Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:86
• Symbol:ACTL6A
• Description:actin like 6A

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTL6A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
179586571	179586594	3	+	26472758	Jiyoye	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-3.680287459744466	[16]	[0]	-9	hSpCas9	negative selection	2071
179570091	179570114	3	+	26472758	Jiyoye	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.599879376028077	[409]	[101]	-8	hSpCas9	negative selection	2072
179576272	179576295	3	+	26472758	Jiyoye	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-2.857527844688539	[172]	[17]	-9	hSpCas9	negative selection	2073
179581173	179581196	3	+	26472758	Jiyoye	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-3.6225719618881786	[538]	[32]	-9	hSpCas9	negative selection	2074
179570136	179570159	3	+	26472758	Jiyoye	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	2075
179573446	179573469	3	-	26472758	Jiyoye	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-4.592824618494126	[223]	[6]	-9	hSpCas9	negative selection	2076
179574430	179574453	3	-	26472758	Jiyoye	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-0.03643126996974133	[33]	[24]	0	hSpCas9	negative selection	2077
179576634	179576657	3	-	26472758	Jiyoye	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	0.39539821372951983	[122]	[121]	3	hSpCas9	negative selection	2078
179580961	179580984	3	+	26472758	Jiyoye	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.94332186557826	[101]	[9]	-9	hSpCas9	negative selection	2079
179586571	179586594	3	+	26472758	KBM7	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-1.9696845450764275	[127,160]	[33,2]	-8	hSpCas9	negative selection	193189
179570091	179570114	3	+	26472758	KBM7	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-0.4986569709307189	[1871,1097]	[654,329]	-4	hSpCas9	negative selection	193190
179576272	179576295	3	+	26472758	KBM7	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-2.6680726071827023	[583,545]	[53,30]	-9	hSpCas9	negative selection	193191
179581173	179581196	3	+	26472758	KBM7	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.0569551514432967	[1810,1439]	[395,336]	-7	hSpCas9	negative selection	193192
179570136	179570159	3	+	26472758	KBM7	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.7094733166264073	[58,57]	[18,14]	-5	hSpCas9	negative selection	193193
179573446	179573469	3	-	26472758	KBM7	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-3.377501208715495	[766,799]	[31,38]	-9	hSpCas9	negative selection	193194
179574430	179574453	3	-	26472758	KBM7	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	0.6598915631760659	[212,246]	[59,273]	7	hSpCas9	negative selection	193195
179576634	179576657	3	-	26472758	KBM7	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-0.5468514997621003	[680,428]	[215,138]	-5	hSpCas9	negative selection	193196
179580961	179580984	3	+	26472758	KBM7	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.408790022589856	[295,231]	[19,69]	-7	hSpCas9	negative selection	193197
179586571	179586594	3	+	26472758	Raji	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-2.26185027429212	[61]	[2]	-9	hSpCas9	negative selection	384307
179570091	179570114	3	+	26472758	Raji	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.420219585905277	[714]	[61]	-7	hSpCas9	negative selection	384308
179576272	179576295	3	+	26472758	Raji	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-0.8796774089189026	[221]	[27]	-6	hSpCas9	negative selection	384309
179581173	179581196	3	+	26472758	Raji	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.7812448538421908	[784]	[52]	-8	hSpCas9	negative selection	384310
179570136	179570159	3	+	26472758	Raji	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-2.846812775013276	[30]	[0]	-9	hSpCas9	negative selection	384311
179573446	179573469	3	-	26472758	Raji	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-1.794436070687497	[283]	[18]	-8	hSpCas9	negative selection	384312
179574430	179574453	3	-	26472758	Raji	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-3.2024717272131884	[118]	[2]	-9	hSpCas9	negative selection	384313
179576634	179576657	3	-	26472758	Raji	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-2.1987772436554467	[454]	[22]	-8	hSpCas9	negative selection	384314
179580961	179580984	3	+	26472758	Raji	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-0.7467655981629457	[187]	[25]	-5	hSpCas9	negative selection	384315
179586571	179586594	3	+	26472758	K562	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-2.662471867942071	[104]	[13]	-8	hSpCas9	negative selection	575425
179570091	179570114	3	+	26472758	K562	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-0.21816812314568335	[1315]	[954]	-1	hSpCas9	negative selection	575426
179576272	179576295	3	+	26472758	K562	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-8.594785060430496	[457]	[0]	-9	hSpCas9	negative selection	575427
179581173	179581196	3	+	26472758	K562	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-2.935922889721204	[1250]	[137]	-8	hSpCas9	negative selection	575428
179570136	179570159	3	+	26472758	K562	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	1.130462538369361	[78]	[145]	8	hSpCas9	negative selection	575429
179573446	179573469	3	-	26472758	K562	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-6.645541471992194	[592]	[4]	-9	hSpCas9	negative selection	575430
179574430	179574453	3	-	26472758	K562	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	0.43262246282706807	[243]	[277]	3	hSpCas9	negative selection	575431
179576634	179576657	3	-	26472758	K562	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-0.8844587910678895	[666]	[304]	-5	hSpCas9	negative selection	575432
179580961	179580984	3	+	26472758	K562	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.3276624817579772	[222]	[74]	-6	hSpCas9	negative selection	575433
179569853	179569876	3	+	26627737	DLD1	viability	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-1.5163802939729623	[254]	[17,2,56]	-8	hSpCas9	negative selection	820539
179570136	179570159	3	+	26627737	DLD1	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	0.26339234915442655	[264]	[70,113,111]	2	hSpCas9	negative selection	820540
179570180	179570203	3	+	26627737	DLD1	viability	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-2.2826469199619606	[102]	[6,12,0]	-9	hSpCas9	negative selection	820541
179576281	179576304	3	-	26627737	DLD1	viability	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-2.0454331036357214	[467]	[61,12,30]	-9	hSpCas9	negative selection	820542
179576290	179576313	3	+	26627737	DLD1	viability	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-5.105279441699135	[308]	[1,0,4]	-9	hSpCas9	negative selection	820543
179580961	179580984	3	+	26627737	DLD1	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-0.6210516324953019	[66]	[0,0,34]	-6	hSpCas9	negative selection	820544
179569853	179569876	3	+	26627737	GBM cells	viability after 5 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-2.006226938772873	[205]	[35,18]	-9	hSpCas9	negative selection	902854
179570136	179570159	3	+	26627737	GBM cells	viability after 5 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.6757802903816434	[209]	[56,83]	-8	hSpCas9	negative selection	902855
179570180	179570203	3	+	26627737	GBM cells	viability after 5 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	0.14283945777177465	[37]	[18,25]	2	hSpCas9	negative selection	902856
179576281	179576304	3	-	26627737	GBM cells	viability after 5 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	0.8345928939188291	[171]	[164,163]	9	hSpCas9	negative selection	902857
179576290	179576313	3	+	26627737	GBM cells	viability after 5 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.2692088839226412	[199]	[63,24]	-9	hSpCas9	negative selection	902858
179580961	179580984	3	+	26627737	GBM cells	viability after 5 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-0.25111156911892163	[80]	[23,48]	-4	hSpCas9	negative selection	902859
179569853	179569876	3	+	26627737	GBM cells	viability after 13 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-1.6958729468266018	[205]	[71,3]	-9	hSpCas9	negative selection	985169
179570136	179570159	3	+	26627737	GBM cells	viability after 13 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.7093905128699853	[209]	[56,79]	-7	hSpCas9	negative selection	985170
179570180	179570203	3	+	26627737	GBM cells	viability after 13 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-0.19060508875331283	[37]	[11,22]	-2	hSpCas9	negative selection	985171
179576281	179576304	3	-	26627737	GBM cells	viability after 13 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	0.0813323493235601	[171]	[122,78]	1	hSpCas9	negative selection	985172
179576290	179576313	3	+	26627737	GBM cells	viability after 13 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.470108341885467	[199]	[31,44]	-9	hSpCas9	negative selection	985173
179580961	179580984	3	+	26627737	GBM cells	viability after 13 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.6934606791404594	[80]	[8,4]	-9	hSpCas9	negative selection	985174
179569853	179569876	3	+	26627737	GBM cells	viability after 21 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-5.242837888396045	[205]	[3,1]	-9	hSpCas9	negative selection	1067484
179570136	179570159	3	+	26627737	GBM cells	viability after 21 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	0.00098545907626868	[209]	[121,106]	0	hSpCas9	negative selection	1067485
179570180	179570203	3	+	26627737	GBM cells	viability after 21 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-2.367694213827927	[37]	[3,3]	-9	hSpCas9	negative selection	1067486
179576281	179576304	3	-	26627737	GBM cells	viability after 21 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-0.2327452870993788	[171]	[78,79]	-2	hSpCas9	negative selection	1067487
179576290	179576313	3	+	26627737	GBM cells	viability after 21 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-3.006362533775013	[199]	[12,13]	-9	hSpCas9	negative selection	1067488
179580961	179580984	3	+	26627737	GBM cells	viability after 21 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-5.459616703268966	[80]	[0,0]	-9	hSpCas9	negative selection	1067489
179569853	179569876	3	+	26627737	RPE1	viability after 9 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-6.971687251202945	[750]	[0,2]	-9	hSpCas9	negative selection	1149799
179570136	179570159	3	+	26627737	RPE1	viability after 9 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.3000582926327715	[1000]	[104,155]	-7	hSpCas9	negative selection	1149800
179570180	179570203	3	+	26627737	RPE1	viability after 9 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-2.0782133836523786	[454]	[55,4]	-8	hSpCas9	negative selection	1149801
179576281	179576304	3	-	26627737	RPE1	viability after 9 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-0.2660978829246141	[654]	[149,196]	-2	hSpCas9	negative selection	1149802
179576290	179576313	3	+	26627737	RPE1	viability after 9 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	0.26153101331770334	[174]	[28,112]	1	hSpCas9	negative selection	1149803
179580961	179580984	3	+	26627737	RPE1	viability after 9 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.500440726653653	[180]	[16,0]	-9	hSpCas9	negative selection	1149804
179569853	179569876	3	+	26627737	RPE1	viability after 12 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-4.4459906999014756	[750]	[0,17]	-9	hSpCas9	negative selection	1232114
179570136	179570159	3	+	26627737	RPE1	viability after 12 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.5879900709691523	[1000]	[87,90]	-8	hSpCas9	negative selection	1232115
179570180	179570203	3	+	26627737	RPE1	viability after 12 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-3.1410534032833977	[454]	[25,0]	-9	hSpCas9	negative selection	1232116
179576281	179576304	3	-	26627737	RPE1	viability after 12 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-0.6559388324073505	[654]	[83,140]	-4	hSpCas9	negative selection	1232117
179576290	179576313	3	+	26627737	RPE1	viability after 12 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.5044736270892232	[174]	[1,31]	-7	hSpCas9	negative selection	1232118
179580961	179580984	3	+	26627737	RPE1	viability after 12 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.249201715090778	[180]	[0,19]	-8	hSpCas9	negative selection	1232119
179569853	179569876	3	+	26627737	RPE1	viability after 15 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-7.730920223642378	[750]	[0,0]	-9	hSpCas9	negative selection	1314429
179570136	179570159	3	+	26627737	RPE1	viability after 15 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.0731659001640477	[1000]	[101,165]	-6	hSpCas9	negative selection	1314430
179570180	179570203	3	+	26627737	RPE1	viability after 15 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-2.282642306799543	[454]	[0,50]	-8	hSpCas9	negative selection	1314431
179576281	179576304	3	-	26627737	RPE1	viability after 15 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.6810903661281658	[654]	[41,72]	-7	hSpCas9	negative selection	1314432
179576290	179576313	3	+	26627737	RPE1	viability after 15 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-2.029347512006731	[174]	[4,18]	-8	hSpCas9	negative selection	1314433
179580961	179580984	3	+	26627737	RPE1	viability after 15 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-5.678097013211311	[180]	[0,0]	-9	hSpCas9	negative selection	1314434
179569853	179569876	3	+	26627737	RPE1	viability after 18 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-3.2144881435165034	[750]	[16,26]	-9	hSpCas9	negative selection	1396744
179570136	179570159	3	+	26627737	RPE1	viability after 18 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.1440211589144689	[1000]	[99,145]	-6	hSpCas9	negative selection	1396745
179570180	179570203	3	+	26627737	RPE1	viability after 18 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-3.2301784911044322	[454]	[0,25]	-9	hSpCas9	negative selection	1396746
179576281	179576304	3	-	26627737	RPE1	viability after 18 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.5574254049516456	[654]	[17,104]	-7	hSpCas9	negative selection	1396747
179576290	179576313	3	+	26627737	RPE1	viability after 18 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.7907889441090967	[174]	[17,8]	-8	hSpCas9	negative selection	1396748
179580961	179580984	3	+	26627737	RPE1	viability after 18 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-5.610177626982463	[180]	[0,0]	-9	hSpCas9	negative selection	1396749
179569853	179569876	3	+	26627737	HeLa	viability after 8 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-0.42290662193273065	[160]	[11,84,50]	-4	hSpCas9	negative selection	1479059
179570136	179570159	3	+	26627737	HeLa	viability after 8 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.7894634830567616	[491]	[271,49,84]	-7	hSpCas9	negative selection	1479060
179570180	179570203	3	+	26627737	HeLa	viability after 8 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	0.11439214412308596	[56]	[40,5,35]	1	hSpCas9	negative selection	1479061
179576281	179576304	3	-	26627737	HeLa	viability after 8 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-0.21773580599739134	[403]	[239,169,68]	-2	hSpCas9	negative selection	1479062
179576290	179576313	3	+	26627737	HeLa	viability after 8 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-0.845895922258809	[377]	[113,51,111]	-7	hSpCas9	negative selection	1479063
179580961	179580984	3	+	26627737	HeLa	viability after 8 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-0.38664862439692005	[120]	[47,70,5]	-4	hSpCas9	negative selection	1479064
179569853	179569876	3	+	26627737	HeLa	viability after 12 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-5.095052635223421	[160]	[3,0,0]	-9	hSpCas9	negative selection	1561374
179570136	179570159	3	+	26627737	HeLa	viability after 12 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.6140383869840544	[491]	[261,78,66]	-5	hSpCas9	negative selection	1561375
179570180	179570203	3	+	26627737	HeLa	viability after 12 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-1.4689547080014713	[56]	[0,1,22]	-8	hSpCas9	negative selection	1561376
179576281	179576304	3	-	26627737	HeLa	viability after 12 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	0.3696173830814891	[403]	[421,216,13]	3	hSpCas9	negative selection	1561377
179576290	179576313	3	+	26627737	HeLa	viability after 12 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-2.566562608553723	[377]	[51,24,2]	-9	hSpCas9	negative selection	1561378
179580961	179580984	3	+	26627737	HeLa	viability after 12 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-0.9784987191359837	[120]	[7,2,66]	-7	hSpCas9	negative selection	1561379
179569853	179569876	3	+	26627737	HeLa	viability after 15 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-1.6991715067695923	[160]	[26,30,0]	-9	hSpCas9	negative selection	1643689
179570136	179570159	3	+	26627737	HeLa	viability after 15 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.0868889554601837	[491]	[107,100,71]	-7	hSpCas9	negative selection	1643690
179570180	179570203	3	+	26627737	HeLa	viability after 15 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-0.9887531902168649	[56]	[0,0,34]	-7	hSpCas9	negative selection	1643691
179576281	179576304	3	-	26627737	HeLa	viability after 15 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	0.1504759994568573	[403]	[341,148,43]	1	hSpCas9	negative selection	1643692
179576290	179576313	3	+	26627737	HeLa	viability after 15 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.9234730491128682	[377]	[91,0,26]	-9	hSpCas9	negative selection	1643693
179580961	179580984	3	+	26627737	HeLa	viability after 15 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.2691482326825927	[120]	[12,44,1]	-8	hSpCas9	negative selection	1643694
179569853	179569876	3	+	26627737	HeLa	viability after 18 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-1.6433540883718085	[160]	[20,23,0]	-8	hSpCas9	negative selection	1726004
179570136	179570159	3	+	26627737	HeLa	viability after 18 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.0555255260688325	[491]	[72,87,71]	-7	hSpCas9	negative selection	1726005
179570180	179570203	3	+	26627737	HeLa	viability after 18 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-0.9594561089847566	[56]	[0,0,34]	-7	hSpCas9	negative selection	1726006
179576281	179576304	3	-	26627737	HeLa	viability after 18 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	0.16272792009553916	[403]	[235,118,43]	1	hSpCas9	negative selection	1726007
179576290	179576313	3	+	26627737	HeLa	viability after 18 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.9160228477804364	[377]	[61,0,26]	-9	hSpCas9	negative selection	1726008
179580961	179580984	3	+	26627737	HeLa	viability after 18 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.1551596614767998	[120]	[8,40,1]	-7	hSpCas9	negative selection	1726009
179569853	179569876	3	+	26627737	HCT116	viability after 6 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-5.330778518856717	[528]	[3,0]	-9	hSpCas9	negative selection	1808319
179570136	179570159	3	+	26627737	HCT116	viability after 6 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	0.2207106852705671	[450]	[90,77]	1	hSpCas9	negative selection	1808320
179570180	179570203	3	+	26627737	HCT116	viability after 6 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-1.922972336872503	[296]	[1,17]	-8	hSpCas9	negative selection	1808321
179576281	179576304	3	-	26627737	HCT116	viability after 6 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	1.7238834618622723	[344]	[445,31]	8	hSpCas9	negative selection	1808322
179576290	179576313	3	+	26627737	HCT116	viability after 6 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.730486877782208	[500]	[15,27]	-7	hSpCas9	negative selection	1808323
179580961	179580984	3	+	26627737	HCT116	viability after 6 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	0.18590347854075517	[100]	[48,0]	1	hSpCas9	negative selection	1808324
179569853	179569876	3	+	26627737	HCT116	viability after 8 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-1.4179968206894111	[161]	[24,35,38]	-9	hSpCas9	negative selection	1890634
179570136	179570159	3	+	26627737	HCT116	viability after 8 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.0697819222447844	[197]	[53,52,48]	-8	hSpCas9	negative selection	1890635
179570180	179570203	3	+	26627737	HCT116	viability after 8 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-1.6363081872984815	[118]	[14,12,34]	-9	hSpCas9	negative selection	1890636
179576281	179576304	3	-	26627737	HCT116	viability after 8 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-0.961382320650839	[386]	[141,66,119]	-8	hSpCas9	negative selection	1890637
179576290	179576313	3	+	26627737	HCT116	viability after 8 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.4503830985800208	[243]	[70,28,47]	-9	hSpCas9	negative selection	1890638
179580961	179580984	3	+	26627737	HCT116	viability after 8 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.5967705146930715	[87]	[9,22,14]	-9	hSpCas9	negative selection	1890639
179569853	179569876	3	+	26627737	HCT116	viability after 9 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-4.334779178702953	[528]	[6,6]	-9	hSpCas9	negative selection	1972949
179570136	179570159	3	+	26627737	HCT116	viability after 9 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.9111817122233401	[450]	[15,101]	-6	hSpCas9	negative selection	1972950
179570180	179570203	3	+	26627737	HCT116	viability after 9 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-1.3920782022330571	[296]	[51,12]	-7	hSpCas9	negative selection	1972951
179576281	179576304	3	-	26627737	HCT116	viability after 9 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	0.2541235310213774	[344]	[72,138]	2	hSpCas9	negative selection	1972952
179576290	179576313	3	+	26627737	HCT116	viability after 9 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-3.4434076123846307	[500]	[18,6]	-9	hSpCas9	negative selection	1972953
179580961	179580984	3	+	26627737	HCT116	viability after 9 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	1.3460432006424756	[100]	[67,68]	8	hSpCas9	negative selection	1972954
179569853	179569876	3	+	26627737	HCT116	viability after 12 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-1.917644947929098	[161]	[21,36,8]	-9	hSpCas9	negative selection	2055264
179570136	179570159	3	+	26627737	HCT116	viability after 12 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.5181335355670973	[197]	[97,82,34]	-5	hSpCas9	negative selection	2055265
179570180	179570203	3	+	26627737	HCT116	viability after 12 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-2.156666501237308	[118]	[25,12,1]	-9	hSpCas9	negative selection	2055266
179576281	179576304	3	-	26627737	HCT116	viability after 12 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.557369078435525	[386]	[59,105,42]	-9	hSpCas9	negative selection	2055267
179576290	179576313	3	+	26627737	HCT116	viability after 12 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.9294551993483506	[243]	[41,22,34]	-9	hSpCas9	negative selection	2055268
179580961	179580984	3	+	26627737	HCT116	viability after 12 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.9084960882113324	[87]	[0,8,8]	-9	hSpCas9	negative selection	2055269
179569853	179569876	3	+	26627737	HCT116	viability after 15 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-3.888313676599802	[161]	[6,10,0]	-9	hSpCas9	negative selection	2137579
179570136	179570159	3	+	26627737	HCT116	viability after 15 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.33601685611645415	[197]	[182,44,53]	-3	hSpCas9	negative selection	2137580
179570180	179570203	3	+	26627737	HCT116	viability after 15 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-1.630846858853751	[118]	[18,38,7]	-9	hSpCas9	negative selection	2137581
179576281	179576304	3	-	26627737	HCT116	viability after 15 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.2983321884240182	[386]	[86,118,64]	-8	hSpCas9	negative selection	2137582
179576290	179576313	3	+	26627737	HCT116	viability after 15 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-3.1707668549498638	[243]	[9,19,15]	-9	hSpCas9	negative selection	2137583
179580961	179580984	3	+	26627737	HCT116	viability after 15 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-3.7327496812562404	[87]	[0,0,8]	-9	hSpCas9	negative selection	2137584
179569853	179569876	3	+	26627737	HCT116	viability after 18 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-3.6986031340481773	[161]	[12,3,0]	-9	hSpCas9	negative selection	2219894
179570136	179570159	3	+	26627737	HCT116	viability after 18 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.3814269728335502	[197]	[127,54,36]	-4	hSpCas9	negative selection	2219895
179570180	179570203	3	+	26627737	HCT116	viability after 18 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-1.8142932164583898	[118]	[7,28,10]	-8	hSpCas9	negative selection	2219896
179576281	179576304	3	-	26627737	HCT116	viability after 18 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.6319935281958629	[386]	[49,73,55]	-8	hSpCas9	negative selection	2219897
179576290	179576313	3	+	26627737	HCT116	viability after 18 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-2.7980225485183987	[243]	[11,17,20]	-9	hSpCas9	negative selection	2219898
179580961	179580984	3	+	26627737	HCT116	viability after 18 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.9715877162715283	[87]	[0,0,14]	-9	hSpCas9	negative selection	2219899
179570091	179570114	3	+	24336569	HL60	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-2.2452889025347913	[353]	[157]	-9	hSpCas9	negative selection	2246423
179570105	179570128	3	+	24336569	HL60	viability	AGATGACGGAAGCACATTAATGG	ACTL6A	ENSG00000136518	0.9867464777305356	[283]	[1190]	7	hSpCas9	negative selection	2246424
179570115	179570138	3	+	24336569	HL60	viability	AGCACATTAATGGAAATAGATGG	ACTL6A	ENSG00000136518	-0.1372619390636636	[513]	[988]	-1	hSpCas9	negative selection	2246425
179570124	179570147	3	+	24336569	HL60	viability	ATGGAAATAGATGGCGATAAAGG	ACTL6A	ENSG00000136518	0.07647601782400582	[872]	[1947]	0	hSpCas9	negative selection	2246426
179570133	179570156	3	+	24336569	HL60	viability	GATGGCGATAAAGGCAAACAAGG	ACTL6A	ENSG00000136518	0.14092832070755157	[818]	[1910]	1	hSpCas9	negative selection	2246427
179570160	179570183	3	-	24336569	HL60	viability	TTAGTATCTATGTAGTAGGTGGG	ACTL6A	ENSG00000136518	-0.8511664812071021	[259]	[304]	-6	hSpCas9	negative selection	2246428
179570179	179570202	3	+	24336569	HL60	viability	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-1.2924404778995906	[1006]	[869]	-8	hSpCas9	negative selection	2246429
179570189	179570212	3	+	24336569	HL60	viability	GCGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	2.089937559121339	[216]	[1954]	9	hSpCas9	negative selection	2246430
179570196	179570219	3	-	24336569	HL60	viability	ATGGCCTCCATATTCTCCCTCGG	ACTL6A	ENSG00000136518	-1.018864474271494	[450]	[470]	-7	hSpCas9	negative selection	2246431
179573357	179573380	3	+	24336569	HL60	viability	CTTATATTCTAGTTGAAGACTGG	ACTL6A	ENSG00000136518	-0.20596264274678178	[126]	[232]	-2	hSpCas9	negative selection	2246432
179570091	179570114	3	+	24336569	KBM7	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-0.8899671839726818	[283]	[417]	-6	hSpCas9	negative selection	2313600
179570105	179570128	3	+	24336569	KBM7	viability	AGATGACGGAAGCACATTAATGG	ACTL6A	ENSG00000136518	0.8659277306501003	[377]	[1878]	7	hSpCas9	negative selection	2313601
179570115	179570138	3	+	24336569	KBM7	viability	AGCACATTAATGGAAATAGATGG	ACTL6A	ENSG00000136518	-0.23056611187120857	[498]	[1159]	-2	hSpCas9	negative selection	2313602
179570124	179570147	3	+	24336569	KBM7	viability	ATGGAAATAGATGGCGATAAAGG	ACTL6A	ENSG00000136518	-0.52827179890796	[670]	[1268]	-4	hSpCas9	negative selection	2313603
179570133	179570156	3	+	24336569	KBM7	viability	GATGGCGATAAAGGCAAACAAGG	ACTL6A	ENSG00000136518	-0.11690746858954393	[657]	[1654]	-1	hSpCas9	negative selection	2313604
179570160	179570183	3	-	24336569	KBM7	viability	TTAGTATCTATGTAGTAGGTGGG	ACTL6A	ENSG00000136518	-1.9004381612626935	[218]	[159]	-8	hSpCas9	negative selection	2313605
179570179	179570202	3	+	24336569	KBM7	viability	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-1.877908347780317	[410]	[304]	-8	hSpCas9	negative selection	2313606
179570189	179570212	3	+	24336569	KBM7	viability	GCGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.5330972677349396	[555]	[1047]	-4	hSpCas9	negative selection	2313607
179570196	179570219	3	-	24336569	KBM7	viability	ATGGCCTCCATATTCTCCCTCGG	ACTL6A	ENSG00000136518	0.09409920644347392	[202]	[590]	0	hSpCas9	negative selection	2313608
179573357	179573380	3	+	24336569	KBM7	viability	CTTATATTCTAGTTGAAGACTGG	ACTL6A	ENSG00000136518	0.059591143566122606	[253]	[721]	0	hSpCas9	negative selection	2313609
179578377	179578400	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACATCCATCTCCTGG	ACTL6A	ENSG00000136518	0.22198336291758158	[1180,549]	[128,319]	1	dCas9-VP64	positive selection	2395498
179579542	179579565	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTTTGGGAGGCCAAGGCAGTGG	ACTL6A	ENSG00000136518	2.0119762381202047	[93,200]	[9,263]	7	dCas9-VP64	positive selection	2462481
179578377	179578400	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACATCCATCTCCTGG	ACTL6A	ENSG00000136518	-0.386497360481894	[313,478]	[113,83]	-4	dCas9-VP64	positive selection	2490753
179579542	179579565	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTTTGGGAGGCCAAGGCAGTGG	ACTL6A	ENSG00000136518	-0.4547686614086857	[146,265]	[55,41]	-5	dCas9-VP64	positive selection	2557736
179569867	179569890	3	+	27260157	DLD1	viability	GAGAGCTGGTTATGCTGGTGAGG	ACTL6A	ENSG00000136518	0.602616880196027	[]	[]	8	hSpCas9	negative selection	2574471
179570105	179570128	3	+	27260157	DLD1	viability	AGATGACGGAAGCACATTAATGG	ACTL6A	ENSG00000136518	-1.26854822062117	[]	[]	-7	hSpCas9	negative selection	2575718
179573435	179573458	3	-	27260157	DLD1	viability	CATGAGAACAGGATGGAGACTGG	ACTL6A	ENSG00000136518	-1.22917335345576	[]	[]	-7	hSpCas9	negative selection	2577622
179563113	179563136	3	+	27260157	DLD1	viability	GGGAGGTGAGTGAGTGCGGCCGG	ACTL6A	ENSG00000136518	-1.19674145060497	[]	[]	-7	hSpCas9	negative selection	2579050
179563090	179563113	3	+	27260157	DLD1	viability	GCCATGAGCGGCGGCGTGTACGG	ACTL6A	ENSG00000136518	-2.62780441796545	[]	[]	-9	hSpCas9	negative selection	2581339
179570075	179570098	3	+	27260157	DLD1	viability	TCCTACAGCTATTGGTATGGTGG	ACTL6A	ENSG00000136518	-3.01029977666763	[]	[]	-9	hSpCas9	negative selection	2581518
179570124	179570147	3	+	27260157	DLD1	viability	ATGGAAATAGATGGCGATAAAGG	ACTL6A	ENSG00000136518	-0.508235111261899	[]	[]	-4	hSpCas9	negative selection	2584876
179570160	179570183	3	-	27260157	DLD1	viability	TTAGTATCTATGTAGTAGGTGGG	ACTL6A	ENSG00000136518	-1.03978641266644	[]	[]	-7	hSpCas9	negative selection	2606446
179570091	179570114	3	+	27260157	DLD1	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-2.14478202888823	[]	[]	-9	hSpCas9	negative selection	2608535
179563078	179563101	3	+	27260157	DLD1	viability	GCGCCGGCAGCAGCCATGAGCGG	ACTL6A	ENSG00000136518	-5.00974551085326	[]	[]	-9	hSpCas9	negative selection	2610209
179570179	179570202	3	+	27260157	DLD1	viability	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-1.7845587405111	[]	[]	-8	hSpCas9	negative selection	2611183
179570076	179570099	3	-	27260157	DLD1	viability	ACCACCATACCAATAGCTGTAGG	ACTL6A	ENSG00000136518	-0.849061075184994	[]	[]	-6	hSpCas9	negative selection	2612552
179569853	179569876	3	+	27260157	DLD1	viability	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-2.69122285610253	[]	[]	-9	hSpCas9	negative selection	2617074
179570115	179570138	3	+	27260157	DLD1	viability	AGCACATTAATGGAAATAGATGG	ACTL6A	ENSG00000136518	-1.60589127187831	[]	[]	-8	hSpCas9	negative selection	2618395
179570189	179570212	3	+	27260157	DLD1	viability	GCGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.532215508026018	[]	[]	-4	hSpCas9	negative selection	2621288
179563091	179563114	3	-	27260157	DLD1	viability	CCCGTACACGCCGCCGCTCATGG	ACTL6A	ENSG00000136518	-5.52309489586374	[]	[]	-9	hSpCas9	negative selection	2641309
179570196	179570219	3	-	27260157	DLD1	viability	ATGGCCTCCATATTCTCCCTCGG	ACTL6A	ENSG00000136518	-0.666598440202909	[]	[]	-5	hSpCas9	negative selection	2642580
179563081	179563104	3	-	27260157	DLD1	viability	CCGCCGCTCATGGCTGCTGCCGG	ACTL6A	ENSG00000136518	0.639929455908218	[]	[]	8	hSpCas9	negative selection	2643777
179570133	179570156	3	+	27260157	DLD1	viability	GATGGCGATAAAGGCAAACAAGG	ACTL6A	ENSG00000136518	-0.363140218552294	[]	[]	-3	hSpCas9	negative selection	2644155
179569867	179569890	3	+	27260157	HT1080	viability	GAGAGCTGGTTATGCTGGTGAGG	ACTL6A	ENSG00000136518	-0.693512254866886	[]	[]	-8	hSpCas9	negative selection	2650601
179570105	179570128	3	+	27260157	HT1080	viability	AGATGACGGAAGCACATTAATGG	ACTL6A	ENSG00000136518	-1.9913706227801	[]	[]	-9	hSpCas9	negative selection	2651848
179573435	179573458	3	-	27260157	HT1080	viability	CATGAGAACAGGATGGAGACTGG	ACTL6A	ENSG00000136518	-1.25480382116247	[]	[]	-9	hSpCas9	negative selection	2653752
179563113	179563136	3	+	27260157	HT1080	viability	GGGAGGTGAGTGAGTGCGGCCGG	ACTL6A	ENSG00000136518	-0.629478934628773	[]	[]	-8	hSpCas9	negative selection	2655180
179563090	179563113	3	+	27260157	HT1080	viability	GCCATGAGCGGCGGCGTGTACGG	ACTL6A	ENSG00000136518	-2.43437923763631	[]	[]	-9	hSpCas9	negative selection	2657469
179570075	179570098	3	+	27260157	HT1080	viability	TCCTACAGCTATTGGTATGGTGG	ACTL6A	ENSG00000136518	-2.9819303478284	[]	[]	-9	hSpCas9	negative selection	2657648
179570124	179570147	3	+	27260157	HT1080	viability	ATGGAAATAGATGGCGATAAAGG	ACTL6A	ENSG00000136518	-0.371153660759298	[]	[]	-7	hSpCas9	negative selection	2661006
179570160	179570183	3	-	27260157	HT1080	viability	TTAGTATCTATGTAGTAGGTGGG	ACTL6A	ENSG00000136518	-1.42764208545573	[]	[]	-9	hSpCas9	negative selection	2682576
179570091	179570114	3	+	27260157	HT1080	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-2.23662821446926	[]	[]	-9	hSpCas9	negative selection	2684665
179563078	179563101	3	+	27260157	HT1080	viability	GCGCCGGCAGCAGCCATGAGCGG	ACTL6A	ENSG00000136518	-4.24998400642225	[]	[]	-9	hSpCas9	negative selection	2686339
179570179	179570202	3	+	27260157	HT1080	viability	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-1.92345342557355	[]	[]	-9	hSpCas9	negative selection	2687313
179570076	179570099	3	-	27260157	HT1080	viability	ACCACCATACCAATAGCTGTAGG	ACTL6A	ENSG00000136518	-1.72194594644707	[]	[]	-9	hSpCas9	negative selection	2688682
179569853	179569876	3	+	27260157	HT1080	viability	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-2.17764665498536	[]	[]	-9	hSpCas9	negative selection	2693204
179570115	179570138	3	+	27260157	HT1080	viability	AGCACATTAATGGAAATAGATGG	ACTL6A	ENSG00000136518	-0.88015966802382	[]	[]	-8	hSpCas9	negative selection	2694525
179570189	179570212	3	+	27260157	HT1080	viability	GCGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.0157435661171418	[]	[]	0	hSpCas9	negative selection	2697418
179563091	179563114	3	-	27260157	HT1080	viability	CCCGTACACGCCGCCGCTCATGG	ACTL6A	ENSG00000136518	-4.63438974716798	[]	[]	-9	hSpCas9	negative selection	2717439
179570196	179570219	3	-	27260157	HT1080	viability	ATGGCCTCCATATTCTCCCTCGG	ACTL6A	ENSG00000136518	-1.13594476433362	[]	[]	-8	hSpCas9	negative selection	2718710
179563081	179563104	3	-	27260157	HT1080	viability	CCGCCGCTCATGGCTGCTGCCGG	ACTL6A	ENSG00000136518	-0.722590365505755	[]	[]	-8	hSpCas9	negative selection	2719907
179570133	179570156	3	+	27260157	HT1080	viability	GATGGCGATAAAGGCAAACAAGG	ACTL6A	ENSG00000136518	-0.860204500602876	[]	[]	-8	hSpCas9	negative selection	2720285
179569867	179569890	3	+	27260157	MKN45	viability	GAGAGCTGGTTATGCTGGTGAGG	ACTL6A	ENSG00000136518	-0.994978289718036	[]	[]	-8	hSpCas9	negative selection	2726731
179570105	179570128	3	+	27260157	MKN45	viability	AGATGACGGAAGCACATTAATGG	ACTL6A	ENSG00000136518	-0.00948248530280698	[]	[]	0	hSpCas9	negative selection	2727978
179573435	179573458	3	-	27260157	MKN45	viability	CATGAGAACAGGATGGAGACTGG	ACTL6A	ENSG00000136518	-0.720363644297943	[]	[]	-7	hSpCas9	negative selection	2729882
179563113	179563136	3	+	27260157	MKN45	viability	GGGAGGTGAGTGAGTGCGGCCGG	ACTL6A	ENSG00000136518	-1.08010203496616	[]	[]	-8	hSpCas9	negative selection	2731310
179563090	179563113	3	+	27260157	MKN45	viability	GCCATGAGCGGCGGCGTGTACGG	ACTL6A	ENSG00000136518	-1.89075924624225	[]	[]	-9	hSpCas9	negative selection	2733599
179570075	179570098	3	+	27260157	MKN45	viability	TCCTACAGCTATTGGTATGGTGG	ACTL6A	ENSG00000136518	-2.79587191757421	[]	[]	-9	hSpCas9	negative selection	2733778
179570124	179570147	3	+	27260157	MKN45	viability	ATGGAAATAGATGGCGATAAAGG	ACTL6A	ENSG00000136518	0.0899778532631984	[]	[]	0	hSpCas9	negative selection	2737136
179570160	179570183	3	-	27260157	MKN45	viability	TTAGTATCTATGTAGTAGGTGGG	ACTL6A	ENSG00000136518	-1.47255215010234	[]	[]	-8	hSpCas9	negative selection	2758706
179570091	179570114	3	+	27260157	MKN45	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.50526461679829	[]	[]	-8	hSpCas9	negative selection	2760795
179563078	179563101	3	+	27260157	MKN45	viability	GCGCCGGCAGCAGCCATGAGCGG	ACTL6A	ENSG00000136518	-2.7784140355254	[]	[]	-9	hSpCas9	negative selection	2762469
179570179	179570202	3	+	27260157	MKN45	viability	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-2.35349999538445	[]	[]	-9	hSpCas9	negative selection	2763443
179570076	179570099	3	-	27260157	MKN45	viability	ACCACCATACCAATAGCTGTAGG	ACTL6A	ENSG00000136518	-0.200330501595917	[]	[]	0	hSpCas9	negative selection	2764812
179569853	179569876	3	+	27260157	MKN45	viability	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-2.46624085905849	[]	[]	-9	hSpCas9	negative selection	2769334
179570115	179570138	3	+	27260157	MKN45	viability	AGCACATTAATGGAAATAGATGG	ACTL6A	ENSG00000136518	-0.685329714392139	[]	[]	-7	hSpCas9	negative selection	2770655
179570189	179570212	3	+	27260157	MKN45	viability	GCGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.604619006275554	[]	[]	-6	hSpCas9	negative selection	2773548
179563091	179563114	3	-	27260157	MKN45	viability	CCCGTACACGCCGCCGCTCATGG	ACTL6A	ENSG00000136518	-3.7697978260273	[]	[]	-9	hSpCas9	negative selection	2793569
179570196	179570219	3	-	27260157	MKN45	viability	ATGGCCTCCATATTCTCCCTCGG	ACTL6A	ENSG00000136518	-1.33337174622592	[]	[]	-8	hSpCas9	negative selection	2794840
179563081	179563104	3	-	27260157	MKN45	viability	CCGCCGCTCATGGCTGCTGCCGG	ACTL6A	ENSG00000136518	-0.377665698413247	[]	[]	-1	hSpCas9	negative selection	2796037
179570133	179570156	3	+	27260157	MKN45	viability	GATGGCGATAAAGGCAAACAAGG	ACTL6A	ENSG00000136518	-0.767764326683774	[]	[]	-7	hSpCas9	negative selection	2796415
179569867	179569890	3	+	27260157	RKO	viability	GAGAGCTGGTTATGCTGGTGAGG	ACTL6A	ENSG00000136518	-0.221825069340743	[]	[]	-1	hSpCas9	negative selection	2802861
179570105	179570128	3	+	27260157	RKO	viability	AGATGACGGAAGCACATTAATGG	ACTL6A	ENSG00000136518	0.119769694779071	[]	[]	0	hSpCas9	negative selection	2804108
179573435	179573458	3	-	27260157	RKO	viability	CATGAGAACAGGATGGAGACTGG	ACTL6A	ENSG00000136518	-1.3626008187522	[]	[]	-8	hSpCas9	negative selection	2806012
179563113	179563136	3	+	27260157	RKO	viability	GGGAGGTGAGTGAGTGCGGCCGG	ACTL6A	ENSG00000136518	-1.50250576421733	[]	[]	-8	hSpCas9	negative selection	2807440
179563090	179563113	3	+	27260157	RKO	viability	GCCATGAGCGGCGGCGTGTACGG	ACTL6A	ENSG00000136518	-1.97301025431307	[]	[]	-9	hSpCas9	negative selection	2809729
179570075	179570098	3	+	27260157	RKO	viability	TCCTACAGCTATTGGTATGGTGG	ACTL6A	ENSG00000136518	-3.11115311539949	[]	[]	-9	hSpCas9	negative selection	2809908
179570124	179570147	3	+	27260157	RKO	viability	ATGGAAATAGATGGCGATAAAGG	ACTL6A	ENSG00000136518	-1.00532127742196	[]	[]	-8	hSpCas9	negative selection	2813266
179570160	179570183	3	-	27260157	RKO	viability	TTAGTATCTATGTAGTAGGTGGG	ACTL6A	ENSG00000136518	-2.14473940760558	[]	[]	-9	hSpCas9	negative selection	2834836
179570091	179570114	3	+	27260157	RKO	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.58768184347149	[]	[]	-9	hSpCas9	negative selection	2836925
179563078	179563101	3	+	27260157	RKO	viability	GCGCCGGCAGCAGCCATGAGCGG	ACTL6A	ENSG00000136518	-3.8019787481961	[]	[]	-9	hSpCas9	negative selection	2838599
179570179	179570202	3	+	27260157	RKO	viability	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-1.92422242125453	[]	[]	-9	hSpCas9	negative selection	2839573
179570076	179570099	3	-	27260157	RKO	viability	ACCACCATACCAATAGCTGTAGG	ACTL6A	ENSG00000136518	-1.24937411407492	[]	[]	-8	hSpCas9	negative selection	2840942
179569853	179569876	3	+	27260157	RKO	viability	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-2.58642619319042	[]	[]	-9	hSpCas9	negative selection	2845464
179570115	179570138	3	+	27260157	RKO	viability	AGCACATTAATGGAAATAGATGG	ACTL6A	ENSG00000136518	-1.09754478731935	[]	[]	-8	hSpCas9	negative selection	2846785
179570189	179570212	3	+	27260157	RKO	viability	GCGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.723366287330472	[]	[]	-7	hSpCas9	negative selection	2849678
179563091	179563114	3	-	27260157	RKO	viability	CCCGTACACGCCGCCGCTCATGG	ACTL6A	ENSG00000136518	-3.74574486371991	[]	[]	-9	hSpCas9	negative selection	2869699
179570196	179570219	3	-	27260157	RKO	viability	ATGGCCTCCATATTCTCCCTCGG	ACTL6A	ENSG00000136518	-1.11095750841587	[]	[]	-8	hSpCas9	negative selection	2870970
179563081	179563104	3	-	27260157	RKO	viability	CCGCCGCTCATGGCTGCTGCCGG	ACTL6A	ENSG00000136518	-0.406078483758626	[]	[]	-6	hSpCas9	negative selection	2872167
179570133	179570156	3	+	27260157	RKO	viability	GATGGCGATAAAGGCAAACAAGG	ACTL6A	ENSG00000136518	0.0606851791346348	[]	[]	0	hSpCas9	negative selection	2872545
179569867	179569890	3	+	27260157	SF268	viability	GAGAGCTGGTTATGCTGGTGAGG	ACTL6A	ENSG00000136518	-0.178371991625874	[]	[]	-1	hSpCas9	negative selection	2878991
179570105	179570128	3	+	27260157	SF268	viability	AGATGACGGAAGCACATTAATGG	ACTL6A	ENSG00000136518	-1.70826326973239	[]	[]	-8	hSpCas9	negative selection	2880238
179573435	179573458	3	-	27260157	SF268	viability	CATGAGAACAGGATGGAGACTGG	ACTL6A	ENSG00000136518	-2.72439348044724	[]	[]	-9	hSpCas9	negative selection	2882142
179563113	179563136	3	+	27260157	SF268	viability	GGGAGGTGAGTGAGTGCGGCCGG	ACTL6A	ENSG00000136518	-1.50249731319841	[]	[]	-8	hSpCas9	negative selection	2883570
179563090	179563113	3	+	27260157	SF268	viability	GCCATGAGCGGCGGCGTGTACGG	ACTL6A	ENSG00000136518	-3.08862742919681	[]	[]	-9	hSpCas9	negative selection	2885859
179570075	179570098	3	+	27260157	SF268	viability	TCCTACAGCTATTGGTATGGTGG	ACTL6A	ENSG00000136518	-2.9879179140039	[]	[]	-9	hSpCas9	negative selection	2886038
179570124	179570147	3	+	27260157	SF268	viability	ATGGAAATAGATGGCGATAAAGG	ACTL6A	ENSG00000136518	-0.855329716478671	[]	[]	-6	hSpCas9	negative selection	2889396
179570160	179570183	3	-	27260157	SF268	viability	TTAGTATCTATGTAGTAGGTGGG	ACTL6A	ENSG00000136518	-2.06814104145075	[]	[]	-9	hSpCas9	negative selection	2910966
179570091	179570114	3	+	27260157	SF268	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-2.98883208183597	[]	[]	-9	hSpCas9	negative selection	2913055
179563078	179563101	3	+	27260157	SF268	viability	GCGCCGGCAGCAGCCATGAGCGG	ACTL6A	ENSG00000136518	-4.00402426543248	[]	[]	-9	hSpCas9	negative selection	2914729
179570179	179570202	3	+	27260157	SF268	viability	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-3.05800192890704	[]	[]	-9	hSpCas9	negative selection	2915703
179570076	179570099	3	-	27260157	SF268	viability	ACCACCATACCAATAGCTGTAGG	ACTL6A	ENSG00000136518	-0.834743480134027	[]	[]	-6	hSpCas9	negative selection	2917072
179569853	179569876	3	+	27260157	SF268	viability	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-3.74153579367785	[]	[]	-9	hSpCas9	negative selection	2921594
179570115	179570138	3	+	27260157	SF268	viability	AGCACATTAATGGAAATAGATGG	ACTL6A	ENSG00000136518	-2.79191609852441	[]	[]	-9	hSpCas9	negative selection	2922915
179570189	179570212	3	+	27260157	SF268	viability	GCGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.0248250616971122	[]	[]	0	hSpCas9	negative selection	2925808
179563091	179563114	3	-	27260157	SF268	viability	CCCGTACACGCCGCCGCTCATGG	ACTL6A	ENSG00000136518	-4.53546999413439	[]	[]	-9	hSpCas9	negative selection	2945829
179570196	179570219	3	-	27260157	SF268	viability	ATGGCCTCCATATTCTCCCTCGG	ACTL6A	ENSG00000136518	-1.82137949499003	[]	[]	-8	hSpCas9	negative selection	2947100
179563081	179563104	3	-	27260157	SF268	viability	CCGCCGCTCATGGCTGCTGCCGG	ACTL6A	ENSG00000136518	-0.972364501574036	[]	[]	-7	hSpCas9	negative selection	2948297
179570133	179570156	3	+	27260157	SF268	viability	GATGGCGATAAAGGCAAACAAGG	ACTL6A	ENSG00000136518	-1.22199834065418	[]	[]	-7	hSpCas9	negative selection	2948675
179570092	179570115	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	0.21075220186933158	[2,2]	[3,2]	4	hSpCas9	positive selection	2968702
179570180	179570203	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-0.7190816769782593	[2,2]	[1,0]	-8	hSpCas9	positive selection	2968703
179573446	179573469	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	0.5523891225956923	[3,3]	[4,5]	9	hSpCas9	positive selection	2968704
179570221	179570244	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCACCTCTAAAAAATGGGATGGG	ACTL6A	ENSG00000136518	-0.08556622053077154	[2,3]	[3,0]	-1	hSpCas9	positive selection	2968705
179570092	179570115	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.003573667355153	[2,2]	[0,0]	-9	hSpCas9	positive selection	3036560
179570180	179570203	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-0.2827890773504238	[2,2]	[2,0]	-4	hSpCas9	positive selection	3036561
179573446	179573469	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-0.5608101664319615	[3,3]	[3,0]	-7	hSpCas9	positive selection	3036562
179570221	179570244	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCACCTCTAAAAAATGGGATGGG	ACTL6A	ENSG00000136518	0.1447937172932304	[2,2]	[2,1]	2	hSpCas9	positive selection	3036563
179576272	179576295		+	24336571	A375	resistance to PLX after 7 days	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-0.13596701393310062	[4,5]	[4,3]	-4	hSpCas9	positive selection	3159782
179576270	179576293		-	24336571	A375	resistance to PLX after 7 days	ATCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-0.012390700418461575	[5,6]	[6,5]	0	hSpCas9	positive selection	3159787
179576818	179576841		+	24336571	A375	resistance to PLX after 7 days	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	0.3328277745410048	[7,7]	[9,10]	8	hSpCas9	positive selection	3159792
179576875	179576898		-	24336571	A375	resistance to PLX after 7 days	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.02601237363872281	[11,12]	[13,10]	0	hSpCas9	positive selection	3159803
179576272	179576295		+	24336571	A375	resistance to PLX after 14 days	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	0.7542454718178909	[3,2]	[2,2]	6	hSpCas9	positive selection	3217575
179576270	179576293		-	24336571	A375	resistance to PLX after 14 days	ATCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	0.593221161913866	[3,6]	[2,3]	5	hSpCas9	positive selection	3217580
179576818	179576841		+	24336571	A375	resistance to PLX after 14 days	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	0.09286007596361909	[9,9]	[3,4]	1	hSpCas9	positive selection	3217585
179576875	179576898		-	24336571	A375	resistance to PLX after 14 days	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.12903126181589958	[8,8]	[3,2]	-1	hSpCas9	positive selection	3217596
179576272	179576295		+	24336571	A375	viability after 7 days	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-1.636719295205437	[17]	[4,5]	-9	hSpCas9	negative selection	3275368
179576270	179576293		-	24336571	A375	viability after 7 days	ATCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-1.793684573099164	[25]	[5,6]	-9	hSpCas9	negative selection	3275373
179576818	179576841		+	24336571	A375	viability after 7 days	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.147850549192718	[19]	[7,7]	-9	hSpCas9	negative selection	3275378
179576875	179576898		-	24336571	A375	viability after 7 days	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.3595502425516597	[34]	[11,12]	-9	hSpCas9	negative selection	3275389
179576272	179576295		+	24336571	A375	viability after 14 days	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-2.0773357221520605	[17]	[3,2]	-9	hSpCas9	negative selection	3333161
179576270	179576293		-	24336571	A375	viability after 14 days	ATCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-2.109296853071383	[25]	[3,6]	-9	hSpCas9	negative selection	3333166
179576818	179576841		+	24336571	A375	viability after 14 days	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.8712124290964749	[19]	[9,9]	-8	hSpCas9	negative selection	3333171
179576875	179576898		-	24336571	A375	viability after 14 days	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.8144424133109496	[34]	[8,8]	-9	hSpCas9	negative selection	3333182
179576286	179576309	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	1.8317194704568043	[39,45]	[0,0]	7	hSpCas9	positive selection	3335404
179576875	179576898	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	2.1499410183060723	[90,115]	[0,4]	7	hSpCas9	positive selection	3335405
179576229	179576252	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	-1.005213926762178	[642,584]	[0,2]	-6	hSpCas9	positive selection	3335406
179580648	179580671	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.49756129071763344	[215,215]	[0,0]	-3	hSpCas9	positive selection	3354654
179576818	179576841	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	0.6574133692587072	[96,96]	[0,0]	3	hSpCas9	positive selection	3354655
179580630	179580653	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-1.894958630860747	[568,568]	[0,0]	-9	hSpCas9	positive selection	3354656
179570091	179570114	3	+	26780180	HT29	viability (Avana library 4 designs)	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	2.15400977872755	[]	[]	7	hSpCas9	negative selection	3404650
179570179	179570202	3	+	26780180	HT29	viability (Avana library 4 designs)	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	3.87248118931444	[]	[]	9	hSpCas9	negative selection	3404651
179573446	179573469	3	-	26780180	HT29	viability (Avana library 4 designs)	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	6.40928467293249	[]	[]	9	hSpCas9	negative selection	3404652
179570220	179570243	3	+	26780180	HT29	viability (Avana library 4 designs)	TCACCTCTAAAAAATGGGATGGG	ACTL6A	ENSG00000136518	5.22174125857548	[]	[]	9	hSpCas9	negative selection	3404653
179570179	179570202	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-6.97219613691614	[]	[]	-6	hSpCas9	negative selection	3476291
179570091	179570114	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-6.94941209068754	[]	[]	-6	hSpCas9	negative selection	3476292
179573446	179573469	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-12.2465096247941	[]	[]	-8	hSpCas9	negative selection	3476293
179570220	179570243	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCACCTCTAAAAAATGGGATGGG	ACTL6A	ENSG00000136518	-21.0499843567455	[]	[]	-9	hSpCas9	negative selection	3476294
179573442	179573465	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCATCCTGTTCTCATGTCAGAGG	ACTL6A	ENSG00000136518	-12.4338667563143	[]	[]	-8	hSpCas9	negative selection	3476295
179570136	179570159	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-10.412917737533	[]	[]	-8	hSpCas9	negative selection	3476296
179570179	179570202	3	+	26780180	A375	viability (Avana lentiGuide)	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	24.0791130780415	[]	[]	9	hSpCas9	negative selection	3584950
179570091	179570114	3	+	26780180	A375	viability (Avana lentiGuide)	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	5.73075627326347	[]	[]	5	hSpCas9	negative selection	3584951
179573446	179573469	3	-	26780180	A375	viability (Avana lentiGuide)	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	17.0240968108304	[]	[]	8	hSpCas9	negative selection	3584952
179570220	179570243	3	+	26780180	A375	viability (Avana lentiGuide)	TCACCTCTAAAAAATGGGATGGG	ACTL6A	ENSG00000136518	13.9956007302152	[]	[]	7	hSpCas9	negative selection	3584953
179573442	179573465	3	+	26780180	A375	viability (Avana lentiGuide)	CCATCCTGTTCTCATGTCAGAGG	ACTL6A	ENSG00000136518	33.4376339239767	[]	[]	9	hSpCas9	negative selection	3584954
179570136	179570159	3	+	26780180	A375	viability (Avana lentiGuide)	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	6.75829869538812	[]	[]	5	hSpCas9	negative selection	3584955
179570179	179570202	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-0.7365056864915089	[5]	[3,2]	-8	hSpCas9	positive selection	3693609
179570091	179570114	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-0.41861449276617047	[6]	[4,4]	-6	hSpCas9	positive selection	3693610
179573446	179573469	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-0.8314402059690374	[5]	[2,2]	-8	hSpCas9	positive selection	3693611
179570220	179570243	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCACCTCTAAAAAATGGGATGGG	ACTL6A	ENSG00000136518	-1.9229226467108311	[6]	[0,0]	-9	hSpCas9	positive selection	3693612
179573442	179573465	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATCCTGTTCTCATGTCAGAGG	ACTL6A	ENSG00000136518	-0.6729456611409179	[5]	[3,3]	-7	hSpCas9	positive selection	3693613
179570136	179570159	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.9227611375347223	[4]	[2,1]	-8	hSpCas9	positive selection	3693614
179570179	179570202	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAATGCTCTGCGTGTTCCGAGG	ACTL6A	ENSG00000136518	-0.9442197007072518	[5]	[2,1]	-8	hSpCas9	positive selection	3802216
179570091	179570114	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.2957314373502469	[4]	[1,0]	-9	hSpCas9	positive selection	3802217
179573446	179573469	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-0.5763234273182004	[7]	[3,3]	-6	hSpCas9	positive selection	3802218
179570220	179570243	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCACCTCTAAAAAATGGGATGGG	ACTL6A	ENSG00000136518	-1.038126558988578	[5]	[2,1]	-8	hSpCas9	positive selection	3802219
179573442	179573465	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATCCTGTTCTCATGTCAGAGG	ACTL6A	ENSG00000136518	-1.6049904485388278	[6]	[1,0]	-9	hSpCas9	positive selection	3802220
179570136	179570159	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.26708607642841603	[6]	[4,3]	-4	hSpCas9	positive selection	3802221
179580648	179580671	3	-	26780180	A375	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	2.04546065153526	[]	[]	9	hSpCas9	negative selection	3910823
179576286	179576309	3	-	26780180	A375	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	1.73217012496751	[]	[]	9	hSpCas9	negative selection	3910824
179576229	179576252	3	+	26780180	A375	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	-0.265153176309522	[]	[]	-7	hSpCas9	negative selection	3910825
179576818	179576841	3	+	26780180	A375	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	1.82028622765388	[]	[]	9	hSpCas9	negative selection	3910826
179576875	179576898	3	-	26780180	A375	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	1.20063042016976	[]	[]	6	hSpCas9	negative selection	3910827
179580630	179580653	3	+	26780180	A375	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	2.0335905138811	[]	[]	9	hSpCas9	negative selection	3910828
179580648	179580671	3	-	26780180	HT29	viability (GeCKOv2 library)	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	2.14004264204079	[]	[]	9	hSpCas9	negative selection	4018789
179576286	179576309	3	-	26780180	HT29	viability (GeCKOv2 library)	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	2.527965769072	[]	[]	9	hSpCas9	negative selection	4018790
179576229	179576252	3	+	26780180	HT29	viability (GeCKOv2 library)	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	-0.408171610195777	[]	[]	-8	hSpCas9	negative selection	4018791
179576818	179576841	3	+	26780180	HT29	viability (GeCKOv2 library)	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	1.66359503424196	[]	[]	8	hSpCas9	negative selection	4018792
179576875	179576898	3	-	26780180	HT29	viability (GeCKOv2 library)	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	1.8494020166217	[]	[]	8	hSpCas9	negative selection	4018793
179580630	179580653	3	+	26780180	HT29	viability (GeCKOv2 library)	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	1.66436814955829	[]	[]	8	hSpCas9	negative selection	4018794
179576272	179576295	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-0.44790154678793537	[2]	[0,1]	-8	hSpCas9	positive selection	4187736
179576270	179576293	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-0.15556255302538127	[3]	[2,1]	-4	hSpCas9	positive selection	4187747
179576818	179576841	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.2699899813712927	[3]	[1,2]	-6	hSpCas9	positive selection	4187758
179576875	179576898	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.17757966701408678	[4]	[3,1]	-4	hSpCas9	positive selection	4187769
179576272	179576295	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-0.25146101388598446	[3]	[2,0,1,0]	-4	hSpCas9	positive selection	4251758
179576270	179576293	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-0.6982485867038896	[5]	[0,1,0,0]	-8	hSpCas9	positive selection	4251769
179576818	179576841	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	0.7398316769443841	[4]	[0,3,1,3]	5	hSpCas9	positive selection	4251780
179576875	179576898	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	1.1124886602918524	[4]	[3,3,4,5]	8	hSpCas9	positive selection	4251791
179576286	179576309	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-0.7295871246925274	[2]	[0,0]	-9	hSpCas9	positive selection	4254323
179576875	179576898	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.25652803788796474	[3]	[2,1]	-5	hSpCas9	positive selection	4254324
179576229	179576252	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.40058148242688657	[4]	[5,4]	7	hSpCas9	positive selection	4254325
179580648	179580671	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.4177317599787306	[3]	[2,1]	-7	hSpCas9	positive selection	4318606
179576818	179576841	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.08975273412518461	[3]	[2,1]	-2	hSpCas9	positive selection	4318607
179580630	179580653	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.097266691436934	[5]	[4,2]	-2	hSpCas9	positive selection	4318608
179570190	179570212	3	+	27760321	OCIAML3	viability	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.8136645140832532	[289,218]	[64,173]	-6	hSpCas9	negative selection	4375876
179576237	179576259	3	+	27760321	OCIAML3	viability	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-1.400257595569047	[716,576]	[151,240]	-8	hSpCas9	negative selection	4375877
179576270	179576292	3	-	27760321	OCIAML3	viability	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-2.405048577212141	[423,420]	[39,91]	-9	hSpCas9	negative selection	4375878
179576291	179576313	3	+	27760321	OCIAML3	viability	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.6892727182494378	[172,168]	[41,40]	-8	hSpCas9	negative selection	4375879
179576634	179576656	3	-	27760321	OCIAML3	viability	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-0.9432800472206537	[114,100]	[22,70]	-7	hSpCas9	negative selection	4375880
179570190	179570212	3	+	27760321	OCIAML2	viability	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-1.8305875186619873	[289,218]	[59,53]	-9	hSpCas9	negative selection	4459339
179576237	179576259	3	+	27760321	OCIAML2	viability	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-1.346556829633927	[716,576]	[211,194]	-8	hSpCas9	negative selection	4459340
179576270	179576292	3	-	27760321	OCIAML2	viability	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-2.2537519899084892	[423,420]	[26,130]	-9	hSpCas9	negative selection	4459341
179576291	179576313	3	+	27760321	OCIAML2	viability	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-3.1421584689021396	[172,168]	[16,13]	-9	hSpCas9	negative selection	4459342
179576634	179576656	3	-	27760321	OCIAML2	viability	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-2.2652335953125675	[114,100]	[18,16]	-9	hSpCas9	negative selection	4459343
179570190	179570212	3	+	27760321	MV411	viability	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-2.1327787736820936	[289,218]	[15,70]	-8	hSpCas9	negative selection	4542802
179576237	179576259	3	+	27760321	MV411	viability	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-0.9575516860086308	[716,576]	[3,540]	-6	hSpCas9	negative selection	4542803
179576270	179576292	3	-	27760321	MV411	viability	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-2.477424149875361	[423,420]	[66,24]	-9	hSpCas9	negative selection	4542804
179576291	179576313	3	+	27760321	MV411	viability	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	0.19605201847401443	[172,168]	[91,185]	1	hSpCas9	negative selection	4542805
179576634	179576656	3	-	27760321	MV411	viability	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	1.7838034454615452	[114,100]	[369,56]	9	hSpCas9	negative selection	4542806
179570190	179570212	3	+	27760321	HL60	viability	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-1.4754967097488325	[289,218]	[45,103]	-8	hSpCas9	negative selection	4626265
179576237	179576259	3	+	27760321	HL60	viability	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-1.242919413653822	[716,576]	[223,219]	-8	hSpCas9	negative selection	4626266
179576270	179576292	3	-	27760321	HL60	viability	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-1.04486225046019	[423,420]	[143,192]	-7	hSpCas9	negative selection	4626267
179576291	179576313	3	+	27760321	HL60	viability	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-0.44183790194088046	[172,168]	[88,117]	-5	hSpCas9	negative selection	4626268
179576634	179576656	3	-	27760321	HL60	viability	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-0.406081665433109	[114,100]	[47,85]	-4	hSpCas9	negative selection	4626269
179570190	179570212	3	+	27760321	HT1080	viability	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.2403485932132482	[218,170]	[123,1]	-1	hSpCas9	negative selection	4709728
179576237	179576259	3	+	27760321	HT1080	viability	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-4.647720023368621	[576,449]	[0,15]	-8	hSpCas9	negative selection	4709729
179576270	179576292	3	-	27760321	HT1080	viability	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-3.118533118477475	[420,328]	[31,0]	-7	hSpCas9	negative selection	4709730
179576291	179576313	3	+	27760321	HT1080	viability	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-3.261814175199407	[168,131]	[0,11]	-7	hSpCas9	negative selection	4709731
179576634	179576656	3	-	27760321	HT1080	viability	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-5.16423202337599	[100,78]	[0,0]	-8	hSpCas9	negative selection	4709732
179570190	179570212	3	+	27760321	HT29	viability after 7 days	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.4656407960379244	[218,170]	[239,170,142]	-6	hSpCas9	negative selection	4793191
179576237	179576259	3	+	27760321	HT29	viability after 7 days	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-0.2585995914808803	[576,449]	[655,442,569]	-4	hSpCas9	negative selection	4793192
179576270	179576292	3	-	27760321	HT29	viability after 7 days	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-1.34311090601315	[420,328]	[129,134,292]	-9	hSpCas9	negative selection	4793193
179576291	179576313	3	+	27760321	HT29	viability after 7 days	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-0.8573084918013383	[168,131]	[131,88,102]	-8	hSpCas9	negative selection	4793194
179576634	179576656	3	-	27760321	HT29	viability after 7 days	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-0.9378834019025295	[100,78]	[66,51,62]	-8	hSpCas9	negative selection	4793195
179570190	179570212	3	+	27760321	HT29	viability after 25 days	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-3.7328214438437843	[218,170]	[9,3,38]	-9	hSpCas9	negative selection	4876654
179576237	179576259	3	+	27760321	HT29	viability after 25 days	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-2.979100508109898	[576,449]	[34,69,125]	-8	hSpCas9	negative selection	4876655
179576270	179576292	3	-	27760321	HT29	viability after 25 days	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-4.371435375216435	[420,328]	[15,28,16]	-9	hSpCas9	negative selection	4876656
179576291	179576313	3	+	27760321	HT29	viability after 25 days	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-4.988685656338395	[168,131]	[1,12,0]	-9	hSpCas9	negative selection	4876657
179576634	179576656	3	-	27760321	HT29	viability after 25 days	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-6.683914288222514	[100,78]	[0,0,0]	-9	hSpCas9	negative selection	4876658
179570190	179570212	3	+	27760321	HT29	viability after 22 days	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-3.8182134147729085	[218,170]	[14,13,18]	-9	hSpCas9	negative selection	4960117
179576237	179576259	3	+	27760321	HT29	viability after 22 days	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-3.714370042142491	[576,449]	[35,45,53]	-9	hSpCas9	negative selection	4960118
179576270	179576292	3	-	27760321	HT29	viability after 22 days	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-3.181021981468748	[420,328]	[69,4,67]	-8	hSpCas9	negative selection	4960119
179576291	179576313	3	+	27760321	HT29	viability after 22 days	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-3.5438336245058037	[168,131]	[0,42,0]	-9	hSpCas9	negative selection	4960120
179576634	179576656	3	-	27760321	HT29	viability after 22 days	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-6.7012329200817735	[100,78]	[0,0,0]	-9	hSpCas9	negative selection	4960121
179570190	179570212	3	+	27760321	HT29	viability after 19 days	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-2.371797051409225	[218,170]	[54,72,3]	-8	hSpCas9	negative selection	5043580
179576237	179576259	3	+	27760321	HT29	viability after 19 days	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-4.423805590559206	[576,449]	[0,15,60]	-9	hSpCas9	negative selection	5043581
179576270	179576292	3	-	27760321	HT29	viability after 19 days	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-6.1949456897191455	[420,328]	[8,5,2]	-9	hSpCas9	negative selection	5043582
179576291	179576313	3	+	27760321	HT29	viability after 19 days	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-7.427032267725552	[168,131]	[0,0,0]	-9	hSpCas9	negative selection	5043583
179576634	179576656	3	-	27760321	HT29	viability after 19 days	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-4.437756249926235	[100,78]	[0,11,0]	-9	hSpCas9	negative selection	5043584
179570190	179570212	3	+	27760321	HT29	viability after 16 days	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-2.833865572489507	[218,170]	[13,0,75]	-9	hSpCas9	negative selection	5127043
179576237	179576259	3	+	27760321	HT29	viability after 16 days	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-3.1643420722288402	[576,449]	[50,101,36]	-9	hSpCas9	negative selection	5127044
179576270	179576292	3	-	27760321	HT29	viability after 16 days	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-4.589441341017988	[420,328]	[10,4,35]	-9	hSpCas9	negative selection	5127045
179576291	179576313	3	+	27760321	HT29	viability after 16 days	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-3.9057387342895513	[168,131]	[32,1,0]	-9	hSpCas9	negative selection	5127046
179576634	179576656	3	-	27760321	HT29	viability after 16 days	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-5.888372945027788	[100,78]	[0,2,0]	-9	hSpCas9	negative selection	5127047
179570190	179570212	3	+	27760321	HT29	viability after 13 days	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-2.673733275147673	[218,170]	[38,42,24]	-9	hSpCas9	negative selection	5210506
179576237	179576259	3	+	27760321	HT29	viability after 13 days	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-3.113060663718934	[576,449]	[78,49,76]	-9	hSpCas9	negative selection	5210507
179576270	179576292	3	-	27760321	HT29	viability after 13 days	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-4.323299354846771	[420,328]	[16,39,8]	-9	hSpCas9	negative selection	5210508
179576291	179576313	3	+	27760321	HT29	viability after 13 days	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-5.732030614722504	[168,131]	[1,6,0]	-9	hSpCas9	negative selection	5210509
179576634	179576656	3	-	27760321	HT29	viability after 13 days	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-5.131813050515975	[100,78]	[0,5,1]	-9	hSpCas9	negative selection	5210510
179570190	179570212	3	+	27760321	HT29	viability after 10 days	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	-0.6310934935381572	[218,170]	[188,150,131]	-6	hSpCas9	negative selection	5293969
179576237	179576259	3	+	27760321	HT29	viability after 10 days	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-2.257462137554417	[576,449]	[81,152,166]	-9	hSpCas9	negative selection	5293970
179576270	179576292	3	-	27760321	HT29	viability after 10 days	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-3.3585944559335643	[420,328]	[40,88,8]	-9	hSpCas9	negative selection	5293971
179576291	179576313	3	+	27760321	HT29	viability after 10 days	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-2.4849737153605718	[168,131]	[43,34,21]	-9	hSpCas9	negative selection	5293972
179576634	179576656	3	-	27760321	HT29	viability after 10 days	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-1.843296358462162	[100,78]	[42,26,23]	-9	hSpCas9	negative selection	5293973
179570190	179570212	3	+	27760321	MOLM13	viability	CGTGTTCCGAGGGAGAATATGG	ACTL6A	ENSG00000136518	0.04652338552231483	[289,218]	[71,210]	0	hSpCas9	negative selection	5377432
179576237	179576259	3	+	27760321	MOLM13	viability	CTGGGCTGATTTTGGACAGTGG	ACTL6A	ENSG00000136518	-0.9192036871163005	[716,576]	[158,219]	-5	hSpCas9	negative selection	5377433
179576270	179576292	3	-	27760321	MOLM13	viability	TCGTGGACTGGAATTGCAGTGG	ACTL6A	ENSG00000136518	-2.0256799863836394	[423,420]	[1,106]	-8	hSpCas9	negative selection	5377434
179576291	179576313	3	+	27760321	MOLM13	viability	ATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-3.0623630100668926	[172,168]	[23,0]	-9	hSpCas9	negative selection	5377435
179576634	179576656	3	-	27760321	MOLM13	viability	TAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-5.926211174860948	[114,100]	[0,0]	-9	hSpCas9	negative selection	5377436
179563298	179563321	3	+	27661255	K562	viability	GCTCCTCGGGCTCCCTGAAGTGG	ACTL6A	ENSG00000136518	-0.5659566205954341	[195,199]	[95,115]	-8	dCas9-KRAB	negative selection	5460734
179563373	179563396	3	+	27661255	K562	viability	GGTGCGCGCTCGGTTCTCTAGGG	ACTL6A	ENSG00000136518	-0.21312819237578345	[1086,1052]	[801,682]	-6	dCas9-KRAB	negative selection	5460735
179563196	179563219	3	-	27661255	K562	viability	GAGACCGGAAGGGAACGCCGGGG	ACTL6A	ENSG00000136518	-0.29677782818402565	[847,957]	[647,532]	-7	dCas9-KRAB	negative selection	5460736
179576286	179576309	3	-	27260156	BXPC3	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.21269364566548	[265]	[94,119,133,134]	-9	hSpCas9	negative selection	5526783
179576875	179576898	3	-	27260156	BXPC3	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.3423417565352327	[712]	[313,209,309,349]	-9	hSpCas9	negative selection	5526784
179576229	179576252	3	+	27260156	BXPC3	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.4322881776201224	[1483]	[1968,2043,1957,2446]	8	hSpCas9	negative selection	5526785
179580648	179580671	3	-	27260156	BXPC3	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.7604989712858635	[828]	[373,469,593,639]	-9	hSpCas9	negative selection	5591066
179576818	179576841	3	+	27260156	BXPC3	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.814530185669315	[594]	[320,261,411,437]	-9	hSpCas9	negative selection	5591067
179580630	179580653	3	+	27260156	BXPC3	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.3876733523230398	[2127]	[1643,1667,1822,1660]	-7	hSpCas9	negative selection	5591068
179576286	179576309	3	-	27260156	A673	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-0.627248525945464	[265]	[185,227,228,178]	-9	hSpCas9	negative selection	5648034
179576875	179576898	3	-	27260156	A673	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.45186096470371356	[712]	[623,574,619,687]	-8	hSpCas9	negative selection	5648035
179576229	179576252	3	+	27260156	A673	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.19192718889259508	[1483]	[2358,1756,1859,2217]	4	hSpCas9	negative selection	5648036
179580648	179580671	3	-	27260156	A673	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.4419645128708829	[828]	[980,648,621,707]	-8	hSpCas9	negative selection	5712317
179576818	179576841	3	+	27260156	A673	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.3435359632165753	[594]	[637,505,543,573]	-7	hSpCas9	negative selection	5712318
179580630	179580653	3	+	27260156	A673	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.30754437858425954	[2127]	[2062,2115,1983,2091]	-6	hSpCas9	negative selection	5712319
179576286	179576309	3	-	27260156	A375	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.8523155298326324	[265]	[13,57,32,65]	-9	hSpCas9	negative selection	5769285
179576875	179576898	3	-	27260156	A375	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.264145586409718	[712]	[422,362,510,118]	-8	hSpCas9	negative selection	5769286
179576229	179576252	3	+	27260156	A375	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.3289585827752437	[1483]	[2404,2540,2076,1777]	5	hSpCas9	negative selection	5769287
179580648	179580671	3	-	27260156	A375	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.8192828447403064	[828]	[807,546,498,362]	-8	hSpCas9	negative selection	5833568
179576818	179576841	3	+	27260156	A375	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.0384062394176188	[594]	[389,485,241,263]	-8	hSpCas9	negative selection	5833569
179580630	179580653	3	+	27260156	A375	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.6308030582076309	[2127]	[1392,1786,1734,1531]	-7	hSpCas9	negative selection	5833570
179576286	179576309	3	-	27260156	COLO741	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.694832527469159	[265]	[99,132,82]	-9	hSpCas9	negative selection	5890536
179576875	179576898	3	-	27260156	COLO741	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.259925911566017	[712]	[361,342,429]	-9	hSpCas9	negative selection	5890537
179576229	179576252	3	+	27260156	COLO741	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.3131135810913601	[1483]	[2659,2335,2109]	6	hSpCas9	negative selection	5890538
179580648	179580671	3	-	27260156	COLO741	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.43584725833783816	[828]	[749,788,803]	-7	hSpCas9	negative selection	5954819
179576818	179576841	3	+	27260156	COLO741	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.5225630857062394	[594]	[468,617,496]	-8	hSpCas9	negative selection	5954820
179580630	179580653	3	+	27260156	COLO741	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.3427050913006868	[2127]	[1972,2069,2353]	-6	hSpCas9	negative selection	5954821
179576286	179576309	3	-	27260156	CAL120	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.6219424315239643	[265]	[76,133,106]	-9	hSpCas9	negative selection	6011787
179576875	179576898	3	-	27260156	CAL120	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.588362491013597	[712]	[375,269,251]	-9	hSpCas9	negative selection	6011788
179576229	179576252	3	+	27260156	CAL120	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.594682933917634	[1483]	[3636,1917,2934]	8	hSpCas9	negative selection	6011789
179580648	179580671	3	-	27260156	CAL120	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-1.0128605875405325	[828]	[658,458,438]	-8	hSpCas9	negative selection	6076070
179576818	179576841	3	+	27260156	CAL120	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.8556431066222723	[594]	[283,375,545]	-8	hSpCas9	negative selection	6076071
179580630	179580653	3	+	27260156	CAL120	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.2598392395744258	[2127]	[2513,2322,1848]	-4	hSpCas9	negative selection	6076072
179576286	179576309	3	-	27260156	CADOES1	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-0.5853461570686623	[265]	[131,113,235,177]	-8	hSpCas9	negative selection	6133038
179576875	179576898	3	-	27260156	CADOES1	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.3381190634452717	[712]	[504,571,483,537]	-5	hSpCas9	negative selection	6133039
179576229	179576252	3	+	27260156	CADOES1	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.7626871337239605	[1483]	[2232,2429,1963,2755]	9	hSpCas9	negative selection	6133040
179580648	179580671	3	-	27260156	CADOES1	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.03416765360650342	[828]	[551,909,815,733]	0	hSpCas9	negative selection	6197321
179576818	179576841	3	+	27260156	CADOES1	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.3224101549010789	[594]	[627,354,384,399]	-5	hSpCas9	negative selection	6197322
179580630	179580653	3	+	27260156	CADOES1	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.034864509701335145	[2127]	[1910,1946,1955,1912]	0	hSpCas9	negative selection	6197323
179576286	179576309	3	-	27260156	EWS502	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.9602810212810429	[265]	[58,78,60,92]	-9	hSpCas9	negative selection	6254289
179576875	179576898	3	-	27260156	EWS502	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.8374707064997768	[712]	[238,184,207,209]	-9	hSpCas9	negative selection	6254290
179576229	179576252	3	+	27260156	EWS502	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.6028360234378276	[1483]	[2246,2445,2619,2232]	9	hSpCas9	negative selection	6254291
179580648	179580671	3	-	27260156	EWS502	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-1.258525745059797	[828]	[384,235,456,394]	-9	hSpCas9	negative selection	6318572
179576818	179576841	3	+	27260156	EWS502	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.945108809818934	[594]	[299,386,204,421]	-8	hSpCas9	negative selection	6318573
179580630	179580653	3	+	27260156	EWS502	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.36276572206248936	[2127]	[1946,1481,1838,1722]	-6	hSpCas9	negative selection	6318574
179576286	179576309	3	-	27260156	EW8	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.741209396865715	[265]	[90,88,45,37]	-9	hSpCas9	negative selection	6375540
179576875	179576898	3	-	27260156	EW8	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.1861921377204907	[712]	[243,315,165,302]	-9	hSpCas9	negative selection	6375541
179576229	179576252	3	+	27260156	EW8	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.5348167373648174	[1483]	[1805,1623,1745,1793]	8	hSpCas9	negative selection	6375542
179580648	179580671	3	-	27260156	EW8	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.2774258117562892	[828]	[339,430,898,462]	-5	hSpCas9	negative selection	6439823
179576818	179576841	3	+	27260156	EW8	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.9240878758120921	[594]	[389,195,227,220]	-9	hSpCas9	negative selection	6439824
179580630	179580653	3	+	27260156	EW8	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.3703562324297438	[2127]	[1490,1170,1285,1408]	-6	hSpCas9	negative selection	6439825
179576286	179576309	3	-	27260156	CORL105	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.3141882836249388	[265]	[83,120,72,212]	-9	hSpCas9	negative selection	6496791
179576875	179576898	3	-	27260156	CORL105	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.711824556809836	[712]	[396,490,457,679]	-8	hSpCas9	negative selection	6496792
179576229	179576252	3	+	27260156	CORL105	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	-0.05897558539618153	[1483]	[1552,1523,2029,1618]	-1	hSpCas9	negative selection	6496793
179580648	179580671	3	-	27260156	CORL105	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.5615433388831734	[828]	[587,567,889,619]	-7	hSpCas9	negative selection	6561074
179576818	179576841	3	+	27260156	CORL105	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.25736941149075	[594]	[268,225,412,276]	-9	hSpCas9	negative selection	6561075
179580630	179580653	3	+	27260156	CORL105	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.5424884102167824	[2127]	[1589,1663,2002,1626]	-7	hSpCas9	negative selection	6561076
179576286	179576309	3	-	27260156	HS294T	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.4495335647601681	[265]	[62,15,35,32]	-9	hSpCas9	negative selection	6618042
179576875	179576898	3	-	27260156	HS294T	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.2318892225149396	[712]	[96,122,127,123]	-9	hSpCas9	negative selection	6618043
179576229	179576252	3	+	27260156	HS294T	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.5604130461603347	[1483]	[729,945,730,1009]	7	hSpCas9	negative selection	6618044
179580648	179580671	3	-	27260156	HS294T	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	0.13009840987126275	[828]	[228,138,277,859]	1	hSpCas9	negative selection	6682325
179576818	179576841	3	+	27260156	HS294T	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.8694251297748614	[594]	[97,106,128,181]	-8	hSpCas9	negative selection	6682326
179580630	179580653	3	+	27260156	HS294T	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.42236448385087355	[2127]	[458,582,583,889]	-5	hSpCas9	negative selection	6682327
179576286	179576309	3	-	27260156	HCC44	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.415266608031431	[265]	[83,48,29,60]	-9	hSpCas9	negative selection	6739293
179576875	179576898	3	-	27260156	HCC44	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.3966466797106845	[712]	[315,332,235,321]	-9	hSpCas9	negative selection	6739294
179576229	179576252	3	+	27260156	HCC44	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.6112364323779356	[1483]	[2488,2386,3473,2075]	8	hSpCas9	negative selection	6739295
179580648	179580671	3	-	27260156	HCC44	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.9887615952043894	[828]	[302,431,743,444]	-8	hSpCas9	negative selection	6803576
179576818	179576841	3	+	27260156	HCC44	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.193019423004582	[594]	[224,342,281,308]	-9	hSpCas9	negative selection	6803577
179580630	179580653	3	+	27260156	HCC44	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.3350863769662962	[2127]	[1905,1536,2221,2052]	-5	hSpCas9	negative selection	6803578
179576286	179576309	3	-	27260156	G402	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.0722349543521048	[265]	[454,93,106,7]	-8	hSpCas9	negative selection	6860544
179576875	179576898	3	-	27260156	G402	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.2977518805518922	[712]	[204,694,317,201]	-9	hSpCas9	negative selection	6860545
179576229	179576252	3	+	27260156	G402	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.7078105210229038	[1483]	[2631,3977,3065,2192]	8	hSpCas9	negative selection	6860546
179580648	179580671	3	-	27260156	G402	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.4836546861199599	[828]	[264,806,1255,511]	-6	hSpCas9	negative selection	6924827
179576818	179576841	3	+	27260156	G402	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.0170558509921264	[594]	[269,237,509,393]	-8	hSpCas9	negative selection	6924828
179580630	179580653	3	+	27260156	G402	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.4116637075619507	[2127]	[2733,1923,1879,1400]	-5	hSpCas9	negative selection	6924829
179576286	179576309	3	-	27260156	L33	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-0.9826728087405098	[265]	[103,41,89,188]	-9	hSpCas9	negative selection	6981795
179576875	179576898	3	-	27260156	L33	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.9288631004046966	[712]	[310,138,249,450]	-9	hSpCas9	negative selection	6981796
179576229	179576252	3	+	27260156	L33	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.4046040760916547	[1483]	[1984,791,1139,2122]	8	hSpCas9	negative selection	6981797
179580648	179580671	3	-	27260156	L33	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	0.19852535076482236	[828]	[815,462,501,1061]	4	hSpCas9	negative selection	7046078
179576818	179576841	3	+	27260156	L33	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.09704639462992606	[594]	[724,183,329,521]	-2	hSpCas9	negative selection	7046079
179580630	179580653	3	+	27260156	L33	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.2702903199743323	[2127]	[1828,727,1174,1582]	-6	hSpCas9	negative selection	7046080
179576286	179576309	3	-	27260156	K562	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.0138055203450413	[265]	[48,47,83,51]	-9	hSpCas9	negative selection	7103046
179576875	179576898	3	-	27260156	K562	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.6544516859623948	[712]	[74,127,422,166]	-9	hSpCas9	negative selection	7103047
179576229	179576252	3	+	27260156	K562	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	1.0131450578301688	[1483]	[3674,2375,2007,2632]	9	hSpCas9	negative selection	7103048
179580648	179580671	3	-	27260156	K562	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.8031212687164947	[828]	[404,483,275,510]	-7	hSpCas9	negative selection	7167329
179576818	179576841	3	+	27260156	K562	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.1585498173542221	[594]	[340,200,259,158]	-8	hSpCas9	negative selection	7167330
179580630	179580653	3	+	27260156	K562	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.13670013933037106	[2127]	[2070,1821,1532,1497]	-2	hSpCas9	negative selection	7167331
179576286	179576309	3	-	27260156	HT29	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.2483150162959067	[265]	[64,29,138,37]	-9	hSpCas9	negative selection	7224297
179576875	179576898	3	-	27260156	HT29	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.0638432472571746	[712]	[479,262,512,393]	-9	hSpCas9	negative selection	7224298
179576229	179576252	3	+	27260156	HT29	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.45688431392392426	[1483]	[2792,2742,2293,2144]	8	hSpCas9	negative selection	7224299
179580648	179580671	3	-	27260156	HT29	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.8049696921610839	[828]	[642,539,751,392]	-8	hSpCas9	negative selection	7288580
179576818	179576841	3	+	27260156	HT29	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.7346301735271493	[594]	[318,487,370,539]	-8	hSpCas9	negative selection	7288581
179580630	179580653	3	+	27260156	HT29	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.32969248243784777	[2127]	[2107,2050,2106,1966]	-6	hSpCas9	negative selection	7288582
179576286	179576309	3	-	27260156	MHHES1	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.313678113280894	[265]	[182,23,97,161]	-9	hSpCas9	negative selection	7345548
179576875	179576898	3	-	27260156	MHHES1	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.7595178765572103	[712]	[473,590,487,369]	-8	hSpCas9	negative selection	7345549
179576229	179576252	3	+	27260156	MHHES1	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.35659079246677594	[1483]	[2846,2185,1814,1824]	6	hSpCas9	negative selection	7345550
179580648	179580671	3	-	27260156	MHHES1	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.6639840519306253	[828]	[806,667,423,498]	-8	hSpCas9	negative selection	7409831
179576818	179576841	3	+	27260156	MHHES1	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.42917279957880516	[594]	[326,586,596,464]	-7	hSpCas9	negative selection	7409832
179580630	179580653	3	+	27260156	MHHES1	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.4973415865127979	[2127]	[1793,1799,1787,1450]	-7	hSpCas9	negative selection	7409833
179576286	179576309	3	-	27260156	MEWO	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.7471800239524056	[265]	[56,85,75]	-9	hSpCas9	negative selection	7466799
179576875	179576898	3	-	27260156	MEWO	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.8844969916027883	[712]	[313,306,453]	-9	hSpCas9	negative selection	7466800
179576229	179576252	3	+	27260156	MEWO	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.38190534476152393	[1483]	[2027,1687,1753]	7	hSpCas9	negative selection	7466801
179580648	179580671	3	-	27260156	MEWO	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.5324969592544171	[828]	[629,466,529]	-8	hSpCas9	negative selection	7531082
179576818	179576841	3	+	27260156	MEWO	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.3064374701880878	[594]	[379,391,564]	-6	hSpCas9	negative selection	7531083
179580630	179580653	3	+	27260156	MEWO	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.26846478018294495	[2127]	[2031,1361,1638]	-5	hSpCas9	negative selection	7531084
179576286	179576309	3	-	27260156	LNCAPCLONEFGC	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.1748278203075082	[265]	[80,84,242,39]	-9	hSpCas9	negative selection	7588050
179576875	179576898	3	-	27260156	LNCAPCLONEFGC	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.9995882184346426	[712]	[227,319,410,347]	-8	hSpCas9	negative selection	7588051
179576229	179576252	3	+	27260156	LNCAPCLONEFGC	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.5460340245525339	[1483]	[1845,1921,2281,1851]	8	hSpCas9	negative selection	7588052
179580648	179580671	3	-	27260156	LNCAPCLONEFGC	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.563729585428823	[828]	[590,339,619,506]	-7	hSpCas9	negative selection	7652333
179576818	179576841	3	+	27260156	LNCAPCLONEFGC	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.1545254055066312	[594]	[262,141,278,295]	-9	hSpCas9	negative selection	7652334
179580630	179580653	3	+	27260156	LNCAPCLONEFGC	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.11680781002623997	[2127]	[1448,1735,2229,1770]	-2	hSpCas9	negative selection	7652335
179576286	179576309	3	-	27260156	PANC0327	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.0483461265024396	[265]	[164,20,42,12]	-9	hSpCas9	negative selection	7709301
179576875	179576898	3	-	27260156	PANC0327	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.4376386457860046	[712]	[360,182,133,273]	-9	hSpCas9	negative selection	7709302
179576229	179576252	3	+	27260156	PANC0327	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.6395039877357145	[1483]	[2641,1730,2210,1719]	8	hSpCas9	negative selection	7709303
179580648	179580671	3	-	27260156	PANC0327	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.8098471744853031	[828]	[631,144,421,533]	-8	hSpCas9	negative selection	7773584
179576818	179576841	3	+	27260156	PANC0327	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.9990734677724378	[594]	[152,230,360,307]	-8	hSpCas9	negative selection	7773585
179580630	179580653	3	+	27260156	PANC0327	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.21199653459098822	[2127]	[1929,1462,1724,1455]	-3	hSpCas9	negative selection	7773586
179576286	179576309	3	-	27260156	NCIH2009	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.5817626005526204	[265]	[110,50,33]	-9	hSpCas9	negative selection	7830552
179576875	179576898	3	-	27260156	NCIH2009	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.9955882091014328	[712]	[625,552,342]	-8	hSpCas9	negative selection	7830553
179576229	179576252	3	+	27260156	NCIH2009	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.39681633406027306	[1483]	[2930,2760,2531]	5	hSpCas9	negative selection	7830554
179580648	179580671	3	-	27260156	NCIH2009	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.6742092401501935	[828]	[602,946,597]	-7	hSpCas9	negative selection	7894835
179576818	179576841	3	+	27260156	NCIH2009	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.3494928391437218	[594]	[343,361,274]	-8	hSpCas9	negative selection	7894836
179580630	179580653	3	+	27260156	NCIH2009	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.678154479867221	[2127]	[2016,1614,1974]	-7	hSpCas9	negative selection	7894837
179576286	179576309	3	-	27260156	NCIH1373	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.4023193933428413	[265]	[89,74,3,15]	-9	hSpCas9	negative selection	7951803
179576875	179576898	3	-	27260156	NCIH1373	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.2610522585629285	[712]	[993,287,360,301]	-3	hSpCas9	negative selection	7951804
179576229	179576252	3	+	27260156	NCIH1373	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	1.1483772751300791	[1483]	[4299,3213,3061,1143]	9	hSpCas9	negative selection	7951805
179580648	179580671	3	-	27260156	NCIH1373	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.6544346992057944	[828]	[1092,400,489,122]	-6	hSpCas9	negative selection	8016086
179576818	179576841	3	+	27260156	NCIH1373	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.0918466872677255	[594]	[369,233,472,46]	-8	hSpCas9	negative selection	8016087
179580630	179580653	3	+	27260156	NCIH1373	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.3690017348904395	[2127]	[2288,1641,1586,515]	-4	hSpCas9	negative selection	8016088
179576286	179576309	3	-	27260156	PATU8902	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.685268445390351	[265]	[295,56,82,17]	-8	hSpCas9	negative selection	8073054
179576875	179576898	3	-	27260156	PATU8902	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.200919066722865	[712]	[567,477,341,347]	-8	hSpCas9	negative selection	8073055
179576229	179576252	3	+	27260156	PATU8902	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.9544180839861771	[1483]	[3430,3601,3587,5681]	8	hSpCas9	negative selection	8073056
179580648	179580671	3	-	27260156	PATU8902	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.7306308201289062	[828]	[627,1068,281,936]	-6	hSpCas9	negative selection	8137337
179576818	179576841	3	+	27260156	PATU8902	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.5704761179032474	[594]	[905,384,349,645]	-5	hSpCas9	negative selection	8137338
179580630	179580653	3	+	27260156	PATU8902	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.9430184769735992	[2127]	[1623,1609,1486,1432]	-7	hSpCas9	negative selection	8137339
179576286	179576309	3	-	27260156	PANC1	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.031716140802029	[265]	[46,26,13,117]	-9	hSpCas9	negative selection	8194305
179576875	179576898	3	-	27260156	PANC1	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.5901769084323927	[712]	[147,344,189,163]	-9	hSpCas9	negative selection	8194306
179576229	179576252	3	+	27260156	PANC1	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.5588975157435372	[1483]	[1706,2308,2007,1595]	8	hSpCas9	negative selection	8194307
179580648	179580671	3	-	27260156	PANC1	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.9681736307297225	[828]	[526,468,306,192]	-8	hSpCas9	negative selection	8258588
179576818	179576841	3	+	27260156	PANC1	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.32901877673279467	[594]	[830,396,231,184]	-5	hSpCas9	negative selection	8258589
179580630	179580653	3	+	27260156	PANC1	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.42747996219831563	[2127]	[1325,1935,1219,1093]	-6	hSpCas9	negative selection	8258590
179576286	179576309	3	-	27260156	PANC0813	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.714693661794743	[265]	[28,63,32,239]	-9	hSpCas9	negative selection	8315556
179576875	179576898	3	-	27260156	PANC0813	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.3176113814908663	[712]	[315,383,451,197]	-9	hSpCas9	negative selection	8315557
179576229	179576252	3	+	27260156	PANC0813	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.45919502923208455	[1483]	[2805,2546,1917,2348]	7	hSpCas9	negative selection	8315558
179580648	179580671	3	-	27260156	PANC0813	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-1.4295146188057126	[828]	[451,349,246,401]	-9	hSpCas9	negative selection	8379839
179576818	179576841	3	+	27260156	PANC0813	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.1419394487457046	[594]	[412,183,369,308]	-9	hSpCas9	negative selection	8379840
179580630	179580653	3	+	27260156	PANC0813	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.6753718358720509	[2127]	[1506,1587,1593,1563]	-7	hSpCas9	negative selection	8379841
179576286	179576309	3	-	27260156	RDES	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.3826098964187672	[265]	[125,93,76,175]	-9	hSpCas9	negative selection	8436807
179576875	179576898	3	-	27260156	RDES	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.2144591301730046	[712]	[225,381,426,403]	-9	hSpCas9	negative selection	8436808
179576229	179576252	3	+	27260156	RDES	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.4865798809580051	[1483]	[1851,2245,2870,2724]	7	hSpCas9	negative selection	8436809
179580648	179580671	3	-	27260156	RDES	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.8187062437071448	[828]	[374,627,611,564]	-8	hSpCas9	negative selection	8501090
179576818	179576841	3	+	27260156	RDES	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.9363987444059434	[594]	[264,291,409,503]	-9	hSpCas9	negative selection	8501091
179580630	179580653	3	+	27260156	RDES	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.5812130806819382	[2127]	[1307,1620,1697,1995]	-7	hSpCas9	negative selection	8501092
179576286	179576309	3	-	27260156	PC3	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-0.8315339643497249	[265]	[155,97,226,120]	-9	hSpCas9	negative selection	8558058
179576875	179576898	3	-	27260156	PC3	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.8819901434067164	[712]	[304,291,567,445]	-9	hSpCas9	negative selection	8558059
179576229	179576252	3	+	27260156	PC3	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.27771829527385283	[1483]	[1038,1744,3111,1968]	6	hSpCas9	negative selection	8558060
179580648	179580671	3	-	27260156	PC3	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.10701700451585483	[828]	[644,770,869,777]	-2	hSpCas9	negative selection	8622341
179576818	179576841	3	+	27260156	PC3	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.21276199603002816	[594]	[321,428,794,655]	-5	hSpCas9	negative selection	8622342
179580630	179580653	3	+	27260156	PC3	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.10918203835515561	[2127]	[1316,2027,2976,2015]	-2	hSpCas9	negative selection	8622343
179576286	179576309	3	-	27260156	PATU8988T	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.318728780792291	[265]	[55,42,56,48]	-9	hSpCas9	negative selection	8679309
179576875	179576898	3	-	27260156	PATU8988T	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.636792084699836	[712]	[395,540,519,312]	-7	hSpCas9	negative selection	8679310
179576229	179576252	3	+	27260156	PATU8988T	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.4778830105378713	[1483]	[2340,1887,2089,1627]	7	hSpCas9	negative selection	8679311
179580648	179580671	3	-	27260156	PATU8988T	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-1.025110977845645	[828]	[290,413,438,434]	-9	hSpCas9	negative selection	8743592
179576818	179576841	3	+	27260156	PATU8988T	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.5458546123043798	[594]	[210,532,346,506]	-7	hSpCas9	negative selection	8743593
179580630	179580653	3	+	27260156	PATU8988T	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.5052050087310314	[2127]	[1094,1554,1440,1736]	-7	hSpCas9	negative selection	8743594
179576286	179576309	3	-	27260156	T47D	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.5552694665945022	[265]	[101,109,110,97]	-9	hSpCas9	negative selection	8800560
179576875	179576898	3	-	27260156	T47D	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.9499254421960426	[712]	[395,506,313,499]	-9	hSpCas9	negative selection	8800561
179576229	179576252	3	+	27260156	T47D	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.42275685153749043	[1483]	[2486,2192,2247,2354]	8	hSpCas9	negative selection	8800562
179580648	179580671	3	-	27260156	T47D	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.27123886793910823	[828]	[820,774,763,844]	-5	hSpCas9	negative selection	8864843
179576818	179576841	3	+	27260156	T47D	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.6086780440360844	[594]	[462,470,370,514]	-8	hSpCas9	negative selection	8864844
179580630	179580653	3	+	27260156	T47D	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.06534163262771298	[2127]	[2612,2282,2349,2234]	-1	hSpCas9	negative selection	8864845
179576286	179576309	3	-	27260156	SU8686	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-2.7605141348368107	[265]	[75,47,6,13]	-9	hSpCas9	negative selection	8921811
179576875	179576898	3	-	27260156	SU8686	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.766504098863174	[712]	[201,258,183,171]	-9	hSpCas9	negative selection	8921812
179576229	179576252	3	+	27260156	SU8686	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.6696247740926031	[1483]	[2170,1795,2599,2977]	9	hSpCas9	negative selection	8921813
179580648	179580671	3	-	27260156	SU8686	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-1.3290613692281776	[828]	[268,419,266,345]	-9	hSpCas9	negative selection	8986094
179576818	179576841	3	+	27260156	SU8686	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-1.0695587338159116	[594]	[219,227,302,405]	-8	hSpCas9	negative selection	8986095
179580630	179580653	3	+	27260156	SU8686	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.790495486741372	[2127]	[1204,1200,1147,1336]	-8	hSpCas9	negative selection	8986096
179576286	179576309	3	-	27260156	SKES1	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.002791576229522	[265]	[154,95,144,130]	-9	hSpCas9	negative selection	9043062
179576875	179576898	3	-	27260156	SKES1	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-1.3185423693183609	[712]	[208,320,201,387]	-9	hSpCas9	negative selection	9043063
179576229	179576252	3	+	27260156	SKES1	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.28074259099751675	[1483]	[2362,1907,1695,1353]	6	hSpCas9	negative selection	9043064
179580648	179580671	3	-	27260156	SKES1	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.7296542924074509	[828]	[561,520,378,535]	-9	hSpCas9	negative selection	9107345
179576818	179576841	3	+	27260156	SKES1	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.43005085730310594	[594]	[537,383,342,493]	-7	hSpCas9	negative selection	9107346
179580630	179580653	3	+	27260156	SKES1	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.34683532671757855	[2127]	[1986,1808,1507,1444]	-6	hSpCas9	negative selection	9107347
179576286	179576309	3	-	27260156	TOV112D	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-1.712788720540718	[265]	[55,124,85,66]	-9	hSpCas9	negative selection	9164313
179576875	179576898	3	-	27260156	TOV112D	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.513339628664689	[712]	[386,740,382,537]	-7	hSpCas9	negative selection	9164314
179576229	179576252	3	+	27260156	TOV112D	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.3813840214801574	[1483]	[1782,2351,1779,1915]	7	hSpCas9	negative selection	9164315
179580648	179580671	3	-	27260156	TOV112D	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.43203567156166456	[828]	[649,759,576,514]	-7	hSpCas9	negative selection	9228596
179576818	179576841	3	+	27260156	TOV112D	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.33661486952192426	[594]	[377,488,429,582]	-6	hSpCas9	negative selection	9228597
179580630	179580653	3	+	27260156	TOV112D	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.2375752327722136	[2127]	[1744,1740,2161,1564]	-5	hSpCas9	negative selection	9228598
179576286	179576309	3	-	27260156	TC71	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-0.656644826779407	[265]	[239,117,203,157]	-9	hSpCas9	negative selection	9285564
179576875	179576898	3	-	27260156	TC71	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.5990873536366397	[712]	[627,424,418,548]	-9	hSpCas9	negative selection	9285565
179576229	179576252	3	+	27260156	TC71	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.35808378828452003	[1483]	[1885,1886,2009,2398]	8	hSpCas9	negative selection	9285566
179580648	179580671	3	-	27260156	TC71	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.28519230292905295	[828]	[703,710,712,793]	-6	hSpCas9	negative selection	9349847
179576818	179576841	3	+	27260156	TC71	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.43474348374620403	[594]	[496,476,489,418]	-8	hSpCas9	negative selection	9349848
179580630	179580653	3	+	27260156	TC71	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.27740943755175684	[2127]	[1956,1949,1731,1892]	-6	hSpCas9	negative selection	9349849
179576286	179576309	3	-	27260156	TC32	viability	GTTGAAGGACATAGCCATCGTGG	ACTL6A	ENSG00000136518	-0.6115527993288609	[265]	[108,97,257,232]	-8	hSpCas9	negative selection	9406815
179576875	179576898	3	-	27260156	TC32	viability	TGCCAAGACCTCGTAACCTGAGG	ACTL6A	ENSG00000136518	-0.8941951474960126	[712]	[411,222,402,439]	-9	hSpCas9	negative selection	9406816
179576229	179576252	3	+	27260156	TC32	viability	TCGTTCTACTGGGCTGATTTTGG	ACTL6A	ENSG00000136518	0.35318424931417924	[1483]	[1639,1549,2163,1834]	6	hSpCas9	negative selection	9406817
179580648	179580671	3	-	27260156	TC32	viability	GTACCGAAGCTTGAAAATCCTGG	ACTL6A	ENSG00000136518	-0.37410623980965796	[828]	[519,417,777,773]	-6	hSpCas9	negative selection	9471098
179576818	179576841	3	+	27260156	TC32	viability	TCTCAGGAAGCTGTTCGTGAAGG	ACTL6A	ENSG00000136518	-0.6473962757674429	[594]	[311,325,396,396]	-8	hSpCas9	negative selection	9471099
179580630	179580653	3	+	27260156	TC32	viability	TTACTCACAGTGTGTTATCCAGG	ACTL6A	ENSG00000136518	-0.16857442509788312	[2127]	[1829,1433,2042,1873]	-3	hSpCas9	negative selection	9471100
179569853	179569876	3	+	27869803	HPAFII	viability after 27 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-6.031083790956867	[293]	[3,0,NaN]	-9	hSpCas9	negative selection	9583610
179570136	179570159	3	+	27869803	HPAFII	viability after 27 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.7244962422039898	[281]	[92,86,NaN]	-5	hSpCas9	negative selection	9583611
179570180	179570203	3	+	27869803	HPAFII	viability after 27 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	0.07910654499250702	[54]	[47,15,NaN]	0	hSpCas9	negative selection	9583612
179576281	179576304	3	-	27869803	HPAFII	viability after 27 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.5850441034271872	[220]	[59,20,NaN]	-7	hSpCas9	negative selection	9583613
179576290	179576313	3	+	27869803	HPAFII	viability after 27 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-2.288397127397316	[135]	[30,0,NaN]	-8	hSpCas9	negative selection	9583614
179580961	179580984	3	+	27869803	HPAFII	viability after 27 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.213489684394424	[80]	[0,15,NaN]	-8	hSpCas9	negative selection	9583615
179569853	179569876	3	+	27869803	HPAFII	viability after 15 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-3.136911314587018	[293]	[75,10,NaN]	-9	hSpCas9	negative selection	9666059
179570136	179570159	3	+	27869803	HPAFII	viability after 15 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.9342702467726922	[281]	[165,153,NaN]	-7	hSpCas9	negative selection	9666060
179570180	179570203	3	+	27869803	HPAFII	viability after 15 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	0.0785730532453206	[54]	[83,48,NaN]	0	hSpCas9	negative selection	9666061
179576281	179576304	3	-	27869803	HPAFII	viability after 15 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-0.4131822467200158	[220]	[342,75,NaN]	-4	hSpCas9	negative selection	9666062
179576290	179576313	3	+	27869803	HPAFII	viability after 15 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.3070670208594288	[135]	[100,32,NaN]	-8	hSpCas9	negative selection	9666063
179580961	179580984	3	+	27869803	HPAFII	viability after 15 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-3.7324461296515192	[80]	[0,9,NaN]	-9	hSpCas9	negative selection	9666064
179569853	179569876	3	+	27869803	ASPC1	viability after 36 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-0.4028818808527034	[563]	[310,58,104]	-4	hSpCas9	negative selection	9748508
179570136	179570159	3	+	27869803	ASPC1	viability after 36 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.3936339300469216	[437]	[161,137,65]	-4	hSpCas9	negative selection	9748509
179570180	179570203	3	+	27869803	ASPC1	viability after 36 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	1.9796549995399055	[141]	[465,53,115]	9	hSpCas9	negative selection	9748510
179576281	179576304	3	-	27869803	ASPC1	viability after 36 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	0.622051749622505	[530]	[258,197,369]	6	hSpCas9	negative selection	9748511
179576290	179576313	3	+	27869803	ASPC1	viability after 36 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-0.7771735715200883	[592]	[246,87,56]	-6	hSpCas9	negative selection	9748512
179580961	179580984	3	+	27869803	ASPC1	viability after 36 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	0.4811466991436142	[204]	[153,134,32]	5	hSpCas9	negative selection	9748513
179569853	179569876	3	+	27869803	PATU8988S	viability after 35 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-3.4425545550645493	[418]	[24,5,NaN]	-9	hSpCas9	negative selection	9830957
179570136	179570159	3	+	27869803	PATU8988S	viability after 35 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.24631319674361402	[507]	[165,178,NaN]	-3	hSpCas9	negative selection	9830958
179570180	179570203	3	+	27869803	PATU8988S	viability after 35 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	0.48365750937270424	[118]	[73,59,NaN]	5	hSpCas9	negative selection	9830959
179576281	179576304	3	-	27869803	PATU8988S	viability after 35 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.1554620773424935	[616]	[135,86,NaN]	-8	hSpCas9	negative selection	9830960
179576290	179576313	3	+	27869803	PATU8988S	viability after 35 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.9044189554348798	[413]	[61,26,NaN]	-9	hSpCas9	negative selection	9830961
179580961	179580984	3	+	27869803	PATU8988S	viability after 35 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-4.12618435057692	[151]	[5,0,NaN]	-9	hSpCas9	negative selection	9830962
179569853	179569876	3	+	27869803	PATU8988S	viability after 31 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-3.868335533813148	[418]	[10,11,NaN]	-9	hSpCas9	negative selection	9913406
179570136	179570159	3	+	27869803	PATU8988S	viability after 31 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.24606865346818707	[507]	[161,181,NaN]	-3	hSpCas9	negative selection	9913407
179570180	179570203	3	+	27869803	PATU8988S	viability after 31 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	0.16928959439978009	[118]	[44,63,NaN]	2	hSpCas9	negative selection	9913408
179576281	179576304	3	-	27869803	PATU8988S	viability after 31 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.1394875227361918	[616]	[90,137,NaN]	-8	hSpCas9	negative selection	9913409
179576290	179576313	3	+	27869803	PATU8988S	viability after 31 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-1.1914716297749681	[413]	[77,64,NaN]	-8	hSpCas9	negative selection	9913410
179580961	179580984	3	+	27869803	PATU8988S	viability after 31 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-3.658289613543513	[151]	[6,1,NaN]	-9	hSpCas9	negative selection	9913411
179569853	179569876	3	+	27869803	HPAFII	viability after 35 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-7.21758379183969	[293]	[0,0,NaN]	-9	hSpCas9	negative selection	9995855
179570136	179570159	3	+	27869803	HPAFII	viability after 35 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.5050783382460085	[281]	[109,89,NaN]	-3	hSpCas9	negative selection	9995856
179570180	179570203	3	+	27869803	HPAFII	viability after 35 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-1.8309800202553221	[54]	[12,1,NaN]	-7	hSpCas9	negative selection	9995857
179576281	179576304	3	-	27869803	HPAFII	viability after 35 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-1.9768308867187776	[220]	[50,2,NaN]	-7	hSpCas9	negative selection	9995858
179576290	179576313	3	+	27869803	HPAFII	viability after 35 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-2.2923282541182046	[135]	[6,21,NaN]	-8	hSpCas9	negative selection	9995859
179580961	179580984	3	+	27869803	HPAFII	viability after 35 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-5.35776144988795	[80]	[0,0,NaN]	-9	hSpCas9	negative selection	9995860
179569853	179569876	3	+	27869803	HPAFII	viability after 31 days	GGATCCTATACTGTGAGAGCTGG	ACTL6A	ENSG00000136518	-4.71915112966134	[293]	[0,11,NaN]	-9	hSpCas9	negative selection	10078304
179570136	179570159	3	+	27869803	HPAFII	viability after 31 days	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.831720931599476	[281]	[75,102,NaN]	-5	hSpCas9	negative selection	10078305
179570180	179570203	3	+	27869803	HPAFII	viability after 31 days	TAATGCTCTGCGTGTTCCGAGGG	ACTL6A	ENSG00000136518	-0.4602633031424035	[54]	[20,23,NaN]	-3	hSpCas9	negative selection	10078306
179576281	179576304	3	-	27869803	HPAFII	viability after 31 days	AGGACATAGCCATCGTGGACTGG	ACTL6A	ENSG00000136518	-3.002330938567467	[220]	[14,15,NaN]	-8	hSpCas9	negative selection	10078307
179576290	179576313	3	+	27869803	HPAFII	viability after 31 days	GATGGCTATGTCCTTCAACAAGG	ACTL6A	ENSG00000136518	-2.895534624696997	[135]	[15,3,NaN]	-8	hSpCas9	negative selection	10078308
179580961	179580984	3	+	27869803	HPAFII	viability after 31 days	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-3.385463402248001	[80]	[0,7,NaN]	-9	hSpCas9	negative selection	10078309
179586571	179586594	3	+	28162770	P31FUJ	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-5.590354209032462	[40]	[0]	-9	hSpCas9	negative selection	10106387
179570091	179570114	3	+	28162770	P31FUJ	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.4387768663168639	[465]	[201]	-7	hSpCas9	negative selection	10106388
179576272	179576295	3	+	28162770	P31FUJ	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-2.3530964381320905	[299]	[68]	-8	hSpCas9	negative selection	10106389
179581173	179581196	3	+	28162770	P31FUJ	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.1650240899795188	[394]	[206]	-7	hSpCas9	negative selection	10106390
179570136	179570159	3	+	28162770	P31FUJ	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.4551946257508264	[27]	[11]	-7	hSpCas9	negative selection	10106391
179573446	179573469	3	-	28162770	P31FUJ	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-3.130922590395165	[409]	[54]	-9	hSpCas9	negative selection	10106392
179574430	179574453	3	-	28162770	P31FUJ	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	0.20213485230216988	[107]	[145]	2	hSpCas9	negative selection	10106393
179576634	179576657	3	-	28162770	P31FUJ	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-1.7662344044954525	[549]	[189]	-8	hSpCas9	negative selection	10106394
179580961	179580984	3	+	28162770	P31FUJ	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.9194945920993614	[234]	[72]	-8	hSpCas9	negative selection	10106395
179586571	179586594	3	+	28162770	TF1	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10275753
179570091	179570114	3	+	28162770	TF1	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10275754
179576272	179576295	3	+	28162770	TF1	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10275755
179581173	179581196	3	+	28162770	TF1	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10275756
179570136	179570159	3	+	28162770	TF1	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10275757
179573446	179573469	3	-	28162770	TF1	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10275758
179574430	179574453	3	-	28162770	TF1	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10275759
179576634	179576657	3	-	28162770	TF1	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10275760
179580961	179580984	3	+	28162770	TF1	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10275761
179586571	179586594	3	+	28162770	SKM1	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-4.143929792909368	[9]	[0]	-9	hSpCas9	negative selection	10445119
179570091	179570114	3	+	28162770	SKM1	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.0225346853947141	[130]	[113]	-6	hSpCas9	negative selection	10445120
179576272	179576295	3	+	28162770	SKM1	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-3.226391953101341	[89]	[16]	-9	hSpCas9	negative selection	10445121
179581173	179581196	3	+	28162770	SKM1	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.3031283877586217	[133]	[95]	-7	hSpCas9	negative selection	10445122
179570136	179570159	3	+	28162770	SKM1	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-2.237039197300849	[7]	[2]	-8	hSpCas9	negative selection	10445123
179573446	179573469	3	-	28162770	SKM1	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-3.803854351311746	[78]	[9]	-9	hSpCas9	negative selection	10445124
179574430	179574453	3	-	28162770	SKM1	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-2.031455063650955	[36]	[15]	-8	hSpCas9	negative selection	10445125
179576634	179576657	3	-	28162770	SKM1	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-2.3638954768512757	[98]	[33]	-8	hSpCas9	negative selection	10445126
179580961	179580984	3	+	28162770	SKM1	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.1532076064973786	[38]	[30]	-7	hSpCas9	negative selection	10445127
179586571	179586594	3	+	28162770	SKM1	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-4.143929792909368	[9]	[0]	-9	hSpCas9	negative selection	10614485
179570091	179570114	3	+	28162770	SKM1	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.0225346853947141	[130]	[113]	-6	hSpCas9	negative selection	10614486
179576272	179576295	3	+	28162770	SKM1	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-3.226391953101341	[89]	[16]	-9	hSpCas9	negative selection	10614487
179581173	179581196	3	+	28162770	SKM1	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.3031283877586217	[133]	[95]	-7	hSpCas9	negative selection	10614488
179570136	179570159	3	+	28162770	SKM1	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-2.237039197300849	[7]	[2]	-8	hSpCas9	negative selection	10614489
179573446	179573469	3	-	28162770	SKM1	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-3.803854351311746	[78]	[9]	-9	hSpCas9	negative selection	10614490
179574430	179574453	3	-	28162770	SKM1	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-2.031455063650955	[36]	[15]	-8	hSpCas9	negative selection	10614491
179576634	179576657	3	-	28162770	SKM1	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-2.3638954768512757	[98]	[33]	-8	hSpCas9	negative selection	10614492
179580961	179580984	3	+	28162770	SKM1	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.1532076064973786	[38]	[30]	-7	hSpCas9	negative selection	10614493
179586571	179586594	3	+	28162770	PL21	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-4.291713481840355	[44]	[0]	-9	hSpCas9	negative selection	10783851
179570091	179570114	3	+	28162770	PL21	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-0.7502024992033686	[513]	[132]	-5	hSpCas9	negative selection	10783852
179576272	179576295	3	+	28162770	PL21	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-0.913876645802336	[328]	[75]	-6	hSpCas9	negative selection	10783853
179581173	179581196	3	+	28162770	PL21	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.4899049322893936	[483]	[74]	-7	hSpCas9	negative selection	10783854
179570136	179570159	3	+	28162770	PL21	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-0.5547478876741483	[26]	[7]	-4	hSpCas9	negative selection	10783855
179573446	179573469	3	-	28162770	PL21	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-3.1217884803980422	[239]	[11]	-9	hSpCas9	negative selection	10783856
179574430	179574453	3	-	28162770	PL21	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	1.2781421264905932	[71]	[75]	9	hSpCas9	negative selection	10783857
179576634	179576657	3	-	28162770	PL21	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-1.1116286141778207	[282]	[56]	-6	hSpCas9	negative selection	10783858
179580961	179580984	3	+	28162770	PL21	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.6623568617607447	[159]	[21]	-8	hSpCas9	negative selection	10783859
179586571	179586594	3	+	28162770	P31FUJ	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-5.590354209032462	[40]	[0]	-9	hSpCas9	negative selection	10953217
179570091	179570114	3	+	28162770	P31FUJ	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.4387768663168639	[465]	[201]	-7	hSpCas9	negative selection	10953218
179576272	179576295	3	+	28162770	P31FUJ	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-2.3530964381320905	[299]	[68]	-8	hSpCas9	negative selection	10953219
179581173	179581196	3	+	28162770	P31FUJ	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.1650240899795188	[394]	[206]	-7	hSpCas9	negative selection	10953220
179570136	179570159	3	+	28162770	P31FUJ	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.4551946257508264	[27]	[11]	-7	hSpCas9	negative selection	10953221
179573446	179573469	3	-	28162770	P31FUJ	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-3.130922590395165	[409]	[54]	-9	hSpCas9	negative selection	10953222
179574430	179574453	3	-	28162770	P31FUJ	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	0.20213485230216988	[107]	[145]	2	hSpCas9	negative selection	10953223
179576634	179576657	3	-	28162770	P31FUJ	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-1.7662344044954525	[549]	[189]	-8	hSpCas9	negative selection	10953224
179580961	179580984	3	+	28162770	P31FUJ	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.9194945920993614	[234]	[72]	-8	hSpCas9	negative selection	10953225
179586571	179586594	3	+	28162770	OCIAML5	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-3.6594214929216013	[13]	[1]	-9	hSpCas9	negative selection	11122583
179570091	179570114	3	+	28162770	OCIAML5	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.3354910451230912	[287]	[205]	-6	hSpCas9	negative selection	11122584
179576272	179576295	3	+	28162770	OCIAML5	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-1.7395918416055844	[147]	[79]	-7	hSpCas9	negative selection	11122585
179581173	179581196	3	+	28162770	OCIAML5	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.6188673945709664	[227]	[133]	-7	hSpCas9	negative selection	11122586
179570136	179570159	3	+	28162770	OCIAML5	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-4.173994665751359	[19]	[1]	-9	hSpCas9	negative selection	11122587
179573446	179573469	3	-	28162770	OCIAML5	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-4.570884818319944	[236]	[17]	-9	hSpCas9	negative selection	11122588
179574430	179574453	3	-	28162770	OCIAML5	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-0.2729096918240467	[82]	[123]	-2	hSpCas9	negative selection	11122589
179576634	179576657	3	-	28162770	OCIAML5	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-1.741035258475253	[349]	[188]	-7	hSpCas9	negative selection	11122590
179580961	179580984	3	+	28162770	OCIAML5	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.8849811933367322	[132]	[64]	-7	hSpCas9	negative selection	11122591
179586571	179586594	3	+	28162770	EOL1	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-0.8556710205495555	[78]	[22]	-5	hSpCas9	negative selection	11291949
179570091	179570114	3	+	28162770	EOL1	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-0.7312713266949752	[771]	[244]	-5	hSpCas9	negative selection	11291950
179576272	179576295	3	+	28162770	EOL1	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-2.100987320536603	[569]	[69]	-8	hSpCas9	negative selection	11291951
179581173	179581196	3	+	28162770	EOL1	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-0.6305132434367595	[763]	[259]	-4	hSpCas9	negative selection	11291952
179570136	179570159	3	+	28162770	EOL1	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	2.0806669734878165	[34]	[77]	9	hSpCas9	negative selection	11291953
179573446	179573469	3	-	28162770	EOL1	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-4.522535454639118	[348]	[7]	-9	hSpCas9	negative selection	11291954
179574430	179574453	3	-	28162770	EOL1	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	0.7749714155200247	[131]	[118]	6	hSpCas9	negative selection	11291955
179576634	179576657	3	-	28162770	EOL1	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-0.1781903340187238	[450]	[209]	-1	hSpCas9	negative selection	11291956
179580961	179580984	3	+	28162770	EOL1	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-1.7320757142780678	[226]	[35]	-8	hSpCas9	negative selection	11291957
179586571	179586594	3	+	28162770	MOLM13	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-5.7020356198977336	[71]	[0]	-9	hSpCas9	negative selection	11461315
179570091	179570114	3	+	28162770	MOLM13	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	0.5990253884722412	[577]	[632]	4	hSpCas9	negative selection	11461316
179576272	179576295	3	+	28162770	MOLM13	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-2.462131088902495	[502]	[65]	-8	hSpCas9	negative selection	11461317
179581173	179581196	3	+	28162770	MOLM13	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-5.066830364396956	[648]	[13]	-9	hSpCas9	negative selection	11461318
179570136	179570159	3	+	28162770	MOLM13	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-3.023963714785096	[44]	[3]	-8	hSpCas9	negative selection	11461319
179573446	179573469	3	-	28162770	MOLM13	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-8.256624471575371	[422]	[0]	-9	hSpCas9	negative selection	11461320
179574430	179574453	3	-	28162770	MOLM13	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-1.3163819273999837	[154]	[44]	-6	hSpCas9	negative selection	11461321
179576634	179576657	3	-	28162770	MOLM13	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-2.187776110519779	[459]	[72]	-7	hSpCas9	negative selection	11461322
179580961	179580984	3	+	28162770	MOLM13	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.3435010537481817	[357]	[50]	-8	hSpCas9	negative selection	11461323
179586571	179586594	3	+	28162770	HEL	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-5.2399042173614845	[58]	[0]	-9	hSpCas9	negative selection	11630681
179570091	179570114	3	+	28162770	HEL	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	0.30821070033336095	[574]	[455]	2	hSpCas9	negative selection	11630682
179576272	179576295	3	+	28162770	HEL	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-4.5470857268796605	[437]	[11]	-9	hSpCas9	negative selection	11630683
179581173	179581196	3	+	28162770	HEL	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-3.951809717549997	[603]	[24]	-9	hSpCas9	negative selection	11630684
179570136	179570159	3	+	28162770	HEL	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-4.783525922701741	[42]	[0]	-9	hSpCas9	negative selection	11630685
179573446	179573469	3	-	28162770	HEL	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-4.67195769365593	[397]	[9]	-9	hSpCas9	negative selection	11630686
179574430	179574453	3	-	28162770	HEL	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	1.1596559452984145	[122]	[175]	8	hSpCas9	negative selection	11630687
179576634	179576657	3	-	28162770	HEL	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-0.9628045461432511	[352]	[115]	-5	hSpCas9	negative selection	11630688
179580961	179580984	3	+	28162770	HEL	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-3.7681942689457504	[233]	[10]	-9	hSpCas9	negative selection	11630689
179586571	179586594	3	+	28162770	MV411	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-2.074490544104587	[59]	[11]	-8	hSpCas9	negative selection	11800047
179570091	179570114	3	+	28162770	MV411	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.119026444706424	[476]	[184]	-6	hSpCas9	negative selection	11800048
179576272	179576295	3	+	28162770	MV411	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-0.6484052179259326	[373]	[200]	-4	hSpCas9	negative selection	11800049
179581173	179581196	3	+	28162770	MV411	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.012530552003235	[375]	[156]	-6	hSpCas9	negative selection	11800050
179570136	179570159	3	+	28162770	MV411	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.5074499513806932	[26]	[7]	-7	hSpCas9	negative selection	11800051
179573446	179573469	3	-	28162770	MV411	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-1.9620158148461746	[295]	[63]	-8	hSpCas9	negative selection	11800052
179574430	179574453	3	-	28162770	MV411	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-0.9907221864119893	[91]	[38]	-6	hSpCas9	negative selection	11800053
179576634	179576657	3	-	28162770	MV411	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-1.7650895470933876	[346]	[85]	-8	hSpCas9	negative selection	11800054
179580961	179580984	3	+	28162770	MV411	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-0.7182109444264478	[165]	[84]	-5	hSpCas9	negative selection	11800055
179586571	179586594	3	+	28162770	MONOMAC1	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-1.8344667676748454	[27]	[8]	-8	hSpCas9	negative selection	11969413
179570091	179570114	3	+	28162770	MONOMAC1	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.6370510118696102	[368]	[135]	-8	hSpCas9	negative selection	11969414
179576272	179576295	3	+	28162770	MONOMAC1	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-2.3954504054615615	[178]	[38]	-9	hSpCas9	negative selection	11969415
179581173	179581196	3	+	28162770	MONOMAC1	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-2.4884996612198647	[327]	[66]	-9	hSpCas9	negative selection	11969416
179570136	179570159	3	+	28162770	MONOMAC1	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-4.0043917691171576	[13]	[0]	-9	hSpCas9	negative selection	11969417
179573446	179573469	3	-	28162770	MONOMAC1	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-1.9118796303276195	[150]	[45]	-8	hSpCas9	negative selection	11969418
179574430	179574453	3	-	28162770	MONOMAC1	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-1.0335381147766742	[49]	[27]	-7	hSpCas9	negative selection	11969419
179576634	179576657	3	-	28162770	MONOMAC1	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-1.8087662573434953	[271]	[88]	-8	hSpCas9	negative selection	11969420
179580961	179580984	3	+	28162770	MONOMAC1	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	0.5514243859444818	[99]	[167]	5	hSpCas9	negative selection	11969421
179586571	179586594	3	+	28162770	OCIAML2	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-1.8856673245210054	[3]	[5]	-8	hSpCas9	negative selection	12138779
179570091	179570114	3	+	28162770	OCIAML2	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-0.770190107101069	[91]	[298]	-5	hSpCas9	negative selection	12138780
179576272	179576295	3	+	28162770	OCIAML2	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-1.7448047886811557	[51]	[85]	-8	hSpCas9	negative selection	12138781
179581173	179581196	3	+	28162770	OCIAML2	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-1.932209910458035	[83]	[121]	-8	hSpCas9	negative selection	12138782
179570136	179570159	3	+	28162770	OCIAML2	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-2.248237403905714	[5]	[6]	-8	hSpCas9	negative selection	12138783
179573446	179573469	3	-	28162770	OCIAML2	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-2.424087239305131	[60]	[62]	-8	hSpCas9	negative selection	12138784
179574430	179574453	3	-	28162770	OCIAML2	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	-0.5879867758803201	[31]	[117]	-4	hSpCas9	negative selection	12138785
179576634	179576657	3	-	28162770	OCIAML2	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-1.0971714297147168	[65]	[170]	-6	hSpCas9	negative selection	12138786
179580961	179580984	3	+	28162770	OCIAML2	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-2.1144860150168863	[24]	[31]	-8	hSpCas9	negative selection	12138787
179586571	179586594	3	+	28162770	OCIAML3	viability	ATAATACAACAGTGGAACGGAGG	ACTL6A	ENSG00000136518	-0.31389972113142806	[6]	[16]	-2	hSpCas9	negative selection	12308145
179570091	179570114	3	+	28162770	OCIAML3	viability	ATGGTGGTAGAAAGAGATGACGG	ACTL6A	ENSG00000136518	-1.926204070665353	[140]	[111]	-8	hSpCas9	negative selection	12308146
179576272	179576295	3	+	28162770	OCIAML3	viability	ACTGCAATTCCAGTCCACGATGG	ACTL6A	ENSG00000136518	-3.2747291238507503	[108]	[33]	-9	hSpCas9	negative selection	12308147
179581173	179581196	3	+	28162770	OCIAML3	viability	CATGTTGTCACCACAAGTGTTGG	ACTL6A	ENSG00000136518	-0.9132861567975761	[135]	[217]	-6	hSpCas9	negative selection	12308148
179570136	179570159	3	+	28162770	OCIAML3	viability	GGCGATAAAGGCAAACAAGGCGG	ACTL6A	ENSG00000136518	-1.5940076403241634	[7]	[7]	-8	hSpCas9	negative selection	12308149
179573446	179573469	3	-	28162770	OCIAML3	viability	GGTGCCTCTGACATGAGAACAGG	ACTL6A	ENSG00000136518	-2.816400061660611	[90]	[38]	-9	hSpCas9	negative selection	12308150
179574430	179574453	3	-	28162770	OCIAML3	viability	GTTTTGCAAAGGAAGAAGGCAGG	ACTL6A	ENSG00000136518	1.3376053846955869	[26]	[205]	9	hSpCas9	negative selection	12308151
179576634	179576657	3	-	28162770	OCIAML3	viability	GTAATAAAGTCTCCAGCAAGAGG	ACTL6A	ENSG00000136518	-3.733937901468638	[118]	[26]	-9	hSpCas9	negative selection	12308152
179580961	179580984	3	+	28162770	OCIAML3	viability	GAGCGGCTAAAGATTCCAGAAGG	ACTL6A	ENSG00000136518	-0.1651643415202888	[25]	[69]	-1	hSpCas9	negative selection	12308153