Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:345651
• Symbol:ACTBL2
• Description:actin beta like 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTBL2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
57482590	57482613	5	+	26472758	Jiyoye	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	0.13775534065876838	[316]	[262]	1	hSpCas9	negative selection	2022
57481782	57481805	5	-	26472758	Jiyoye	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.05337677702533894	[160]	[116]	0	hSpCas9	negative selection	2023
57482533	57482556	5	-	26472758	Jiyoye	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	-0.4334040534865937	[581]	[324]	-3	hSpCas9	negative selection	2024
57482479	57482502	5	-	26472758	Jiyoye	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.5822620880639648	[30]	[34]	4	hSpCas9	negative selection	2025
57482383	57482406	5	-	26472758	Jiyoye	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.11426618009004841	[565]	[461]	0	hSpCas9	negative selection	2026
57482374	57482397	5	+	26472758	Jiyoye	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	0.24092603820695957	[146]	[130]	1	hSpCas9	negative selection	2027
57482245	57482268	5	-	26472758	Jiyoye	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	-0.9227455041350194	[361]	[143]	-6	hSpCas9	negative selection	2028
57482174	57482197	5	+	26472758	Jiyoye	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	-0.2805008056638614	[210]	[130]	-2	hSpCas9	negative selection	2029
57482078	57482101	5	+	26472758	Jiyoye	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	-0.07537611827335922	[400]	[286]	0	hSpCas9	negative selection	2030
57482041	57482064	5	-	26472758	Jiyoye	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.9546631768083667	[77]	[113]	6	hSpCas9	negative selection	2031
57482590	57482613	5	+	26472758	KBM7	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.11981670153397428	[1123,917]	[431,445]	-1	hSpCas9	negative selection	193140
57481782	57481805	5	-	26472758	KBM7	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.3021406939952457	[833,740]	[540,379]	3	hSpCas9	negative selection	193141
57482533	57482556	5	-	26472758	KBM7	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	-0.11879598175115369	[2210,1661]	[849,812]	-1	hSpCas9	negative selection	193142
57482479	57482502	5	-	26472758	KBM7	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.7407884535445728	[177,241]	[283,64]	7	hSpCas9	negative selection	193143
57482383	57482406	5	-	26472758	KBM7	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.2814438752576005	[2026,1610]	[1156,920]	3	hSpCas9	negative selection	193144
57482374	57482397	5	+	26472758	KBM7	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	1.049054923330272	[373,319]	[429,252]	9	hSpCas9	negative selection	193145
57482245	57482268	5	-	26472758	KBM7	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	-0.1558928976026286	[1043,1316]	[373,624]	-1	hSpCas9	negative selection	193146
57482174	57482197	5	+	26472758	KBM7	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.3551981828728078	[816,844]	[557,453]	4	hSpCas9	negative selection	193147
57482078	57482101	5	+	26472758	KBM7	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.12830934826927054	[1184,1296]	[684,606]	1	hSpCas9	negative selection	193148
57482041	57482064	5	-	26472758	KBM7	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.7773459675755142	[679,740]	[362,769]	8	hSpCas9	negative selection	193149
57482590	57482613	5	+	26472758	Raji	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	0.9618177395596919	[322]	[145]	8	hSpCas9	negative selection	384258
57481782	57481805	5	-	26472758	Raji	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.1125821485683084	[395]	[84]	-1	hSpCas9	negative selection	384259
57482533	57482556	5	-	26472758	Raji	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	-0.053876604941585526	[746]	[166]	0	hSpCas9	negative selection	384260
57482479	57482502	5	-	26472758	Raji	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.5630630191497894	[34]	[11]	5	hSpCas9	negative selection	384261
57482383	57482406	5	-	26472758	Raji	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.7545944767814765	[755]	[295]	7	hSpCas9	negative selection	384262
57482374	57482397	5	+	26472758	Raji	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	0.3231122264290365	[123]	[35]	3	hSpCas9	negative selection	384263
57482245	57482268	5	-	26472758	Raji	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.040941391998864374	[510]	[121]	0	hSpCas9	negative selection	384264
57482174	57482197	5	+	26472758	Raji	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	-1.1422303546978725	[427]	[44]	-7	hSpCas9	negative selection	384265
57482078	57482101	5	+	26472758	Raji	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.4712821856606426	[602]	[193]	4	hSpCas9	negative selection	384266
57482041	57482064	5	-	26472758	Raji	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.6041048322461513	[308]	[108]	6	hSpCas9	negative selection	384267
57482590	57482613	5	+	26472758	K562	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.46057447676147956	[951]	[583]	-3	hSpCas9	negative selection	575376
57481782	57481805	5	-	26472758	K562	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.9153400904881144	[600]	[268]	-5	hSpCas9	negative selection	575377
57482533	57482556	5	-	26472758	K562	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.5578875514696864	[1470]	[1827]	4	hSpCas9	negative selection	575378
57482479	57482502	5	-	26472758	K562	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-1.8985392261755958	[211]	[47]	-7	hSpCas9	negative selection	575379
57482383	57482406	5	-	26472758	K562	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	-0.46815496557961533	[1387]	[846]	-3	hSpCas9	negative selection	575380
57482374	57482397	5	+	26472758	K562	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	0.9654738033298307	[309]	[510]	7	hSpCas9	negative selection	575381
57482245	57482268	5	-	26472758	K562	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	-0.15905523964573387	[786]	[594]	-1	hSpCas9	negative selection	575382
57482174	57482197	5	+	26472758	K562	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.7257400946998201	[552]	[771]	6	hSpCas9	negative selection	575383
57482078	57482101	5	+	26472758	K562	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.8727449296720771	[862]	[1333]	7	hSpCas9	negative selection	575384
57482041	57482064	5	-	26472758	K562	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.49182006213359997	[432]	[513]	4	hSpCas9	negative selection	575385
57481782	57481805	5	-	26627737	DLD1	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-1.0081678935679834	[347]	[103,42,19]	-7	hSpCas9	negative selection	829105
57481793	57481816	5	+	26627737	DLD1	viability	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.4950216644341525	[187]	[126,103,26]	5	hSpCas9	negative selection	829106
57481937	57481960	5	+	26627737	DLD1	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.5393020969684794	[250]	[157,32,142]	5	hSpCas9	negative selection	829107
57481966	57481989	5	-	26627737	DLD1	viability	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	-0.026240502962947332	[589]	[178,209,158]	0	hSpCas9	negative selection	829108
57482159	57482182	5	-	26627737	DLD1	viability	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.39484564004516426	[578]	[256,217,237]	4	hSpCas9	negative selection	829109
57482580	57482603	5	-	26627737	DLD1	viability	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.6994228606755161	[525]	[138,84,81]	-6	hSpCas9	negative selection	829110
57481782	57481805	5	-	26627737	GBM cells	viability after 5 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.2729795931082233	[124]	[78,82]	4	hSpCas9	negative selection	911420
57481793	57481816	5	+	26627737	GBM cells	viability after 5 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.10054773605533596	[99]	[52,61]	1	hSpCas9	negative selection	911421
57481937	57481960	5	+	26627737	GBM cells	viability after 5 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.2807921473492122	[221]	[135,59]	-4	hSpCas9	negative selection	911422
57481966	57481989	5	-	26627737	GBM cells	viability after 5 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.20546674388613223	[282]	[160,188]	3	hSpCas9	negative selection	911423
57482159	57482182	5	-	26627737	GBM cells	viability after 5 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.533345364921745	[308]	[93,134]	-7	hSpCas9	negative selection	911424
57482580	57482603	5	-	26627737	GBM cells	viability after 5 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.9768280221521688	[188]	[46,55]	-9	hSpCas9	negative selection	911425
57481782	57481805	5	-	26627737	GBM cells	viability after 13 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.6776745179832594	[124]	[113,103]	7	hSpCas9	negative selection	993735
57481793	57481816	5	+	26627737	GBM cells	viability after 13 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.4384964721028326	[99]	[99,51]	5	hSpCas9	negative selection	993736
57481937	57481960	5	+	26627737	GBM cells	viability after 13 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.11608222550692826	[221]	[114,107]	-1	hSpCas9	negative selection	993737
57481966	57481989	5	-	26627737	GBM cells	viability after 13 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	-0.11744713514678591	[282]	[199,93]	-1	hSpCas9	negative selection	993738
57482159	57482182	5	-	26627737	GBM cells	viability after 13 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.4429696152258481	[308]	[92,147]	-5	hSpCas9	negative selection	993739
57482580	57482603	5	-	26627737	GBM cells	viability after 13 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.56869673931106	[188]	[72,65]	-6	hSpCas9	negative selection	993740
57481782	57481805	5	-	26627737	GBM cells	viability after 21 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.3052389679857379	[124]	[85,81]	3	hSpCas9	negative selection	1076050
57481793	57481816	5	+	26627737	GBM cells	viability after 21 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	-0.3897427156369824	[99]	[53,29]	-4	hSpCas9	negative selection	1076051
57481937	57481960	5	+	26627737	GBM cells	viability after 21 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.23962276934458804	[221]	[132,150]	2	hSpCas9	negative selection	1076052
57481966	57481989	5	-	26627737	GBM cells	viability after 21 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	-0.7273359962234894	[282]	[95,89]	-6	hSpCas9	negative selection	1076053
57482159	57482182	5	-	26627737	GBM cells	viability after 21 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.1666920351207113	[308]	[159,139]	-1	hSpCas9	negative selection	1076054
57482580	57482603	5	-	26627737	GBM cells	viability after 21 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-1.191581616376806	[188]	[45,43]	-7	hSpCas9	negative selection	1076055
57481782	57481805	5	-	26627737	RPE1	viability after 9 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.48734170125947407	[292]	[173,69]	3	hSpCas9	negative selection	1158365
57481793	57481816	5	+	26627737	RPE1	viability after 9 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.14961019017336197	[436]	[125,184]	1	hSpCas9	negative selection	1158366
57481937	57481960	5	+	26627737	RPE1	viability after 9 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.19509981354220063	[776]	[236,331]	1	hSpCas9	negative selection	1158367
57481966	57481989	5	-	26627737	RPE1	viability after 9 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	-0.3737890178930925	[1132]	[240,315]	-3	hSpCas9	negative selection	1158368
57482159	57482182	5	-	26627737	RPE1	viability after 9 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.6754465303148197	[531]	[296,225]	4	hSpCas9	negative selection	1158369
57482580	57482603	5	-	26627737	RPE1	viability after 9 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.22070621266889415	[788]	[135,309]	-1	hSpCas9	negative selection	1158370
57481782	57481805	5	-	26627737	RPE1	viability after 12 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.46953888202781646	[292]	[176,36]	3	hSpCas9	negative selection	1240680
57481793	57481816	5	+	26627737	RPE1	viability after 12 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.8437662592515011	[436]	[200,220]	5	hSpCas9	negative selection	1240681
57481937	57481960	5	+	26627737	RPE1	viability after 12 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.5272754222335406	[776]	[295,305]	3	hSpCas9	negative selection	1240682
57481966	57481989	5	-	26627737	RPE1	viability after 12 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	-0.018668140521274523	[1132]	[350,246]	0	hSpCas9	negative selection	1240683
57482159	57482182	5	-	26627737	RPE1	viability after 12 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.5882547407820774	[531]	[227,200]	4	hSpCas9	negative selection	1240684
57482580	57482603	5	-	26627737	RPE1	viability after 12 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.4877975886577038	[788]	[220,377]	3	hSpCas9	negative selection	1240685
57481782	57481805	5	-	26627737	RPE1	viability after 15 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.13823930734136702	[292]	[85,64]	-1	hSpCas9	negative selection	1322995
57481793	57481816	5	+	26627737	RPE1	viability after 15 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.5296373246245005	[436]	[124,229]	3	hSpCas9	negative selection	1322996
57481937	57481960	5	+	26627737	RPE1	viability after 15 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.5425037035192688	[776]	[127,172]	-3	hSpCas9	negative selection	1322997
57481966	57481989	5	-	26627737	RPE1	viability after 15 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	-0.40169640623829417	[1132]	[348,139]	-3	hSpCas9	negative selection	1322998
57482159	57482182	5	-	26627737	RPE1	viability after 15 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.09169556994668848	[531]	[195,125]	0	hSpCas9	negative selection	1322999
57482580	57482603	5	-	26627737	RPE1	viability after 15 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.16645599491300353	[788]	[194,303]	1	hSpCas9	negative selection	1323000
57481782	57481805	5	-	26627737	RPE1	viability after 18 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.06139569231297748	[292]	[112,35]	0	hSpCas9	negative selection	1405310
57481793	57481816	5	+	26627737	RPE1	viability after 18 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.4314487175996959	[436]	[101,219]	2	hSpCas9	negative selection	1405311
57481937	57481960	5	+	26627737	RPE1	viability after 18 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.26411883521705015	[776]	[158,350]	1	hSpCas9	negative selection	1405312
57481966	57481989	5	-	26627737	RPE1	viability after 18 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	-0.98530988157432	[1132]	[181,124]	-6	hSpCas9	negative selection	1405313
57482159	57482182	5	-	26627737	RPE1	viability after 18 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.24839467379432084	[531]	[200,137]	1	hSpCas9	negative selection	1405314
57482580	57482603	5	-	26627737	RPE1	viability after 18 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.22803862641040176	[788]	[216,283]	1	hSpCas9	negative selection	1405315
57481782	57481805	5	-	26627737	HeLa	viability after 8 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.3395405337718347	[116]	[85,2,105]	3	hSpCas9	negative selection	1487625
57481793	57481816	5	+	26627737	HeLa	viability after 8 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	-0.2264751407596145	[297]	[161,118,65]	-2	hSpCas9	negative selection	1487626
57481937	57481960	5	+	26627737	HeLa	viability after 8 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.5305683153889957	[476]	[145,162,123]	-5	hSpCas9	negative selection	1487627
57481966	57481989	5	-	26627737	HeLa	viability after 8 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	1.1045315103104127	[271]	[269,302,197]	8	hSpCas9	negative selection	1487628
57482159	57482182	5	-	26627737	HeLa	viability after 8 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.0003345925333917421	[493]	[326,180,164]	0	hSpCas9	negative selection	1487629
57482580	57482603	5	-	26627737	HeLa	viability after 8 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.029478207541396406	[190]	[118,72,70]	0	hSpCas9	negative selection	1487630
57481782	57481805	5	-	26627737	HeLa	viability after 12 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	1.072426929897047	[116]	[166,53,90]	7	hSpCas9	negative selection	1569940
57481793	57481816	5	+	26627737	HeLa	viability after 12 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.10291736437048843	[297]	[186,97,116]	0	hSpCas9	negative selection	1569941
57481937	57481960	5	+	26627737	HeLa	viability after 12 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.8023721171351665	[476]	[43,179,105]	-6	hSpCas9	negative selection	1569942
57481966	57481989	5	-	26627737	HeLa	viability after 12 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	1.2758300905215352	[271]	[268,351,186]	8	hSpCas9	negative selection	1569943
57482159	57482182	5	-	26627737	HeLa	viability after 12 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.23133546640666056	[493]	[199,168,153]	-2	hSpCas9	negative selection	1569944
57482580	57482603	5	-	26627737	HeLa	viability after 12 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.28991842047637795	[190]	[143,85,61]	2	hSpCas9	negative selection	1569945
57481782	57481805	5	-	26627737	HeLa	viability after 15 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.4797275446416378	[116]	[101,27,68]	4	hSpCas9	negative selection	1652255
57481793	57481816	5	+	26627737	HeLa	viability after 15 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.03342349685312851	[297]	[190,75,102]	0	hSpCas9	negative selection	1652256
57481937	57481960	5	+	26627737	HeLa	viability after 15 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.8580942668357412	[476]	[126,148,39]	-6	hSpCas9	negative selection	1652257
57481966	57481989	5	-	26627737	HeLa	viability after 15 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.7803589077371096	[271]	[242,243,73]	6	hSpCas9	negative selection	1652258
57482159	57482182	5	-	26627737	HeLa	viability after 15 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.22784927581636466	[493]	[168,152,194]	-2	hSpCas9	negative selection	1652259
57482580	57482603	5	-	26627737	HeLa	viability after 15 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	1.026993576193361	[190]	[136,223,110]	7	hSpCas9	negative selection	1652260
57481782	57481805	5	-	26627737	HeLa	viability after 18 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.5216949265284385	[116]	[73,20,68]	4	hSpCas9	negative selection	1734570
57481793	57481816	5	+	26627737	HeLa	viability after 18 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.03760621120079877	[297]	[131,58,102]	0	hSpCas9	negative selection	1734571
57481937	57481960	5	+	26627737	HeLa	viability after 18 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.9039089347495368	[476]	[86,112,39]	-7	hSpCas9	negative selection	1734572
57481966	57481989	5	-	26627737	HeLa	viability after 18 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.8298997870635867	[271]	[171,206,73]	6	hSpCas9	negative selection	1734573
57482159	57482182	5	-	26627737	HeLa	viability after 18 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.2555116655508542	[493]	[109,122,194]	-2	hSpCas9	negative selection	1734574
57482580	57482603	5	-	26627737	HeLa	viability after 18 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	1.0570811074839115	[190]	[93,190,110]	7	hSpCas9	negative selection	1734575
57481782	57481805	5	-	26627737	HCT116	viability after 6 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	1.3095633713186765	[323]	[84,148]	7	hSpCas9	negative selection	1816885
57481793	57481816	5	+	26627737	HCT116	viability after 6 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	-0.7161816763295803	[250]	[43,12]	-4	hSpCas9	negative selection	1816886
57481937	57481960	5	+	26627737	HCT116	viability after 6 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-1.8129206130922915	[371]	[15,16]	-8	hSpCas9	negative selection	1816887
57481966	57481989	5	-	26627737	HCT116	viability after 6 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	1.3055468224933815	[634]	[559,73]	7	hSpCas9	negative selection	1816888
57482159	57482182	5	-	26627737	HCT116	viability after 6 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.32966509696108887	[388]	[159,30]	1	hSpCas9	negative selection	1816889
57482580	57482603	5	-	26627737	HCT116	viability after 6 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.8089658950847336	[483]	[44,181]	4	hSpCas9	negative selection	1816890
57481782	57481805	5	-	26627737	HCT116	viability after 8 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.703715295150751	[252]	[38,134,81]	-7	hSpCas9	negative selection	1899200
57481793	57481816	5	+	26627737	HCT116	viability after 8 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.16257740005459265	[190]	[134,124,93]	2	hSpCas9	negative selection	1899201
57481937	57481960	5	+	26627737	HCT116	viability after 8 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.7750423470526246	[440]	[184,117,123]	-7	hSpCas9	negative selection	1899202
57481966	57481989	5	-	26627737	HCT116	viability after 8 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.1161443349520917	[364]	[139,247,263]	1	hSpCas9	negative selection	1899203
57482159	57482182	5	-	26627737	HCT116	viability after 8 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.27692268561108413	[376]	[174,214,124]	-3	hSpCas9	negative selection	1899204
57482580	57482603	5	-	26627737	HCT116	viability after 8 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.2736955572223868	[203]	[76,135,65]	-3	hSpCas9	negative selection	1899205
57481782	57481805	5	-	26627737	HCT116	viability after 9 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-1.0512337290164404	[323]	[5,69]	-6	hSpCas9	negative selection	1981515
57481793	57481816	5	+	26627737	HCT116	viability after 9 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	-0.26781195084440745	[250]	[34,71]	-2	hSpCas9	negative selection	1981516
57481937	57481960	5	+	26627737	HCT116	viability after 9 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.15637763461648735	[371]	[41,164]	1	hSpCas9	negative selection	1981517
57481966	57481989	5	-	26627737	HCT116	viability after 9 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.3042836116357256	[634]	[243,181]	2	hSpCas9	negative selection	1981518
57482159	57482182	5	-	26627737	HCT116	viability after 9 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	1.191860552100015	[388]	[224,246]	7	hSpCas9	negative selection	1981519
57482580	57482603	5	-	26627737	HCT116	viability after 9 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.8706958955498425	[483]	[94,347]	6	hSpCas9	negative selection	1981520
57481782	57481805	5	-	26627737	HCT116	viability after 12 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-1.022085878106765	[252]	[44,56,95]	-8	hSpCas9	negative selection	2063830
57481793	57481816	5	+	26627737	HCT116	viability after 12 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.4224887212683782	[190]	[71,213,124]	4	hSpCas9	negative selection	2063831
57481937	57481960	5	+	26627737	HCT116	viability after 12 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-1.055072961631013	[440]	[86,120,128]	-8	hSpCas9	negative selection	2063832
57481966	57481989	5	-	26627737	HCT116	viability after 12 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.3188704730176509	[364]	[190,237,292]	3	hSpCas9	negative selection	2063833
57482159	57482182	5	-	26627737	HCT116	viability after 12 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.06234465464762173	[376]	[175,316,132]	0	hSpCas9	negative selection	2063834
57482580	57482603	5	-	26627737	HCT116	viability after 12 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.3849746973079451	[203]	[118,146,155]	4	hSpCas9	negative selection	2063835
57481782	57481805	5	-	26627737	HCT116	viability after 15 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.8233615647798862	[252]	[43,140,56]	-7	hSpCas9	negative selection	2146145
57481793	57481816	5	+	26627737	HCT116	viability after 15 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.417907855917164	[190]	[106,195,131]	4	hSpCas9	negative selection	2146146
57481937	57481960	5	+	26627737	HCT116	viability after 15 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.823520192066667	[440]	[95,51,273]	-7	hSpCas9	negative selection	2146147
57481966	57481989	5	-	26627737	HCT116	viability after 15 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.4879550813119107	[364]	[156,308,397]	4	hSpCas9	negative selection	2146148
57482159	57482182	5	-	26627737	HCT116	viability after 15 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.2776907813208275	[376]	[241,245,56]	-3	hSpCas9	negative selection	2146149
57482580	57482603	5	-	26627737	HCT116	viability after 15 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.4723992540218413	[203]	[207,108,175]	4	hSpCas9	negative selection	2146150
57481782	57481805	5	-	26627737	HCT116	viability after 18 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.5217431897305655	[252]	[34,67,156]	-5	hSpCas9	negative selection	2228460
57481793	57481816	5	+	26627737	HCT116	viability after 18 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	-0.006693765063716883	[190]	[82,118,70]	0	hSpCas9	negative selection	2228461
57481937	57481960	5	+	26627737	HCT116	viability after 18 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.8649693467667808	[440]	[55,117,179]	-7	hSpCas9	negative selection	2228462
57481966	57481989	5	-	26627737	HCT116	viability after 18 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	-0.18455694400479306	[364]	[102,157,206]	-2	hSpCas9	negative selection	2228463
57482159	57482182	5	-	26627737	HCT116	viability after 18 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.11737730228750137	[376]	[131,319,129]	1	hSpCas9	negative selection	2228464
57482580	57482603	5	-	26627737	HCT116	viability after 18 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.060862721591469104	[203]	[159,118,24]	0	hSpCas9	negative selection	2228465
57482580	57482603	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.7317052810287644	[2,2]	[1,0]	-8	hSpCas9	positive selection	2968682
57482402	57482425	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGCTCATCTGGTGCCACACGG	ACTBL2	ENSG00000169067	0.03642771366002159	[4,4]	[4,2]	0	hSpCas9	positive selection	2968683
57482383	57482406	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.055259811139371603	[3,3]	[3,3]	1	hSpCas9	positive selection	2968684
57482264	57482287	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCCCTCTATGCCTCAGGACGG	ACTBL2	ENSG00000169067	0.6569429993907536	[3,3]	[5,5]	9	hSpCas9	positive selection	2968685
57482580	57482603	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.12190508315789184	[2,2]	[1,0]	-2	hSpCas9	positive selection	3036540
57482402	57482425	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGCTCATCTGGTGCCACACGG	ACTBL2	ENSG00000169067	0.4609068080257841	[4,4]	[4,4]	7	hSpCas9	positive selection	3036541
57482383	57482406	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	-0.43561327374280934	[3,3]	[3,0]	-6	hSpCas9	positive selection	3036542
57482264	57482287	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCCCTCTATGCCTCAGGACGG	ACTBL2	ENSG00000169067	-0.5490227684132144	[3,3]	[3,0]	-7	hSpCas9	positive selection	3036543
57481700	57481723		-	24336571	A375	resistance to PLX after 7 days	AGATCATAGCTCCCCCAGAGCGG	ACTBL2	ENSG00000169067	-0.0797247335199307	[2,4]	[2,3]	-2	hSpCas9	positive selection	3159650
57482170	57482193		-	24336571	A375	resistance to PLX after 7 days	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	-0.01954256661388898	[26,23]	[20,28]	0	hSpCas9	positive selection	3159659
57482572	57482595		-	24336571	A375	resistance to PLX after 7 days	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	-0.2703649044243	[18,18]	[13,16]	-7	hSpCas9	positive selection	3159676
57482588	57482611		+	24336571	A375	resistance to PLX after 7 days	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.042685750659395616	[4,5]	[4,4]	-1	hSpCas9	positive selection	3159682
57481700	57481723		-	24336571	A375	resistance to PLX after 14 days	AGATCATAGCTCCCCCAGAGCGG	ACTBL2	ENSG00000169067	0.5683761213659089	[1,3]	[1,1]	5	hSpCas9	positive selection	3217443
57482170	57482193		-	24336571	A375	resistance to PLX after 14 days	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.05336608459191994	[29,29]	[12,14]	0	hSpCas9	positive selection	3217452
57482572	57482595		-	24336571	A375	resistance to PLX after 14 days	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	-1.0904729958502193	[20,18]	[3,3]	-9	hSpCas9	positive selection	3217469
57482588	57482611		+	24336571	A375	resistance to PLX after 14 days	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.32886758128356464	[5,4]	[1,1]	-4	hSpCas9	positive selection	3217475
57481700	57481723		-	24336571	A375	viability after 7 days	AGATCATAGCTCCCCCAGAGCGG	ACTBL2	ENSG00000169067	-0.3794469939531535	[5]	[2,4]	-5	hSpCas9	negative selection	3275236
57482170	57482193		-	24336571	A375	viability after 7 days	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.16123933151033676	[23]	[26,23]	2	hSpCas9	negative selection	3275245
57482572	57482595		-	24336571	A375	viability after 7 days	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.8030082751054788	[10]	[18,18]	9	hSpCas9	negative selection	3275262
57482588	57482611		+	24336571	A375	viability after 7 days	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.2873502795605556	[6]	[4,5]	-4	hSpCas9	negative selection	3275268
57481700	57481723		-	24336571	A375	viability after 14 days	AGATCATAGCTCCCCCAGAGCGG	ACTBL2	ENSG00000169067	-0.6194331799564874	[5]	[1,3]	-6	hSpCas9	negative selection	3333029
57482170	57482193		-	24336571	A375	viability after 14 days	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.40246759204631266	[23]	[29,29]	5	hSpCas9	negative selection	3333038
57482572	57482595		-	24336571	A375	viability after 14 days	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.8906085682769247	[10]	[20,18]	9	hSpCas9	negative selection	3333055
57482588	57482611		+	24336571	A375	viability after 14 days	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.1875598731602206	[6]	[5,4]	-2	hSpCas9	negative selection	3333061
57482572	57482595	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	1.5579749090794068	[45,57]	[0,0]	6	hSpCas9	positive selection	3335391
57482162	57482185	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.36322177079315987	[109,127]	[0,0]	2	hSpCas9	positive selection	3335392
57482170	57482193	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	-2.1424089707274723	[669,680]	[0,0]	-9	hSpCas9	positive selection	3335393
57482588	57482611	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-1.5305763479455965	[441,441]	[0,0]	-8	hSpCas9	positive selection	3354640
57481977	57482000	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.3201026165899134	[190,190]	[0,0]	-2	hSpCas9	positive selection	3354641
57481937	57481960	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.17517717009196343	[270,270]	[1,1]	0	hSpCas9	positive selection	3354642
57482580	57482603	5	-	26780180	HT29	viability (Avana library 4 designs)	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	2.27575837659861	[]	[]	7	hSpCas9	negative selection	3404630
57482401	57482424	5	+	26780180	HT29	viability (Avana library 4 designs)	GATGCTCATCTGGTGCCACACGG	ACTBL2	ENSG00000169067	0.62290650992458	[]	[]	2	hSpCas9	negative selection	3404631
57482383	57482406	5	-	26780180	HT29	viability (Avana library 4 designs)	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.732771113863811	[]	[]	3	hSpCas9	negative selection	3404632
57482264	57482287	5	-	26780180	HT29	viability (Avana library 4 designs)	TGTCCCTCTATGCCTCAGGACGG	ACTBL2	ENSG00000169067	-0.472882135618837	[]	[]	-7	hSpCas9	negative selection	3404633
57482383	57482406	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	-5.98162535576143	[]	[]	-6	hSpCas9	negative selection	3476261
57482401	57482424	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGCTCATCTGGTGCCACACGG	ACTBL2	ENSG00000169067	5.42525483204144	[]	[]	8	hSpCas9	negative selection	3476262
57482580	57482603	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	3.08673068781569	[]	[]	5	hSpCas9	negative selection	3476263
57482264	57482287	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCCCTCTATGCCTCAGGACGG	ACTBL2	ENSG00000169067	2.85129871473352	[]	[]	4	hSpCas9	negative selection	3476264
57482563	57482586	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCATGCCTACCATAACGCCCTGG	ACTBL2	ENSG00000169067	-6.7630429481566	[]	[]	-6	hSpCas9	negative selection	3476265
57482605	57482628	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGAGGGGAACACAGCCCGGGGG	ACTBL2	ENSG00000169067	-2.19488479872332	[]	[]	-3	hSpCas9	negative selection	3476266
57482383	57482406	5	-	26780180	A375	viability (Avana lentiGuide)	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	-6.61108811279025	[]	[]	-9	hSpCas9	negative selection	3584920
57482401	57482424	5	+	26780180	A375	viability (Avana lentiGuide)	GATGCTCATCTGGTGCCACACGG	ACTBL2	ENSG00000169067	-1.05415148218984	[]	[]	-2	hSpCas9	negative selection	3584921
57482580	57482603	5	-	26780180	A375	viability (Avana lentiGuide)	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.723013938935973	[]	[]	-1	hSpCas9	negative selection	3584922
57482264	57482287	5	-	26780180	A375	viability (Avana lentiGuide)	TGTCCCTCTATGCCTCAGGACGG	ACTBL2	ENSG00000169067	-0.867585077377356	[]	[]	-1	hSpCas9	negative selection	3584923
57482563	57482586	5	+	26780180	A375	viability (Avana lentiGuide)	CCATGCCTACCATAACGCCCTGG	ACTBL2	ENSG00000169067	-0.213828643414979	[]	[]	0	hSpCas9	negative selection	3584924
57482605	57482628	5	+	26780180	A375	viability (Avana lentiGuide)	TGGAGGGGAACACAGCCCGGGGG	ACTBL2	ENSG00000169067	9.85421578407976	[]	[]	6	hSpCas9	negative selection	3584925
57482383	57482406	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	-0.15680367140788243	[4]	[2,3]	-3	hSpCas9	positive selection	3693579
57482401	57482424	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGCTCATCTGGTGCCACACGG	ACTBL2	ENSG00000169067	0.28635886394212196	[6]	[7,7]	8	hSpCas9	positive selection	3693580
57482580	57482603	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.0726066397783101	[4]	[4,4]	1	hSpCas9	positive selection	3693581
57482264	57482287	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCCCTCTATGCCTCAGGACGG	ACTBL2	ENSG00000169067	0.30324552340949645	[5]	[7,5]	8	hSpCas9	positive selection	3693582
57482563	57482586	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATGCCTACCATAACGCCCTGG	ACTBL2	ENSG00000169067	-0.5820195886485443	[4]	[2,2]	-7	hSpCas9	positive selection	3693583
57482605	57482628	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGAGGGGAACACAGCCCGGGGG	ACTBL2	ENSG00000169067	-0.2181617541073697	[4]	[3,2]	-3	hSpCas9	positive selection	3693584
57482383	57482406	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.09502179781083867	[5]	[4,5]	2	hSpCas9	positive selection	3802186
57482401	57482424	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGCTCATCTGGTGCCACACGG	ACTBL2	ENSG00000169067	-0.07690007597881685	[6]	[4,5]	-1	hSpCas9	positive selection	3802187
57482580	57482603	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.2656583081565024	[4]	[2,3]	-4	hSpCas9	positive selection	3802188
57482264	57482287	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCCCTCTATGCCTCAGGACGG	ACTBL2	ENSG00000169067	0.17461178812729347	[5]	[4,5]	4	hSpCas9	positive selection	3802189
57482563	57482586	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATGCCTACCATAACGCCCTGG	ACTBL2	ENSG00000169067	0.036018164630140556	[5]	[4,5]	0	hSpCas9	positive selection	3802190
57482605	57482628	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGAGGGGAACACAGCCCGGGGG	ACTBL2	ENSG00000169067	-1.743701271369026	[4]	[0,0]	-9	hSpCas9	positive selection	3802191
57482170	57482193	5	-	26780180	A375	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	-0.0652161691180799	[]	[]	-2	hSpCas9	negative selection	3910796
57481977	57482000	5	+	26780180	A375	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.287329505617215	[]	[]	0	hSpCas9	negative selection	3910797
57482572	57482595	5	-	26780180	A375	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.743271801637825	[]	[]	2	hSpCas9	negative selection	3910798
57482588	57482611	5	+	26780180	A375	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	1.04717794571955	[]	[]	5	hSpCas9	negative selection	3910799
57481937	57481960	5	+	26780180	A375	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	1.40288160583427	[]	[]	7	hSpCas9	negative selection	3910800
57482162	57482185	5	+	26780180	A375	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	-0.223541463334993	[]	[]	-6	hSpCas9	negative selection	3910801
57482170	57482193	5	-	26780180	HT29	viability (GeCKOv2 library)	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	-0.393445901625972	[]	[]	-8	hSpCas9	negative selection	4018762
57481977	57482000	5	+	26780180	HT29	viability (GeCKOv2 library)	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.905391616100808	[]	[]	4	hSpCas9	negative selection	4018763
57482572	57482595	5	-	26780180	HT29	viability (GeCKOv2 library)	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	1.04930447324365	[]	[]	5	hSpCas9	negative selection	4018764
57482588	57482611	5	+	26780180	HT29	viability (GeCKOv2 library)	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	0.23203272830358	[]	[]	0	hSpCas9	negative selection	4018765
57481937	57481960	5	+	26780180	HT29	viability (GeCKOv2 library)	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	1.08830985791259	[]	[]	5	hSpCas9	negative selection	4018766
57482162	57482185	5	+	26780180	HT29	viability (GeCKOv2 library)	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.0596446503688188	[]	[]	0	hSpCas9	negative selection	4018767
57481700	57481723	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGATCATAGCTCCCCCAGAGCGG	ACTBL2	ENSG00000169067	-0.2738063478109396	[2]	[1,0]	-6	hSpCas9	positive selection	4187548
57482170	57482193	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.30387416773870035	[4]	[3,3]	7	hSpCas9	positive selection	4187559
57482572	57482595	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.04937585753807955	[3]	[3,1]	1	hSpCas9	positive selection	4187581
57482588	57482611	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.3626600937833244	[2]	[1,0]	-7	hSpCas9	positive selection	4187592
57481700	57481723	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGATCATAGCTCCCCCAGAGCGG	ACTBL2	ENSG00000169067	0.00918238249411174	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4251570
57482170	57482193	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.4124468446760294	[4]	[5,4,3,0]	3	hSpCas9	positive selection	4251581
57482572	57482595	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	-0.42875830451652547	[3]	[0,0,0,0]	-6	hSpCas9	positive selection	4251603
57482588	57482611	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	0.8914276204342904	[3]	[0,2,1,4]	6	hSpCas9	positive selection	4251614
57482572	57482595	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	-0.16115078355465612	[2]	[1,1]	-3	hSpCas9	positive selection	4254308
57482162	57482185	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.7869661435915499	[3]	[3,5]	9	hSpCas9	positive selection	4254309
57482170	57482193	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.4011551550714386	[4]	[5,4]	7	hSpCas9	positive selection	4254310
57482588	57482611	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	0.3231440206367012	[4]	[4,5]	6	hSpCas9	positive selection	4318591
57481977	57482000	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.21380683919637772	[3]	[3,2]	4	hSpCas9	positive selection	4318592
57481937	57481960	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.3218068666339103	[3]	[3,3]	6	hSpCas9	positive selection	4318593
57481991	57482013	5	-	27760321	OCIAML3	viability	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.7445651252145389	[745,749]	[802,1218]	8	hSpCas9	negative selection	4375851
57482170	57482192	5	-	27760321	OCIAML3	viability	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.3536994501129085	[799,632]	[566,899]	4	hSpCas9	negative selection	4375852
57482256	57482278	5	-	27760321	OCIAML3	viability	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.974107372096979	[773,727]	[1066,1268]	9	hSpCas9	negative selection	4375853
57482479	57482501	5	-	27760321	OCIAML3	viability	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.3237380903960025	[455,396]	[241,296]	-3	hSpCas9	negative selection	4375854
57482581	57482603	5	-	27760321	OCIAML3	viability	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	-0.29914753901913693	[688,578]	[377,431]	-3	hSpCas9	negative selection	4375855
57481991	57482013	5	-	27760321	OCIAML2	viability	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	-0.13708392423848004	[745,749]	[483,641]	-2	hSpCas9	negative selection	4459314
57482170	57482192	5	-	27760321	OCIAML2	viability	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.7448128200497721	[799,632]	[893,1058]	8	hSpCas9	negative selection	4459315
57482256	57482278	5	-	27760321	OCIAML2	viability	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	-0.1432337789282394	[773,727]	[430,707]	-2	hSpCas9	negative selection	4459316
57482479	57482501	5	-	27760321	OCIAML2	viability	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.2592864181707989	[455,396]	[265,315]	-3	hSpCas9	negative selection	4459317
57482581	57482603	5	-	27760321	OCIAML2	viability	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.09505146330867886	[688,578]	[483,626]	1	hSpCas9	negative selection	4459318
57481991	57482013	5	-	27760321	MV411	viability	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	-0.2656855180750799	[745,749]	[437,372]	-2	hSpCas9	negative selection	4542777
57482170	57482192	5	-	27760321	MV411	viability	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.9415412499092932	[799,632]	[879,935]	7	hSpCas9	negative selection	4542778
57482256	57482278	5	-	27760321	MV411	viability	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.5898926159733521	[773,727]	[863,569]	4	hSpCas9	negative selection	4542779
57482479	57482501	5	-	27760321	MV411	viability	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.2518847630645838	[455,396]	[496,89]	1	hSpCas9	negative selection	4542780
57482581	57482603	5	-	27760321	MV411	viability	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.09168433814367938	[688,578]	[585,230]	0	hSpCas9	negative selection	4542781
57481991	57482013	5	-	27760321	HL60	viability	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	-0.26225542502467314	[745,749]	[535,484]	-3	hSpCas9	negative selection	4626240
57482170	57482192	5	-	27760321	HL60	viability	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.4638821366734611	[799,632]	[791,812]	5	hSpCas9	negative selection	4626241
57482256	57482278	5	-	27760321	HL60	viability	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	-0.040707661584018284	[773,727]	[608,583]	0	hSpCas9	negative selection	4626242
57482479	57482501	5	-	27760321	HL60	viability	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.46033908920463	[455,396]	[272,230]	-5	hSpCas9	negative selection	4626243
57482581	57482603	5	-	27760321	HL60	viability	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.7712669477438738	[688,578]	[649,1124]	8	hSpCas9	negative selection	4626244
57481991	57482013	5	-	27760321	HT1080	viability	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.2285522696926352	[749,584]	[301,321]	1	hSpCas9	negative selection	4709703
57482170	57482192	5	-	27760321	HT1080	viability	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.8508700798689409	[632,493]	[359,453]	4	hSpCas9	negative selection	4709704
57482256	57482278	5	-	27760321	HT1080	viability	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.43448750768973965	[727,567]	[250,455]	2	hSpCas9	negative selection	4709705
57482479	57482501	5	-	27760321	HT1080	viability	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.14709226475692228	[396,309]	[217,87]	0	hSpCas9	negative selection	4709706
57482581	57482603	5	-	27760321	HT1080	viability	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.8190476160185786	[578,451]	[273,458]	4	hSpCas9	negative selection	4709707
57481991	57482013	5	-	27760321	HT29	viability after 7 days	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.3504919318351447	[749,584]	[911,1217,1123]	5	hSpCas9	negative selection	4793166
57482170	57482192	5	-	27760321	HT29	viability after 7 days	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.46349427772162033	[632,493]	[1135,909,969]	7	hSpCas9	negative selection	4793167
57482256	57482278	5	-	27760321	HT29	viability after 7 days	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.430727134431375	[727,567]	[1477,1136,812]	6	hSpCas9	negative selection	4793168
57482479	57482501	5	-	27760321	HT29	viability after 7 days	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.6652826112226785	[396,309]	[317,358,189]	-7	hSpCas9	negative selection	4793169
57482581	57482603	5	-	27760321	HT29	viability after 7 days	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	-0.5093118008029326	[578,451]	[362,468,546]	-6	hSpCas9	negative selection	4793170
57481991	57482013	5	-	27760321	HT29	viability after 25 days	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.675421331946666	[749,584]	[864,1239,1610]	7	hSpCas9	negative selection	4876629
57482170	57482192	5	-	27760321	HT29	viability after 25 days	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.8217012507365192	[632,493]	[899,992,1580]	8	hSpCas9	negative selection	4876630
57482256	57482278	5	-	27760321	HT29	viability after 25 days	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.3800064768626341	[727,567]	[963,1104,803]	4	hSpCas9	negative selection	4876631
57482479	57482501	5	-	27760321	HT29	viability after 25 days	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-1.0859260183924626	[396,309]	[199,231,131]	-7	hSpCas9	negative selection	4876632
57482581	57482603	5	-	27760321	HT29	viability after 25 days	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.36477597634813785	[578,451]	[568,843,886]	4	hSpCas9	negative selection	4876633
57481991	57482013	5	-	27760321	HT29	viability after 22 days	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.8124081864528474	[749,584]	[1558,1012,1488]	8	hSpCas9	negative selection	4960092
57482170	57482192	5	-	27760321	HT29	viability after 22 days	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.8829784488856413	[632,493]	[1156,955,1494]	8	hSpCas9	negative selection	4960093
57482256	57482278	5	-	27760321	HT29	viability after 22 days	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.1093151980134992	[727,567]	[810,815,796]	1	hSpCas9	negative selection	4960094
57482479	57482501	5	-	27760321	HT29	viability after 22 days	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.2601439601395677	[396,309]	[175,530,320]	-3	hSpCas9	negative selection	4960095
57482581	57482603	5	-	27760321	HT29	viability after 22 days	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.3056431468427633	[578,451]	[639,868,702]	3	hSpCas9	negative selection	4960096
57481991	57482013	5	-	27760321	HT29	viability after 19 days	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.45401487168766863	[749,584]	[1145,903,1094]	4	hSpCas9	negative selection	5043555
57482170	57482192	5	-	27760321	HT29	viability after 19 days	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	1.0597762189540356	[632,493]	[1163,976,1849]	9	hSpCas9	negative selection	5043556
57482256	57482278	5	-	27760321	HT29	viability after 19 days	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.19707550112062022	[727,567]	[766,1097,680]	1	hSpCas9	negative selection	5043557
57482479	57482501	5	-	27760321	HT29	viability after 19 days	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.41012182556463933	[396,309]	[523,332,86]	-4	hSpCas9	negative selection	5043558
57482581	57482603	5	-	27760321	HT29	viability after 19 days	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.43571076480237103	[578,451]	[752,698,929]	4	hSpCas9	negative selection	5043559
57481991	57482013	5	-	27760321	HT29	viability after 16 days	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.31941394686802793	[749,584]	[928,1050,811]	3	hSpCas9	negative selection	5127018
57482170	57482192	5	-	27760321	HT29	viability after 16 days	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.9054675687947488	[632,493]	[1048,1222,1256]	9	hSpCas9	negative selection	5127019
57482256	57482278	5	-	27760321	HT29	viability after 16 days	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.43039430137529	[727,567]	[1116,899,928]	5	hSpCas9	negative selection	5127020
57482479	57482501	5	-	27760321	HT29	viability after 16 days	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.1752650446520515	[396,309]	[363,389,296]	-2	hSpCas9	negative selection	5127021
57482581	57482603	5	-	27760321	HT29	viability after 16 days	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.3680403541238093	[578,451]	[720,542,971]	4	hSpCas9	negative selection	5127022
57481991	57482013	5	-	27760321	HT29	viability after 13 days	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.4976744717461594	[749,584]	[1544,815,927]	6	hSpCas9	negative selection	5210481
57482170	57482192	5	-	27760321	HT29	viability after 13 days	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.7437017797306132	[632,493]	[1266,882,1130]	8	hSpCas9	negative selection	5210482
57482256	57482278	5	-	27760321	HT29	viability after 13 days	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.006390413676983786	[727,567]	[544,1006,715]	0	hSpCas9	negative selection	5210483
57482479	57482501	5	-	27760321	HT29	viability after 13 days	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.41503721925756304	[396,309]	[189,442,290]	-5	hSpCas9	negative selection	5210484
57482581	57482603	5	-	27760321	HT29	viability after 13 days	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.043424377440646755	[578,451]	[475,753,618]	0	hSpCas9	negative selection	5210485
57481991	57482013	5	-	27760321	HT29	viability after 10 days	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.471547136527271	[749,584]	[1147,1108,1206]	6	hSpCas9	negative selection	5293944
57482170	57482192	5	-	27760321	HT29	viability after 10 days	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.690095555274682	[632,493]	[1242,1183,982]	8	hSpCas9	negative selection	5293945
57482256	57482278	5	-	27760321	HT29	viability after 10 days	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.05580397127273762	[727,567]	[789,768,958]	0	hSpCas9	negative selection	5293946
57482479	57482501	5	-	27760321	HT29	viability after 10 days	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.47182387276235105	[396,309]	[275,422,259]	-5	hSpCas9	negative selection	5293947
57482581	57482603	5	-	27760321	HT29	viability after 10 days	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.2653312796187798	[578,451]	[603,1256,479]	3	hSpCas9	negative selection	5293948
57481991	57482013	5	-	27760321	MOLM13	viability	CGCATCCTCCTCACCGGAACGG	ACTBL2	ENSG00000169067	0.3485493287065644	[745,749]	[441,621]	2	hSpCas9	negative selection	5377407
57482170	57482192	5	-	27760321	MOLM13	viability	CCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.9691601127520415	[799,632]	[652,899]	7	hSpCas9	negative selection	5377408
57482256	57482278	5	-	27760321	MOLM13	viability	ATGCCTCAGGACGGACCACAGG	ACTBL2	ENSG00000169067	0.6284873050792849	[773,727]	[533,758]	4	hSpCas9	negative selection	5377409
57482479	57482501	5	-	27760321	MOLM13	viability	TATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.08636036555589416	[455,396]	[249,258]	0	hSpCas9	negative selection	5377410
57482581	57482603	5	-	27760321	MOLM13	viability	ATAGGGCGTCCTCGACACCAGG	ACTBL2	ENSG00000169067	0.10336403486524748	[688,578]	[472,305]	0	hSpCas9	negative selection	5377411
57482371	57482394	5	+	27661255	K562	viability	GGTTCAGGGGTGCCTCGGTGAGG	ACTBL2	ENSG00000169067	0.07860748434725667	[961,1019]	[928,754]	2	dCas9-KRAB	negative selection	5460708
57482422	57482445	5	+	27661255	K562	viability	GGAGCTCATTGTAGAATGTGTGG	ACTBL2	ENSG00000169067	-0.10088083877972562	[871,970]	[724,650]	-4	dCas9-KRAB	negative selection	5460709
57482585	57482608	5	+	27661255	K562	viability	GTGTCGAGGACGCCCTATCATGG	ACTBL2	ENSG00000169067	0.021976373650943737	[1084,1001]	[873,824]	0	dCas9-KRAB	negative selection	5460710
57482590	57482613	5	+	27661255	K562	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	0.08687364335734638	[554,509]	[486,422]	3	dCas9-KRAB	negative selection	5460711
57482795	57482818	5	+	27661255	K562	viability	GAAATGCTTTCAGACACGGGAGG	ACTBL2	ENSG00000169067	0.262397473706262	[778,948]	[893,765]	8	dCas9-KRAB	negative selection	5460712
57482383	57482406	5	-	27661255	K562	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.1704618519063008	[1751,1961]	[1807,1544]	6	dCas9-KRAB	negative selection	5460713
57482447	57482470	5	-	27661255	K562	viability	GGGACGATATGGAAAAGATCTGG	ACTBL2	ENSG00000169067	0.026959040624643826	[1530,1753]	[1461,1223]	0	dCas9-KRAB	negative selection	5460714
57482533	57482556	5	-	27661255	K562	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	-0.06677380618215656	[1665,1657]	[1420,1136]	-3	dCas9-KRAB	negative selection	5460715
57482572	57482595	5	-	27260156	BXPC3	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.12263695104612471	[253]	[232,306,267,359]	2	hSpCas9	negative selection	5526768
57482162	57482185	5	+	27260156	BXPC3	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.22866231595363556	[517]	[624,572,657,689]	5	hSpCas9	negative selection	5526769
57482170	57482193	5	-	27260156	BXPC3	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.46923998135656375	[1518]	[1883,2087,2414,2470]	8	hSpCas9	negative selection	5526770
57482588	57482611	5	+	27260156	BXPC3	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.23921753460858453	[1906]	[1666,1580,1654,1872]	-5	hSpCas9	negative selection	5591051
57481977	57482000	5	+	27260156	BXPC3	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.1431277069657805	[508]	[449,468,440,579]	-3	hSpCas9	negative selection	5591052
57481937	57481960	5	+	27260156	BXPC3	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.04997977942652143	[842]	[862,719,992,829]	-1	hSpCas9	negative selection	5591053
57482572	57482595	5	-	27260156	A673	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.24149383116109857	[253]	[392,314,381,355]	6	hSpCas9	negative selection	5648019
57482162	57482185	5	+	27260156	A673	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.3696691685508572	[517]	[906,714,774,831]	8	hSpCas9	negative selection	5648020
57482170	57482193	5	-	27260156	A673	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.5923088466045472	[1518]	[2917,2660,2717,2716]	9	hSpCas9	negative selection	5648021
57482588	57482611	5	+	27260156	A673	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.24020235176527804	[1906]	[2122,1777,1921,1953]	-5	hSpCas9	negative selection	5712302
57481977	57482000	5	+	27260156	A673	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.08935590408259497	[508]	[673,481,602,549]	-2	hSpCas9	negative selection	5712303
57481937	57481960	5	+	27260156	A673	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.017509789076419424	[842]	[1091,973,911,1033]	0	hSpCas9	negative selection	5712304
57482572	57482595	5	-	27260156	A375	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.4576221454295935	[253]	[411,462,502,273]	6	hSpCas9	negative selection	5769270
57482162	57482185	5	+	27260156	A375	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.8523644820850738	[517]	[1109,1091,1013,1142]	9	hSpCas9	negative selection	5769271
57482170	57482193	5	-	27260156	A375	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.7399387829447461	[1518]	[2700,3480,3155,2614]	9	hSpCas9	negative selection	5769272
57482588	57482611	5	+	27260156	A375	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.3904821658797246	[1906]	[1746,1921,1522,1636]	-5	hSpCas9	negative selection	5833553
57481977	57482000	5	+	27260156	A375	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.08222652816009496	[508]	[698,752,380,451]	-1	hSpCas9	negative selection	5833554
57481937	57481960	5	+	27260156	A375	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.43564986643330894	[842]	[572,843,768,736]	-6	hSpCas9	negative selection	5833555
57482572	57482595	5	-	27260156	COLO741	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.38470485234755614	[253]	[380,410,470]	7	hSpCas9	negative selection	5890521
57482162	57482185	5	+	27260156	COLO741	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.49935016212622896	[517]	[1057,935,828]	8	hSpCas9	negative selection	5890522
57482170	57482193	5	-	27260156	COLO741	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.48614327459664897	[1518]	[3311,2480,2427]	8	hSpCas9	negative selection	5890523
57482588	57482611	5	+	27260156	COLO741	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.12147582129041057	[1906]	[2219,2603,1913]	-3	hSpCas9	negative selection	5954804
57481977	57482000	5	+	27260156	COLO741	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.5867309335326693	[508]	[642,536,1666]	9	hSpCas9	negative selection	5954805
57481937	57481960	5	+	27260156	COLO741	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.06833601534694012	[842]	[1155,1015,925]	-1	hSpCas9	negative selection	5954806
57482572	57482595	5	-	27260156	CAL120	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.4859112515299385	[253]	[630,387,338]	7	hSpCas9	negative selection	6011772
57482162	57482185	5	+	27260156	CAL120	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.5059871397894615	[517]	[902,874,964]	7	hSpCas9	negative selection	6011773
57482170	57482193	5	-	27260156	CAL120	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.6005877272990887	[1518]	[3004,2728,2883]	8	hSpCas9	negative selection	6011774
57482588	57482611	5	+	27260156	CAL120	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.04817279287109333	[1906]	[2521,2462,1939]	0	hSpCas9	negative selection	6076055
57481977	57482000	5	+	27260156	CAL120	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.2743321212244303	[508]	[729,350,520]	-4	hSpCas9	negative selection	6076056
57481937	57481960	5	+	27260156	CAL120	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.10281871943955667	[842]	[1131,871,949]	-1	hSpCas9	negative selection	6076057
57482572	57482595	5	-	27260156	CADOES1	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.08765087633769741	[253]	[200,349,188,264]	1	hSpCas9	negative selection	6133023
57482162	57482185	5	+	27260156	CADOES1	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.4361803155187345	[517]	[579,693,697,634]	7	hSpCas9	negative selection	6133024
57482170	57482193	5	-	27260156	CADOES1	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.7710356387194259	[1518]	[2897,2418,2177,2136]	9	hSpCas9	negative selection	6133025
57482588	57482611	5	+	27260156	CADOES1	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.4946297016363075	[1906]	[1267,1230,1230,1306]	-7	hSpCas9	negative selection	6197306
57481977	57482000	5	+	27260156	CADOES1	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.13476778976493797	[508]	[670,459,542,399]	2	hSpCas9	negative selection	6197307
57481937	57481960	5	+	27260156	CADOES1	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.06004445283800486	[842]	[728,1045,732,759]	1	hSpCas9	negative selection	6197308
57482572	57482595	5	-	27260156	EWS502	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.25344676967611324	[253]	[486,210,258,306]	4	hSpCas9	negative selection	6254274
57482162	57482185	5	+	27260156	EWS502	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.4615981211588912	[517]	[734,663,808,822]	7	hSpCas9	negative selection	6254275
57482170	57482193	5	-	27260156	EWS502	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.6083489715961312	[1518]	[2276,2651,2488,2392]	9	hSpCas9	negative selection	6254276
57482588	57482611	5	+	27260156	EWS502	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.5053532391574365	[1906]	[1453,1122,1338,1804]	-7	hSpCas9	negative selection	6318557
57481977	57482000	5	+	27260156	EWS502	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.01957981726242576	[508]	[546,519,349,781]	0	hSpCas9	negative selection	6318558
57481937	57481960	5	+	27260156	EWS502	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.07790867964198456	[842]	[734,812,850,1007]	-1	hSpCas9	negative selection	6318559
57482572	57482595	5	-	27260156	EW8	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.26162934665304205	[253]	[360,194,239,203]	5	hSpCas9	negative selection	6375525
57482162	57482185	5	+	27260156	EW8	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	-0.040191916411157755	[517]	[441,467,390,337]	0	hSpCas9	negative selection	6375526
57482170	57482193	5	-	27260156	EW8	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.617857746700077	[1518]	[2311,1990,1513,1844]	9	hSpCas9	negative selection	6375527
57482588	57482611	5	+	27260156	EW8	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.4725415809110618	[1906]	[1209,1377,1040,847]	-7	hSpCas9	negative selection	6439808
57481977	57482000	5	+	27260156	EW8	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.0029239912074741498	[508]	[486,336,533,274]	0	hSpCas9	negative selection	6439809
57481937	57481960	5	+	27260156	EW8	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.0005271450702335478	[842]	[602,612,653,856]	0	hSpCas9	negative selection	6439810
57482572	57482595	5	-	27260156	CORL105	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.271327391551882	[253]	[377,277,493,308]	5	hSpCas9	negative selection	6496776
57482162	57482185	5	+	27260156	CORL105	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.1650958089554072	[517]	[744,620,767,602]	3	hSpCas9	negative selection	6496777
57482170	57482193	5	-	27260156	CORL105	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.5584460706239518	[1518]	[2440,2657,2706,2674]	8	hSpCas9	negative selection	6496778
57482588	57482611	5	+	27260156	CORL105	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.2823908081460904	[1906]	[1631,1963,2166,1621]	-5	hSpCas9	negative selection	6561059
57481977	57482000	5	+	27260156	CORL105	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.14612039736197205	[508]	[540,454,718,468]	-3	hSpCas9	negative selection	6561060
57481937	57481960	5	+	27260156	CORL105	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.08043517834403113	[842]	[908,1059,1117,1092]	1	hSpCas9	negative selection	6561061
57482572	57482595	5	-	27260156	HS294T	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.3503144989483665	[253]	[68,158,144,132]	5	hSpCas9	negative selection	6618027
57482162	57482185	5	+	27260156	HS294T	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	-0.02410313021975595	[517]	[208,226,146,202]	0	hSpCas9	negative selection	6618028
57482170	57482193	5	-	27260156	HS294T	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.5381130147610469	[1518]	[914,816,626,1082]	7	hSpCas9	negative selection	6618029
57482588	57482611	5	+	27260156	HS294T	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.6712394275062128	[1906]	[317,516,438,613]	-7	hSpCas9	negative selection	6682310
57481977	57482000	5	+	27260156	HS294T	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.38240831062496894	[508]	[109,133,117,264]	-5	hSpCas9	negative selection	6682311
57481937	57481960	5	+	27260156	HS294T	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.07636843460949605	[842]	[269,403,333,375]	1	hSpCas9	negative selection	6682312
57482572	57482595	5	-	27260156	HCC44	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.3103196610682326	[253]	[482,250,353,359]	5	hSpCas9	negative selection	6739278
57482162	57482185	5	+	27260156	HCC44	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.3902748205679738	[517]	[703,730,835,803]	6	hSpCas9	negative selection	6739279
57482170	57482193	5	-	27260156	HCC44	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.6326601317197345	[1518]	[2568,2285,2966,2899]	9	hSpCas9	negative selection	6739280
57482588	57482611	5	+	27260156	HCC44	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.4883027904450361	[1906]	[1990,1182,1672,1409]	-6	hSpCas9	negative selection	6803561
57481977	57482000	5	+	27260156	HCC44	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.11942157340520523	[508]	[660,510,487,464]	-2	hSpCas9	negative selection	6803562
57481937	57481960	5	+	27260156	HCC44	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.31051930527632754	[842]	[789,645,1106,608]	-5	hSpCas9	negative selection	6803563
57482572	57482595	5	-	27260156	G402	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.6437448798961112	[253]	[636,398,555,365]	7	hSpCas9	negative selection	6860529
57482162	57482185	5	+	27260156	G402	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.8774567187787872	[517]	[1260,1430,894,1086]	9	hSpCas9	negative selection	6860530
57482170	57482193	5	-	27260156	G402	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.7607283943275076	[1518]	[2917,3772,3014,2861]	8	hSpCas9	negative selection	6860531
57482588	57482611	5	+	27260156	G402	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.33607179002876064	[1906]	[1892,1838,1410,2211]	-4	hSpCas9	negative selection	6924812
57481977	57482000	5	+	27260156	G402	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.4671073239900211	[508]	[387,464,431,499]	-5	hSpCas9	negative selection	6924813
57481937	57481960	5	+	27260156	G402	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.05759803367166083	[842]	[1272,886,1054,1080]	0	hSpCas9	negative selection	6924814
57482572	57482595	5	-	27260156	L33	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.10908859223884604	[253]	[266,146,131,259]	2	hSpCas9	negative selection	6981780
57482162	57482185	5	+	27260156	L33	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	-0.018488058451754857	[517]	[472,204,371,481]	0	hSpCas9	negative selection	6981781
57482170	57482193	5	-	27260156	L33	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.41504748373556466	[1518]	[1969,732,1454,2029]	8	hSpCas9	negative selection	6981782
57482588	57482611	5	+	27260156	L33	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.2458754034178181	[1906]	[1514,648,1058,1650]	-5	hSpCas9	negative selection	7046063
57481977	57482000	5	+	27260156	L33	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.17929165642746475	[508]	[418,164,298,500]	-4	hSpCas9	negative selection	7046064
57481937	57481960	5	+	27260156	L33	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.05847951589226308	[842]	[795,437,518,822]	1	hSpCas9	negative selection	7046065
57482572	57482595	5	-	27260156	K562	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	-0.0018611518657984938	[253]	[150,200,171,352]	0	hSpCas9	negative selection	7103031
57482162	57482185	5	+	27260156	K562	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.5424397510569389	[517]	[597,621,731,709]	7	hSpCas9	negative selection	7103032
57482170	57482193	5	-	27260156	K562	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.7661265397115578	[1518]	[3156,2368,2282,1517]	8	hSpCas9	negative selection	7103033
57482588	57482611	5	+	27260156	K562	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.6714325270707291	[1906]	[1355,869,709,1295]	-7	hSpCas9	negative selection	7167314
57481977	57482000	5	+	27260156	K562	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.07136742583085394	[508]	[319,772,525,300]	0	hSpCas9	negative selection	7167315
57481937	57481960	5	+	27260156	K562	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.15446307003880166	[842]	[843,623,601,631]	-2	hSpCas9	negative selection	7167316
57482572	57482595	5	-	27260156	HT29	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.40314491420942605	[253]	[393,472,397,373]	7	hSpCas9	negative selection	7224282
57482162	57482185	5	+	27260156	HT29	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.277628023204203	[517]	[840,607,923,677]	5	hSpCas9	negative selection	7224283
57482170	57482193	5	-	27260156	HT29	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.634435830012609	[1518]	[2850,3479,2548,2643]	9	hSpCas9	negative selection	7224284
57482588	57482611	5	+	27260156	HT29	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.34518257159458976	[1906]	[1972,1890,1665,1778]	-6	hSpCas9	negative selection	7288565
57481977	57482000	5	+	27260156	HT29	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.08074885559929326	[508]	[536,626,811,384]	-2	hSpCas9	negative selection	7288566
57481937	57481960	5	+	27260156	HT29	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.008889527703965228	[842]	[1173,1100,945,925]	0	hSpCas9	negative selection	7288567
57482572	57482595	5	-	27260156	MHHES1	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.13250309122623638	[253]	[277,411,393,196]	2	hSpCas9	negative selection	7345533
57482162	57482185	5	+	27260156	MHHES1	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.3540268764074218	[517]	[754,709,899,626]	6	hSpCas9	negative selection	7345534
57482170	57482193	5	-	27260156	MHHES1	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.6446026038964707	[1518]	[2597,2788,3009,2325]	9	hSpCas9	negative selection	7345535
57482588	57482611	5	+	27260156	MHHES1	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.27881323268232916	[1906]	[1976,2085,1934,1228]	-5	hSpCas9	negative selection	7409816
57481977	57482000	5	+	27260156	MHHES1	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.10870881172964843	[508]	[528,411,647,516]	-2	hSpCas9	negative selection	7409817
57481937	57481960	5	+	27260156	MHHES1	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.1496838342086797	[842]	[1097,928,857,612]	-3	hSpCas9	negative selection	7409818
57482572	57482595	5	-	27260156	MEWO	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.15240397081581136	[253]	[394,187,234]	3	hSpCas9	negative selection	7466784
57482162	57482185	5	+	27260156	MEWO	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.2819642336878388	[517]	[540,630,585]	6	hSpCas9	negative selection	7466785
57482170	57482193	5	-	27260156	MEWO	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.4920077966996146	[1518]	[2199,1905,1928]	8	hSpCas9	negative selection	7466786
57482588	57482611	5	+	27260156	MEWO	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.30515308772966643	[1906]	[1605,1448,1307]	-6	hSpCas9	negative selection	7531067
57481977	57482000	5	+	27260156	MEWO	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.15375239007287914	[508]	[469,471,349]	-3	hSpCas9	negative selection	7531068
57481937	57481960	5	+	27260156	MEWO	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.10540638656220014	[842]	[987,640,619]	-2	hSpCas9	negative selection	7531069
57482572	57482595	5	-	27260156	LNCAPCLONEFGC	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.29024377772486787	[253]	[231,325,346,227]	4	hSpCas9	negative selection	7588035
57482162	57482185	5	+	27260156	LNCAPCLONEFGC	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.7092593876772016	[517]	[842,532,940,790]	9	hSpCas9	negative selection	7588036
57482170	57482193	5	-	27260156	LNCAPCLONEFGC	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.7658771200942562	[1518]	[2305,1874,2967,2332]	9	hSpCas9	negative selection	7588037
57482588	57482611	5	+	27260156	LNCAPCLONEFGC	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.37020185344983747	[1906]	[1407,1088,1598,1302]	-5	hSpCas9	negative selection	7652318
57481977	57482000	5	+	27260156	LNCAPCLONEFGC	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.05507252292846966	[508]	[528,472,497,417]	0	hSpCas9	negative selection	7652319
57481937	57481960	5	+	27260156	LNCAPCLONEFGC	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.2442645382321318	[842]	[699,567,729,596]	-4	hSpCas9	negative selection	7652320
57482572	57482595	5	-	27260156	PANC0327	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	-0.12813388514728175	[253]	[201,208,179,233]	-2	hSpCas9	negative selection	7709286
57482162	57482185	5	+	27260156	PANC0327	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	-0.0694968747885049	[517]	[453,408,460,434]	-1	hSpCas9	negative selection	7709287
57482170	57482193	5	-	27260156	PANC0327	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.602166139438354	[1518]	[2631,1577,2420,1670]	8	hSpCas9	negative selection	7709288
57482588	57482611	5	+	27260156	PANC0327	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	0.13628196545815507	[1906]	[1322,1588,2179,2345]	2	hSpCas9	negative selection	7773569
57481977	57482000	5	+	27260156	PANC0327	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.15930692052460427	[508]	[570,264,568,650]	2	hSpCas9	negative selection	7773570
57481937	57481960	5	+	27260156	PANC0327	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.17324719370145925	[842]	[855,818,1043,662]	2	hSpCas9	negative selection	7773571
57482572	57482595	5	-	27260156	NCIH2009	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.20283269666239534	[253]	[534,334,380]	2	hSpCas9	negative selection	7830537
57482162	57482185	5	+	27260156	NCIH2009	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.31297359879396447	[517]	[1190,918,642]	4	hSpCas9	negative selection	7830538
57482170	57482193	5	-	27260156	NCIH2009	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.6113303010053011	[1518]	[3827,3005,3006]	8	hSpCas9	negative selection	7830539
57482588	57482611	5	+	27260156	NCIH2009	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.5241280430966626	[1906]	[2313,1647,1687]	-6	hSpCas9	negative selection	7894820
57481977	57482000	5	+	27260156	NCIH2009	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.17801149217917084	[508]	[943,577,425]	-2	hSpCas9	negative selection	7894821
57481937	57481960	5	+	27260156	NCIH2009	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.48685518184077925	[842]	[1135,804,637]	-6	hSpCas9	negative selection	7894822
57482572	57482595	5	-	27260156	NCIH1373	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.6434914683703297	[253]	[294,697,349,99]	6	hSpCas9	negative selection	7951788
57482162	57482185	5	+	27260156	NCIH1373	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.3968072240742534	[517]	[1136,746,638,152]	4	hSpCas9	negative selection	7951789
57482170	57482193	5	-	27260156	NCIH1373	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	1.1991726724160194	[1518]	[5380,3221,2999,1146]	9	hSpCas9	negative selection	7951790
57482588	57482611	5	+	27260156	NCIH1373	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.525368724910471	[1906]	[1491,648,2250,426]	-5	hSpCas9	negative selection	8016071
57481977	57482000	5	+	27260156	NCIH1373	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.4973429969159125	[508]	[312,336,767,43]	-5	hSpCas9	negative selection	8016072
57481937	57481960	5	+	27260156	NCIH1373	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-1.1034267351899798	[842]	[741,403,350,79]	-8	hSpCas9	negative selection	8016073
57482572	57482595	5	-	27260156	PATU8902	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.30081319982240207	[253]	[480,337,558,313]	3	hSpCas9	negative selection	8073039
57482162	57482185	5	+	27260156	PATU8902	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.6476479033890084	[517]	[1789,680,1023,1020]	6	hSpCas9	negative selection	8073040
57482170	57482193	5	-	27260156	PATU8902	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	1.217135589466397	[1518]	[5691,4418,4579,5031]	9	hSpCas9	negative selection	8073041
57482588	57482611	5	+	27260156	PATU8902	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.7213784348438903	[1906]	[1678,1867,982,2124]	-6	hSpCas9	negative selection	8137322
57481977	57482000	5	+	27260156	PATU8902	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.19528757854317405	[508]	[617,371,766,682]	-2	hSpCas9	negative selection	8137323
57481937	57481960	5	+	27260156	PATU8902	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.1686249074420576	[842]	[1499,748,1283,1796]	1	hSpCas9	negative selection	8137324
57482572	57482595	5	-	27260156	PANC1	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.38981354442540395	[253]	[326,286,260,265]	6	hSpCas9	negative selection	8194290
57482162	57482185	5	+	27260156	PANC1	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.5776609590662356	[517]	[591,793,782,527]	8	hSpCas9	negative selection	8194291
57482170	57482193	5	-	27260156	PANC1	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.5146843443413986	[1518]	[1483,2406,1664,1968]	8	hSpCas9	negative selection	8194292
57482588	57482611	5	+	27260156	PANC1	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.3992012666560645	[1906]	[1205,1322,1436,1034]	-6	hSpCas9	negative selection	8258573
57481977	57482000	5	+	27260156	PANC1	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.10269744271038342	[508]	[433,614,323,306]	-2	hSpCas9	negative selection	8258574
57481937	57481960	5	+	27260156	PANC1	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.13041828068749772	[842]	[618,913,721,465]	-2	hSpCas9	negative selection	8258575
57482572	57482595	5	-	27260156	PANC0813	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.49780736108541535	[253]	[672,343,455,244]	7	hSpCas9	negative selection	8315541
57482162	57482185	5	+	27260156	PANC0813	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.05730639288251024	[517]	[523,627,687,678]	0	hSpCas9	negative selection	8315542
57482170	57482193	5	-	27260156	PANC0813	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.4955951456091092	[1518]	[2684,2733,2666,2016]	7	hSpCas9	negative selection	8315543
57482588	57482611	5	+	27260156	PANC0813	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.24045055857095798	[1906]	[2005,2200,1701,1692]	-4	hSpCas9	negative selection	8379824
57481977	57482000	5	+	27260156	PANC0813	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.21183611769191912	[508]	[653,543,531,355]	-3	hSpCas9	negative selection	8379825
57481937	57481960	5	+	27260156	PANC0813	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.31103989545160926	[842]	[775,966,775,676]	-5	hSpCas9	negative selection	8379826
57482572	57482595	5	-	27260156	RDES	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.48380463199016965	[253]	[326,322,486,532]	7	hSpCas9	negative selection	8436792
57482162	57482185	5	+	27260156	RDES	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.40133392241560584	[517]	[585,702,917,1007]	6	hSpCas9	negative selection	8436793
57482170	57482193	5	-	27260156	RDES	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.7202707756794522	[1518]	[2331,2776,3208,3312]	9	hSpCas9	negative selection	8436794
57482588	57482611	5	+	27260156	RDES	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.5871214882417839	[1906]	[1117,1159,1601,2128]	-7	hSpCas9	negative selection	8501075
57481977	57482000	5	+	27260156	RDES	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.07842075561623747	[508]	[427,540,881,670]	1	hSpCas9	negative selection	8501076
57481937	57481960	5	+	27260156	RDES	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.38752990967567746	[842]	[505,756,775,993]	-6	hSpCas9	negative selection	8501077
57482572	57482595	5	-	27260156	PC3	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.3957814365870604	[253]	[216,333,450,395]	8	hSpCas9	negative selection	8558043
57482162	57482185	5	+	27260156	PC3	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.3934255500962218	[517]	[466,512,1192,775]	8	hSpCas9	negative selection	8558044
57482170	57482193	5	-	27260156	PC3	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.3146711366972792	[1518]	[1209,1547,3450,2071]	6	hSpCas9	negative selection	8558045
57482588	57482611	5	+	27260156	PC3	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.1432473292530012	[1906]	[1263,1340,3012,1804]	-3	hSpCas9	negative selection	8622326
57481977	57482000	5	+	27260156	PC3	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.3119622160368549	[508]	[184,512,642,447]	-6	hSpCas9	negative selection	8622327
57481937	57481960	5	+	27260156	PC3	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.1510817725849618	[842]	[618,613,1399,613]	-3	hSpCas9	negative selection	8622328
57482572	57482595	5	-	27260156	PATU8988T	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	-0.07808318043373097	[253]	[217,459,110,157]	-1	hSpCas9	negative selection	8679294
57482162	57482185	5	+	27260156	PATU8988T	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.2892035595877383	[517]	[598,692,618,536]	5	hSpCas9	negative selection	8679295
57482170	57482193	5	-	27260156	PATU8988T	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.47940022457889175	[1518]	[1829,2562,2079,1734]	7	hSpCas9	negative selection	8679296
57482588	57482611	5	+	27260156	PATU8988T	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.22276074288760528	[1906]	[1943,1570,1452,1328]	-4	hSpCas9	negative selection	8743577
57481977	57482000	5	+	27260156	PATU8988T	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.1274669519221754	[508]	[829,469,473,354]	2	hSpCas9	negative selection	8743578
57481937	57481960	5	+	27260156	PATU8988T	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.2693384338033773	[842]	[842,1173,911,1019]	4	hSpCas9	negative selection	8743579
57482572	57482595	5	-	27260156	T47D	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.47116707068873226	[253]	[328,345,528,440]	8	hSpCas9	negative selection	8800545
57482162	57482185	5	+	27260156	T47D	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.28533779891480715	[517]	[713,763,726,733]	6	hSpCas9	negative selection	8800546
57482170	57482193	5	-	27260156	T47D	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.49914255567675103	[1518]	[2508,2333,2438,2744]	9	hSpCas9	negative selection	8800547
57482588	57482611	5	+	27260156	T47D	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.5510384554761083	[1906]	[1497,1552,1470,1540]	-8	hSpCas9	negative selection	8864828
57481977	57482000	5	+	27260156	T47D	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.18723634723423016	[508]	[521,503,582,472]	-4	hSpCas9	negative selection	8864829
57481937	57481960	5	+	27260156	T47D	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.041245784727936385	[842]	[962,932,845,1082]	-1	hSpCas9	negative selection	8864830
57482572	57482595	5	-	27260156	SU8686	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.2602672689818437	[253]	[304,341,291,250]	4	hSpCas9	negative selection	8921796
57482162	57482185	5	+	27260156	SU8686	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.25558238056874927	[517]	[595,448,755,685]	4	hSpCas9	negative selection	8921797
57482170	57482193	5	-	27260156	SU8686	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.4373817548404133	[1518]	[1686,1831,2070,2732]	7	hSpCas9	negative selection	8921798
57482588	57482611	5	+	27260156	SU8686	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.26740684316997343	[1906]	[1360,1417,1737,1847]	-4	hSpCas9	negative selection	8986079
57481977	57482000	5	+	27260156	SU8686	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.080463253691042	[508]	[525,396,712,514]	1	hSpCas9	negative selection	8986080
57481937	57481960	5	+	27260156	SU8686	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.19880556342652578	[842]	[576,665,864,847]	-3	hSpCas9	negative selection	8986081
57482572	57482595	5	-	27260156	SKES1	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.10157315970574243	[253]	[336,343,193,232]	2	hSpCas9	negative selection	9043047
57482162	57482185	5	+	27260156	SKES1	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.43471076902618555	[517]	[699,852,638,622]	8	hSpCas9	negative selection	9043048
57482170	57482193	5	-	27260156	SKES1	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.516116868200063	[1518]	[2733,2273,1929,1840]	9	hSpCas9	negative selection	9043049
57482588	57482611	5	+	27260156	SKES1	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.4946242961534639	[1906]	[1468,1452,1282,1225]	-8	hSpCas9	negative selection	9107330
57481977	57482000	5	+	27260156	SKES1	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.26385618758549784	[508]	[342,567,409,377]	-5	hSpCas9	negative selection	9107331
57481937	57481960	5	+	27260156	SKES1	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.10680997582915064	[842]	[951,859,791,569]	-2	hSpCas9	negative selection	9107332
57482572	57482595	5	-	27260156	TOV112D	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	-0.17296886577331172	[253]	[184,370,131,245]	-3	hSpCas9	negative selection	9164298
57482162	57482185	5	+	27260156	TOV112D	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.2604933847450014	[517]	[570,703,752,476]	5	hSpCas9	negative selection	9164299
57482170	57482193	5	-	27260156	TOV112D	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.6849007862473442	[1518]	[2659,3018,2177,2090]	9	hSpCas9	negative selection	9164300
57482588	57482611	5	+	27260156	TOV112D	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.5128683214442049	[1906]	[1480,1432,1307,1169]	-7	hSpCas9	negative selection	9228581
57481977	57482000	5	+	27260156	TOV112D	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.10879537649746544	[508]	[552,568,567,513]	2	hSpCas9	negative selection	9228582
57481937	57481960	5	+	27260156	TOV112D	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.23919803737188705	[842]	[1044,753,551,550]	-5	hSpCas9	negative selection	9228583
57482572	57482595	5	-	27260156	TC71	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.2361256369175534	[253]	[347,378,205,354]	6	hSpCas9	negative selection	9285549
57482162	57482185	5	+	27260156	TC71	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.25548195547998415	[517]	[714,635,616,684]	6	hSpCas9	negative selection	9285550
57482170	57482193	5	-	27260156	TC71	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.39974146697461976	[1518]	[2018,2218,2090,2275]	8	hSpCas9	negative selection	9285551
57482588	57482611	5	+	27260156	TC71	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.16512183760759513	[1906]	[1722,1709,1789,2088]	-4	hSpCas9	negative selection	9349832
57481977	57482000	5	+	27260156	TC71	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	0.1759312433636867	[508]	[761,536,592,567]	4	hSpCas9	negative selection	9349833
57481937	57481960	5	+	27260156	TC71	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.04012355962797709	[842]	[995,972,904,835]	1	hSpCas9	negative selection	9349834
57482572	57482595	5	-	27260156	TC32	viability	TCCTCGACACCAGGGCGTTATGG	ACTBL2	ENSG00000169067	0.1732345382978695	[253]	[201,204,358,347]	3	hSpCas9	negative selection	9406800
57482162	57482185	5	+	27260156	TC32	viability	TGCCAGATCCAGGCGTAGAATGG	ACTBL2	ENSG00000169067	0.2174489946921767	[517]	[434,401,733,780]	4	hSpCas9	negative selection	9406801
57482170	57482193	5	-	27260156	TC32	viability	GCCTCATGCCATTCTACGCCTGG	ACTBL2	ENSG00000169067	0.6712769973001789	[1518]	[2349,1561,2873,2550]	9	hSpCas9	negative selection	9406802
57482588	57482611	5	+	27260156	TC32	viability	TCGAGGACGCCCTATCATGGAGG	ACTBL2	ENSG00000169067	-0.47111870745891093	[1906]	[1154,922,1624,1626]	-7	hSpCas9	negative selection	9471083
57481977	57482000	5	+	27260156	TC32	viability	GGAAGTTCATAGCTCCGTTCCGG	ACTBL2	ENSG00000169067	-0.19677708525339846	[508]	[461,299,508,427]	-4	hSpCas9	negative selection	9471084
57481937	57481960	5	+	27260156	TC32	viability	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.0929399785894155	[842]	[555,654,957,857]	-2	hSpCas9	negative selection	9471085
57481782	57481805	5	-	27869803	HPAFII	viability after 27 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.8495276908883007	[144]	[210,75,NaN]	7	hSpCas9	negative selection	9592209
57481793	57481816	5	+	27869803	HPAFII	viability after 27 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.3874328269286516	[169]	[57,165,NaN]	3	hSpCas9	negative selection	9592210
57481937	57481960	5	+	27869803	HPAFII	viability after 27 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.18358126835497124	[161]	[81,108,NaN]	1	hSpCas9	negative selection	9592211
57481966	57481989	5	-	27869803	HPAFII	viability after 27 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.9098161748998638	[259]	[354,174,NaN]	7	hSpCas9	negative selection	9592212
57482159	57482182	5	-	27869803	HPAFII	viability after 27 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.47947445993581517	[283]	[159,62,NaN]	-4	hSpCas9	negative selection	9592213
57482580	57482603	5	-	27869803	HPAFII	viability after 27 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.505623541157069	[227]	[191,151,NaN]	4	hSpCas9	negative selection	9592214
57481782	57481805	5	-	27869803	HPAFII	viability after 15 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.16404681299335322	[144]	[374,49,NaN]	2	hSpCas9	negative selection	9674658
57481793	57481816	5	+	27869803	HPAFII	viability after 15 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	-0.26049922974976725	[169]	[199,122,NaN]	-3	hSpCas9	negative selection	9674659
57481937	57481960	5	+	27869803	HPAFII	viability after 15 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.09416921983580195	[161]	[183,186,NaN]	1	hSpCas9	negative selection	9674660
57481966	57481989	5	-	27869803	HPAFII	viability after 15 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.39978728391794377	[259]	[425,332,NaN]	4	hSpCas9	negative selection	9674661
57482159	57482182	5	-	27869803	HPAFII	viability after 15 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.478736494987849	[283]	[358,131,NaN]	-5	hSpCas9	negative selection	9674662
57482580	57482603	5	-	27869803	HPAFII	viability after 15 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.24537210962479228	[227]	[480,171,NaN]	3	hSpCas9	negative selection	9674663
57481782	57481805	5	-	27869803	ASPC1	viability after 36 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.2941998106733448	[345]	[84,76,123]	-3	hSpCas9	negative selection	9757107
57481793	57481816	5	+	27869803	ASPC1	viability after 36 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	-0.0108494919275961	[366]	[197,154,53]	0	hSpCas9	negative selection	9757108
57481937	57481960	5	+	27869803	ASPC1	viability after 36 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.23258778338915942	[485]	[146,151,134]	-2	hSpCas9	negative selection	9757109
57481966	57481989	5	-	27869803	ASPC1	viability after 36 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.74754528424887	[568]	[380,201,400]	7	hSpCas9	negative selection	9757110
57482159	57482182	5	-	27869803	ASPC1	viability after 36 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.15938130815862472	[832]	[437,345,224]	1	hSpCas9	negative selection	9757111
57482580	57482603	5	-	27869803	ASPC1	viability after 36 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.03453451864429957	[424]	[117,97,216]	0	hSpCas9	negative selection	9757112
57481782	57481805	5	-	27869803	PATU8988S	viability after 35 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.20480892552780483	[318]	[99,122,NaN]	-2	hSpCas9	negative selection	9839556
57481793	57481816	5	+	27869803	PATU8988S	viability after 35 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.49278056219464283	[375]	[252,172,NaN]	5	hSpCas9	negative selection	9839557
57481937	57481960	5	+	27869803	PATU8988S	viability after 35 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.24804887216988436	[507]	[233,251,NaN]	3	hSpCas9	negative selection	9839558
57481966	57481989	5	-	27869803	PATU8988S	viability after 35 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.18034085050791113	[617]	[299,263,NaN]	2	hSpCas9	negative selection	9839559
57482159	57482182	5	-	27869803	PATU8988S	viability after 35 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.4959521915595976	[635]	[463,257,NaN]	5	hSpCas9	negative selection	9839560
57482580	57482603	5	-	27869803	PATU8988S	viability after 35 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.050307028859129854	[429]	[103,254,NaN]	0	hSpCas9	negative selection	9839561
57481782	57481805	5	-	27869803	PATU8988S	viability after 31 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.07690272784324759	[318]	[102,142,NaN]	-1	hSpCas9	negative selection	9922005
57481793	57481816	5	+	27869803	PATU8988S	viability after 31 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.43866391045661424	[375]	[222,177,NaN]	5	hSpCas9	negative selection	9922006
57481937	57481960	5	+	27869803	PATU8988S	viability after 31 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.29009123933925984	[507]	[226,273,NaN]	3	hSpCas9	negative selection	9922007
57481966	57481989	5	-	27869803	PATU8988S	viability after 31 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	0.28937357169449307	[617]	[283,322,NaN]	3	hSpCas9	negative selection	9922008
57482159	57482182	5	-	27869803	PATU8988S	viability after 31 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	0.5859257005878221	[635]	[454,285,NaN]	7	hSpCas9	negative selection	9922009
57482580	57482603	5	-	27869803	PATU8988S	viability after 31 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	-0.30332600065282267	[429]	[79,213,NaN]	-3	hSpCas9	negative selection	9922010
57481782	57481805	5	-	27869803	HPAFII	viability after 35 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	1.3009537921820977	[144]	[265,84,NaN]	8	hSpCas9	negative selection	10004454
57481793	57481816	5	+	27869803	HPAFII	viability after 35 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.5428091927560039	[169]	[51,207,NaN]	3	hSpCas9	negative selection	10004455
57481937	57481960	5	+	27869803	HPAFII	viability after 35 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	-0.12249452578495523	[161]	[40,113,NaN]	0	hSpCas9	negative selection	10004456
57481966	57481989	5	-	27869803	HPAFII	viability after 35 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	1.4805994771253586	[259]	[530,182,NaN]	8	hSpCas9	negative selection	10004457
57482159	57482182	5	-	27869803	HPAFII	viability after 35 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.11589615754933616	[283]	[190,66,NaN]	0	hSpCas9	negative selection	10004458
57482580	57482603	5	-	27869803	HPAFII	viability after 35 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.17108376445301532	[227]	[160,94,NaN]	1	hSpCas9	negative selection	10004459
57481782	57481805	5	-	27869803	HPAFII	viability after 31 days	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	1.0650336248289929	[144]	[242,90,NaN]	7	hSpCas9	negative selection	10086903
57481793	57481816	5	+	27869803	HPAFII	viability after 31 days	GGTGCTCCCTCCAGATAACACGG	ACTBL2	ENSG00000169067	0.5292901745000475	[169]	[74,205,NaN]	4	hSpCas9	negative selection	10086904
57481937	57481960	5	+	27869803	HPAFII	viability after 31 days	TCGGAAGCGTTCATTCCCAATGG	ACTBL2	ENSG00000169067	0.09354027181466218	[161]	[85,108,NaN]	0	hSpCas9	negative selection	10086905
57481966	57481989	5	-	27869803	HPAFII	viability after 31 days	CTATGAACTTCCTGATGGGCAGG	ACTBL2	ENSG00000169067	1.0471201118642182	[259]	[368,227,NaN]	7	hSpCas9	negative selection	10086906
57482159	57482182	5	-	27869803	HPAFII	viability after 31 days	TTCTACGCCTGGATCTGGCAGGG	ACTBL2	ENSG00000169067	-0.9708122657504058	[283]	[121,36,NaN]	-6	hSpCas9	negative selection	10086907
57482580	57482603	5	-	27869803	HPAFII	viability after 31 days	ATAGGGCGTCCTCGACACCAGGG	ACTBL2	ENSG00000169067	0.21674202267557247	[227]	[141,155,NaN]	1	hSpCas9	negative selection	10086908
57482590	57482613	5	+	28162770	P31FUJ	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.1827035928240132	[282]	[292]	-2	hSpCas9	negative selection	10106338
57481782	57481805	5	-	28162770	P31FUJ	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.4026253632897654	[514]	[799]	4	hSpCas9	negative selection	10106339
57482533	57482556	5	-	28162770	P31FUJ	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.03686965334155978	[505]	[609]	0	hSpCas9	negative selection	10106340
57482479	57482502	5	-	28162770	P31FUJ	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.7780861117283575	[65]	[132]	8	hSpCas9	negative selection	10106341
57482383	57482406	5	-	28162770	P31FUJ	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	-0.051864210249648046	[927]	[1051]	0	hSpCas9	negative selection	10106342
57482374	57482397	5	+	28162770	P31FUJ	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	1.300416721212779	[122]	[355]	9	hSpCas9	negative selection	10106343
57482245	57482268	5	-	28162770	P31FUJ	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.832592213556627	[495]	[1037]	8	hSpCas9	negative selection	10106344
57482174	57482197	5	+	28162770	P31FUJ	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.47674793217142697	[424]	[694]	5	hSpCas9	negative selection	10106345
57482078	57482101	5	+	28162770	P31FUJ	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.24463183200233285	[904]	[1259]	2	hSpCas9	negative selection	10106346
57482041	57482064	5	-	28162770	P31FUJ	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.9152506165504277	[383]	[850]	9	hSpCas9	negative selection	10106347
57482590	57482613	5	+	28162770	TF1	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[299]	1	hSpCas9	negative selection	10275704
57481782	57481805	5	-	28162770	TF1	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[284]	1	hSpCas9	negative selection	10275705
57482533	57482556	5	-	28162770	TF1	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[397]	1	hSpCas9	negative selection	10275706
57482479	57482502	5	-	28162770	TF1	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10275707
57482383	57482406	5	-	28162770	TF1	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[697]	1	hSpCas9	negative selection	10275708
57482374	57482397	5	+	28162770	TF1	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10275709
57482245	57482268	5	-	28162770	TF1	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[349]	1	hSpCas9	negative selection	10275710
57482174	57482197	5	+	28162770	TF1	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[310]	1	hSpCas9	negative selection	10275711
57482078	57482101	5	+	28162770	TF1	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[604]	1	hSpCas9	negative selection	10275712
57482041	57482064	5	-	28162770	TF1	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	NaN	[NaN]	[353]	1	hSpCas9	negative selection	10275713
57482590	57482613	5	+	28162770	SKM1	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.027862395468565393	[93]	[162]	0	hSpCas9	negative selection	10445070
57481782	57481805	5	-	28162770	SKM1	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.04604197223993589	[145]	[249]	0	hSpCas9	negative selection	10445071
57482533	57482556	5	-	28162770	SKM1	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.43523486327367555	[186]	[446]	4	hSpCas9	negative selection	10445072
57482479	57482502	5	-	28162770	SKM1	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.40696419874316137	[23]	[31]	-3	hSpCas9	negative selection	10445073
57482383	57482406	5	-	28162770	SKM1	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.10059379829238813	[267]	[507]	1	hSpCas9	negative selection	10445074
57482374	57482397	5	+	28162770	SKM1	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	-0.5000736031346433	[71]	[89]	-4	hSpCas9	negative selection	10445075
57482245	57482268	5	-	28162770	SKM1	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	-0.6589434160679599	[116]	[130]	-5	hSpCas9	negative selection	10445076
57482174	57482197	5	+	28162770	SKM1	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	1.0569064850606327	[58]	[216]	8	hSpCas9	negative selection	10445077
57482078	57482101	5	+	28162770	SKM1	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.2039267669685203	[192]	[392]	2	hSpCas9	negative selection	10445078
57482041	57482064	5	-	28162770	SKM1	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.9366088901841803	[85]	[290]	8	hSpCas9	negative selection	10445079
57482590	57482613	5	+	28162770	SKM1	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.027862395468565393	[93]	[162]	0	hSpCas9	negative selection	10614436
57481782	57481805	5	-	28162770	SKM1	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.04604197223993589	[145]	[249]	0	hSpCas9	negative selection	10614437
57482533	57482556	5	-	28162770	SKM1	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.43523486327367555	[186]	[446]	4	hSpCas9	negative selection	10614438
57482479	57482502	5	-	28162770	SKM1	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.40696419874316137	[23]	[31]	-3	hSpCas9	negative selection	10614439
57482383	57482406	5	-	28162770	SKM1	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.10059379829238813	[267]	[507]	1	hSpCas9	negative selection	10614440
57482374	57482397	5	+	28162770	SKM1	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	-0.5000736031346433	[71]	[89]	-4	hSpCas9	negative selection	10614441
57482245	57482268	5	-	28162770	SKM1	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	-0.6589434160679599	[116]	[130]	-5	hSpCas9	negative selection	10614442
57482174	57482197	5	+	28162770	SKM1	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	1.0569064850606327	[58]	[216]	8	hSpCas9	negative selection	10614443
57482078	57482101	5	+	28162770	SKM1	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.2039267669685203	[192]	[392]	2	hSpCas9	negative selection	10614444
57482041	57482064	5	-	28162770	SKM1	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.9366088901841803	[85]	[290]	8	hSpCas9	negative selection	10614445
57482590	57482613	5	+	28162770	PL21	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.06124693846299134	[349]	[145]	0	hSpCas9	negative selection	10783802
57481782	57481805	5	-	28162770	PL21	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.2796681401797615	[409]	[146]	-2	hSpCas9	negative selection	10783803
57482533	57482556	5	-	28162770	PL21	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	-0.21095501532006855	[608]	[228]	-1	hSpCas9	negative selection	10783804
57482479	57482502	5	-	28162770	PL21	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-1.5934095080432533	[103]	[14]	-7	hSpCas9	negative selection	10783805
57482383	57482406	5	-	28162770	PL21	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.7725497432542014	[884]	[657]	6	hSpCas9	negative selection	10783806
57482374	57482397	5	+	28162770	PL21	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	0.804210938158181	[149]	[113]	7	hSpCas9	negative selection	10783807
57482245	57482268	5	-	28162770	PL21	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	-0.29350771948589005	[351]	[124]	-2	hSpCas9	negative selection	10783808
57482174	57482197	5	+	28162770	PL21	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.26852658946957036	[205]	[107]	2	hSpCas9	negative selection	10783809
57482078	57482101	5	+	28162770	PL21	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	-0.6326135800024193	[658]	[184]	-4	hSpCas9	negative selection	10783810
57482041	57482064	5	-	28162770	PL21	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.4307525426307366	[299]	[175]	4	hSpCas9	negative selection	10783811
57482590	57482613	5	+	28162770	P31FUJ	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.1827035928240132	[282]	[292]	-2	hSpCas9	negative selection	10953168
57481782	57481805	5	-	28162770	P31FUJ	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.4026253632897654	[514]	[799]	4	hSpCas9	negative selection	10953169
57482533	57482556	5	-	28162770	P31FUJ	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.03686965334155978	[505]	[609]	0	hSpCas9	negative selection	10953170
57482479	57482502	5	-	28162770	P31FUJ	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.7780861117283575	[65]	[132]	8	hSpCas9	negative selection	10953171
57482383	57482406	5	-	28162770	P31FUJ	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	-0.051864210249648046	[927]	[1051]	0	hSpCas9	negative selection	10953172
57482374	57482397	5	+	28162770	P31FUJ	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	1.300416721212779	[122]	[355]	9	hSpCas9	negative selection	10953173
57482245	57482268	5	-	28162770	P31FUJ	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.832592213556627	[495]	[1037]	8	hSpCas9	negative selection	10953174
57482174	57482197	5	+	28162770	P31FUJ	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.47674793217142697	[424]	[694]	5	hSpCas9	negative selection	10953175
57482078	57482101	5	+	28162770	P31FUJ	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.24463183200233285	[904]	[1259]	2	hSpCas9	negative selection	10953176
57482041	57482064	5	-	28162770	P31FUJ	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.9152506165504277	[383]	[850]	9	hSpCas9	negative selection	10953177
57482590	57482613	5	+	28162770	OCIAML5	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	1.1291968665544172	[154]	[611]	8	hSpCas9	negative selection	11122534
57481782	57481805	5	-	28162770	OCIAML5	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.6556693580604938	[287]	[329]	-4	hSpCas9	negative selection	11122535
57482533	57482556	5	-	28162770	OCIAML5	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.1732243484337419	[310]	[632]	1	hSpCas9	negative selection	11122536
57482479	57482502	5	-	28162770	OCIAML5	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.48962477884479516	[57]	[146]	4	hSpCas9	negative selection	11122537
57482383	57482406	5	-	28162770	OCIAML5	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.0861174215342475	[452]	[867]	0	hSpCas9	negative selection	11122538
57482374	57482397	5	+	28162770	OCIAML5	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	1.0092271583044108	[59]	[217]	8	hSpCas9	negative selection	11122539
57482245	57482268	5	-	28162770	OCIAML5	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.048816595779898275	[368]	[688]	0	hSpCas9	negative selection	11122540
57482174	57482197	5	+	28162770	OCIAML5	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	-0.24265102641830183	[233]	[356]	-2	hSpCas9	negative selection	11122541
57482078	57482101	5	+	28162770	OCIAML5	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.5519036245120101	[457]	[1211]	5	hSpCas9	negative selection	11122542
57482041	57482064	5	-	28162770	OCIAML5	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	1.0686701506113496	[158]	[601]	8	hSpCas9	negative selection	11122543
57482590	57482613	5	+	28162770	EOL1	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.18271319508960704	[641]	[297]	-1	hSpCas9	negative selection	11291900
57481782	57481805	5	-	28162770	EOL1	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.44181588097261976	[543]	[210]	-3	hSpCas9	negative selection	11291901
57482533	57482556	5	-	28162770	EOL1	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	-0.848358703664785	[1137]	[332]	-5	hSpCas9	negative selection	11291902
57482479	57482502	5	-	28162770	EOL1	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.8609477165233299	[130]	[37]	-6	hSpCas9	negative selection	11291903
57482383	57482406	5	-	28162770	EOL1	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	-0.15571552229070607	[1773]	[838]	-1	hSpCas9	negative selection	11291904
57482374	57482397	5	+	28162770	EOL1	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	0.5547911515925571	[229]	[177]	5	hSpCas9	negative selection	11291905
57482245	57482268	5	-	28162770	EOL1	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.04067382868698799	[512]	[277]	0	hSpCas9	negative selection	11291906
57482174	57482197	5	+	28162770	EOL1	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	-0.1478030726541495	[367]	[174]	-1	hSpCas9	negative selection	11291907
57482078	57482101	5	+	28162770	EOL1	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.4088837139697912	[944]	[660]	4	hSpCas9	negative selection	11291908
57482041	57482064	5	-	28162770	EOL1	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.6277731539115106	[397]	[323]	5	hSpCas9	negative selection	11291909
57482590	57482613	5	+	28162770	MOLM13	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	0.9715122548137964	[528]	[749]	7	hSpCas9	negative selection	11461266
57481782	57481805	5	-	28162770	MOLM13	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.6713091042654702	[510]	[231]	-4	hSpCas9	negative selection	11461267
57482533	57482556	5	-	28162770	MOLM13	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.3093521579224472	[835]	[748]	2	hSpCas9	negative selection	11461268
57482479	57482502	5	-	28162770	MOLM13	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	1.21296002534784	[70]	[118]	8	hSpCas9	negative selection	11461269
57482383	57482406	5	-	28162770	MOLM13	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.3833830855756073	[1370]	[1292]	3	hSpCas9	negative selection	11461270
57482374	57482397	5	+	28162770	MOLM13	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	1.09174089565933	[182]	[281]	8	hSpCas9	negative selection	11461271
57482245	57482268	5	-	28162770	MOLM13	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	-0.21170999331465268	[566]	[353]	-1	hSpCas9	negative selection	11461272
57482174	57482197	5	+	28162770	MOLM13	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.14981361215282296	[373]	[299]	1	hSpCas9	negative selection	11461273
57482078	57482101	5	+	28162770	MOLM13	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.36950020898816893	[1167]	[1090]	2	hSpCas9	negative selection	11461274
57482041	57482064	5	-	28162770	MOLM13	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	-0.018208622674702024	[429]	[306]	0	hSpCas9	negative selection	11461275
57482590	57482613	5	+	28162770	HEL	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	0.8442185673175144	[406]	[467]	7	hSpCas9	negative selection	11630632
57481782	57481805	5	-	28162770	HEL	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.43992882566947766	[412]	[194]	-3	hSpCas9	negative selection	11630633
57482533	57482556	5	-	28162770	HEL	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.18257195723185338	[735]	[534]	1	hSpCas9	negative selection	11630634
57482479	57482502	5	-	28162770	HEL	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	1.5931568031497967	[73]	[142]	9	hSpCas9	negative selection	11630635
57482383	57482406	5	-	28162770	HEL	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.3061936410408128	[1239]	[981]	2	hSpCas9	negative selection	11630636
57482374	57482397	5	+	28162770	HEL	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	1.1701503101593547	[178]	[257]	8	hSpCas9	negative selection	11630637
57482245	57482268	5	-	28162770	HEL	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.1387504098117649	[484]	[341]	1	hSpCas9	negative selection	11630638
57482174	57482197	5	+	28162770	HEL	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.7082279135886163	[322]	[337]	6	hSpCas9	negative selection	11630639
57482078	57482101	5	+	28162770	HEL	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.35619083166567655	[865]	[709]	3	hSpCas9	negative selection	11630640
57482041	57482064	5	-	28162770	HEL	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	1.2464378953030988	[305]	[464]	9	hSpCas9	negative selection	11630641
57482590	57482613	5	+	28162770	MV411	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	0.27471048093287886	[261]	[266]	2	hSpCas9	negative selection	11799998
57481782	57481805	5	-	28162770	MV411	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.0381291432087969	[310]	[268]	0	hSpCas9	negative selection	11799999
57482533	57482556	5	-	28162770	MV411	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.6777741864445015	[468]	[631]	6	hSpCas9	negative selection	11800000
57482479	57482502	5	-	28162770	MV411	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.7873278673779012	[83]	[40]	-5	hSpCas9	negative selection	11800001
57482383	57482406	5	-	28162770	MV411	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.08243022523065102	[841]	[750]	0	hSpCas9	negative selection	11800002
57482374	57482397	5	+	28162770	MV411	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	-0.03267036840995996	[135]	[111]	0	hSpCas9	negative selection	11800003
57482245	57482268	5	-	28162770	MV411	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.46458951942334314	[393]	[457]	4	hSpCas9	negative selection	11800004
57482174	57482197	5	+	28162770	MV411	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.7660976811357765	[281]	[403]	7	hSpCas9	negative selection	11800005
57482078	57482101	5	+	28162770	MV411	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.7244847123370441	[591]	[823]	6	hSpCas9	negative selection	11800006
57482041	57482064	5	-	28162770	MV411	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.4633068485378886	[284]	[330]	4	hSpCas9	negative selection	11800007
57482590	57482613	5	+	28162770	MONOMAC1	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	0.3719841097925809	[181]	[269]	3	hSpCas9	negative selection	11969364
57481782	57481805	5	-	28162770	MONOMAC1	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.2847049333028322	[279]	[390]	3	hSpCas9	negative selection	11969365
57482533	57482556	5	-	28162770	MONOMAC1	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	-0.173246283724803	[420]	[427]	-1	hSpCas9	negative selection	11969366
57482479	57482502	5	-	28162770	MONOMAC1	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	-0.6476982560691187	[40]	[29]	-5	hSpCas9	negative selection	11969367
57482383	57482406	5	-	28162770	MONOMAC1	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.01957322168288833	[499]	[580]	0	hSpCas9	negative selection	11969368
57482374	57482397	5	+	28162770	MONOMAC1	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	-0.8278030373938348	[95]	[61]	-6	hSpCas9	negative selection	11969369
57482245	57482268	5	-	28162770	MONOMAC1	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.10935039693203064	[223]	[276]	1	hSpCas9	negative selection	11969370
57482174	57482197	5	+	28162770	MONOMAC1	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.7076152763529653	[171]	[321]	6	hSpCas9	negative selection	11969371
57482078	57482101	5	+	28162770	MONOMAC1	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	-0.040209834486156115	[417]	[465]	0	hSpCas9	negative selection	11969372
57482041	57482064	5	-	28162770	MONOMAC1	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.9128103337875155	[157]	[340]	8	hSpCas9	negative selection	11969373
57482590	57482613	5	+	28162770	OCIAML2	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.054138728821818694	[61]	[330]	0	hSpCas9	negative selection	12138730
57481782	57481805	5	-	28162770	OCIAML2	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	-0.05420578569235479	[64]	[346]	0	hSpCas9	negative selection	12138731
57482533	57482556	5	-	28162770	OCIAML2	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	-0.27402278114734346	[124]	[572]	-2	hSpCas9	negative selection	12138732
57482479	57482502	5	-	28162770	OCIAML2	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.23986355756285405	[10]	[71]	2	hSpCas9	negative selection	12138733
57482383	57482406	5	-	28162770	OCIAML2	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.33436775145289666	[174]	[1222]	3	hSpCas9	negative selection	12138734
57482374	57482397	5	+	28162770	OCIAML2	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	1.9337604298371742	[16]	[359]	9	hSpCas9	negative selection	12138735
57482245	57482268	5	-	28162770	OCIAML2	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.39561878586901167	[71]	[524]	4	hSpCas9	negative selection	12138736
57482174	57482197	5	+	28162770	OCIAML2	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	0.9820602155160809	[38]	[426]	8	hSpCas9	negative selection	12138737
57482078	57482101	5	+	28162770	OCIAML2	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.9314686183291843	[97]	[1035]	8	hSpCas9	negative selection	12138738
57482041	57482064	5	-	28162770	OCIAML2	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	0.29988832863507164	[50]	[347]	3	hSpCas9	negative selection	12138739
57482590	57482613	5	+	28162770	OCIAML3	viability	GAGGACGCCCTATCATGGAGGGG	ACTBL2	ENSG00000169067	-0.6703585264542781	[96]	[183]	-5	hSpCas9	negative selection	12308096
57481782	57481805	5	-	28162770	OCIAML3	viability	GGAGGGAGCACCATGTACCCAGG	ACTBL2	ENSG00000169067	0.21666764002505245	[123]	[434]	2	hSpCas9	negative selection	12308097
57482533	57482556	5	-	28162770	OCIAML3	viability	GGACTGCTACGTGGGAGATGAGG	ACTBL2	ENSG00000169067	0.38090137871300644	[144]	[569]	3	hSpCas9	negative selection	12308098
57482479	57482502	5	-	28162770	OCIAML3	viability	GTATCCTATCGAGCATGGAGTGG	ACTBL2	ENSG00000169067	0.33199177823205994	[24]	[94]	3	hSpCas9	negative selection	12308099
57482383	57482406	5	-	28162770	OCIAML3	viability	GCATCCCATCCTCCTCACCGAGG	ACTBL2	ENSG00000169067	0.34167137870898	[257]	[986]	3	hSpCas9	negative selection	12308100
57482374	57482397	5	+	28162770	OCIAML3	viability	TCAGGGGTGCCTCGGTGAGGAGG	ACTBL2	ENSG00000169067	0.4129117736156273	[51]	[208]	4	hSpCas9	negative selection	12308101
57482245	57482268	5	-	28162770	OCIAML3	viability	ACGGACCACAGGCATCGTGATGG	ACTBL2	ENSG00000169067	0.1800595806341403	[118]	[406]	1	hSpCas9	negative selection	12308102
57482174	57482197	5	+	28162770	OCIAML3	viability	GCGTAGAATGGCATGAGGCAGGG	ACTBL2	ENSG00000169067	1.11776962175121	[77]	[510]	8	hSpCas9	negative selection	12308103
57482078	57482101	5	+	28162770	OCIAML3	viability	CACAATCTCCCGCTCAGCAGTGG	ACTBL2	ENSG00000169067	0.4714367125772212	[166]	[698]	4	hSpCas9	negative selection	12308104
57482041	57482064	5	-	28162770	OCIAML3	viability	GAAGCTGTGCTACGTAGCCCTGG	ACTBL2	ENSG00000169067	-0.1330338568784606	[84]	[233]	-1	hSpCas9	negative selection	12308105