 12 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	5.20838933652678	[17]	[324,23]	9	hSpCas9	negative selection	1187577
88938140	88938163	10	-	26627737	RPE1	viability after 12 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-2.459136756414251	[437]	[0,42]	-9	hSpCas9	negative selection	1187578
88939497	88939520	10	+	26627737	RPE1	viability after 12 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	1.9429120990107869	[473]	[561,412]	8	hSpCas9	negative selection	1187579
88939541	88939564	10	+	26627737	RPE1	viability after 12 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.7040810166935285	[861]	[369,384]	4	hSpCas9	negative selection	1187580
88941221	88941244	10	+	26627737	RPE1	viability after 12 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.46028543977099134	[592]	[57,176]	-3	hSpCas9	negative selection	1187581
88941780	88941803	10	+	26627737	RPE1	viability after 12 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.5192127632233188	[1437]	[84,464]	-4	hSpCas9	negative selection	1187582
88935253	88935276	10	-	26627737	RPE1	viability after 15 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	4.783785557021209	[17]	[209,72]	9	hSpCas9	negative selection	1269892
88938140	88938163	10	-	26627737	RPE1	viability after 15 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-2.457128910289817	[437]	[18,25]	-8	hSpCas9	negative selection	1269893
88939497	88939520	10	+	26627737	RPE1	viability after 15 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	1.8763093816542136	[473]	[673,316]	8	hSpCas9	negative selection	1269894
88939541	88939564	10	+	26627737	RPE1	viability after 15 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.0088863116645514	[861]	[535,446]	6	hSpCas9	negative selection	1269895
88941221	88941244	10	+	26627737	RPE1	viability after 15 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.48131890705863667	[592]	[82,155]	-3	hSpCas9	negative selection	1269896
88941780	88941803	10	+	26627737	RPE1	viability after 15 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.366344276419461	[1437]	[227,399]	-2	hSpCas9	negative selection	1269897
88935253	88935276	10	-	26627737	RPE1	viability after 18 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	5.146127265709437	[17]	[288,46]	9	hSpCas9	negative selection	1352207
88938140	88938163	10	-	26627737	RPE1	viability after 18 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-2.502930179795594	[437]	[1,40]	-8	hSpCas9	negative selection	1352208
88939497	88939520	10	+	26627737	RPE1	viability after 18 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	1.7969569288787315	[473]	[458,428]	8	hSpCas9	negative selection	1352209
88939541	88939564	10	+	26627737	RPE1	viability after 18 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.0875706210577323	[861]	[475,513]	6	hSpCas9	negative selection	1352210
88941221	88941244	10	+	26627737	RPE1	viability after 18 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.5804974663009613	[592]	[92,121]	-4	hSpCas9	negative selection	1352211
88941780	88941803	10	+	26627737	RPE1	viability after 18 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-1.2646411739325398	[1437]	[59,269]	-7	hSpCas9	negative selection	1352212
88935253	88935276	10	-	26627737	HeLa	viability after 8 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	0.5013392780307548	[259]	[265,125,114]	4	hSpCas9	negative selection	1434522
88938140	88938163	10	-	26627737	HeLa	viability after 8 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.43813282711938895	[218]	[79,45,85]	-4	hSpCas9	negative selection	1434523
88939497	88939520	10	+	26627737	HeLa	viability after 8 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	-0.3176240203029962	[718]	[319,355,102]	-3	hSpCas9	negative selection	1434524
88939541	88939564	10	+	26627737	HeLa	viability after 8 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	-0.4460911492625783	[485]	[242,145,99]	-4	hSpCas9	negative selection	1434525
88941221	88941244	10	+	26627737	HeLa	viability after 8 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.18583778051993274	[297]	[115,148,168]	1	hSpCas9	negative selection	1434526
88941780	88941803	10	+	26627737	HeLa	viability after 8 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.06231737360501921	[201]	[161,54,74]	0	hSpCas9	negative selection	1434527
88935253	88935276	10	-	26627737	HeLa	viability after 12 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	0.5118839843408218	[259]	[219,186,50]	4	hSpCas9	negative selection	1516837
88938140	88938163	10	-	26627737	HeLa	viability after 12 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-3.436522479251167	[218]	[7,8,7]	-9	hSpCas9	negative selection	1516838
88939497	88939520	10	+	26627737	HeLa	viability after 12 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	-0.4835514003650886	[718]	[333,184,124]	-4	hSpCas9	negative selection	1516839
88939541	88939564	10	+	26627737	HeLa	viability after 12 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	-0.018430342540172506	[485]	[150,155,290]	0	hSpCas9	negative selection	1516840
88941221	88941244	10	+	26627737	HeLa	viability after 12 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.5675830695385113	[297]	[313,119,123]	5	hSpCas9	negative selection	1516841
88941780	88941803	10	+	26627737	HeLa	viability after 12 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.25432949087461953	[201]	[5,108,179]	2	hSpCas9	negative selection	1516842
88935253	88935276	10	-	26627737	HeLa	viability after 15 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	-0.44020182208038183	[259]	[73,58,102]	-4	hSpCas9	negative selection	1599152
88938140	88938163	10	-	26627737	HeLa	viability after 15 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.45567531216856416	[218]	[73,78,39]	-4	hSpCas9	negative selection	1599153
88939497	88939520	10	+	26627737	HeLa	viability after 15 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.03174530214728499	[718]	[337,285,270]	0	hSpCas9	negative selection	1599154
88939541	88939564	10	+	26627737	HeLa	viability after 15 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.12518050659828933	[485]	[98,259,295]	1	hSpCas9	negative selection	1599155
88941221	88941244	10	+	26627737	HeLa	viability after 15 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.44036157232895634	[297]	[108,56,102]	-4	hSpCas9	negative selection	1599156
88941780	88941803	10	+	26627737	HeLa	viability after 15 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.3174892695236714	[201]	[114,80,111]	2	hSpCas9	negative selection	1599157
88935253	88935276	10	-	26627737	HeLa	viability after 18 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	-0.3800051393358609	[259]	[55,48,102]	-3	hSpCas9	negative selection	1681467
88938140	88938163	10	-	26627737	HeLa	viability after 18 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.441855062862881	[218]	[47,68,39]	-4	hSpCas9	negative selection	1681468
88939497	88939520	10	+	26627737	HeLa	viability after 18 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.04791653589719358	[718]	[229,240,270]	0	hSpCas9	negative selection	1681469
88939541	88939564	10	+	26627737	HeLa	viability after 18 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.09932599715442614	[485]	[59,213,295]	0	hSpCas9	negative selection	1681470
88941221	88941244	10	+	26627737	HeLa	viability after 18 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.43121082339374783	[297]	[71,49,102]	-4	hSpCas9	negative selection	1681471
88941780	88941803	10	+	26627737	HeLa	viability after 18 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.33176794886967587	[201]	[79,65,111]	2	hSpCas9	negative selection	1681472
88935253	88935276	10	-	26627737	HCT116	viability after 6 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	-2.9983655182503024	[383]	[13,3]	-9	hSpCas9	negative selection	1763782
88938140	88938163	10	-	26627737	HCT116	viability after 6 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.353309477647851	[435]	[130,10]	-2	hSpCas9	negative selection	1763783
88939497	88939520	10	+	26627737	HCT116	viability after 6 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	-2.247278915367521	[1180]	[80,15]	-8	hSpCas9	negative selection	1763784
88939541	88939564	10	+	26627737	HCT116	viability after 6 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.689664009450094	[374]	[97,240]	8	hSpCas9	negative selection	1763785
88941221	88941244	10	+	26627737	HCT116	viability after 6 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.014390670916826272	[611]	[24,133]	0	hSpCas9	negative selection	1763786
88941780	88941803	10	+	26627737	HCT116	viability after 6 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	1.519283495310016	[682]	[689,96]	7	hSpCas9	negative selection	1763787
88935253	88935276	10	-	26627737	HCT116	viability after 8 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	1.3691107970275562	[68]	[69,114,108]	9	hSpCas9	negative selection	1846097
88938140	88938163	10	-	26627737	HCT116	viability after 8 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	1.0154256483342385	[48]	[71,32,58]	8	hSpCas9	negative selection	1846098
88939497	88939520	10	+	26627737	HCT116	viability after 8 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	-0.10621693302360136	[503]	[229,242,299]	-1	hSpCas9	negative selection	1846099
88939541	88939564	10	+	26627737	HCT116	viability after 8 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.45221324241928634	[245]	[148,244,161]	5	hSpCas9	negative selection	1846100
88941221	88941244	10	+	26627737	HCT116	viability after 8 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.7568279976399566	[383]	[64,135,172]	-7	hSpCas9	negative selection	1846101
88941780	88941803	10	+	26627737	HCT116	viability after 8 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.3625760526956914	[226]	[148,233,99]	4	hSpCas9	negative selection	1846102
88935253	88935276	10	-	26627737	HCT116	viability after 9 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	0.11268572148321465	[383]	[135,90]	0	hSpCas9	negative selection	1928412
88938140	88938163	10	-	26627737	HCT116	viability after 9 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-4.12428064746773	[435]	[4,7]	-9	hSpCas9	negative selection	1928413
88939497	88939520	10	+	26627737	HCT116	viability after 9 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	-0.32249235515394514	[1180]	[321,196]	-2	hSpCas9	negative selection	1928414
88939541	88939564	10	+	26627737	HCT116	viability after 9 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.3186749627284399	[374]	[187,74]	2	hSpCas9	negative selection	1928415
88941221	88941244	10	+	26627737	HCT116	viability after 9 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.37068934214410754	[611]	[136,117]	-3	hSpCas9	negative selection	1928416
88941780	88941803	10	+	26627737	HCT116	viability after 9 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.06926039731045186	[682]	[106,257]	0	hSpCas9	negative selection	1928417
88935253	88935276	10	-	26627737	HCT116	viability after 12 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	1.2424525653006966	[68]	[73,150,34]	8	hSpCas9	negative selection	2010727
88938140	88938163	10	-	26627737	HCT116	viability after 12 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	1.5615240893705915	[48]	[36,139,55]	9	hSpCas9	negative selection	2010728
88939497	88939520	10	+	26627737	HCT116	viability after 12 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	-0.4406099532442646	[503]	[152,228,207]	-5	hSpCas9	negative selection	2010729
88939541	88939564	10	+	26627737	HCT116	viability after 12 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.07870035215979096	[245]	[25,206,187]	0	hSpCas9	negative selection	2010730
88941221	88941244	10	+	26627737	HCT116	viability after 12 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.5925317061974407	[383]	[142,187,70]	-6	hSpCas9	negative selection	2010731
88941780	88941803	10	+	26627737	HCT116	viability after 12 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.455680224000741	[226]	[120,181,191]	4	hSpCas9	negative selection	2010732
88935253	88935276	10	-	26627737	HCT116	viability after 15 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	1.8956883453747104	[68]	[123,209,105]	9	hSpCas9	negative selection	2093042
88938140	88938163	10	-	26627737	HCT116	viability after 15 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	1.6284541378606834	[48]	[48,170,36]	9	hSpCas9	negative selection	2093043
88939497	88939520	10	+	26627737	HCT116	viability after 15 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	-0.5266237679447728	[503]	[220,164,218]	-5	hSpCas9	negative selection	2093044
88939541	88939564	10	+	26627737	HCT116	viability after 15 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.6445849438473977	[245]	[120,273,254]	6	hSpCas9	negative selection	2093045
88941221	88941244	10	+	26627737	HCT116	viability after 15 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.1575132502774265	[383]	[223,227,144]	-2	hSpCas9	negative selection	2093046
88941780	88941803	10	+	26627737	HCT116	viability after 15 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.5423633163338162	[226]	[155,181,226]	5	hSpCas9	negative selection	2093047
88935253	88935276	10	-	26627737	HCT116	viability after 18 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	1.835230780052083	[68]	[49,190,110]	9	hSpCas9	negative selection	2175357
88938140	88938163	10	-	26627737	HCT116	viability after 18 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	1.1683508704535392	[48]	[91,34,32]	8	hSpCas9	negative selection	2175358
88939497	88939520	10	+	26627737	HCT116	viability after 18 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.35034139245003193	[503]	[347,302,279]	3	hSpCas9	negative selection	2175359
88939541	88939564	10	+	26627737	HCT116	viability after 18 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.277820410588936	[245]	[91,118,226]	2	hSpCas9	negative selection	2175360
88941221	88941244	10	+	26627737	HCT116	viability after 18 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.14390550239401292	[383]	[159,188,152]	-1	hSpCas9	negative selection	2175361
88941780	88941803	10	+	26627737	HCT116	viability after 18 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.3034415228057741	[226]	[0,98,316]	2	hSpCas9	negative selection	2175362
88973914	88973937	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTCAGCCTCCCGAGTAGCGAG	ACTA2	ENSG00000107796	0.5805591546882161	[16,8]	[5,1]	2	dCas9-VP64	positive selection	2421397
88952955	88952978	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGTTTCATGAGCAGACCAGTGG	ACTA2	ENSG00000107796	0.8304256042666058	[328,329]	[53,209]	3	dCas9-VP64	positive selection	2428177
88952990	88953013	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGTGTTTATCTCCCACAGGCGG	ACTA2	ENSG00000107796	0.6787383792143782	[31,49]	[8,19]	3	dCas9-VP64	positive selection	2428178
88952910	88952933	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCTAATCTGGGTGGCCGGAGG	ACTA2	ENSG00000107796	-2.867778375392392	[249,120]	[4,4]	-9	dCas9-VP64	positive selection	2428179
88990380	88990403	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACAGCAGAAGCCTTTAGAAAGG	ACTA2	ENSG00000107796	0.9533400867264815	[141,73]	[21,70]	4	dCas9-VP64	positive selection	2467801
88990425	88990448	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCATGCTCACTTCAGGTGAGG	ACTA2	ENSG00000107796	-0.1661811422518059	[21,242]	[11,40]	0	dCas9-VP64	positive selection	2467802
88990356	88990379	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAACCTGGGAAGTTGGGGAGG	ACTA2	ENSG00000107796	-0.8532801869636175	[228,171]	[43,2]	-5	dCas9-VP64	positive selection	2467803
88973914	88973937	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTCAGCCTCCCGAGTAGCGAG	ACTA2	ENSG00000107796	0.21208715000527545	[37,95]	[24,24]	1	dCas9-VP64	positive selection	2516652
88952955	88952978	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGTTTCATGAGCAGACCAGTGG	ACTA2	ENSG00000107796	-0.13313181986794387	[206,406]	[115,66]	-1	dCas9-VP64	positive selection	2523432
88952990	88953013	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGTGTTTATCTCCCACAGGCGG	ACTA2	ENSG00000107796	0.44717845927611977	[43,96]	[41,19]	3	dCas9-VP64	positive selection	2523433
88952910	88952933	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCTAATCTGGGTGGCCGGAGG	ACTA2	ENSG00000107796	-0.05300376469020196	[41,47]	[13,13]	0	dCas9-VP64	positive selection	2523434
88990380	88990403	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACAGCAGAAGCCTTTAGAAAGG	ACTA2	ENSG00000107796	0.3694462660097122	[191,50]	[54,48]	3	dCas9-VP64	positive selection	2563056
88990425	88990448	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCATGCTCACTTCAGGTGAGG	ACTA2	ENSG00000107796	1.5979962806035102	[110,22]	[118,18]	8	dCas9-VP64	positive selection	2563057
88990356	88990379	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAACCTGGGAAGTTGGGGAGG	ACTA2	ENSG00000107796	1.3334156617524056	[23,73]	[15,61]	7	dCas9-VP64	positive selection	2563058
88943838	88943861	10	-	27260157	DLD1	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.429458580096975	[]	[]	7	hSpCas9	negative selection	2574120
88948900	88948923	10	-	27260157	DLD1	viability	AGAAGAGGACAGCACTGCCTTGG	ACTA2	ENSG00000107796	0.563246064928116	[]	[]	8	hSpCas9	negative selection	2575481
88947290	88947313	10	+	27260157	DLD1	viability	CATGTTCTATCGGGTACTTCAGG	ACTA2	ENSG00000107796	0.155482978320339	[]	[]	3	hSpCas9	negative selection	2576245
88941366	88941389	10	-	27260157	DLD1	viability	ATCGTGCTGGACTCTGGAGATGG	ACTA2	ENSG00000107796	-0.102115553112339	[]	[]	0	hSpCas9	negative selection	2577287
88948928	88948951	10	+	27260157	DLD1	viability	CATAGCTGGAGCTGCTTCACAGG	ACTA2	ENSG00000107796	-0.529801840439689	[]	[]	-4	hSpCas9	negative selection	2582361
88943833	88943856	10	+	27260157	DLD1	viability	GGGTGCCTCCGTGAGCAGGGTGG	ACTA2	ENSG00000107796	-0.955960519188488	[]	[]	-7	hSpCas9	negative selection	2582408
88941819	88941842	10	+	27260157	DLD1	viability	CGCCTGGATAGCCACATACATGG	ACTA2	ENSG00000107796	-0.0683239383033899	[]	[]	0	hSpCas9	negative selection	2583062
88941818	88941841	10	-	27260157	DLD1	viability	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.217610939293946	[]	[]	3	hSpCas9	negative selection	2584995
88948915	88948938	10	-	27260157	DLD1	viability	TCCAGCTATGTGTGAAGAAGAGG	ACTA2	ENSG00000107796	-1.06613467837587	[]	[]	-7	hSpCas9	negative selection	2606637
88941379	88941402	10	-	27260157	DLD1	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.536675379201171	[]	[]	-4	hSpCas9	negative selection	2608710
88941830	88941853	10	-	27260157	DLD1	viability	CAATGTCCCAGCCATGTATGTGG	ACTA2	ENSG00000107796	0.237506663241755	[]	[]	4	hSpCas9	negative selection	2609396
88947289	88947312	10	-	27260157	DLD1	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.0266932218055346	[]	[]	0	hSpCas9	negative selection	2613690
88948855	88948878	10	-	27260157	DLD1	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-1.15131180158771	[]	[]	-7	hSpCas9	negative selection	2613959
88941803	88941826	10	+	27260157	DLD1	viability	CATAGAGAGACAGCACCGCCTGG	ACTA2	ENSG00000107796	-1.18809815709271	[]	[]	-7	hSpCas9	negative selection	2615068
88948866	88948889	10	-	27260157	DLD1	viability	GGCTCTGGGCTCTGTAAGGCCGG	ACTA2	ENSG00000107796	-0.208697716746881	[]	[]	-1	hSpCas9	negative selection	2624329
88948805	88948828	10	+	27260157	DLD1	viability	ATGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.404333640961155	[]	[]	4	hSpCas9	negative selection	2640787
88948914	88948937	10	+	27260157	DLD1	viability	TCCTCTTCTTCACACATAGCTGG	ACTA2	ENSG00000107796	-0.720748038437761	[]	[]	-5	hSpCas9	negative selection	2643949
88941780	88941803	10	+	27260157	DLD1	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.190123298647017	[]	[]	-1	hSpCas9	negative selection	2647509
88943838	88943861	10	-	27260157	HT1080	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.276354044506228	[]	[]	2	hSpCas9	negative selection	2650250
88948900	88948923	10	-	27260157	HT1080	viability	AGAAGAGGACAGCACTGCCTTGG	ACTA2	ENSG00000107796	1.26884049958959	[]	[]	8	hSpCas9	negative selection	2651611
88947290	88947313	10	+	27260157	HT1080	viability	CATGTTCTATCGGGTACTTCAGG	ACTA2	ENSG00000107796	-0.518570701285823	[]	[]	-7	hSpCas9	negative selection	2652375
88941366	88941389	10	-	27260157	HT1080	viability	ATCGTGCTGGACTCTGGAGATGG	ACTA2	ENSG00000107796	0.629889338970797	[]	[]	5	hSpCas9	negative selection	2653417
88948928	88948951	10	+	27260157	HT1080	viability	CATAGCTGGAGCTGCTTCACAGG	ACTA2	ENSG00000107796	-0.063479992287648	[]	[]	0	hSpCas9	negative selection	2658491
88943833	88943856	10	+	27260157	HT1080	viability	GGGTGCCTCCGTGAGCAGGGTGG	ACTA2	ENSG00000107796	-0.377940285356679	[]	[]	-7	hSpCas9	negative selection	2658538
88941819	88941842	10	+	27260157	HT1080	viability	CGCCTGGATAGCCACATACATGG	ACTA2	ENSG00000107796	-0.377284403702181	[]	[]	-7	hSpCas9	negative selection	2659192
88941818	88941841	10	-	27260157	HT1080	viability	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.00763151953333864	[]	[]	0	hSpCas9	negative selection	2661125
88948915	88948938	10	-	27260157	HT1080	viability	TCCAGCTATGTGTGAAGAAGAGG	ACTA2	ENSG00000107796	0.397802988130172	[]	[]	3	hSpCas9	negative selection	2682767
88941379	88941402	10	-	27260157	HT1080	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.144678406491924	[]	[]	0	hSpCas9	negative selection	2684840
88941830	88941853	10	-	27260157	HT1080	viability	CAATGTCCCAGCCATGTATGTGG	ACTA2	ENSG00000107796	0.155111301600085	[]	[]	1	hSpCas9	negative selection	2685526
88947289	88947312	10	-	27260157	HT1080	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.549789894106156	[]	[]	5	hSpCas9	negative selection	2689820
88948855	88948878	10	-	27260157	HT1080	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-1.05452188768883	[]	[]	-8	hSpCas9	negative selection	2690089
88941803	88941826	10	+	27260157	HT1080	viability	CATAGAGAGACAGCACCGCCTGG	ACTA2	ENSG00000107796	-1.02455599728175	[]	[]	-8	hSpCas9	negative selection	2691198
88948866	88948889	10	-	27260157	HT1080	viability	GGCTCTGGGCTCTGTAAGGCCGG	ACTA2	ENSG00000107796	-0.126850392738685	[]	[]	0	hSpCas9	negative selection	2700459
88948805	88948828	10	+	27260157	HT1080	viability	ATGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.046872301889168	[]	[]	0	hSpCas9	negative selection	2716917
88948914	88948937	10	+	27260157	HT1080	viability	TCCTCTTCTTCACACATAGCTGG	ACTA2	ENSG00000107796	-0.544190097578076	[]	[]	-7	hSpCas9	negative selection	2720079
88941780	88941803	10	+	27260157	HT1080	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.423834151263147	[]	[]	-7	hSpCas9	negative selection	2723639
88943838	88943861	10	-	27260157	MKN45	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.119326766816291	[]	[]	4	hSpCas9	negative selection	2726380
88948900	88948923	10	-	27260157	MKN45	viability	AGAAGAGGACAGCACTGCCTTGG	ACTA2	ENSG00000107796	1.73525175344204	[]	[]	9	hSpCas9	negative selection	2727741
88947290	88947313	10	+	27260157	MKN45	viability	CATGTTCTATCGGGTACTTCAGG	ACTA2	ENSG00000107796	-1.06728699502283	[]	[]	-8	hSpCas9	negative selection	2728505
88941366	88941389	10	-	27260157	MKN45	viability	ATCGTGCTGGACTCTGGAGATGG	ACTA2	ENSG00000107796	-0.795760596413461	[]	[]	-7	hSpCas9	negative selection	2729547
88948928	88948951	10	+	27260157	MKN45	viability	CATAGCTGGAGCTGCTTCACAGG	ACTA2	ENSG00000107796	-0.264929919444422	[]	[]	-1	hSpCas9	negative selection	2734621
88943833	88943856	10	+	27260157	MKN45	viability	GGGTGCCTCCGTGAGCAGGGTGG	ACTA2	ENSG00000107796	-0.767795598425876	[]	[]	-7	hSpCas9	negative selection	2734668
88941819	88941842	10	+	27260157	MKN45	viability	CGCCTGGATAGCCACATACATGG	ACTA2	ENSG00000107796	-0.38343945865946	[]	[]	-1	hSpCas9	negative selection	2735322
88941818	88941841	10	-	27260157	MKN45	viability	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.0565822550549541	[]	[]	0	hSpCas9	negative selection	2737255
88948915	88948938	10	-	27260157	MKN45	viability	TCCAGCTATGTGTGAAGAAGAGG	ACTA2	ENSG00000107796	-0.100445324428866	[]	[]	0	hSpCas9	negative selection	2758897
88941379	88941402	10	-	27260157	MKN45	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.738241186428667	[]	[]	-7	hSpCas9	negative selection	2760970
88941830	88941853	10	-	27260157	MKN45	viability	CAATGTCCCAGCCATGTATGTGG	ACTA2	ENSG00000107796	0.432378382648786	[]	[]	6	hSpCas9	negative selection	2761656
88947289	88947312	10	-	27260157	MKN45	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.170037563356971	[]	[]	0	hSpCas9	negative selection	2765950
88948855	88948878	10	-	27260157	MKN45	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-0.673027838022958	[]	[]	-7	hSpCas9	negative selection	2766219
88941803	88941826	10	+	27260157	MKN45	viability	CATAGAGAGACAGCACCGCCTGG	ACTA2	ENSG00000107796	-0.940752880186805	[]	[]	-7	hSpCas9	negative selection	2767328
88948866	88948889	10	-	27260157	MKN45	viability	GGCTCTGGGCTCTGTAAGGCCGG	ACTA2	ENSG00000107796	-0.712507376788791	[]	[]	-7	hSpCas9	negative selection	2776589
88948805	88948828	10	+	27260157	MKN45	viability	ATGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.591516554186993	[]	[]	7	hSpCas9	negative selection	2793047
88948914	88948937	10	+	27260157	MKN45	viability	TCCTCTTCTTCACACATAGCTGG	ACTA2	ENSG00000107796	-1.15030212553494	[]	[]	-8	hSpCas9	negative selection	2796209
88941780	88941803	10	+	27260157	MKN45	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-1.41809886310435	[]	[]	-8	hSpCas9	negative selection	2799769
88943838	88943861	10	-	27260157	RKO	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.777484949041585	[]	[]	8	hSpCas9	negative selection	2802510
88948900	88948923	10	-	27260157	RKO	viability	AGAAGAGGACAGCACTGCCTTGG	ACTA2	ENSG00000107796	1.48165888321904	[]	[]	9	hSpCas9	negative selection	2803871
88947290	88947313	10	+	27260157	RKO	viability	CATGTTCTATCGGGTACTTCAGG	ACTA2	ENSG00000107796	-0.319235469329043	[]	[]	-6	hSpCas9	negative selection	2804635
88941366	88941389	10	-	27260157	RKO	viability	ATCGTGCTGGACTCTGGAGATGG	ACTA2	ENSG00000107796	0.271610854934996	[]	[]	1	hSpCas9	negative selection	2805677
88948928	88948951	10	+	27260157	RKO	viability	CATAGCTGGAGCTGCTTCACAGG	ACTA2	ENSG00000107796	0.0337546531864723	[]	[]	0	hSpCas9	negative selection	2810751
88943833	88943856	10	+	27260157	RKO	viability	GGGTGCCTCCGTGAGCAGGGTGG	ACTA2	ENSG00000107796	-1.47822419895109	[]	[]	-8	hSpCas9	negative selection	2810798
88941819	88941842	10	+	27260157	RKO	viability	CGCCTGGATAGCCACATACATGG	ACTA2	ENSG00000107796	0.0918255519435343	[]	[]	0	hSpCas9	negative selection	2811452
88941818	88941841	10	-	27260157	RKO	viability	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.0786828882110638	[]	[]	0	hSpCas9	negative selection	2813385
88948915	88948938	10	-	27260157	RKO	viability	TCCAGCTATGTGTGAAGAAGAGG	ACTA2	ENSG00000107796	-0.654038252507369	[]	[]	-7	hSpCas9	negative selection	2835027
88941379	88941402	10	-	27260157	RKO	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.806594281684974	[]	[]	-7	hSpCas9	negative selection	2837100
88941830	88941853	10	-	27260157	RKO	viability	CAATGTCCCAGCCATGTATGTGG	ACTA2	ENSG00000107796	-0.342136440547213	[]	[]	-6	hSpCas9	negative selection	2837786
88947289	88947312	10	-	27260157	RKO	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.314222467174407	[]	[]	1	hSpCas9	negative selection	2842080
88948855	88948878	10	-	27260157	RKO	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-0.291512259064919	[]	[]	-6	hSpCas9	negative selection	2842349
88941803	88941826	10	+	27260157	RKO	viability	CATAGAGAGACAGCACCGCCTGG	ACTA2	ENSG00000107796	-0.218076072426131	[]	[]	-1	hSpCas9	negative selection	2843458
88948866	88948889	10	-	27260157	RKO	viability	GGCTCTGGGCTCTGTAAGGCCGG	ACTA2	ENSG00000107796	-0.592752761194701	[]	[]	-7	hSpCas9	negative selection	2852719
88948805	88948828	10	+	27260157	RKO	viability	ATGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.162029664674831	[]	[]	0	hSpCas9	negative selection	2869177
88948914	88948937	10	+	27260157	RKO	viability	TCCTCTTCTTCACACATAGCTGG	ACTA2	ENSG00000107796	-0.0879782872531646	[]	[]	0	hSpCas9	negative selection	2872339
88941780	88941803	10	+	27260157	RKO	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.327767641600416	[]	[]	-6	hSpCas9	negative selection	2875899
88943838	88943861	10	-	27260157	SF268	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	1.346468231379	[]	[]	9	hSpCas9	negative selection	2878640
88948900	88948923	10	-	27260157	SF268	viability	AGAAGAGGACAGCACTGCCTTGG	ACTA2	ENSG00000107796	1.72126491086217	[]	[]	9	hSpCas9	negative selection	2880001
88947290	88947313	10	+	27260157	SF268	viability	CATGTTCTATCGGGTACTTCAGG	ACTA2	ENSG00000107796	-1.49194784096051	[]	[]	-8	hSpCas9	negative selection	2880765
88941366	88941389	10	-	27260157	SF268	viability	ATCGTGCTGGACTCTGGAGATGG	ACTA2	ENSG00000107796	0.216877658238426	[]	[]	3	hSpCas9	negative selection	2881807
88948928	88948951	10	+	27260157	SF268	viability	CATAGCTGGAGCTGCTTCACAGG	ACTA2	ENSG00000107796	0.146658311496937	[]	[]	0	hSpCas9	negative selection	2886881
88943833	88943856	10	+	27260157	SF268	viability	GGGTGCCTCCGTGAGCAGGGTGG	ACTA2	ENSG00000107796	0.480008373247833	[]	[]	7	hSpCas9	negative selection	2886928
88941819	88941842	10	+	27260157	SF268	viability	CGCCTGGATAGCCACATACATGG	ACTA2	ENSG00000107796	0.450279643932112	[]	[]	7	hSpCas9	negative selection	2887582
88941818	88941841	10	-	27260157	SF268	viability	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	-0.0807280683347386	[]	[]	0	hSpCas9	negative selection	2889515
88948915	88948938	10	-	27260157	SF268	viability	TCCAGCTATGTGTGAAGAAGAGG	ACTA2	ENSG00000107796	0.0593968287941117	[]	[]	0	hSpCas9	negative selection	2911157
88941379	88941402	10	-	27260157	SF268	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-1.23902690110707	[]	[]	-7	hSpCas9	negative selection	2913230
88941830	88941853	10	-	27260157	SF268	viability	CAATGTCCCAGCCATGTATGTGG	ACTA2	ENSG00000107796	0.81011949875185	[]	[]	8	hSpCas9	negative selection	2913916
88947289	88947312	10	-	27260157	SF268	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.297079712659743	[]	[]	4	hSpCas9	negative selection	2918210
88948855	88948878	10	-	27260157	SF268	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	0.305301937287837	[]	[]	4	hSpCas9	negative selection	2918479
88941803	88941826	10	+	27260157	SF268	viability	CATAGAGAGACAGCACCGCCTGG	ACTA2	ENSG00000107796	-1.15172101710923	[]	[]	-7	hSpCas9	negative selection	2919588
88948866	88948889	10	-	27260157	SF268	viability	GGCTCTGGGCTCTGTAAGGCCGG	ACTA2	ENSG00000107796	0.0478073793023402	[]	[]	0	hSpCas9	negative selection	2928849
88948805	88948828	10	+	27260157	SF268	viability	ATGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.279030216111999	[]	[]	4	hSpCas9	negative selection	2945307
88948914	88948937	10	+	27260157	SF268	viability	TCCTCTTCTTCACACATAGCTGG	ACTA2	ENSG00000107796	0.299319591042048	[]	[]	4	hSpCas9	negative selection	2948469
88941780	88941803	10	+	27260157	SF268	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.0821327669667251	[]	[]	0	hSpCas9	negative selection	2952029
88948884	88948907	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.05510320497637691	[4,3]	[3,2]	-1	hSpCas9	positive selection	2968674
88941818	88941841	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.049578442463523	[4,4]	[3,3]	1	hSpCas9	positive selection	2968675
88947346	88947369	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACAAAAAGACAGCTACGTGGG	ACTA2	ENSG00000107796	0.41964876714063587	[4,3]	[5,4]	8	hSpCas9	positive selection	2968676
88947347	88947370	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.39728326921210705	[4,4]	[5,4]	8	hSpCas9	positive selection	2968677
88948884	88948907	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.05899710675292952	[4,4]	[4,1]	1	hSpCas9	positive selection	3036532
88941818	88941841	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	-0.7489141742338676	[4,4]	[2,0]	-8	hSpCas9	positive selection	3036533
88947346	88947369	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACAAAAAGACAGCTACGTGGG	ACTA2	ENSG00000107796	-0.09998573643613018	[4,4]	[2,2]	-1	hSpCas9	positive selection	3036534
88947347	88947370	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.10266005792057112	[4,4]	[3,1]	-1	hSpCas9	positive selection	3036535
88943877	88943900		+	24336571	A375	resistance to PLX after 7 days	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	-0.38894137336180723	[4,4]	[3,3]	-9	hSpCas9	positive selection	3159606
88947347	88947370		-	24336571	A375	resistance to PLX after 7 days	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	1.8663617622053144	[11,8]	[38,40]	9	hSpCas9	positive selection	3159616
88943829	88943852		+	24336571	A375	resistance to PLX after 7 days	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.298523693340385	[6,7]	[4,6]	-8	hSpCas9	positive selection	3159618
88943877	88943900		+	24336571	A375	resistance to PLX after 14 days	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.4514042590499896	[2,3]	[1,1]	4	hSpCas9	positive selection	3217399
88947347	88947370		-	24336571	A375	resistance to PLX after 14 days	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	10.65050401865117	[12,3]	[6206,7623]	9	hSpCas9	positive selection	3217409
88943829	88943852		+	24336571	A375	resistance to PLX after 14 days	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-1.2472032550286947	[10,12]	[1,1]	-9	hSpCas9	positive selection	3217411
88943877	88943900		+	24336571	A375	viability after 7 days	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	-0.22026601280135938	[5]	[4,4]	-3	hSpCas9	negative selection	3275192
88947347	88947370		-	24336571	A375	viability after 7 days	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	1.1287805221346905	[4]	[11,8]	9	hSpCas9	negative selection	3275202
88943829	88943852		+	24336571	A375	viability after 7 days	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	0.3459774327074181	[5]	[6,7]	5	hSpCas9	negative selection	3275204
88943877	88943900		+	24336571	A375	viability after 14 days	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	-0.7144865727261247	[5]	[2,3]	-7	hSpCas9	negative selection	3332985
88947347	88947370		-	24336571	A375	viability after 14 days	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.8698182500923745	[4]	[12,3]	9	hSpCas9	negative selection	3332995
88943829	88943852		+	24336571	A375	viability after 14 days	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	1.0120270085427914	[5]	[10,12]	9	hSpCas9	negative selection	3332997
88941780	88941803	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-1.0525290511409522	[291,342]	[0,0]	-7	hSpCas9	positive selection	3335385
88941221	88941244	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	1.153181441297366	[36,100]	[0,0]	5	hSpCas9	positive selection	3335386
88947347	88947370	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	2.4761379513696973	[26,27]	[0,0]	8	hSpCas9	positive selection	3335387
88947289	88947312	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	1.0285075209499543	[74,74]	[0,0]	5	hSpCas9	positive selection	3354635
88943829	88943852	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	1.7654731151161607	[44,44]	[0,0]	7	hSpCas9	positive selection	3354636
88941379	88941402	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.5818775766511088	[228,228]	[0,0]	-4	hSpCas9	positive selection	3354637
88948883	88948906	10	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-1.06389937809659	[]	[]	-9	hSpCas9	negative selection	3404622
88941818	88941841	10	-	26780180	HT29	viability (Avana library 4 designs)	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	-0.0865377494841958	[]	[]	-1	hSpCas9	negative selection	3404623
88947346	88947369	10	-	26780180	HT29	viability (Avana library 4 designs)	GGACAAAAAGACAGCTACGTGGG	ACTA2	ENSG00000107796	1.51358759244377	[]	[]	6	hSpCas9	negative selection	3404624
88947347	88947370	10	-	26780180	HT29	viability (Avana library 4 designs)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.0362220676940928	[]	[]	0	hSpCas9	negative selection	3404625
88941818	88941841	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	3.16718905450473	[]	[]	5	hSpCas9	negative selection	3476249
88947347	88947370	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	2.97921280014369	[]	[]	4	hSpCas9	negative selection	3476250
88947346	88947369	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAAAAAGACAGCTACGTGGG	ACTA2	ENSG00000107796	-1.09514628760845	[]	[]	-1	hSpCas9	negative selection	3476251
88948883	88948906	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-2.16565661631994	[]	[]	-3	hSpCas9	negative selection	3476252
88943838	88943861	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-2.64036008600289	[]	[]	-3	hSpCas9	negative selection	3476253
88941780	88941803	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	1.06722347430249	[]	[]	1	hSpCas9	negative selection	3476254
88941818	88941841	10	-	26780180	A375	viability (Avana lentiGuide)	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	-4.64044363089413	[]	[]	-7	hSpCas9	negative selection	3584908
88947347	88947370	10	-	26780180	A375	viability (Avana lentiGuide)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-1.40475545328042	[]	[]	-2	hSpCas9	negative selection	3584909
88947346	88947369	10	-	26780180	A375	viability (Avana lentiGuide)	GGACAAAAAGACAGCTACGTGGG	ACTA2	ENSG00000107796	1.66629252427363	[]	[]	2	hSpCas9	negative selection	3584910
88948883	88948906	10	+	26780180	A375	viability (Avana lentiGuide)	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.416469804210549	[]	[]	0	hSpCas9	negative selection	3584911
88943838	88943861	10	-	26780180	A375	viability (Avana lentiGuide)	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-2.01192630496314	[]	[]	-3	hSpCas9	negative selection	3584912
88941780	88941803	10	+	26780180	A375	viability (Avana lentiGuide)	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	1.60557934822085	[]	[]	1	hSpCas9	negative selection	3584913
88941818	88941841	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.15284443988952426	[4]	[5,4]	4	hSpCas9	positive selection	3693567
88947347	88947370	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.12961633243842904	[5]	[5,5]	3	hSpCas9	positive selection	3693568
88947346	88947369	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAAAAAGACAGCTACGTGGG	ACTA2	ENSG00000107796	-0.37351549584919225	[5]	[3,3]	-5	hSpCas9	positive selection	3693569
88948883	88948906	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.7083032764438059	[4]	[3,1]	-7	hSpCas9	positive selection	3693570
88943838	88943861	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-0.030313257313019842	[4]	[3,3]	0	hSpCas9	positive selection	3693571
88941780	88941803	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.1347929022817914	[4]	[5,4]	3	hSpCas9	positive selection	3693572
88941818	88941841	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.1303046603114746	[5]	[4,5]	3	hSpCas9	positive selection	3802174
88947347	88947370	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.156783161243236	[6]	[4,4]	-2	hSpCas9	positive selection	3802175
88947346	88947369	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAAAAAGACAGCTACGTGGG	ACTA2	ENSG00000107796	-0.42832556671413685	[5]	[2,3]	-5	hSpCas9	positive selection	3802176
88948883	88948906	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.4204738753100755	[5]	[5,6]	9	hSpCas9	positive selection	3802177
88943838	88943861	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.2747524278422597	[4]	[4,5]	7	hSpCas9	positive selection	3802178
88941780	88941803	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.17012500744840292	[5]	[5,5]	4	hSpCas9	positive selection	3802179
88941780	88941803	10	+	26780180	A375	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.754036848927544	[]	[]	3	hSpCas9	negative selection	3910785
88947289	88947312	10	-	26780180	A375	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	1.27779363701528	[]	[]	7	hSpCas9	negative selection	3910786
88941221	88941244	10	+	26780180	A375	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	1.58396923439536	[]	[]	8	hSpCas9	negative selection	3910787
88947347	88947370	10	-	26780180	A375	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.833643641664033	[]	[]	3	hSpCas9	negative selection	3910788
88943829	88943852	10	+	26780180	A375	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	1.15130576964224	[]	[]	6	hSpCas9	negative selection	3910789
88941379	88941402	10	-	26780180	A375	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	2.06425544003755	[]	[]	9	hSpCas9	negative selection	3910790
88941780	88941803	10	+	26780180	HT29	viability (GeCKOv2 library)	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.382302375973152	[]	[]	1	hSpCas9	negative selection	4018751
88947289	88947312	10	-	26780180	HT29	viability (GeCKOv2 library)	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.615144742352891	[]	[]	2	hSpCas9	negative selection	4018752
88941221	88941244	10	+	26780180	HT29	viability (GeCKOv2 library)	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	1.30055878947921	[]	[]	6	hSpCas9	negative selection	4018753
88947347	88947370	10	-	26780180	HT29	viability (GeCKOv2 library)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	1.34615715828633	[]	[]	6	hSpCas9	negative selection	4018754
88943829	88943852	10	+	26780180	HT29	viability (GeCKOv2 library)	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	1.86393897483896	[]	[]	8	hSpCas9	negative selection	4018755
88941379	88941402	10	-	26780180	HT29	viability (GeCKOv2 library)	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	1.23618338813584	[]	[]	6	hSpCas9	negative selection	4018756
88943877	88943900	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	-0.19675497595530123	[2]	[1,0]	-5	hSpCas9	positive selection	4187480
88947347	88947370	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	1.7641314690447307	[2]	[1,12]	9	hSpCas9	positive selection	4187493
88943829	88943852	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.06084277541775829	[2]	[1,0]	-1	hSpCas9	positive selection	4187504
88943877	88943900	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	-0.37451228819313576	[2]	[0,0,0,0]	-5	hSpCas9	positive selection	4251502
88947347	88947370	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.15410133341140497	[1]	[0,0,0,0]	-2	hSpCas9	positive selection	4251515
88943829	88943852	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.1716872244446349	[1]	[0,0,0,0]	-2	hSpCas9	positive selection	4251526
88941780	88941803	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.3720026985782115	[4]	[4,4]	7	hSpCas9	positive selection	4254302
88941221	88941244	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.30211247577950584	[2]	[2,0]	-6	hSpCas9	positive selection	4254303
88947347	88947370	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.14719434348232796	[1]	[1,0]	-3	hSpCas9	positive selection	4254304
88947289	88947312	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.09725021135883782	[2]	[1,1]	2	hSpCas9	positive selection	4318585
88943829	88943852	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.27975009701324666	[1]	[1,0]	-5	hSpCas9	positive selection	4318586
88941379	88941402	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.08307400814284668	[3]	[3,1]	-2	hSpCas9	positive selection	4318587
88941222	88941244	10	+	27760321	OCIAML3	viability	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.5935774171731785	[352,290]	[346,418]	7	hSpCas9	negative selection	4375842
88941781	88941803	10	+	27760321	OCIAML3	viability	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.11758313839524215	[1289,916]	[905,952]	1	hSpCas9	negative selection	4375843
88941818	88941840	10	-	27760321	OCIAML3	viability	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.4799931263455566	[401,429]	[426,494]	6	hSpCas9	negative selection	4375844
88943902	88943924	10	-	27760321	OCIAML3	viability	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	-0.16424831390179107	[580,437]	[333,376]	-2	hSpCas9	negative selection	4375845
88948806	88948828	10	+	27760321	OCIAML3	viability	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.5610624564788043	[320,299]	[232,521]	6	hSpCas9	negative selection	4375846
88941222	88941244	10	+	27760321	OCIAML2	viability	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.3944368232086105	[352,290]	[326,358]	5	hSpCas9	negative selection	4459305
88941781	88941803	10	+	27760321	OCIAML2	viability	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.04012153180734068	[1289,916]	[886,935]	0	hSpCas9	negative selection	4459306
88941818	88941840	10	-	27760321	OCIAML2	viability	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.12286395858508636	[401,429]	[334,412]	1	hSpCas9	negative selection	4459307
88943902	88943924	10	-	27760321	OCIAML2	viability	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	0.2762887850375873	[580,437]	[403,614]	3	hSpCas9	negative selection	4459308
88948806	88948828	10	+	27760321	OCIAML2	viability	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	-0.047013260805861934	[320,299]	[247,236]	0	hSpCas9	negative selection	4459309
88941222	88941244	10	+	27760321	MV411	viability	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.6312262928792478	[352,290]	[84,691]	4	hSpCas9	negative selection	4542768
88941781	88941803	10	+	27760321	MV411	viability	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	1.090663827488803	[1289,916]	[1583,1459]	7	hSpCas9	negative selection	4542769
88941818	88941840	10	-	27760321	MV411	viability	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.5308946521112303	[401,429]	[434,344]	4	hSpCas9	negative selection	4542770
88943902	88943924	10	-	27760321	MV411	viability	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	-0.7359665065315499	[580,437]	[210,183]	-5	hSpCas9	negative selection	4542771
88948806	88948828	10	+	27760321	MV411	viability	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.76569298422928	[320,299]	[280,449]	5	hSpCas9	negative selection	4542772
88941222	88941244	10	+	27760321	HL60	viability	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.13186727670823717	[352,290]	[315,255]	1	hSpCas9	negative selection	4626231
88941781	88941803	10	+	27760321	HL60	viability	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.13327063320094412	[1289,916]	[967,988]	1	hSpCas9	negative selection	4626232
88941818	88941840	10	-	27760321	HL60	viability	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.03217429168584671	[401,429]	[368,328]	0	hSpCas9	negative selection	4626233
88943902	88943924	10	-	27760321	HL60	viability	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	1.0156448248474552	[580,437]	[835,832]	9	hSpCas9	negative selection	4626234
88948806	88948828	10	+	27760321	HL60	viability	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.43669569290569116	[320,299]	[292,396]	5	hSpCas9	negative selection	4626235
88941222	88941244	10	+	27760321	HT1080	viability	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	1.4731206478157166	[290,226]	[263,310]	7	hSpCas9	negative selection	4709694
88941781	88941803	10	+	27760321	HT1080	viability	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.7582499578704478	[916,715]	[648,441]	4	hSpCas9	negative selection	4709695
88941818	88941840	10	-	27760321	HT1080	viability	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	-1.058372987271568	[429,335]	[99,43]	-4	hSpCas9	negative selection	4709696
88943902	88943924	10	-	27760321	HT1080	viability	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	2.052517391598231	[437,341]	[686,597]	9	hSpCas9	negative selection	4709697
88948806	88948828	10	+	27760321	HT1080	viability	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.2728965163656736	[299,233]	[212,35]	1	hSpCas9	negative selection	4709698
88941222	88941244	10	+	27760321	HT29	viability after 7 days	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.6998239206698127	[290,226]	[638,492,504]	9	hSpCas9	negative selection	4793157
88941781	88941803	10	+	27760321	HT29	viability after 7 days	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.11400808053544265	[916,715]	[1276,1367,792]	1	hSpCas9	negative selection	4793158
88941818	88941840	10	-	27760321	HT29	viability after 7 days	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.1920808664478779	[429,335]	[458,675,537]	3	hSpCas9	negative selection	4793159
88943902	88943924	10	-	27760321	HT29	viability after 7 days	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	0.13544920438182623	[437,341]	[711,551,414]	2	hSpCas9	negative selection	4793160
88948806	88948828	10	+	27760321	HT29	viability after 7 days	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	-0.09239292872845367	[299,233]	[206,385,354]	-1	hSpCas9	negative selection	4793161
88941222	88941244	10	+	27760321	HT29	viability after 25 days	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.843861388043508	[290,226]	[605,538,432]	8	hSpCas9	negative selection	4876620
88941781	88941803	10	+	27760321	HT29	viability after 25 days	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.6464551154504563	[916,715]	[1301,1357,1760]	7	hSpCas9	negative selection	4876621
88941818	88941840	10	-	27760321	HT29	viability after 25 days	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.1602286165064747	[429,335]	[318,560,609]	1	hSpCas9	negative selection	4876622
88943902	88943924	10	-	27760321	HT29	viability after 25 days	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	0.592837188224961	[437,341]	[737,467,820]	6	hSpCas9	negative selection	4876623
88948806	88948828	10	+	27760321	HT29	viability after 25 days	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.516752613997144	[299,233]	[372,330,628]	6	hSpCas9	negative selection	4876624
88941222	88941244	10	+	27760321	HT29	viability after 22 days	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.6626572768334204	[290,226]	[406,403,613]	7	hSpCas9	negative selection	4960083
88941781	88941803	10	+	27760321	HT29	viability after 22 days	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.5227363399748945	[916,715]	[1412,1487,1163]	6	hSpCas9	negative selection	4960084
88941818	88941840	10	-	27760321	HT29	viability after 22 days	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.0926631813523314	[429,335]	[577,325,509]	0	hSpCas9	negative selection	4960085
88943902	88943924	10	-	27760321	HT29	viability after 22 days	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	0.6649812238605908	[437,341]	[714,777,650]	7	hSpCas9	negative selection	4960086
88948806	88948828	10	+	27760321	HT29	viability after 22 days	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.47433859884343904	[299,233]	[376,356,554]	5	hSpCas9	negative selection	4960087
88941222	88941244	10	+	27760321	HT29	viability after 19 days	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.5321276823838357	[290,226]	[363,459,452]	5	hSpCas9	negative selection	5043546
88941781	88941803	10	+	27760321	HT29	viability after 19 days	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.7777574850622377	[916,715]	[1551,1432,1803]	7	hSpCas9	negative selection	5043547
88941818	88941840	10	-	27760321	HT29	viability after 19 days	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.42839868763989286	[429,335]	[407,586,747]	4	hSpCas9	negative selection	5043548
88943902	88943924	10	-	27760321	HT29	viability after 19 days	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	0.571523264439902	[437,341]	[807,710,490]	6	hSpCas9	negative selection	5043549
88948806	88948828	10	+	27760321	HT29	viability after 19 days	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.6024633535703434	[299,233]	[394,300,678]	6	hSpCas9	negative selection	5043550
88941222	88941244	10	+	27760321	HT29	viability after 16 days	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.9733537279434847	[290,226]	[589,478,641]	9	hSpCas9	negative selection	5127009
88941781	88941803	10	+	27760321	HT29	viability after 16 days	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.4585058239893842	[916,715]	[1744,946,1127]	5	hSpCas9	negative selection	5127010
88941818	88941840	10	-	27760321	HT29	viability after 16 days	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.2285985428546192	[429,335]	[587,362,566]	2	hSpCas9	negative selection	5127011
88943902	88943924	10	-	27760321	HT29	viability after 16 days	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	0.6795242411848423	[437,341]	[848,914,340]	7	hSpCas9	negative selection	5127012
88948806	88948828	10	+	27760321	HT29	viability after 16 days	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.22953803883896803	[299,233]	[303,244,499]	2	hSpCas9	negative selection	5127013
88941222	88941244	10	+	27760321	HT29	viability after 13 days	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.512257601677321	[290,226]	[345,566,375]	6	hSpCas9	negative selection	5210472
88941781	88941803	10	+	27760321	HT29	viability after 13 days	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.3420780653353861	[916,715]	[1325,1012,1258]	4	hSpCas9	negative selection	5210473
88941818	88941840	10	-	27760321	HT29	viability after 13 days	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.11174131409685176	[429,335]	[466,401,565]	1	hSpCas9	negative selection	5210474
88943902	88943924	10	-	27760321	HT29	viability after 13 days	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	0.4287308451051686	[437,341]	[773,518,537]	5	hSpCas9	negative selection	5210475
88948806	88948828	10	+	27760321	HT29	viability after 13 days	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.2556249133693949	[299,233]	[393,426,292]	3	hSpCas9	negative selection	5210476
88941222	88941244	10	+	27760321	HT29	viability after 10 days	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.6303071950857675	[290,226]	[519,340,632]	8	hSpCas9	negative selection	5293935
88941781	88941803	10	+	27760321	HT29	viability after 10 days	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.16294705943394727	[916,715]	[1189,1120,1112]	2	hSpCas9	negative selection	5293936
88941818	88941840	10	-	27760321	HT29	viability after 10 days	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	0.3581440311745562	[429,335]	[703,514,616]	5	hSpCas9	negative selection	5293937
88943902	88943924	10	-	27760321	HT29	viability after 10 days	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	1.0305999824394343	[437,341]	[1285,820,874]	9	hSpCas9	negative selection	5293938
88948806	88948828	10	+	27760321	HT29	viability after 10 days	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	0.47455157682176313	[299,233]	[340,467,577]	6	hSpCas9	negative selection	5293939
88941222	88941244	10	+	27760321	MOLM13	viability	GCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.150289949594205	[352,290]	[156,167]	-1	hSpCas9	negative selection	5377398
88941781	88941803	10	+	27760321	MOLM13	viability	CTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.597051701678734	[1289,916]	[833,1014]	4	hSpCas9	negative selection	5377399
88941818	88941840	10	-	27760321	MOLM13	viability	ATGTATGTGGCTATCCAGGCGG	ACTA2	ENSG00000107796	1.409225144740778	[401,429]	[853,433]	8	hSpCas9	negative selection	5377400
88943902	88943924	10	-	27760321	MOLM13	viability	TCCCCCAACTCACTAGATCTGG	ACTA2	ENSG00000107796	1.064799937785061	[580,437]	[550,634]	7	hSpCas9	negative selection	5377401
88948806	88948828	10	+	27760321	MOLM13	viability	TGTCTGGGACGTCCCACAATGG	ACTA2	ENSG00000107796	1.068783970931324	[320,299]	[230,483]	7	hSpCas9	negative selection	5377402
88952693	88952716	10	+	27661255	K562	viability	GAATCTATAAGTCACATCCTTGG	ACTA2	ENSG00000107796	0.03237590546639613	[2162,2728]	[2153,1849]	1	dCas9-KRAB	negative selection	5460697
88952519	88952542	10	-	27661255	K562	viability	GTAGTTTGGTATGATGGAAGGGG	ACTA2	ENSG00000107796	0.13140747141694556	[630,828]	[667,607]	4	dCas9-KRAB	negative selection	5460700
88952533	88952556	10	-	27661255	K562	viability	GACAGGGCTAATATGTAGTTTGG	ACTA2	ENSG00000107796	0.09773054690720279	[805,1048]	[821,760]	3	dCas9-KRAB	negative selection	5460701
88941780	88941803	10	+	27260156	BXPC3	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.16967250365261255	[1262]	[1470,1457,1335,1691]	4	hSpCas9	negative selection	5526762
88941221	88941244	10	+	27260156	BXPC3	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.13401234852734212	[276]	[246,228,349,228]	-3	hSpCas9	negative selection	5526763
88947347	88947370	10	-	27260156	BXPC3	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.17332811133784354	[107]	[113,44,129,114]	-4	hSpCas9	negative selection	5526764
88947289	88947312	10	-	27260156	BXPC3	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.16882366501674562	[233]	[379,214,253,235]	4	hSpCas9	negative selection	5591045
88943829	88943852	10	+	27260156	BXPC3	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.2955341908666451	[192]	[115,191,192,158]	-6	hSpCas9	negative selection	5591046
88941379	88941402	10	-	27260156	BXPC3	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.253078835985429	[760]	[621,693,657,698]	-5	hSpCas9	negative selection	5591047
88941780	88941803	10	+	27260156	A673	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.0684311233097048	[1262]	[1705,1458,1634,1572]	1	hSpCas9	negative selection	5648013
88941221	88941244	10	+	27260156	A673	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.16793550011253144	[276]	[343,252,344,244]	-4	hSpCas9	negative selection	5648014
88947347	88947370	10	-	27260156	A673	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.19980980270942705	[107]	[98,121,137,88]	-5	hSpCas9	negative selection	5648015
88947289	88947312	10	-	27260156	A673	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.20829146605481896	[233]	[372,229,353,349]	5	hSpCas9	negative selection	5712296
88943829	88943852	10	+	27260156	A673	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.19071548716323394	[192]	[234,226,183,166]	-5	hSpCas9	negative selection	5712297
88941379	88941402	10	-	27260156	A673	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.1075086426621571	[760]	[915,810,851,818]	-3	hSpCas9	negative selection	5712298
88941780	88941803	10	+	27260156	A375	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.15417924719878373	[1262]	[1583,1399,1030,1297]	-2	hSpCas9	negative selection	5769264
88941221	88941244	10	+	27260156	A375	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-1.0836064906670064	[276]	[202,154,157,100]	-8	hSpCas9	negative selection	5769265
88947347	88947370	10	-	27260156	A375	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.489259716683236	[107]	[43,72,80,150]	-6	hSpCas9	negative selection	5769266
88947289	88947312	10	-	27260156	A375	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.07314392435732597	[233]	[213,259,358,308]	1	hSpCas9	negative selection	5833547
88943829	88943852	10	+	27260156	A375	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.3612617718315414	[192]	[141,199,182,178]	-5	hSpCas9	negative selection	5833548
88941379	88941402	10	-	27260156	A375	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.3601723567511554	[760]	[600,797,567,800]	-5	hSpCas9	negative selection	5833549
88941780	88941803	10	+	27260156	COLO741	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.1614123946161823	[1262]	[2013,1920,1514]	3	hSpCas9	negative selection	5890515
88941221	88941244	10	+	27260156	COLO741	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.2258044238904715	[276]	[442,425,376]	5	hSpCas9	negative selection	5890516
88947347	88947370	10	-	27260156	COLO741	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.2938280516572629	[107]	[189,151,166]	6	hSpCas9	negative selection	5890517
88947289	88947312	10	-	27260156	COLO741	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.03294198573322138	[233]	[256,335,280]	0	hSpCas9	negative selection	5954798
88943829	88943852	10	+	27260156	COLO741	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.61040080829511	[192]	[216,126,145]	-8	hSpCas9	negative selection	5954799
88941379	88941402	10	-	27260156	COLO741	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	0.07164033882287413	[760]	[1271,874,942]	1	hSpCas9	negative selection	5954800
88941780	88941803	10	+	27260156	CAL120	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.2633350763359772	[1262]	[1248,1544,1127]	-4	hSpCas9	negative selection	6011766
88941221	88941244	10	+	27260156	CAL120	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.2847323610720631	[276]	[191,411,231]	-4	hSpCas9	negative selection	6011767
88947347	88947370	10	-	27260156	CAL120	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-1.0436972118948282	[107]	[83,27,85]	-8	hSpCas9	negative selection	6011768
88947289	88947312	10	-	27260156	CAL120	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.24867997265280883	[233]	[214,235,278]	-4	hSpCas9	negative selection	6076049
88943829	88943852	10	+	27260156	CAL120	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.7335721564225597	[192]	[190,145,103]	-8	hSpCas9	negative selection	6076050
88941379	88941402	10	-	27260156	CAL120	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.4912836999637796	[760]	[771,615,647]	-6	hSpCas9	negative selection	6076051
88941780	88941803	10	+	27260156	CADOES1	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.24512249301060618	[1262]	[1031,1023,1004,899]	-4	hSpCas9	negative selection	6133017
88941221	88941244	10	+	27260156	CADOES1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.48375050146554077	[276]	[293,181,118,139]	-7	hSpCas9	negative selection	6133018
88947347	88947370	10	-	27260156	CADOES1	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.47146631438433895	[107]	[126,41,62,56]	-7	hSpCas9	negative selection	6133019
88947289	88947312	10	-	27260156	CADOES1	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.09106264725172619	[233]	[237,144,256,175]	-1	hSpCas9	negative selection	6197300
88943829	88943852	10	+	27260156	CADOES1	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.3512804132488452	[192]	[85,217,121,136]	-6	hSpCas9	negative selection	6197301
88941379	88941402	10	-	27260156	CADOES1	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.3236265213174099	[760]	[522,511,589,639]	-5	hSpCas9	negative selection	6197302
88941780	88941803	10	+	27260156	EWS502	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.11474743773439378	[1262]	[1355,1169,1397,1919]	2	hSpCas9	negative selection	6254268
88941221	88941244	10	+	27260156	EWS502	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.23614464594083284	[276]	[235,278,255,222]	-4	hSpCas9	negative selection	6254269
88947347	88947370	10	-	27260156	EWS502	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.08561643613184033	[107]	[73,90,152,118]	-1	hSpCas9	negative selection	6254270
88947289	88947312	10	-	27260156	EWS502	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.16817110793448764	[233]	[153,214,202,324]	-3	hSpCas9	negative selection	6318551
88943829	88943852	10	+	27260156	EWS502	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.6013685099176538	[192]	[123,100,81,240]	-7	hSpCas9	negative selection	6318552
88941379	88941402	10	-	27260156	EWS502	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.14477815238264125	[760]	[720,598,755,852]	-3	hSpCas9	negative selection	6318553
88941780	88941803	10	+	27260156	EW8	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.14508161287038646	[1262]	[899,771,1103,889]	-3	hSpCas9	negative selection	6375519
88941221	88941244	10	+	27260156	EW8	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.4117003728023494	[276]	[93,141,185,240]	-6	hSpCas9	negative selection	6375520
88947347	88947370	10	-	27260156	EW8	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.4843253592861936	[107]	[58,145,178,88]	8	hSpCas9	negative selection	6375521
88947289	88947312	10	-	27260156	EW8	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.04640135106102172	[233]	[289,189,147,123]	-1	hSpCas9	negative selection	6439802
88943829	88943852	10	+	27260156	EW8	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.7259620086561303	[192]	[169,60,83,72]	-8	hSpCas9	negative selection	6439803
88941379	88941402	10	-	27260156	EW8	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.3618378760542092	[760]	[545,709,362,327]	-6	hSpCas9	negative selection	6439804
88941780	88941803	10	+	27260156	CORL105	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.10824898778096559	[1262]	[1643,1339,2009,1452]	2	hSpCas9	negative selection	6496770
88941221	88941244	10	+	27260156	CORL105	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.0157783396770802	[276]	[380,281,408,254]	0	hSpCas9	negative selection	6496771
88947347	88947370	10	-	27260156	CORL105	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.6963045410689279	[107]	[368,119,185,148]	9	hSpCas9	negative selection	6496772
88947289	88947312	10	-	27260156	CORL105	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.1046119647329562	[233]	[241,231,242,299]	-2	hSpCas9	negative selection	6561053
88943829	88943852	10	+	27260156	CORL105	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.38723575233701757	[192]	[142,167,185,194]	-6	hSpCas9	negative selection	6561054
88941379	88941402	10	-	27260156	CORL105	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.17616500324446427	[760]	[792,921,814,625]	-3	hSpCas9	negative selection	6561055
88941780	88941803	10	+	27260156	HS294T	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.5103219932222178	[1262]	[531,646,1050,541]	6	hSpCas9	negative selection	6618021
88941221	88941244	10	+	27260156	HS294T	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.12925304919430836	[276]	[97,73,119,191]	1	hSpCas9	negative selection	6618022
88947347	88947370	10	-	27260156	HS294T	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.5817627667497876	[107]	[42,50,125,25]	7	hSpCas9	negative selection	6618023
88947289	88947312	10	-	27260156	HS294T	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.12782968899348957	[233]	[70,103,131,88]	1	hSpCas9	negative selection	6682304
88943829	88943852	10	+	27260156	HS294T	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.5101377620952126	[192]	[31,37,78,64]	-6	hSpCas9	negative selection	6682305
88941379	88941402	10	-	27260156	HS294T	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	0.11737287401071039	[760]	[334,272,336,332]	1	hSpCas9	negative selection	6682306
88941780	88941803	10	+	27260156	HCC44	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.22650374658197414	[1262]	[2115,1353,1886,1444]	3	hSpCas9	negative selection	6739272
88941221	88941244	10	+	27260156	HCC44	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.6123727307432709	[276]	[277,70,309,202]	-7	hSpCas9	negative selection	6739273
88947347	88947370	10	-	27260156	HCC44	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.4120749158537227	[107]	[84,219,260,86]	6	hSpCas9	negative selection	6739274
88947289	88947312	10	-	27260156	HCC44	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.09005415571377284	[233]	[233,256,213,277]	-1	hSpCas9	negative selection	6803555
88943829	88943852	10	+	27260156	HCC44	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	0.13085489230761405	[192]	[213,221,369,172]	2	hSpCas9	negative selection	6803556
88941379	88941402	10	-	27260156	HCC44	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.13759988516947108	[760]	[754,575,973,874]	-2	hSpCas9	negative selection	6803557
88941780	88941803	10	+	27260156	G402	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.019876841437860948	[1262]	[1789,1361,1431,1519]	0	hSpCas9	negative selection	6860523
88941221	88941244	10	+	27260156	G402	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.0840708912794863	[276]	[462,237,199,385]	-1	hSpCas9	negative selection	6860524
88947347	88947370	10	-	27260156	G402	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.6223867612381762	[107]	[347,106,81,284]	7	hSpCas9	negative selection	6860525
88947289	88947312	10	-	27260156	G402	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.5508534279413275	[233]	[408,78,97,215]	-6	hSpCas9	negative selection	6924806
88943829	88943852	10	+	27260156	G402	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.8904994504163828	[192]	[271,84,123,48]	-8	hSpCas9	negative selection	6924807
88941379	88941402	10	-	27260156	G402	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	0.04772623490883532	[760]	[1449,1032,625,808]	0	hSpCas9	negative selection	6924808
88941780	88941803	10	+	27260156	L33	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.005059829457328968	[1262]	[1212,502,897,1202]	0	hSpCas9	negative selection	6981774
88941221	88941244	10	+	27260156	L33	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.3483617436941442	[276]	[230,164,272,345]	7	hSpCas9	negative selection	6981775
88947347	88947370	10	-	27260156	L33	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.16917612098547474	[107]	[108,38,76,158]	4	hSpCas9	negative selection	6981776
88947289	88947312	10	-	27260156	L33	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.592581167510896	[233]	[264,116,350,305]	9	hSpCas9	negative selection	7046057
88943829	88943852	10	+	27260156	L33	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.390230113688784	[192]	[190,33,104,146]	-7	hSpCas9	negative selection	7046058
88941379	88941402	10	-	27260156	L33	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.21784594052013317	[760]	[688,258,367,708]	-5	hSpCas9	negative selection	7046059
88941780	88941803	10	+	27260156	K562	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.02241478556929044	[1262]	[948,1371,1006,1208]	0	hSpCas9	negative selection	7103025
88941221	88941244	10	+	27260156	K562	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.2542552820962787	[276]	[324,126,491,228]	3	hSpCas9	negative selection	7103026
88947347	88947370	10	-	27260156	K562	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.6561876173861949	[107]	[52,62,343,132]	8	hSpCas9	negative selection	7103027
88947289	88947312	10	-	27260156	K562	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.43637112585935367	[233]	[187,111,427,367]	5	hSpCas9	negative selection	7167308
88943829	88943852	10	+	27260156	K562	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.40814125855648675	[192]	[111,80,266,59]	-5	hSpCas9	negative selection	7167309
88941379	88941402	10	-	27260156	K562	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	0.014726681289229826	[760]	[672,722,502,812]	0	hSpCas9	negative selection	7167310
88941780	88941803	10	+	27260156	HT29	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.08202820751561601	[1262]	[1579,1929,1641,1388]	1	hSpCas9	negative selection	7224276
88941221	88941244	10	+	27260156	HT29	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.2606494009005027	[276]	[368,528,399,329]	5	hSpCas9	negative selection	7224277
88947347	88947370	10	-	27260156	HT29	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.2925523876877292	[107]	[220,84,180,153]	6	hSpCas9	negative selection	7224278
88947289	88947312	10	-	27260156	HT29	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.05535717556956765	[233]	[329,229,319,296]	1	hSpCas9	negative selection	7288559
88943829	88943852	10	+	27260156	HT29	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.15349802181769712	[192]	[190,214,223,210]	-3	hSpCas9	negative selection	7288560
88941379	88941402	10	-	27260156	HT29	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.06342548491541122	[760]	[755,1035,907,842]	-1	hSpCas9	negative selection	7288561
88941780	88941803	10	+	27260156	MHHES1	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.05011260114349181	[1262]	[1682,1833,1410,1082]	0	hSpCas9	negative selection	7345527
88941221	88941244	10	+	27260156	MHHES1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.23308027135566178	[276]	[180,466,277,163]	-4	hSpCas9	negative selection	7345528
88947347	88947370	10	-	27260156	MHHES1	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.38753191971915757	[107]	[149,160,121,190]	7	hSpCas9	negative selection	7345529
88947289	88947312	10	-	27260156	MHHES1	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.13583410769416004	[233]	[287,276,365,232]	2	hSpCas9	negative selection	7409810
88943829	88943852	10	+	27260156	MHHES1	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.4747154887781255	[192]	[86,265,228,64]	-7	hSpCas9	negative selection	7409811
88941379	88941402	10	-	27260156	MHHES1	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.30438131096516996	[760]	[604,780,925,494]	-5	hSpCas9	negative selection	7409812
88941780	88941803	10	+	27260156	MEWO	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.12804435761912503	[1262]	[1415,1233,1247]	3	hSpCas9	negative selection	7466778
88941221	88941244	10	+	27260156	MEWO	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.36683023042450835	[276]	[214,113,276]	-7	hSpCas9	negative selection	7466779
88947347	88947370	10	-	27260156	MEWO	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.4283858773644884	[107]	[182,135,97]	8	hSpCas9	negative selection	7466780
88947289	88947312	10	-	27260156	MEWO	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.09256756105756703	[233]	[293,226,190]	2	hSpCas9	negative selection	7531061
88943829	88943852	10	+	27260156	MEWO	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	0.08672697382380501	[192]	[225,159,195]	2	hSpCas9	negative selection	7531062
88941379	88941402	10	-	27260156	MEWO	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.11613463653146872	[760]	[672,792,506]	-3	hSpCas9	negative selection	7531063
88941780	88941803	10	+	27260156	LNCAPCLONEFGC	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.37554705041015923	[1262]	[1195,1586,1693,1488]	6	hSpCas9	negative selection	7588029
88941221	88941244	10	+	27260156	LNCAPCLONEFGC	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.18678687544849804	[276]	[290,242,285,324]	3	hSpCas9	negative selection	7588030
88947347	88947370	10	-	27260156	LNCAPCLONEFGC	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.32547370208227355	[107]	[156,83,107,140]	5	hSpCas9	negative selection	7588031
88947289	88947312	10	-	27260156	LNCAPCLONEFGC	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.3901086458830495	[233]	[305,261,294,250]	6	hSpCas9	negative selection	7652312
88943829	88943852	10	+	27260156	LNCAPCLONEFGC	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.5717416795514152	[192]	[130,110,153,79]	-7	hSpCas9	negative selection	7652313
88941379	88941402	10	-	27260156	LNCAPCLONEFGC	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	0.03610738277205627	[760]	[673,588,1095,533]	0	hSpCas9	negative selection	7652314
88941780	88941803	10	+	27260156	PANC0327	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.24080865438054566	[1262]	[1421,565,1033,863]	-4	hSpCas9	negative selection	7709280
88941221	88941244	10	+	27260156	PANC0327	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.05085559092760561	[276]	[415,243,174,198]	0	hSpCas9	negative selection	7709281
88947347	88947370	10	-	27260156	PANC0327	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.8146629158504097	[107]	[118,398,58,63]	9	hSpCas9	negative selection	7709282
88947289	88947312	10	-	27260156	PANC0327	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.1071724980945794	[233]	[144,222,169,225]	-2	hSpCas9	negative selection	7773563
88943829	88943852	10	+	27260156	PANC0327	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	0.8462138896028297	[192]	[226,125,116,778]	9	hSpCas9	negative selection	7773564
88941379	88941402	10	-	27260156	PANC0327	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.20258128537216707	[760]	[588,407,692,682]	-3	hSpCas9	negative selection	7773565
88941780	88941803	10	+	27260156	NCIH2009	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.23190241025030334	[1262]	[2450,1923,1915]	3	hSpCas9	negative selection	7830531
88941221	88941244	10	+	27260156	NCIH2009	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.4099749820534506	[276]	[303,249,950]	5	hSpCas9	negative selection	7830532
88947347	88947370	10	-	27260156	NCIH2009	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.1786398141045118	[107]	[273,85,173]	2	hSpCas9	negative selection	7830533
88947289	88947312	10	-	27260156	NCIH2009	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.24413158669729562	[233]	[325,380,441]	3	hSpCas9	negative selection	7894814
88943829	88943852	10	+	27260156	NCIH2009	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.059451861171510245	[192]	[236,123,412]	-1	hSpCas9	negative selection	7894815
88941379	88941402	10	-	27260156	NCIH2009	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.17508440079824117	[760]	[914,1012,888]	-2	hSpCas9	negative selection	7894816
88941780	88941803	10	+	27260156	NCIH1373	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.014955362957119522	[1262]	[1365,828,1676,472]	0	hSpCas9	negative selection	7951782
88941221	88941244	10	+	27260156	NCIH1373	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.7292849468979792	[276]	[95,218,157,68]	-6	hSpCas9	negative selection	7951783
88947347	88947370	10	-	27260156	NCIH1373	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.6714059860022545	[107]	[94,217,159,74]	6	hSpCas9	negative selection	7951784
88947289	88947312	10	-	27260156	NCIH1373	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.42484513243192024	[233]	[93,237,120,82]	-4	hSpCas9	negative selection	8016065
88943829	88943852	10	+	27260156	NCIH1373	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.08634773174882393	[192]	[334,219,116,41]	-1	hSpCas9	negative selection	8016066
88941379	88941402	10	-	27260156	NCIH1373	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.159656375743904	[760]	[940,727,429,263]	-1	hSpCas9	negative selection	8016067
88941780	88941803	10	+	27260156	PATU8902	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.39793012955738205	[1262]	[1011,1268,1652,1313]	-4	hSpCas9	negative selection	8073033
88941221	88941244	10	+	27260156	PATU8902	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-1.128632062346644	[276]	[237,326,101,39]	-7	hSpCas9	negative selection	8073034
88947347	88947370	10	-	27260156	PATU8902	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.4780595064399533	[107]	[112,42,500,89]	5	hSpCas9	negative selection	8073035
88947289	88947312	10	-	27260156	PATU8902	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.3407872998016416	[233]	[181,332,610,480]	3	hSpCas9	negative selection	8137316
88943829	88943852	10	+	27260156	PATU8902	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	0.01951771283664261	[192]	[202,528,16,424]	0	hSpCas9	negative selection	8137317
88941379	88941402	10	-	27260156	PATU8902	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.12718897480623803	[760]	[964,1217,686,1092]	-1	hSpCas9	negative selection	8137318
88941780	88941803	10	+	27260156	PANC1	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.07725597883864599	[1262]	[993,1547,1311,842]	1	hSpCas9	negative selection	8194284
88941221	88941244	10	+	27260156	PANC1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.1917003148249652	[276]	[322,346,128,77]	-3	hSpCas9	negative selection	8194285
88947347	88947370	10	-	27260156	PANC1	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.41434227666991497	[107]	[49,119,35,79]	-6	hSpCas9	negative selection	8194286
88947289	88947312	10	-	27260156	PANC1	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.013349467132848791	[233]	[123,385,174,167]	0	hSpCas9	negative selection	8258567
88943829	88943852	10	+	27260156	PANC1	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.6241382824675343	[192]	[50,239,87,81]	-7	hSpCas9	negative selection	8258568
88941379	88941402	10	-	27260156	PANC1	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.03130377677349028	[760]	[679,732,704,475]	0	hSpCas9	negative selection	8258569
88941780	88941803	10	+	27260156	PANC0813	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.30808122549431016	[1262]	[1876,1666,2097,1713]	5	hSpCas9	negative selection	8315535
88941221	88941244	10	+	27260156	PANC0813	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.06446700936466387	[276]	[384,253,284,325]	-1	hSpCas9	negative selection	8315536
88947347	88947370	10	-	27260156	PANC0813	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.07263918695591487	[107]	[209,74,147,108]	1	hSpCas9	negative selection	8315537
88947289	88947312	10	-	27260156	PANC0813	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.12972686720541093	[233]	[459,272,292,196]	2	hSpCas9	negative selection	8379818
88943829	88943852	10	+	27260156	PANC0813	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.15352100571012683	[192]	[277,218,233,96]	-3	hSpCas9	negative selection	8379819
88941379	88941402	10	-	27260156	PANC0813	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.08854426553027905	[760]	[832,715,793,1007]	-1	hSpCas9	negative selection	8379820
88941780	88941803	10	+	27260156	RDES	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.1379473814831007	[1262]	[1119,1196,1271,1772]	-2	hSpCas9	negative selection	8436786
88941221	88941244	10	+	27260156	RDES	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.2652333955669828	[276]	[242,236,264,322]	-4	hSpCas9	negative selection	8436787
88947347	88947370	10	-	27260156	RDES	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.03786976185160018	[107]	[91,116,168,108]	0	hSpCas9	negative selection	8436788
88947289	88947312	10	-	27260156	RDES	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.06122966640324634	[233]	[254,168,340,272]	-1	hSpCas9	negative selection	8501069
88943829	88943852	10	+	27260156	RDES	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.5655133317979304	[192]	[72,313,58,145]	-7	hSpCas9	negative selection	8501070
88941379	88941402	10	-	27260156	RDES	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.17138116823056326	[760]	[682,821,830,762]	-3	hSpCas9	negative selection	8501071
88941780	88941803	10	+	27260156	PC3	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.15215341569383423	[1262]	[813,887,1729,1372]	-3	hSpCas9	negative selection	8558037
88941221	88941244	10	+	27260156	PC3	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.2966749525305712	[276]	[137,143,311,366]	-6	hSpCas9	negative selection	8558038
88947347	88947370	10	-	27260156	PC3	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.30487069072537665	[107]	[89,50,108,94]	-6	hSpCas9	negative selection	8558039
88947289	88947312	10	-	27260156	PC3	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.6338938574699542	[233]	[289,241,614,395]	9	hSpCas9	negative selection	8622320
88943829	88943852	10	+	27260156	PC3	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.10602549182746812	[192]	[143,174,217,186]	-2	hSpCas9	negative selection	8622321
88941379	88941402	10	-	27260156	PC3	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.13436752912318584	[760]	[397,596,928,1018]	-3	hSpCas9	negative selection	8622322
88941780	88941803	10	+	27260156	PATU8988T	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.33272443747099256	[1262]	[721,1415,725,1064]	-5	hSpCas9	negative selection	8679288
88941221	88941244	10	+	27260156	PATU8988T	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.2689105365714197	[276]	[323,262,126,175]	-4	hSpCas9	negative selection	8679289
88947347	88947370	10	-	27260156	PATU8988T	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.1834104836531545	[107]	[107,215,72,83]	3	hSpCas9	negative selection	8679290
88947289	88947312	10	-	27260156	PATU8988T	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.1607163819255809	[233]	[204,250,253,304]	2	hSpCas9	negative selection	8743571
88943829	88943852	10	+	27260156	PATU8988T	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.50385706222254	[192]	[84,188,130,125]	-7	hSpCas9	negative selection	8743572
88941379	88941402	10	-	27260156	PATU8988T	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	0.1136619214823561	[760]	[1070,959,548,605]	2	hSpCas9	negative selection	8743573
88941780	88941803	10	+	27260156	T47D	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.16731769197348778	[1262]	[1213,1176,1486,1372]	-4	hSpCas9	negative selection	8800539
88941221	88941244	10	+	27260156	T47D	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.5376596631789146	[276]	[254,175,199,263]	-8	hSpCas9	negative selection	8800540
88947347	88947370	10	-	27260156	T47D	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.1368361086348322	[107]	[137,151,150,109]	3	hSpCas9	negative selection	8800541
88947289	88947312	10	-	27260156	T47D	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.10885180438354636	[233]	[334,274,312,252]	2	hSpCas9	negative selection	8864822
88943829	88943852	10	+	27260156	T47D	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.28661419903452967	[192]	[173,180,142,241]	-6	hSpCas9	negative selection	8864823
88941379	88941402	10	-	27260156	T47D	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.04618074301827246	[760]	[917,824,911,778]	-1	hSpCas9	negative selection	8864824
88941780	88941803	10	+	27260156	SU8686	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.0486907088884132	[1262]	[1045,1220,1222,1798]	0	hSpCas9	negative selection	8921790
88941221	88941244	10	+	27260156	SU8686	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.5662322997137508	[276]	[307,369,364,631]	8	hSpCas9	negative selection	8921791
88947347	88947370	10	-	27260156	SU8686	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.6964711814423363	[107]	[210,210,104,150]	9	hSpCas9	negative selection	8921792
88947289	88947312	10	-	27260156	SU8686	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.06272946525061962	[233]	[177,218,185,324]	-1	hSpCas9	negative selection	8986073
88943829	88943852	10	+	27260156	SU8686	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.1978909922934513	[192]	[109,112,212,259]	-3	hSpCas9	negative selection	8986074
88941379	88941402	10	-	27260156	SU8686	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.08009134935584994	[760]	[755,669,606,833]	-1	hSpCas9	negative selection	8986075
88941780	88941803	10	+	27260156	SKES1	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.028434206892134606	[1262]	[1731,1045,1307,1095]	0	hSpCas9	negative selection	9043041
88941221	88941244	10	+	27260156	SKES1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.05619446643119563	[276]	[304,417,146,220]	-1	hSpCas9	negative selection	9043042
88947347	88947370	10	-	27260156	SKES1	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.10050957454734855	[107]	[118,117,99,71]	-2	hSpCas9	negative selection	9043043
88947289	88947312	10	-	27260156	SKES1	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.07350379660145712	[233]	[209,296,214,175]	-2	hSpCas9	negative selection	9107324
88943829	88943852	10	+	27260156	SKES1	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.6717984712986784	[192]	[124,155,122,86]	-9	hSpCas9	negative selection	9107325
88941379	88941402	10	-	27260156	SKES1	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.32057520842433734	[760]	[507,607,622,664]	-6	hSpCas9	negative selection	9107326
88941780	88941803	10	+	27260156	TOV112D	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.03984695988954412	[1262]	[1185,1690,1228,931]	-1	hSpCas9	negative selection	9164292
88941221	88941244	10	+	27260156	TOV112D	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.011363083511456762	[276]	[237,311,336,220]	0	hSpCas9	negative selection	9164293
88947347	88947370	10	-	27260156	TOV112D	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	-0.3634605126529684	[107]	[47,102,73,111]	-6	hSpCas9	negative selection	9164294
88947289	88947312	10	-	27260156	TOV112D	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.13427698504751984	[233]	[208,232,86,325]	-3	hSpCas9	negative selection	9228575
88943829	88943852	10	+	27260156	TOV112D	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.5018209584669076	[192]	[191,186,122,62]	-7	hSpCas9	negative selection	9228576
88941379	88941402	10	-	27260156	TOV112D	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.22128557826437556	[760]	[691,803,638,522]	-4	hSpCas9	negative selection	9228577
88941780	88941803	10	+	27260156	TC71	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.060457581119212955	[1262]	[1466,1402,1229,1560]	1	hSpCas9	negative selection	9285543
88941221	88941244	10	+	27260156	TC71	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.02232462189972184	[276]	[364,327,219,293]	0	hSpCas9	negative selection	9285544
88947347	88947370	10	-	27260156	TC71	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.18852089214128043	[107]	[171,124,87,143]	5	hSpCas9	negative selection	9285545
88947289	88947312	10	-	27260156	TC71	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	-0.12132321586670347	[233]	[185,296,200,240]	-3	hSpCas9	negative selection	9349826
88943829	88943852	10	+	27260156	TC71	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.1787310169624845	[192]	[227,164,174,160]	-5	hSpCas9	negative selection	9349827
88941379	88941402	10	-	27260156	TC71	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.128154328588867	[760]	[753,740,877,598]	-3	hSpCas9	negative selection	9349828
88941780	88941803	10	+	27260156	TC32	viability	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	-0.1341745464162496	[1262]	[1052,640,1546,1286]	-2	hSpCas9	negative selection	9406794
88941221	88941244	10	+	27260156	TC32	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.17494196041167354	[276]	[172,195,263,305]	-3	hSpCas9	negative selection	9406795
88947347	88947370	10	-	27260156	TC32	viability	GGGACAAAAAGACAGCTACGTGG	ACTA2	ENSG00000107796	0.07215028800379031	[107]	[58,91,167,124]	1	hSpCas9	negative selection	9406796
88947289	88947312	10	-	27260156	TC32	viability	CTGAAGTACCCGATAGAACATGG	ACTA2	ENSG00000107796	0.16609056865867577	[233]	[229,184,326,270]	3	hSpCas9	negative selection	9471077
88943829	88943852	10	+	27260156	TC32	viability	TCAGGGGTGCCTCCGTGAGCAGG	ACTA2	ENSG00000107796	-0.27484257050411953	[192]	[189,73,184,172]	-5	hSpCas9	negative selection	9471078
88941379	88941402	10	-	27260156	TC32	viability	TTGTCTCCCAGGCATCGTGCTGG	ACTA2	ENSG00000107796	-0.024076846882595926	[760]	[614,612,761,842]	0	hSpCas9	negative selection	9471079
88935253	88935276	10	-	27869803	HPAFII	viability after 27 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	1.0303014535514763	[84]	[111,73,NaN]	8	hSpCas9	negative selection	9538996
88938140	88938163	10	-	27869803	HPAFII	viability after 27 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.6095305280834693	[185]	[32,89,NaN]	-4	hSpCas9	negative selection	9538997
88939497	88939520	10	+	27869803	HPAFII	viability after 27 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.9428011913144727	[359]	[215,486,NaN]	7	hSpCas9	negative selection	9538998
88939541	88939564	10	+	27869803	HPAFII	viability after 27 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.6176471217631447	[244]	[255,148,NaN]	5	hSpCas9	negative selection	9538999
88941221	88941244	10	+	27869803	HPAFII	viability after 27 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.8120514248017466	[278]	[106,63,NaN]	-5	hSpCas9	negative selection	9539000
88941780	88941803	10	+	27869803	HPAFII	viability after 27 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.8368794381995506	[184]	[224,130,NaN]	6	hSpCas9	negative selection	9539001
88935253	88935276	10	-	27869803	HPAFII	viability after 15 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	1.0633694913454572	[84]	[275,137,NaN]	9	hSpCas9	negative selection	9621445
88938140	88938163	10	-	27869803	HPAFII	viability after 15 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.13975682520718347	[185]	[112,223,NaN]	-2	hSpCas9	negative selection	9621446
88939497	88939520	10	+	27869803	HPAFII	viability after 15 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.508845454954828	[359]	[671,474,NaN]	6	hSpCas9	negative selection	9621447
88939541	88939564	10	+	27869803	HPAFII	viability after 15 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.3772402921291589	[244]	[341,341,NaN]	4	hSpCas9	negative selection	9621448
88941221	88941244	10	+	27869803	HPAFII	viability after 15 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.3776160609747668	[278]	[371,142,NaN]	-4	hSpCas9	negative selection	9621449
88941780	88941803	10	+	27869803	HPAFII	viability after 15 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.47290086516751617	[184]	[262,283,NaN]	5	hSpCas9	negative selection	9621450
88935253	88935276	10	-	27869803	ASPC1	viability after 36 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	-0.328583549614752	[309]	[59,91,98]	-3	hSpCas9	negative selection	9703894
88938140	88938163	10	-	27869803	ASPC1	viability after 36 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	0.35270080419452676	[236]	[268,0,72]	3	hSpCas9	negative selection	9703895
88939497	88939520	10	+	27869803	ASPC1	viability after 36 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	-1.3402275313535297	[903]	[230,122,49]	-8	hSpCas9	negative selection	9703896
88939541	88939564	10	+	27869803	ASPC1	viability after 36 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.649876023488438	[577]	[282,566,137]	6	hSpCas9	negative selection	9703897
88941221	88941244	10	+	27869803	ASPC1	viability after 36 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.025087371906824307	[788]	[482,204,170]	0	hSpCas9	negative selection	9703898
88941780	88941803	10	+	27869803	ASPC1	viability after 36 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.08945108114489722	[693]	[241,78,407]	0	hSpCas9	negative selection	9703899
88935253	88935276	10	-	27869803	PATU8988S	viability after 35 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	-0.41830452153983466	[251]	[52,98,NaN]	-4	hSpCas9	negative selection	9786343
88938140	88938163	10	-	27869803	PATU8988S	viability after 35 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	0.4730918534334144	[252]	[114,167,NaN]	5	hSpCas9	negative selection	9786344
88939497	88939520	10	+	27869803	PATU8988S	viability after 35 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.3198662917304913	[681]	[278,406,NaN]	3	hSpCas9	negative selection	9786345
88939541	88939564	10	+	27869803	PATU8988S	viability after 35 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	-0.11375336273359352	[524]	[156,233,NaN]	-1	hSpCas9	negative selection	9786346
88941221	88941244	10	+	27869803	PATU8988S	viability after 35 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.1775242200066297	[605]	[286,264,NaN]	2	hSpCas9	negative selection	9786347
88941780	88941803	10	+	27869803	PATU8988S	viability after 35 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.6004899677858817	[568]	[332,361,NaN]	6	hSpCas9	negative selection	9786348
88935253	88935276	10	-	27869803	PATU8988S	viability after 31 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	0.32399853573477044	[251]	[50,220,NaN]	4	hSpCas9	negative selection	9868792
88938140	88938163	10	-	27869803	PATU8988S	viability after 31 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	0.07466178515280397	[252]	[107,103,NaN]	0	hSpCas9	negative selection	9868793
88939497	88939520	10	+	27869803	PATU8988S	viability after 31 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	0.2413666377257404	[681]	[258,400,NaN]	3	hSpCas9	negative selection	9868794
88939541	88939564	10	+	27869803	PATU8988S	viability after 31 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	-0.2391097952271295	[524]	[212,131,NaN]	-3	hSpCas9	negative selection	9868795
88941221	88941244	10	+	27869803	PATU8988S	viability after 31 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.22607755021815867	[605]	[246,327,NaN]	3	hSpCas9	negative selection	9868796
88941780	88941803	10	+	27869803	PATU8988S	viability after 31 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.49837820652644	[568]	[239,422,NaN]	6	hSpCas9	negative selection	9868797
88935253	88935276	10	-	27869803	HPAFII	viability after 35 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	0.784307017322631	[84]	[59,89,NaN]	5	hSpCas9	negative selection	9951241
88938140	88938163	10	-	27869803	HPAFII	viability after 35 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.11327493821010504	[185]	[71,103,NaN]	0	hSpCas9	negative selection	9951242
88939497	88939520	10	+	27869803	HPAFII	viability after 35 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	1.247299298119166	[359]	[323,554,NaN]	8	hSpCas9	negative selection	9951243
88939541	88939564	10	+	27869803	HPAFII	viability after 35 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.8027121417729044	[244]	[221,209,NaN]	5	hSpCas9	negative selection	9951244
88941221	88941244	10	+	27869803	HPAFII	viability after 35 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.6359310181133189	[278]	[112,65,NaN]	-4	hSpCas9	negative selection	9951245
88941780	88941803	10	+	27869803	HPAFII	viability after 35 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	0.784383959006385	[184]	[189,128,NaN]	5	hSpCas9	negative selection	9951246
88935253	88935276	10	-	27869803	HPAFII	viability after 31 days	AACAGGAATACGATGAAGCCGGG	ACTA2	ENSG00000107796	0.9150316399016759	[84]	[99,78,NaN]	6	hSpCas9	negative selection	10033690
88938140	88938163	10	-	27869803	HPAFII	viability after 31 days	GCTAACAATGTCCTATCAGGGGG	ACTA2	ENSG00000107796	-0.5100463181863241	[185]	[79,65,NaN]	-3	hSpCas9	negative selection	10033691
88939497	88939520	10	+	27869803	HPAFII	viability after 31 days	TGTTGCCTACCGATGAAGGATGG	ACTA2	ENSG00000107796	1.1370012063183557	[359]	[272,630,NaN]	8	hSpCas9	negative selection	10033692
88939541	88939564	10	+	27869803	HPAFII	viability after 31 days	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.023253375322426	[244]	[300,255,NaN]	7	hSpCas9	negative selection	10033693
88941221	88941244	10	+	27869803	HPAFII	viability after 31 days	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-1.1304464640180962	[278]	[71,70,NaN]	-6	hSpCas9	negative selection	10033694
88941780	88941803	10	+	27869803	HPAFII	viability after 31 days	CCTACCAGTTGTGCGTCCAGAGG	ACTA2	ENSG00000107796	1.1540510184381176	[184]	[220,241,NaN]	8	hSpCas9	negative selection	10033695
88948823	88948846	10	+	28162770	P31FUJ	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	-0.07233753222113265	[186]	[208]	0	hSpCas9	negative selection	10106318
88938171	88938194	10	-	28162770	P31FUJ	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.3270256006241229	[385]	[568]	3	hSpCas9	negative selection	10106319
88943838	88943861	10	-	28162770	P31FUJ	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.010754826920111649	[86]	[102]	0	hSpCas9	negative selection	10106320
88941221	88941244	10	+	28162770	P31FUJ	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.09412289001999052	[445]	[490]	-1	hSpCas9	negative selection	10106321
88939604	88939627	10	+	28162770	P31FUJ	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-2.4958366102481726	[95]	[19]	-8	hSpCas9	negative selection	10106322
88939522	88939545	10	+	28162770	P31FUJ	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.5478108853619503	[259]	[208]	-4	hSpCas9	negative selection	10106323
88948883	88948906	10	+	28162770	P31FUJ	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.4665423034541343	[233]	[198]	-4	hSpCas9	negative selection	10106324
88948855	88948878	10	-	28162770	P31FUJ	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	0.29548010171766026	[198]	[286]	3	hSpCas9	negative selection	10106325
88943877	88943900	10	+	28162770	P31FUJ	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.5208867473429539	[222]	[375]	6	hSpCas9	negative selection	10106326
88939541	88939564	10	+	28162770	P31FUJ	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.7963441412451377	[244]	[499]	8	hSpCas9	negative selection	10106327
88948823	88948846	10	+	28162770	TF1	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10275684
88938171	88938194	10	-	28162770	TF1	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	NaN	[NaN]	[346]	1	hSpCas9	negative selection	10275685
88943838	88943861	10	-	28162770	TF1	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10275686
88941221	88941244	10	+	28162770	TF1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	NaN	[NaN]	[361]	1	hSpCas9	negative selection	10275687
88939604	88939627	10	+	28162770	TF1	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10275688
88939522	88939545	10	+	28162770	TF1	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10275689
88948883	88948906	10	+	28162770	TF1	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10275690
88948855	88948878	10	-	28162770	TF1	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10275691
88943877	88943900	10	+	28162770	TF1	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	NaN	[NaN]	[347]	1	hSpCas9	negative selection	10275692
88939541	88939564	10	+	28162770	TF1	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	NaN	[NaN]	[376]	1	hSpCas9	negative selection	10275693
88948823	88948846	10	+	28162770	SKM1	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	1.0597354203581746	[53]	[198]	8	hSpCas9	negative selection	10445050
88938171	88938194	10	-	28162770	SKM1	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.5757578098250027	[62]	[165]	5	hSpCas9	negative selection	10445051
88943838	88943861	10	-	28162770	SKM1	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.017533629784748372	[18]	[33]	0	hSpCas9	negative selection	10445052
88941221	88941244	10	+	28162770	SKM1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.10220295143579028	[126]	[240]	1	hSpCas9	negative selection	10445053
88939604	88939627	10	+	28162770	SKM1	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-2.4386730584705	[45]	[14]	-9	hSpCas9	negative selection	10445054
88939522	88939545	10	+	28162770	SKM1	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.5621345712668947	[75]	[90]	-4	hSpCas9	negative selection	10445055
88948883	88948906	10	+	28162770	SKM1	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.0055311059732289225	[70]	[125]	0	hSpCas9	negative selection	10445056
88948855	88948878	10	-	28162770	SKM1	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-0.024494561920748614	[41]	[72]	0	hSpCas9	negative selection	10445057
88943877	88943900	10	+	28162770	SKM1	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.23328073747918415	[63]	[132]	2	hSpCas9	negative selection	10445058
88939541	88939564	10	+	28162770	SKM1	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.1414724259528806	[59]	[233]	9	hSpCas9	negative selection	10445059
88948823	88948846	10	+	28162770	SKM1	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	1.0597354203581746	[53]	[198]	8	hSpCas9	negative selection	10614416
88938171	88938194	10	-	28162770	SKM1	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.5757578098250027	[62]	[165]	5	hSpCas9	negative selection	10614417
88943838	88943861	10	-	28162770	SKM1	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.017533629784748372	[18]	[33]	0	hSpCas9	negative selection	10614418
88941221	88941244	10	+	28162770	SKM1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.10220295143579028	[126]	[240]	1	hSpCas9	negative selection	10614419
88939604	88939627	10	+	28162770	SKM1	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-2.4386730584705	[45]	[14]	-9	hSpCas9	negative selection	10614420
88939522	88939545	10	+	28162770	SKM1	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.5621345712668947	[75]	[90]	-4	hSpCas9	negative selection	10614421
88948883	88948906	10	+	28162770	SKM1	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.0055311059732289225	[70]	[125]	0	hSpCas9	negative selection	10614422
88948855	88948878	10	-	28162770	SKM1	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-0.024494561920748614	[41]	[72]	0	hSpCas9	negative selection	10614423
88943877	88943900	10	+	28162770	SKM1	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.23328073747918415	[63]	[132]	2	hSpCas9	negative selection	10614424
88939541	88939564	10	+	28162770	SKM1	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.1414724259528806	[59]	[233]	9	hSpCas9	negative selection	10614425
88948823	88948846	10	+	28162770	PL21	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	0.5791078590606421	[242]	[157]	5	hSpCas9	negative selection	10783782
88938171	88938194	10	-	28162770	PL21	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.9777471931528723	[216]	[185]	7	hSpCas9	negative selection	10783783
88943838	88943861	10	-	28162770	PL21	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.5425318119363982	[111]	[70]	5	hSpCas9	negative selection	10783784
88941221	88941244	10	+	28162770	PL21	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.7610966521996869	[403]	[297]	6	hSpCas9	negative selection	10783785
88939604	88939627	10	+	28162770	PL21	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-1.3097214309911172	[130]	[22]	-7	hSpCas9	negative selection	10783786
88939522	88939545	10	+	28162770	PL21	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	0.7766405364622803	[227]	[169]	6	hSpCas9	negative selection	10783787
88948883	88948906	10	+	28162770	PL21	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.10471496703910071	[167]	[67]	0	hSpCas9	negative selection	10783788
88948855	88948878	10	-	28162770	PL21	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-0.5180894170953	[101]	[30]	-4	hSpCas9	negative selection	10783789
88943877	88943900	10	+	28162770	PL21	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	-0.4173907486882666	[223]	[72]	-3	hSpCas9	negative selection	10783790
88939541	88939564	10	+	28162770	PL21	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	-0.12178848039804234	[209]	[83]	-1	hSpCas9	negative selection	10783791
88948823	88948846	10	+	28162770	P31FUJ	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	-0.07233753222113265	[186]	[208]	0	hSpCas9	negative selection	10953148
88938171	88938194	10	-	28162770	P31FUJ	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.3270256006241229	[385]	[568]	3	hSpCas9	negative selection	10953149
88943838	88943861	10	-	28162770	P31FUJ	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.010754826920111649	[86]	[102]	0	hSpCas9	negative selection	10953150
88941221	88941244	10	+	28162770	P31FUJ	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.09412289001999052	[445]	[490]	-1	hSpCas9	negative selection	10953151
88939604	88939627	10	+	28162770	P31FUJ	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-2.4958366102481726	[95]	[19]	-8	hSpCas9	negative selection	10953152
88939522	88939545	10	+	28162770	P31FUJ	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.5478108853619503	[259]	[208]	-4	hSpCas9	negative selection	10953153
88948883	88948906	10	+	28162770	P31FUJ	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.4665423034541343	[233]	[198]	-4	hSpCas9	negative selection	10953154
88948855	88948878	10	-	28162770	P31FUJ	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	0.29548010171766026	[198]	[286]	3	hSpCas9	negative selection	10953155
88943877	88943900	10	+	28162770	P31FUJ	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.5208867473429539	[222]	[375]	6	hSpCas9	negative selection	10953156
88939541	88939564	10	+	28162770	P31FUJ	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.7963441412451377	[244]	[499]	8	hSpCas9	negative selection	10953157
88948823	88948846	10	+	28162770	OCIAML5	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	0.7053100981852596	[87]	[258]	6	hSpCas9	negative selection	11122514
88938171	88938194	10	-	28162770	OCIAML5	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.4912748305392177	[213]	[542]	4	hSpCas9	negative selection	11122515
88943838	88943861	10	-	28162770	OCIAML5	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.46986152402336534	[45]	[114]	4	hSpCas9	negative selection	11122516
88941221	88941244	10	+	28162770	OCIAML5	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.9693361256792399	[218]	[773]	8	hSpCas9	negative selection	11122517
88939604	88939627	10	+	28162770	OCIAML5	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-5.552506289005089	[77]	[2]	-9	hSpCas9	negative selection	11122518
88939522	88939545	10	+	28162770	OCIAML5	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-2.3331932606006136	[133]	[47]	-8	hSpCas9	negative selection	11122519
88948883	88948906	10	+	28162770	OCIAML5	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.2869098422848134	[88]	[195]	2	hSpCas9	negative selection	11122520
88948855	88948878	10	-	28162770	OCIAML5	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	1.0983514002854426	[73]	[285]	8	hSpCas9	negative selection	11122521
88943877	88943900	10	+	28162770	OCIAML5	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.28634745783309773	[143]	[316]	2	hSpCas9	negative selection	11122522
88939541	88939564	10	+	28162770	OCIAML5	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	-0.0069096160940085305	[225]	[405]	0	hSpCas9	negative selection	11122523
88948823	88948846	10	+	28162770	EOL1	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	0.7216515258598838	[342]	[297]	6	hSpCas9	negative selection	11291880
88938171	88938194	10	-	28162770	EOL1	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.8246988432054725	[328]	[306]	7	hSpCas9	negative selection	11291881
88943838	88943861	10	-	28162770	EOL1	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-1.4962953493895148	[165]	[30]	-7	hSpCas9	negative selection	11291882
88941221	88941244	10	+	28162770	EOL1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.8247125039907399	[687]	[641]	7	hSpCas9	negative selection	11291883
88939604	88939627	10	+	28162770	EOL1	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	0.14606290796606153	[234]	[136]	1	hSpCas9	negative selection	11291884
88939522	88939545	10	+	28162770	EOL1	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.6638952978855834	[414]	[137]	-5	hSpCas9	negative selection	11291885
88948883	88948906	10	+	28162770	EOL1	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.6272478652154223	[257]	[87]	-4	hSpCas9	negative selection	11291886
88948855	88948878	10	-	28162770	EOL1	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-1.207902524453115	[170]	[38]	-7	hSpCas9	negative selection	11291887
88943877	88943900	10	+	28162770	EOL1	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	-1.2997170640986841	[256]	[54]	-7	hSpCas9	negative selection	11291888
88939541	88939564	10	+	28162770	EOL1	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.2943560168563807	[242]	[156]	2	hSpCas9	negative selection	11291889
88948823	88948846	10	+	28162770	MOLM13	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	0.8229843403671405	[257]	[329]	6	hSpCas9	negative selection	11461246
88938171	88938194	10	-	28162770	MOLM13	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.214856367868284	[459]	[385]	1	hSpCas9	negative selection	11461247
88943838	88943861	10	-	28162770	MOLM13	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-0.6232585065136168	[146]	[68]	-4	hSpCas9	negative selection	11461248
88941221	88941244	10	+	28162770	MOLM13	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.4905697706853791	[567]	[576]	3	hSpCas9	negative selection	11461249
88939604	88939627	10	+	28162770	MOLM13	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-4.764771375245696	[187]	[4]	-9	hSpCas9	negative selection	11461250
88939522	88939545	10	+	28162770	MOLM13	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-1.2676327957519589	[332]	[99]	-6	hSpCas9	negative selection	11461251
88948883	88948906	10	+	28162770	MOLM13	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-1.5321106184554214	[363]	[90]	-6	hSpCas9	negative selection	11461252
88948855	88948878	10	-	28162770	MOLM13	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	-1.2715193885499563	[196]	[58]	-6	hSpCas9	negative selection	11461253
88943877	88943900	10	+	28162770	MOLM13	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	1.0179768409872754	[320]	[469]	7	hSpCas9	negative selection	11461254
88939541	88939564	10	+	28162770	MOLM13	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.5420711947002816	[397]	[418]	4	hSpCas9	negative selection	11461255
88948823	88948846	10	+	28162770	HEL	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	-0.02605525952426993	[247]	[155]	0	hSpCas9	negative selection	11630612
88938171	88938194	10	-	28162770	HEL	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.5419381912128649	[325]	[303]	4	hSpCas9	negative selection	11630613
88943838	88943861	10	-	28162770	HEL	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-0.896780697959632	[124]	[42]	-5	hSpCas9	negative selection	11630614
88941221	88941244	10	+	28162770	HEL	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.6812864124895759	[516]	[530]	6	hSpCas9	negative selection	11630615
88939604	88939627	10	+	28162770	HEL	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-2.488966847211465	[148]	[16]	-8	hSpCas9	negative selection	11630616
88939522	88939545	10	+	28162770	HEL	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.8436160717801395	[310]	[110]	-5	hSpCas9	negative selection	11630617
88948883	88948906	10	+	28162770	HEL	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.9934489920759723	[257]	[82]	-6	hSpCas9	negative selection	11630618
88948855	88948878	10	-	28162770	HEL	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	0.04383714032132713	[155]	[102]	0	hSpCas9	negative selection	11630619
88943877	88943900	10	+	28162770	HEL	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	1.0221524215484794	[245]	[319]	8	hSpCas9	negative selection	11630620
88939541	88939564	10	+	28162770	HEL	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.6152580955782498	[317]	[311]	5	hSpCas9	negative selection	11630621
88948823	88948846	10	+	28162770	MV411	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	0.7779522674815552	[197]	[285]	7	hSpCas9	negative selection	11799978
88938171	88938194	10	-	28162770	MV411	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.14717342730934635	[282]	[263]	1	hSpCas9	negative selection	11799979
88943838	88943861	10	-	28162770	MV411	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.0993389117936414	[81]	[73]	0	hSpCas9	negative selection	11799980
88941221	88941244	10	+	28162770	MV411	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.8866430962879185	[347]	[541]	7	hSpCas9	negative selection	11799981
88939604	88939627	10	+	28162770	MV411	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-5.121796258882943	[123]	[2]	-9	hSpCas9	negative selection	11799982
88939522	88939545	10	+	28162770	MV411	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.9028050847978373	[272]	[122]	-6	hSpCas9	negative selection	11799983
88948883	88948906	10	+	28162770	MV411	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.2571527056159871	[147]	[148]	2	hSpCas9	negative selection	11799984
88948855	88948878	10	-	28162770	MV411	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	1.493014759540023	[96]	[229]	9	hSpCas9	negative selection	11799985
88943877	88943900	10	+	28162770	MV411	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.11952007586203851	[164]	[150]	1	hSpCas9	negative selection	11799986
88939541	88939564	10	+	28162770	MV411	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	1.5196904866459477	[129]	[313]	9	hSpCas9	negative selection	11799987
88948823	88948846	10	+	28162770	MONOMAC1	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	0.5009346154907887	[134]	[218]	5	hSpCas9	negative selection	11969344
88938171	88938194	10	-	28162770	MONOMAC1	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.8970314773013548	[140]	[300]	8	hSpCas9	negative selection	11969345
88943838	88943861	10	-	28162770	MONOMAC1	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-0.9146371163588287	[73]	[44]	-6	hSpCas9	negative selection	11969346
88941221	88941244	10	+	28162770	MONOMAC1	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.24875188360370926	[283]	[273]	-2	hSpCas9	negative selection	11969347
88939604	88939627	10	+	28162770	MONOMAC1	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-1.7205988031165664	[114]	[39]	-8	hSpCas9	negative selection	11969348
88939522	88939545	10	+	28162770	MONOMAC1	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-1.2811011118480282	[158]	[74]	-7	hSpCas9	negative selection	11969349
88948883	88948906	10	+	28162770	MONOMAC1	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	0.4579731511898591	[133]	[210]	4	hSpCas9	negative selection	11969350
88948855	88948878	10	-	28162770	MONOMAC1	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	1.1359464363368044	[51]	[130]	8	hSpCas9	negative selection	11969351
88943877	88943900	10	+	28162770	MONOMAC1	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.8656989082884089	[134]	[281]	7	hSpCas9	negative selection	11969352
88939541	88939564	10	+	28162770	MONOMAC1	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.049401048243545354	[101]	[120]	0	hSpCas9	negative selection	11969353
88948823	88948846	10	+	28162770	OCIAML2	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	1.0582986405646673	[34]	[403]	8	hSpCas9	negative selection	12138710
88938171	88938194	10	-	28162770	OCIAML2	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	-0.17151161326288467	[50]	[250]	-1	hSpCas9	negative selection	12138711
88943838	88943861	10	-	28162770	OCIAML2	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	0.05862324289270748	[21]	[126]	0	hSpCas9	negative selection	12138712
88941221	88941244	10	+	28162770	OCIAML2	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	-0.04989672029931458	[78]	[422]	0	hSpCas9	negative selection	12138713
88939604	88939627	10	+	28162770	OCIAML2	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-2.122706521821854	[21]	[27]	-8	hSpCas9	negative selection	12138714
88939522	88939545	10	+	28162770	OCIAML2	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.5790059862869531	[37]	[140]	-4	hSpCas9	negative selection	12138715
88948883	88948906	10	+	28162770	OCIAML2	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.907693630851004	[43]	[129]	-6	hSpCas9	negative selection	12138716
88948855	88948878	10	-	28162770	OCIAML2	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	1.278308410590121	[8]	[120]	9	hSpCas9	negative selection	12138717
88943877	88943900	10	+	28162770	OCIAML2	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	1.0067795343241914	[28]	[322]	8	hSpCas9	negative selection	12138718
88939541	88939564	10	+	28162770	OCIAML2	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.4857809062101561	[41]	[325]	5	hSpCas9	negative selection	12138719
88948823	88948846	10	+	28162770	OCIAML3	viability	AATGGATGGGAAAACAGCCCTGG	ACTA2	ENSG00000107796	-0.3245469653309364	[55]	[134]	-3	hSpCas9	negative selection	12308076
88938171	88938194	10	-	28162770	OCIAML3	viability	GTGTGATATTGACATCAGGAAGG	ACTA2	ENSG00000107796	0.9268245229772772	[91]	[527]	7	hSpCas9	negative selection	12308077
88943838	88943861	10	-	28162770	OCIAML3	viability	GCATCCCACCCTGCTCACGGAGG	ACTA2	ENSG00000107796	-0.033292685849684256	[19]	[58]	0	hSpCas9	negative selection	12308078
88941221	88941244	10	+	28162770	OCIAML3	viability	GGCCTCACCAGTAGTAACGAAGG	ACTA2	ENSG00000107796	0.5499221525852047	[111]	[494]	5	hSpCas9	negative selection	12308079
88939604	88939627	10	+	28162770	OCIAML3	viability	GGAGGATGAGGATGCGGCAGTGG	ACTA2	ENSG00000107796	-1.1980789639930238	[37]	[49]	-7	hSpCas9	negative selection	12308080
88939522	88939545	10	+	28162770	OCIAML3	viability	GGAACAGGGTCTCTGGGCAGCGG	ACTA2	ENSG00000107796	-0.8253331864306188	[80]	[137]	-6	hSpCas9	negative selection	12308081
88948883	88948906	10	+	28162770	OCIAML3	viability	AGAGCCATTGTCACACACCAAGG	ACTA2	ENSG00000107796	-0.277748295523493	[50]	[126]	-2	hSpCas9	negative selection	12308082
88948855	88948878	10	-	28162770	OCIAML3	viability	CTGTAAGGCCGGCTTTGCTGGGG	ACTA2	ENSG00000107796	0.05624632064871238	[35]	[112]	0	hSpCas9	negative selection	12308083
88943877	88943900	10	+	28162770	OCIAML3	viability	GAAGCTCATTGTAGAAAGAGTGG	ACTA2	ENSG00000107796	0.16087986183930553	[63]	[215]	1	hSpCas9	negative selection	12308084
88939541	88939564	10	+	28162770	OCIAML3	viability	GCGGAAACGTTCATTTCCGATGG	ACTA2	ENSG00000107796	0.6854157260486637	[61]	[300]	6	hSpCas9	negative selection	12308085