Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:51412
• Symbol:ACTL6B
• Description:actin like 6B

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTL6B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
100655554	100655577	7	+	26472758	Jiyoye	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.17013354667184732	[93]	[62]	-1	hSpCas9	negative selection	2080
100655828	100655851	7	-	26472758	Jiyoye	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.032356679693719026	[98]	[72]	0	hSpCas9	negative selection	2081
100655456	100655479	7	-	26472758	Jiyoye	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	1.030870276715744	[97]	[150]	6	hSpCas9	negative selection	2082
100655020	100655043	7	+	26472758	Jiyoye	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.4175919974512119	[137]	[138]	3	hSpCas9	negative selection	2083
100648765	100648788	7	-	26472758	Jiyoye	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.10761509964696558	[335]	[272]	0	hSpCas9	negative selection	2084
100648626	100648649	7	+	26472758	Jiyoye	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	2.2096148131493614	[83]	[292]	9	hSpCas9	negative selection	2085
100647476	100647499	7	-	26472758	Jiyoye	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.6295678028423215	[95]	[111]	4	hSpCas9	negative selection	2086
100646997	100647020	7	-	26472758	Jiyoye	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.5321336519366949	[209]	[228]	4	hSpCas9	negative selection	2087
100646615	100646638	7	-	26472758	Jiyoye	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	2088
100655871	100655894	7	-	26472758	Jiyoye	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	5.53645839845084	[0]	[34]	9	hSpCas9	negative selection	2089
100655554	100655577	7	+	26472758	KBM7	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.5846430774840783	[278,290]	[61,114]	-5	hSpCas9	negative selection	193198
100655828	100655851	7	-	26472758	KBM7	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	1.0931457752181897	[400,352]	[338,411]	9	hSpCas9	negative selection	193199
100655456	100655479	7	-	26472758	KBM7	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	0.18753799128803872	[802,669]	[389,394]	2	hSpCas9	negative selection	193200
100655020	100655043	7	+	26472758	KBM7	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.2557303069221116	[579,475]	[372,224]	2	hSpCas9	negative selection	193201
100648765	100648788	7	-	26472758	KBM7	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.3585632704669929	[949,714]	[542,455]	4	hSpCas9	negative selection	193202
100648626	100648649	7	+	26472758	KBM7	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	-0.0021434975394327704	[642,307]	[276,161]	0	hSpCas9	negative selection	193203
100647476	100647499	7	-	26472758	KBM7	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.5647006426175638	[560,403]	[206,442]	6	hSpCas9	negative selection	193204
100646997	100647020	7	-	26472758	KBM7	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.2351973047733339	[793,650]	[373,418]	2	hSpCas9	negative selection	193205
100646615	100646638	7	-	26472758	KBM7	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-0.3905695532923259	[42,16]	[3,15]	-4	hSpCas9	negative selection	193206
100655871	100655894	7	-	26472758	KBM7	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	-1.5445423415724144	[182,130]	[24,24]	-8	hSpCas9	negative selection	193207
100655554	100655577	7	+	26472758	Raji	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.725506478791142	[170]	[23]	-5	hSpCas9	negative selection	384316
100655828	100655851	7	-	26472758	Raji	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.4455522712681729	[211]	[66]	4	hSpCas9	negative selection	384317
100655456	100655479	7	-	26472758	Raji	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	0.2717703532744819	[231]	[64]	2	hSpCas9	negative selection	384318
100655020	100655043	7	+	26472758	Raji	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.6019597996376502	[246]	[86]	5	hSpCas9	negative selection	384319
100648765	100648788	7	-	26472758	Raji	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	1.4332588147776246	[291]	[182]	9	hSpCas9	negative selection	384320
100648626	100648649	7	+	26472758	Raji	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	-0.3926900677610437	[395]	[69]	-3	hSpCas9	negative selection	384321
100647476	100647499	7	-	26472758	Raji	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.303018655921807	[240]	[68]	3	hSpCas9	negative selection	384322
100646997	100647020	7	-	26472758	Raji	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.7216403428887939	[519]	[198]	6	hSpCas9	negative selection	384323
100646615	100646638	7	-	26472758	Raji	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	1.785455440486237	[24]	[19]	9	hSpCas9	negative selection	384324
100655871	100655894	7	-	26472758	Raji	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	-0.3901161240972173	[95]	[16]	-3	hSpCas9	negative selection	384325
100655554	100655577	7	+	26472758	K562	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.9498500927556132	[253]	[110]	-5	hSpCas9	negative selection	575434
100655828	100655851	7	-	26472758	K562	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.18759185021611047	[227]	[168]	-1	hSpCas9	negative selection	575435
100655456	100655479	7	-	26472758	K562	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	0.5102572063769433	[513]	[617]	4	hSpCas9	negative selection	575436
100655020	100655043	7	+	26472758	K562	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.5185936911054411	[472]	[571]	4	hSpCas9	negative selection	575437
100648765	100648788	7	-	26472758	K562	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.34698846130699457	[664]	[713]	2	hSpCas9	negative selection	575438
100648626	100648649	7	+	26472758	K562	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	-1.4012978041338053	[387]	[123]	-6	hSpCas9	negative selection	575439
100647476	100647499	7	-	26472758	K562	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.15336674753854382	[326]	[306]	1	hSpCas9	negative selection	575440
100646997	100647020	7	-	26472758	K562	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.17787787165605073	[598]	[571]	1	hSpCas9	negative selection	575441
100646615	100646638	7	-	26472758	K562	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	0.9643108084737115	[50]	[83]	7	hSpCas9	negative selection	575442
100655871	100655894	7	-	26472758	K562	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	-0.9422819865266923	[172]	[75]	-5	hSpCas9	negative selection	575443
100648808	100648831	7	-	26627737	DLD1	viability	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-1.2487721267412506	[560]	[69,27,114]	-8	hSpCas9	negative selection	834151
100650049	100650072	7	+	26627737	DLD1	viability	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	1.2302127673564995	[182]	[60,169,167]	9	hSpCas9	negative selection	834152
100655101	100655124	7	+	26627737	DLD1	viability	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.5351384540120196	[424]	[65,122,87]	-5	hSpCas9	negative selection	834153
100655451	100655474	7	-	26627737	DLD1	viability	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.3241105463663141	[501]	[191,55,124]	-3	hSpCas9	negative selection	834154
100655819	100655842	7	-	26627737	DLD1	viability	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	-0.20040741118106897	[1105]	[367,308,235]	-2	hSpCas9	negative selection	834155
100656346	100656369	7	-	26627737	DLD1	viability	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	0.14945521913696705	[549]	[172,203,194]	1	hSpCas9	negative selection	834156
100648808	100648831	7	-	26627737	GBM cells	viability after 5 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.6967835882798508	[217]	[198,179]	8	hSpCas9	negative selection	916466
100650049	100650072	7	+	26627737	GBM cells	viability after 5 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.3234785464507622	[300]	[115,141]	-5	hSpCas9	negative selection	916467
100655101	100655124	7	+	26627737	GBM cells	viability after 5 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.2338413339660862	[181]	[109,55]	-4	hSpCas9	negative selection	916468
100655451	100655474	7	-	26627737	GBM cells	viability after 5 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.16710998583525824	[185]	[98,124]	2	hSpCas9	negative selection	916469
100655819	100655842	7	-	26627737	GBM cells	viability after 5 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.41314186406960784	[417]	[297,298]	6	hSpCas9	negative selection	916470
100656346	100656369	7	-	26627737	GBM cells	viability after 5 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.41821323373785574	[374]	[168,131]	-6	hSpCas9	negative selection	916471
100648808	100648831	7	-	26627737	GBM cells	viability after 13 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.6709882521766257	[217]	[216,164]	7	hSpCas9	negative selection	998781
100650049	100650072	7	+	26627737	GBM cells	viability after 13 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.16532947048790186	[300]	[170,124]	-2	hSpCas9	negative selection	998782
100655101	100655124	7	+	26627737	GBM cells	viability after 13 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-1.0869890379660898	[181]	[51,41]	-8	hSpCas9	negative selection	998783
100655451	100655474	7	-	26627737	GBM cells	viability after 13 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.4293147349021339	[185]	[136,134]	5	hSpCas9	negative selection	998784
100655819	100655842	7	-	26627737	GBM cells	viability after 13 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.5054631905087796	[417]	[300,338]	6	hSpCas9	negative selection	998785
100656346	100656369	7	-	26627737	GBM cells	viability after 13 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.9059196654093611	[374]	[112,104]	-8	hSpCas9	negative selection	998786
100648808	100648831	7	-	26627737	GBM cells	viability after 21 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.9917683534420756	[217]	[234,235]	8	hSpCas9	negative selection	1081096
100650049	100650072	7	+	26627737	GBM cells	viability after 21 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.19110587826702846	[300]	[193,179]	2	hSpCas9	negative selection	1081097
100655101	100655124	7	+	26627737	GBM cells	viability after 21 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-1.1190622594324116	[181]	[44,45]	-7	hSpCas9	negative selection	1081098
100655451	100655474	7	-	26627737	GBM cells	viability after 21 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.5411829563947397	[185]	[145,147]	5	hSpCas9	negative selection	1081099
100655819	100655842	7	-	26627737	GBM cells	viability after 21 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.9637113545327298	[417]	[456,429]	8	hSpCas9	negative selection	1081100
100656346	100656369	7	-	26627737	GBM cells	viability after 21 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-1.324344523792714	[374]	[72,88]	-8	hSpCas9	negative selection	1081101
100648808	100648831	7	-	26627737	RPE1	viability after 9 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.5671634001202034	[779]	[228,81]	-4	hSpCas9	negative selection	1163411
100650049	100650072	7	+	26627737	RPE1	viability after 9 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.9347748313553538	[537]	[338,299]	6	hSpCas9	negative selection	1163412
100655101	100655124	7	+	26627737	RPE1	viability after 9 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.06133659571638472	[630]	[163,221]	0	hSpCas9	negative selection	1163413
100655451	100655474	7	-	26627737	RPE1	viability after 9 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	1.7102796214544607	[335]	[262,448]	8	hSpCas9	negative selection	1163414
100655819	100655842	7	-	26627737	RPE1	viability after 9 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.5640922942235551	[1605]	[886,557]	4	hSpCas9	negative selection	1163415
100656346	100656369	7	-	26627737	RPE1	viability after 9 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.6040362713200707	[1350]	[348,186]	-4	hSpCas9	negative selection	1163416
100648808	100648831	7	-	26627737	RPE1	viability after 12 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.12432551321401068	[779]	[251,128]	-1	hSpCas9	negative selection	1245726
100650049	100650072	7	+	26627737	RPE1	viability after 12 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	1.0467194043636923	[537]	[250,348]	6	hSpCas9	negative selection	1245727
100655101	100655124	7	+	26627737	RPE1	viability after 12 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.08603523252382528	[630]	[166,151]	0	hSpCas9	negative selection	1245728
100655451	100655474	7	-	26627737	RPE1	viability after 12 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	1.155665742645274	[335]	[204,196]	7	hSpCas9	negative selection	1245729
100655819	100655842	7	-	26627737	RPE1	viability after 12 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.3869911469519536	[1605]	[758,357]	2	hSpCas9	negative selection	1245730
100656346	100656369	7	-	26627737	RPE1	viability after 12 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.0744432694943995	[1350]	[368,318]	0	hSpCas9	negative selection	1245731
100648808	100648831	7	-	26627737	RPE1	viability after 15 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.06664957608801503	[779]	[340,84]	0	hSpCas9	negative selection	1328041
100650049	100650072	7	+	26627737	RPE1	viability after 15 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	1.1069027933478284	[537]	[395,261]	6	hSpCas9	negative selection	1328042
100655101	100655124	7	+	26627737	RPE1	viability after 15 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	0.3070618956812029	[630]	[173,265]	2	hSpCas9	negative selection	1328043
100655451	100655474	7	-	26627737	RPE1	viability after 15 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	1.4398994332811963	[335]	[152,358]	7	hSpCas9	negative selection	1328044
100655819	100655842	7	-	26627737	RPE1	viability after 15 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.4964135241018066	[1605]	[1012,281]	3	hSpCas9	negative selection	1328045
100656346	100656369	7	-	26627737	RPE1	viability after 15 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.8383664645000518	[1350]	[340,90]	-5	hSpCas9	negative selection	1328046
100648808	100648831	7	-	26627737	RPE1	viability after 18 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.0499703308440655	[779]	[314,83]	0	hSpCas9	negative selection	1410356
100650049	100650072	7	+	26627737	RPE1	viability after 18 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	1.0081241166339188	[537]	[379,197]	6	hSpCas9	negative selection	1410357
100655101	100655124	7	+	26627737	RPE1	viability after 18 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	0.43226422769241624	[630]	[62,407]	2	hSpCas9	negative selection	1410358
100655451	100655474	7	-	26627737	RPE1	viability after 18 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	2.035884587809975	[335]	[337,407]	8	hSpCas9	negative selection	1410359
100655819	100655842	7	-	26627737	RPE1	viability after 18 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.3111498528292276	[1605]	[762,296]	2	hSpCas9	negative selection	1410360
100656346	100656369	7	-	26627737	RPE1	viability after 18 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.05575181347456759	[1350]	[518,170]	0	hSpCas9	negative selection	1410361
100648808	100648831	7	-	26627737	HeLa	viability after 8 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.13365390141053657	[353]	[64,159,252]	1	hSpCas9	negative selection	1492671
100650049	100650072	7	+	26627737	HeLa	viability after 8 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.3283984813642465	[287]	[256,64,170]	3	hSpCas9	negative selection	1492672
100655101	100655124	7	+	26627737	HeLa	viability after 8 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-1.4523237306525543	[404]	[113,23,65]	-9	hSpCas9	negative selection	1492673
100655451	100655474	7	-	26627737	HeLa	viability after 8 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.586133697042291	[204]	[184,123,105]	5	hSpCas9	negative selection	1492674
100655819	100655842	7	-	26627737	HeLa	viability after 8 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.3278025063239842	[567]	[369,177,389]	3	hSpCas9	negative selection	1492675
100656346	100656369	7	-	26627737	HeLa	viability after 8 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	1.1471632126298446	[164]	[151,82,234]	8	hSpCas9	negative selection	1492676
100648808	100648831	7	-	26627737	HeLa	viability after 12 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.439906579007448	[353]	[56,98,166]	-4	hSpCas9	negative selection	1574986
100650049	100650072	7	+	26627737	HeLa	viability after 12 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.2559720048675868	[287]	[246,98,87]	2	hSpCas9	negative selection	1574987
100655101	100655124	7	+	26627737	HeLa	viability after 12 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.44815824070426047	[404]	[59,86,222]	-4	hSpCas9	negative selection	1574988
100655451	100655474	7	-	26627737	HeLa	viability after 12 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	1.205173890974205	[204]	[248,143,199]	8	hSpCas9	negative selection	1574989
100655819	100655842	7	-	26627737	HeLa	viability after 12 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	1.2762206364799695	[567]	[715,425,582]	8	hSpCas9	negative selection	1574990
100656346	100656369	7	-	26627737	HeLa	viability after 12 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	1.8680633779383804	[164]	[225,362,144]	9	hSpCas9	negative selection	1574991
100648808	100648831	7	-	26627737	HeLa	viability after 15 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.10427656142788441	[353]	[44,155,207]	-1	hSpCas9	negative selection	1657301
100650049	100650072	7	+	26627737	HeLa	viability after 15 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.38065906323900467	[287]	[191,117,146]	3	hSpCas9	negative selection	1657302
100655101	100655124	7	+	26627737	HeLa	viability after 15 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.5982269029196563	[404]	[41,195,87]	-5	hSpCas9	negative selection	1657303
100655451	100655474	7	-	26627737	HeLa	viability after 15 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	1.0872366047327364	[204]	[171,194,163]	7	hSpCas9	negative selection	1657304
100655819	100655842	7	-	26627737	HeLa	viability after 15 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	1.2130871905959326	[567]	[764,367,466]	8	hSpCas9	negative selection	1657305
100656346	100656369	7	-	26627737	HeLa	viability after 15 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	1.4244739820822034	[164]	[237,159,138]	8	hSpCas9	negative selection	1657306
100648808	100648831	7	-	26627737	HeLa	viability after 18 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.10610961459967935	[353]	[29,128,207]	-1	hSpCas9	negative selection	1739616
100650049	100650072	7	+	26627737	HeLa	viability after 18 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.37192849177940746	[287]	[125,98,146]	3	hSpCas9	negative selection	1739617
100655101	100655124	7	+	26627737	HeLa	viability after 18 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.5726789768024265	[404]	[28,165,87]	-5	hSpCas9	negative selection	1739618
100655451	100655474	7	-	26627737	HeLa	viability after 18 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	1.1113841092724306	[204]	[119,162,163]	7	hSpCas9	negative selection	1739619
100655819	100655842	7	-	26627737	HeLa	viability after 18 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	1.2174235717556403	[567]	[508,313,466]	8	hSpCas9	negative selection	1739620
100656346	100656369	7	-	26627737	HeLa	viability after 18 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	1.404268686428188	[164]	[151,135,138]	8	hSpCas9	negative selection	1739621
100648808	100648831	7	-	26627737	HCT116	viability after 6 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.860693689761149	[620]	[97,220]	5	hSpCas9	negative selection	1821931
100650049	100650072	7	+	26627737	HCT116	viability after 6 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-2.710977559115054	[756]	[32,9]	-9	hSpCas9	negative selection	1821932
100655101	100655124	7	+	26627737	HCT116	viability after 6 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	0.8354131410113957	[338]	[58,114]	4	hSpCas9	negative selection	1821933
100655451	100655474	7	-	26627737	HCT116	viability after 6 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.048285790545918	[703]	[272,26]	0	hSpCas9	negative selection	1821934
100655819	100655842	7	-	26627737	HCT116	viability after 6 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.8109010984485128	[980]	[441,175]	4	hSpCas9	negative selection	1821935
100656346	100656369	7	-	26627737	HCT116	viability after 6 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.20103065841977608	[1626]	[246,208]	-1	hSpCas9	negative selection	1821936
100648808	100648831	7	-	26627737	HCT116	viability after 8 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.37032520400425534	[310]	[125,171,99]	-4	hSpCas9	negative selection	1904246
100650049	100650072	7	+	26627737	HCT116	viability after 8 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.5686074154820875	[192]	[182,163,126]	6	hSpCas9	negative selection	1904247
100655101	100655124	7	+	26627737	HCT116	viability after 8 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	0.5914445708875639	[102]	[121,32,101]	6	hSpCas9	negative selection	1904248
100655451	100655474	7	-	26627737	HCT116	viability after 8 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.0489257946340602	[291]	[142,218,104]	0	hSpCas9	negative selection	1904249
100655819	100655842	7	-	26627737	HCT116	viability after 8 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.6702096905097177	[452]	[464,342,384]	6	hSpCas9	negative selection	1904250
100656346	100656369	7	-	26627737	HCT116	viability after 8 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.3667426781727382	[486]	[235,193,194]	-4	hSpCas9	negative selection	1904251
100648808	100648831	7	-	26627737	HCT116	viability after 9 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.09876464271372937	[620]	[257,113]	0	hSpCas9	negative selection	1986561
100650049	100650072	7	+	26627737	HCT116	viability after 9 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-1.6685318302026448	[756]	[57,67]	-8	hSpCas9	negative selection	1986562
100655101	100655124	7	+	26627737	HCT116	viability after 9 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-3.006855138583532	[338]	[3,16]	-9	hSpCas9	negative selection	1986563
100655451	100655474	7	-	26627737	HCT116	viability after 9 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.2803312847876849	[703]	[70,220]	-2	hSpCas9	negative selection	1986564
100655819	100655842	7	-	26627737	HCT116	viability after 9 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.6064086028111915	[980]	[538,287]	4	hSpCas9	negative selection	1986565
100656346	100656369	7	-	26627737	HCT116	viability after 9 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	0.09793841950224724	[1626]	[307,588]	0	hSpCas9	negative selection	1986566
100648808	100648831	7	-	26627737	HCT116	viability after 12 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.4358109748519007	[310]	[66,70,227]	-5	hSpCas9	negative selection	2068876
100650049	100650072	7	+	26627737	HCT116	viability after 12 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.4172492047651625	[192]	[150,136,116]	4	hSpCas9	negative selection	2068877
100655101	100655124	7	+	26627737	HCT116	viability after 12 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	1.3608832208464918	[102]	[135,165,115]	9	hSpCas9	negative selection	2068878
100655451	100655474	7	-	26627737	HCT116	viability after 12 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.193165351003392	[291]	[121,174,233]	2	hSpCas9	negative selection	2068879
100655819	100655842	7	-	26627737	HCT116	viability after 12 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	1.2313166170721108	[452]	[539,457,677]	8	hSpCas9	negative selection	2068880
100656346	100656369	7	-	26627737	HCT116	viability after 12 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.6359130892959877	[486]	[86,208,205]	-6	hSpCas9	negative selection	2068881
100648808	100648831	7	-	26627737	HCT116	viability after 15 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.08353694804832958	[310]	[137,190,231]	0	hSpCas9	negative selection	2151191
100650049	100650072	7	+	26627737	HCT116	viability after 15 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.10957035748376531	[192]	[131,96,82]	-1	hSpCas9	negative selection	2151192
100655101	100655124	7	+	26627737	HCT116	viability after 15 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	0.07564816907016203	[102]	[100,51,38]	0	hSpCas9	negative selection	2151193
100655451	100655474	7	-	26627737	HCT116	viability after 15 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.5917631586598677	[291]	[113,96,122]	-6	hSpCas9	negative selection	2151194
100655819	100655842	7	-	26627737	HCT116	viability after 15 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.8845647321917278	[452]	[543,452,451]	7	hSpCas9	negative selection	2151195
100656346	100656369	7	-	26627737	HCT116	viability after 15 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.1710953695983023	[486]	[285,232,230]	-2	hSpCas9	negative selection	2151196
100648808	100648831	7	-	26627737	HCT116	viability after 18 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.20036443683638988	[310]	[117,128,278]	1	hSpCas9	negative selection	2233506
100650049	100650072	7	+	26627737	HCT116	viability after 18 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.45064780318606934	[192]	[132,129,118]	4	hSpCas9	negative selection	2233507
100655101	100655124	7	+	26627737	HCT116	viability after 18 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	1.0922055996547022	[102]	[86,83,150]	8	hSpCas9	negative selection	2233508
100655451	100655474	7	-	26627737	HCT116	viability after 18 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.2681512147084064	[291]	[65,143,140]	-2	hSpCas9	negative selection	2233509
100655819	100655842	7	-	26627737	HCT116	viability after 18 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	1.0833657840337338	[452]	[614,300,487]	8	hSpCas9	negative selection	2233510
100656346	100656369	7	-	26627737	HCT116	viability after 18 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.2715707415272822	[486]	[187,258,130]	-2	hSpCas9	negative selection	2233511
100655415	100655438	7	+	24336569	HL60	viability	CCTTACTCATGCCATTCTTGAGG	ACTL6B	ENSG00000077080	-0.9803094676813927	[949]	[1018]	-7	hSpCas9	negative selection	2246433
100655444	100655467	7	+	24336569	HL60	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.671819860120271	[669]	[889]	-6	hSpCas9	negative selection	2246434
100655451	100655474	7	-	24336569	HL60	viability	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.6305551364070789	[629]	[2063]	5	hSpCas9	negative selection	2246435
100655456	100655479	7	-	24336569	HL60	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.16179020025758217	[396]	[750]	-1	hSpCas9	negative selection	2246436
100655461	100655484	7	-	24336569	HL60	viability	CCAATGCCCTGCACGTGCCTCGG	ACTL6B	ENSG00000077080	1.0324815932492413	[434]	[1882]	7	hSpCas9	negative selection	2246437
100655472	100655495	7	+	24336569	HL60	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	0.6895946922057179	[643]	[2197]	6	hSpCas9	negative selection	2246438
100655543	100655566	7	-	24336569	HL60	viability	GGGCTGCTGGCCGCGGAGGAGGG	ACTL6B	ENSG00000077080	-0.5326421921701454	[511]	[748]	-5	hSpCas9	negative selection	2246439
100655818	100655841	7	-	24336569	HL60	viability	CAGTCCGCGCTGGGTACGCTGGG	ACTL6B	ENSG00000077080	0.7380586897980165	[758]	[2678]	6	hSpCas9	negative selection	2246440
100655824	100655847	7	+	24336569	HL60	viability	GTACCCAGCGCGGACTGAGAAGG	ACTL6B	ENSG00000077080	-0.018933245771911134	[823]	[1720]	0	hSpCas9	negative selection	2246441
100656346	100656369	7	-	24336569	HL60	viability	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.9479404277915068	[329]	[361]	-7	hSpCas9	negative selection	2246442
100655415	100655438	7	+	24336569	KBM7	viability	CCTTACTCATGCCATTCTTGAGG	ACTL6B	ENSG00000077080	0.8774749993251993	[460]	[2309]	7	hSpCas9	negative selection	2313610
100655444	100655467	7	+	24336569	KBM7	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-1.0350442044732087	[576]	[767]	-6	hSpCas9	negative selection	2313611
100655451	100655474	7	-	24336569	KBM7	viability	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.14365328904087038	[628]	[1552]	-1	hSpCas9	negative selection	2313612
100655456	100655479	7	-	24336569	KBM7	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.21413158670343885	[389]	[916]	-2	hSpCas9	negative selection	2313613
100655461	100655484	7	-	24336569	KBM7	viability	CCAATGCCCTGCACGTGCCTCGG	ACTL6B	ENSG00000077080	0.5434104280028826	[521]	[2074]	5	hSpCas9	negative selection	2313614
100655472	100655495	7	+	24336569	KBM7	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.9384673363892904	[793]	[1129]	-6	hSpCas9	negative selection	2313615
100655543	100655566	7	-	24336569	KBM7	viability	GGGCTGCTGGCCGCGGAGGAGGG	ACTL6B	ENSG00000077080	0.5827235636146433	[529]	[2164]	5	hSpCas9	negative selection	2313616
100655818	100655841	7	-	24336569	KBM7	viability	CAGTCCGCGCTGGGTACGCTGGG	ACTL6B	ENSG00000077080	0.3500644175288915	[723]	[2516]	3	hSpCas9	negative selection	2313617
100655824	100655847	7	+	24336569	KBM7	viability	GTACCCAGCGCGGACTGAGAAGG	ACTL6B	ENSG00000077080	-0.6231144170872698	[466]	[826]	-5	hSpCas9	negative selection	2313618
100656346	100656369	7	-	24336569	KBM7	viability	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	0.6661830785699903	[258]	[1120]	6	hSpCas9	negative selection	2313619
100651632	100651655	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTTCAGTGGCATGATCTAGG	ACTL6B	ENSG00000077080	1.2297289136301017	[14,21]	[11,6]	5	dCas9-VP64	positive selection	2407557
100651632	100651655	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTTCAGTGGCATGATCTAGG	ACTL6B	ENSG00000077080	3.145747458543453	[46,57]	[48,249]	9	dCas9-VP64	positive selection	2502812
100655456	100655479	7	-	27260157	DLD1	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-1.33656899125012	[]	[]	-7	hSpCas9	negative selection	2574021
100655817	100655840	7	-	27260157	DLD1	viability	AGTCCGCGCTGGGTACGCTGGGG	ACTL6B	ENSG00000077080	-0.630719073856552	[]	[]	-5	hSpCas9	negative selection	2578275
100655415	100655438	7	+	27260157	DLD1	viability	CCTTACTCATGCCATTCTTGAGG	ACTL6B	ENSG00000077080	-0.207204806603534	[]	[]	-1	hSpCas9	negative selection	2580133
100650114	100650137	7	-	27260157	DLD1	viability	GTGGAACACACGGGCCAAGCGGG	ACTL6B	ENSG00000077080	-0.210960218409212	[]	[]	-1	hSpCas9	negative selection	2585697
100655448	100655471	7	-	27260157	DLD1	viability	CGTGCCTCGGGATGGAGCGGAGG	ACTL6B	ENSG00000077080	-0.84326301261241	[]	[]	-6	hSpCas9	negative selection	2586805
100656346	100656369	7	-	27260157	DLD1	viability	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-2.06707903165722	[]	[]	-8	hSpCas9	negative selection	2610090
100650049	100650072	7	+	27260157	DLD1	viability	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.348939297401217	[]	[]	-3	hSpCas9	negative selection	2612212
100655824	100655847	7	+	27260157	DLD1	viability	GTACCCAGCGCGGACTGAGAAGG	ACTL6B	ENSG00000077080	-0.373344428566883	[]	[]	-3	hSpCas9	negative selection	2615125
100655058	100655081	7	+	27260157	DLD1	viability	AGACTTGACGTGTTTGCTGTAGG	ACTL6B	ENSG00000077080	-0.23162323325079	[]	[]	-2	hSpCas9	negative selection	2619008
100656344	100656367	7	-	27260157	DLD1	viability	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-1.7071853920773	[]	[]	-8	hSpCas9	negative selection	2619642
100655818	100655841	7	-	27260157	DLD1	viability	CAGTCCGCGCTGGGTACGCTGGG	ACTL6B	ENSG00000077080	0.370327524523035	[]	[]	4	hSpCas9	negative selection	2620237
100655827	100655850	7	-	27260157	DLD1	viability	GCTCCTTCTCAGTCCGCGCTGGG	ACTL6B	ENSG00000077080	0.26852850528292	[]	[]	4	hSpCas9	negative selection	2620846
100655472	100655495	7	+	27260157	DLD1	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-1.25650635981874	[]	[]	-7	hSpCas9	negative selection	2623889
100655444	100655467	7	+	27260157	DLD1	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.204652299905137	[]	[]	3	hSpCas9	negative selection	2641216
100655543	100655566	7	-	27260157	DLD1	viability	GGGCTGCTGGCCGCGGAGGAGGG	ACTL6B	ENSG00000077080	0.484841919757994	[]	[]	8	hSpCas9	negative selection	2641392
100655069	100655092	7	+	27260157	DLD1	viability	GTTTGCTGTAGGTGTGATCCAGG	ACTL6B	ENSG00000077080	-0.0209239490941794	[]	[]	0	hSpCas9	negative selection	2642228
100655461	100655484	7	-	27260157	DLD1	viability	CCAATGCCCTGCACGTGCCTCGG	ACTL6B	ENSG00000077080	0.532097035846237	[]	[]	8	hSpCas9	negative selection	2645134
100655460	100655483	7	-	27260157	DLD1	viability	CAATGCCCTGCACGTGCCTCGGG	ACTL6B	ENSG00000077080	0.416380355690223	[]	[]	7	hSpCas9	negative selection	2646281
100655456	100655479	7	-	27260157	HT1080	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.469786815821891	[]	[]	-7	hSpCas9	negative selection	2650151
100655817	100655840	7	-	27260157	HT1080	viability	AGTCCGCGCTGGGTACGCTGGGG	ACTL6B	ENSG00000077080	-0.248505038283516	[]	[]	0	hSpCas9	negative selection	2654405
100655415	100655438	7	+	27260157	HT1080	viability	CCTTACTCATGCCATTCTTGAGG	ACTL6B	ENSG00000077080	0.223346101654791	[]	[]	2	hSpCas9	negative selection	2656263
100650114	100650137	7	-	27260157	HT1080	viability	GTGGAACACACGGGCCAAGCGGG	ACTL6B	ENSG00000077080	1.86728133295272	[]	[]	9	hSpCas9	negative selection	2661827
100655448	100655471	7	-	27260157	HT1080	viability	CGTGCCTCGGGATGGAGCGGAGG	ACTL6B	ENSG00000077080	-1.14450131087816	[]	[]	-8	hSpCas9	negative selection	2662935
100656346	100656369	7	-	27260157	HT1080	viability	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-1.05589763167652	[]	[]	-8	hSpCas9	negative selection	2686220
100650049	100650072	7	+	27260157	HT1080	viability	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.717256959948085	[]	[]	6	hSpCas9	negative selection	2688342
100655824	100655847	7	+	27260157	HT1080	viability	GTACCCAGCGCGGACTGAGAAGG	ACTL6B	ENSG00000077080	0.423460929370272	[]	[]	4	hSpCas9	negative selection	2691255
100655058	100655081	7	+	27260157	HT1080	viability	AGACTTGACGTGTTTGCTGTAGG	ACTL6B	ENSG00000077080	0.800443329946594	[]	[]	7	hSpCas9	negative selection	2695138
100656344	100656367	7	-	27260157	HT1080	viability	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.82711211131044	[]	[]	-8	hSpCas9	negative selection	2695772
100655818	100655841	7	-	27260157	HT1080	viability	CAGTCCGCGCTGGGTACGCTGGG	ACTL6B	ENSG00000077080	0.435151177198024	[]	[]	4	hSpCas9	negative selection	2696367
100655827	100655850	7	-	27260157	HT1080	viability	GCTCCTTCTCAGTCCGCGCTGGG	ACTL6B	ENSG00000077080	-0.796233050015064	[]	[]	-8	hSpCas9	negative selection	2696976
100655472	100655495	7	+	27260157	HT1080	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.575813586734895	[]	[]	-7	hSpCas9	negative selection	2700019
100655444	100655467	7	+	27260157	HT1080	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.398556392890132	[]	[]	3	hSpCas9	negative selection	2717346
100655543	100655566	7	-	27260157	HT1080	viability	GGGCTGCTGGCCGCGGAGGAGGG	ACTL6B	ENSG00000077080	0.692305352627871	[]	[]	6	hSpCas9	negative selection	2717522
100655069	100655092	7	+	27260157	HT1080	viability	GTTTGCTGTAGGTGTGATCCAGG	ACTL6B	ENSG00000077080	-0.34910654879031	[]	[]	-7	hSpCas9	negative selection	2718358
100655461	100655484	7	-	27260157	HT1080	viability	CCAATGCCCTGCACGTGCCTCGG	ACTL6B	ENSG00000077080	0.743383331795251	[]	[]	6	hSpCas9	negative selection	2721264
100655460	100655483	7	-	27260157	HT1080	viability	CAATGCCCTGCACGTGCCTCGGG	ACTL6B	ENSG00000077080	0.9455406627052	[]	[]	7	hSpCas9	negative selection	2722411
100655456	100655479	7	-	27260157	MKN45	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-1.02528407155034	[]	[]	-8	hSpCas9	negative selection	2726281
100655817	100655840	7	-	27260157	MKN45	viability	AGTCCGCGCTGGGTACGCTGGGG	ACTL6B	ENSG00000077080	-0.658173678077052	[]	[]	-7	hSpCas9	negative selection	2730535
100655415	100655438	7	+	27260157	MKN45	viability	CCTTACTCATGCCATTCTTGAGG	ACTL6B	ENSG00000077080	-0.216430150131761	[]	[]	-1	hSpCas9	negative selection	2732393
100650114	100650137	7	-	27260157	MKN45	viability	GTGGAACACACGGGCCAAGCGGG	ACTL6B	ENSG00000077080	0.76214752882267	[]	[]	7	hSpCas9	negative selection	2737957
100655448	100655471	7	-	27260157	MKN45	viability	CGTGCCTCGGGATGGAGCGGAGG	ACTL6B	ENSG00000077080	-0.474221444693096	[]	[]	-6	hSpCas9	negative selection	2739065
100656346	100656369	7	-	27260157	MKN45	viability	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-1.35902322959215	[]	[]	-8	hSpCas9	negative selection	2762350
100650049	100650072	7	+	27260157	MKN45	viability	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.626782836889319	[]	[]	7	hSpCas9	negative selection	2764472
100655824	100655847	7	+	27260157	MKN45	viability	GTACCCAGCGCGGACTGAGAAGG	ACTL6B	ENSG00000077080	0.285545583602022	[]	[]	5	hSpCas9	negative selection	2767385
100655058	100655081	7	+	27260157	MKN45	viability	AGACTTGACGTGTTTGCTGTAGG	ACTL6B	ENSG00000077080	1.19581150241293	[]	[]	9	hSpCas9	negative selection	2771268
100656344	100656367	7	-	27260157	MKN45	viability	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.91290759786297	[]	[]	-7	hSpCas9	negative selection	2771902
100655818	100655841	7	-	27260157	MKN45	viability	CAGTCCGCGCTGGGTACGCTGGG	ACTL6B	ENSG00000077080	0.372259521122426	[]	[]	6	hSpCas9	negative selection	2772497
100655827	100655850	7	-	27260157	MKN45	viability	GCTCCTTCTCAGTCCGCGCTGGG	ACTL6B	ENSG00000077080	-0.108547900230391	[]	[]	0	hSpCas9	negative selection	2773106
100655472	100655495	7	+	27260157	MKN45	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.580223912517382	[]	[]	-6	hSpCas9	negative selection	2776149
100655444	100655467	7	+	27260157	MKN45	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.414475242209217	[]	[]	-6	hSpCas9	negative selection	2793476
100655543	100655566	7	-	27260157	MKN45	viability	GGGCTGCTGGCCGCGGAGGAGGG	ACTL6B	ENSG00000077080	0.712098157913707	[]	[]	7	hSpCas9	negative selection	2793652
100655069	100655092	7	+	27260157	MKN45	viability	GTTTGCTGTAGGTGTGATCCAGG	ACTL6B	ENSG00000077080	-1.92919622595446	[]	[]	-9	hSpCas9	negative selection	2794488
100655461	100655484	7	-	27260157	MKN45	viability	CCAATGCCCTGCACGTGCCTCGG	ACTL6B	ENSG00000077080	0.801177673694137	[]	[]	7	hSpCas9	negative selection	2797394
100655460	100655483	7	-	27260157	MKN45	viability	CAATGCCCTGCACGTGCCTCGGG	ACTL6B	ENSG00000077080	-1.01022803020683	[]	[]	-8	hSpCas9	negative selection	2798541
100655456	100655479	7	-	27260157	RKO	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-1.58295059911455	[]	[]	-9	hSpCas9	negative selection	2802411
100655817	100655840	7	-	27260157	RKO	viability	AGTCCGCGCTGGGTACGCTGGGG	ACTL6B	ENSG00000077080	-0.493663093773721	[]	[]	-6	hSpCas9	negative selection	2806665
100655415	100655438	7	+	27260157	RKO	viability	CCTTACTCATGCCATTCTTGAGG	ACTL6B	ENSG00000077080	-0.518374612605511	[]	[]	-6	hSpCas9	negative selection	2808523
100650114	100650137	7	-	27260157	RKO	viability	GTGGAACACACGGGCCAAGCGGG	ACTL6B	ENSG00000077080	1.13363811545695	[]	[]	9	hSpCas9	negative selection	2814087
100655448	100655471	7	-	27260157	RKO	viability	CGTGCCTCGGGATGGAGCGGAGG	ACTL6B	ENSG00000077080	-1.33544581650917	[]	[]	-8	hSpCas9	negative selection	2815195
100656346	100656369	7	-	27260157	RKO	viability	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-1.35775340257947	[]	[]	-8	hSpCas9	negative selection	2838480
100650049	100650072	7	+	27260157	RKO	viability	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.199700064101321	[]	[]	1	hSpCas9	negative selection	2840602
100655824	100655847	7	+	27260157	RKO	viability	GTACCCAGCGCGGACTGAGAAGG	ACTL6B	ENSG00000077080	0.107926936077011	[]	[]	0	hSpCas9	negative selection	2843515
100655058	100655081	7	+	27260157	RKO	viability	AGACTTGACGTGTTTGCTGTAGG	ACTL6B	ENSG00000077080	0.435386463326934	[]	[]	2	hSpCas9	negative selection	2847398
100656344	100656367	7	-	27260157	RKO	viability	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.438221069144848	[]	[]	-6	hSpCas9	negative selection	2848032
100655818	100655841	7	-	27260157	RKO	viability	CAGTCCGCGCTGGGTACGCTGGG	ACTL6B	ENSG00000077080	0.35482229936536	[]	[]	2	hSpCas9	negative selection	2848627
100655827	100655850	7	-	27260157	RKO	viability	GCTCCTTCTCAGTCCGCGCTGGG	ACTL6B	ENSG00000077080	-0.46870411898698	[]	[]	-6	hSpCas9	negative selection	2849236
100655472	100655495	7	+	27260157	RKO	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-1.53524065440173	[]	[]	-9	hSpCas9	negative selection	2852279
100655444	100655467	7	+	27260157	RKO	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.0656524278480715	[]	[]	0	hSpCas9	negative selection	2869606
100655543	100655566	7	-	27260157	RKO	viability	GGGCTGCTGGCCGCGGAGGAGGG	ACTL6B	ENSG00000077080	0.942821360391314	[]	[]	8	hSpCas9	negative selection	2869782
100655069	100655092	7	+	27260157	RKO	viability	GTTTGCTGTAGGTGTGATCCAGG	ACTL6B	ENSG00000077080	-0.706136827239355	[]	[]	-7	hSpCas9	negative selection	2870618
100655461	100655484	7	-	27260157	RKO	viability	CCAATGCCCTGCACGTGCCTCGG	ACTL6B	ENSG00000077080	0.365844838614701	[]	[]	2	hSpCas9	negative selection	2873524
100655460	100655483	7	-	27260157	RKO	viability	CAATGCCCTGCACGTGCCTCGGG	ACTL6B	ENSG00000077080	0.314533352871821	[]	[]	1	hSpCas9	negative selection	2874671
100655456	100655479	7	-	27260157	SF268	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.806575031304855	[]	[]	-6	hSpCas9	negative selection	2878541
100655817	100655840	7	-	27260157	SF268	viability	AGTCCGCGCTGGGTACGCTGGGG	ACTL6B	ENSG00000077080	-0.194345597048036	[]	[]	-1	hSpCas9	negative selection	2882795
100655415	100655438	7	+	27260157	SF268	viability	CCTTACTCATGCCATTCTTGAGG	ACTL6B	ENSG00000077080	-0.62016397032294	[]	[]	-5	hSpCas9	negative selection	2884653
100650114	100650137	7	-	27260157	SF268	viability	GTGGAACACACGGGCCAAGCGGG	ACTL6B	ENSG00000077080	1.11104345801365	[]	[]	9	hSpCas9	negative selection	2890217
100655448	100655471	7	-	27260157	SF268	viability	CGTGCCTCGGGATGGAGCGGAGG	ACTL6B	ENSG00000077080	-1.27566282191022	[]	[]	-7	hSpCas9	negative selection	2891325
100656346	100656369	7	-	27260157	SF268	viability	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-1.23146915779422	[]	[]	-7	hSpCas9	negative selection	2914610
100650049	100650072	7	+	27260157	SF268	viability	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	0.301987783592128	[]	[]	4	hSpCas9	negative selection	2916732
100655824	100655847	7	+	27260157	SF268	viability	GTACCCAGCGCGGACTGAGAAGG	ACTL6B	ENSG00000077080	0.205010016356437	[]	[]	3	hSpCas9	negative selection	2919645
100655058	100655081	7	+	27260157	SF268	viability	AGACTTGACGTGTTTGCTGTAGG	ACTL6B	ENSG00000077080	0.731748515098729	[]	[]	8	hSpCas9	negative selection	2923528
100656344	100656367	7	-	27260157	SF268	viability	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.838458680062019	[]	[]	-6	hSpCas9	negative selection	2924162
100655818	100655841	7	-	27260157	SF268	viability	CAGTCCGCGCTGGGTACGCTGGG	ACTL6B	ENSG00000077080	0.0732603473589253	[]	[]	0	hSpCas9	negative selection	2924757
100655827	100655850	7	-	27260157	SF268	viability	GCTCCTTCTCAGTCCGCGCTGGG	ACTL6B	ENSG00000077080	-0.0813364329385057	[]	[]	0	hSpCas9	negative selection	2925366
100655472	100655495	7	+	27260157	SF268	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-1.01997180075156	[]	[]	-7	hSpCas9	negative selection	2928409
100655444	100655467	7	+	27260157	SF268	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.446120915952949	[]	[]	7	hSpCas9	negative selection	2945736
100655543	100655566	7	-	27260157	SF268	viability	GGGCTGCTGGCCGCGGAGGAGGG	ACTL6B	ENSG00000077080	0.452336136937163	[]	[]	7	hSpCas9	negative selection	2945912
100655069	100655092	7	+	27260157	SF268	viability	GTTTGCTGTAGGTGTGATCCAGG	ACTL6B	ENSG00000077080	-0.929439622104355	[]	[]	-6	hSpCas9	negative selection	2946748
100655461	100655484	7	-	27260157	SF268	viability	CCAATGCCCTGCACGTGCCTCGG	ACTL6B	ENSG00000077080	0.694467044059999	[]	[]	8	hSpCas9	negative selection	2949654
100655460	100655483	7	-	27260157	SF268	viability	CAATGCCCTGCACGTGCCTCGGG	ACTL6B	ENSG00000077080	0.109378052493832	[]	[]	0	hSpCas9	negative selection	2950801
100648628	100648651	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATGAAGTCCCCTGCCAGAGGG	ACTL6B	ENSG00000077080	0.11083861294347344	[3,2]	[1,3]	2	hSpCas9	positive selection	2968706
100648808	100648831	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.13647110588425151	[3,3]	[3,2]	3	hSpCas9	positive selection	2968707
100656344	100656367	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.04958492108771666	[4,3]	[3,3]	0	hSpCas9	positive selection	2968708
100655418	100655441	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACTCATGCCATTCTTGAGGGG	ACTL6B	ENSG00000077080	-0.2281291732020123	[3,3]	[2,2]	-3	hSpCas9	positive selection	2968709
100648628	100648651	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATGAAGTCCCCTGCCAGAGGG	ACTL6B	ENSG00000077080	-0.13928792289904393	[3,3]	[3,0]	-2	hSpCas9	positive selection	3036564
100648808	100648831	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.12136617773899253	[3,3]	[3,0]	-2	hSpCas9	positive selection	3036565
100656344	100656367	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.08907537413632925	[4,4]	[4,1]	-1	hSpCas9	positive selection	3036566
100655418	100655441	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACTCATGCCATTCTTGAGGGG	ACTL6B	ENSG00000077080	0.017890771688336922	[3,3]	[3,1]	0	hSpCas9	positive selection	3036567
100656344	100656367		-	24336571	A375	resistance to PLX after 7 days	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	0.07800028210175602	[2,2]	[2,2]	2	hSpCas9	positive selection	3159809
100655828	100655851		-	24336571	A375	resistance to PLX after 7 days	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.212504267606493	[4,6]	[4,5]	-6	hSpCas9	positive selection	3159816
100656344	100656367		-	24336571	A375	resistance to PLX after 14 days	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	0.8767697221655792	[2,1]	[1,1]	7	hSpCas9	positive selection	3217602
100655828	100655851		-	24336571	A375	resistance to PLX after 14 days	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.047867904783989834	[3,8]	[2,2]	0	hSpCas9	positive selection	3217609
100656344	100656367		-	24336571	A375	viability after 7 days	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.7443777734594927	[5]	[2,2]	-8	hSpCas9	negative selection	3275395
100655828	100655851		-	24336571	A375	viability after 7 days	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.7086726931693692	[10]	[4,6]	-7	hSpCas9	negative selection	3275402
100656344	100656367		-	24336571	A375	viability after 14 days	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-1.0658507071004935	[5]	[2,1]	-8	hSpCas9	negative selection	3333188
100655828	100655851		-	24336571	A375	viability after 14 days	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.6172875873862016	[10]	[3,8]	-6	hSpCas9	negative selection	3333195
100656335	100656358	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	3.279597339742237	[32,29]	[2,0]	9	hSpCas9	positive selection	3335407
100655444	100655467	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.6669817515527037	[229,255]	[0,0]	-4	hSpCas9	positive selection	3335408
100655426	100655449	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	-0.1896219170438324	[171,176]	[0,0]	-1	hSpCas9	positive selection	3335409
100655828	100655851	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.18051061439500407	[134,134]	[0,0]	1	hSpCas9	positive selection	3354657
100655868	100655891	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.7495315712471388	[90,90]	[0,0]	3	hSpCas9	positive selection	3354658
100655472	100655495	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	0.38696149186243056	[116,116]	[0,0]	2	hSpCas9	positive selection	3354659
100648627	100648650	7	+	26780180	HT29	viability (Avana library 4 designs)	AGATGAAGTCCCCTGCCAGAGGG	ACTL6B	ENSG00000077080	0.614981469147676	[]	[]	2	hSpCas9	negative selection	3404654
100648808	100648831	7	-	26780180	HT29	viability (Avana library 4 designs)	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	1.70419325286759	[]	[]	6	hSpCas9	negative selection	3404655
100656344	100656367	7	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	2.62503338694388	[]	[]	8	hSpCas9	negative selection	3404656
100655417	100655440	7	+	26780180	HT29	viability (Avana library 4 designs)	TTACTCATGCCATTCTTGAGGGG	ACTL6B	ENSG00000077080	1.26388101804779	[]	[]	5	hSpCas9	negative selection	3404657
100648808	100648831	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	3.84093877863138	[]	[]	6	hSpCas9	negative selection	3476297
100656344	100656367	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	1.7303533548883	[]	[]	2	hSpCas9	negative selection	3476298
100655417	100655440	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTCATGCCATTCTTGAGGGG	ACTL6B	ENSG00000077080	-0.0371787117434073	[]	[]	0	hSpCas9	negative selection	3476299
100648627	100648650	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATGAAGTCCCCTGCCAGAGGG	ACTL6B	ENSG00000077080	0.165027784959188	[]	[]	0	hSpCas9	negative selection	3476300
100655024	100655047	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCCAGTGCTCATGTCCGAGG	ACTL6B	ENSG00000077080	4.93874023579841	[]	[]	8	hSpCas9	negative selection	3476301
100655073	100655096	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTAGGTGTGATCCAGGATGG	ACTL6B	ENSG00000077080	3.83899492403282	[]	[]	6	hSpCas9	negative selection	3476302
100648808	100648831	7	-	26780180	A375	viability (Avana lentiGuide)	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	1.85833954312608	[]	[]	2	hSpCas9	negative selection	3584956
100656344	100656367	7	-	26780180	A375	viability (Avana lentiGuide)	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	8.04390752999241	[]	[]	6	hSpCas9	negative selection	3584957
100655417	100655440	7	+	26780180	A375	viability (Avana lentiGuide)	TTACTCATGCCATTCTTGAGGGG	ACTL6B	ENSG00000077080	0.780523874555628	[]	[]	0	hSpCas9	negative selection	3584958
100648627	100648650	7	+	26780180	A375	viability (Avana lentiGuide)	AGATGAAGTCCCCTGCCAGAGGG	ACTL6B	ENSG00000077080	-1.85159439407531	[]	[]	-3	hSpCas9	negative selection	3584959
100655024	100655047	7	-	26780180	A375	viability (Avana lentiGuide)	GCACCCAGTGCTCATGTCCGAGG	ACTL6B	ENSG00000077080	-0.661460215780076	[]	[]	-1	hSpCas9	negative selection	3584960
100655073	100655096	7	+	26780180	A375	viability (Avana lentiGuide)	GCTGTAGGTGTGATCCAGGATGG	ACTL6B	ENSG00000077080	-3.19418366012071	[]	[]	-5	hSpCas9	negative selection	3584961
100648808	100648831	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.21658531117712188	[4]	[6,4]	6	hSpCas9	positive selection	3693615
100656344	100656367	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	0.02828141150937695	[5]	[5,4]	0	hSpCas9	positive selection	3693616
100655417	100655440	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTCATGCCATTCTTGAGGGG	ACTL6B	ENSG00000077080	0.026397912293942317	[5]	[5,4]	0	hSpCas9	positive selection	3693617
100648627	100648650	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATGAAGTCCCCTGCCAGAGGG	ACTL6B	ENSG00000077080	0.09690312610074947	[4]	[5,4]	2	hSpCas9	positive selection	3693618
100655024	100655047	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCCAGTGCTCATGTCCGAGG	ACTL6B	ENSG00000077080	0.5150982894826535	[4]	[6,5]	9	hSpCas9	positive selection	3693619
100655073	100655096	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTAGGTGTGATCCAGGATGG	ACTL6B	ENSG00000077080	0.18140129797381252	[5]	[6,6]	5	hSpCas9	positive selection	3693620
100648808	100648831	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.03796981437447969	[5]	[3,5]	0	hSpCas9	positive selection	3802222
100656344	100656367	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.3078182556896142	[6]	[3,4]	-4	hSpCas9	positive selection	3802223
100655417	100655440	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTCATGCCATTCTTGAGGGG	ACTL6B	ENSG00000077080	0.08996972338417157	[5]	[5,3]	2	hSpCas9	positive selection	3802224
100648627	100648650	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATGAAGTCCCCTGCCAGAGGG	ACTL6B	ENSG00000077080	0.3064032585629082	[4]	[5,4]	8	hSpCas9	positive selection	3802225
100655024	100655047	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCCAGTGCTCATGTCCGAGG	ACTL6B	ENSG00000077080	-0.5556794924685649	[4]	[1,3]	-6	hSpCas9	positive selection	3802226
100655073	100655096	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTAGGTGTGATCCAGGATGG	ACTL6B	ENSG00000077080	0.3005347800445268	[6]	[7,5]	8	hSpCas9	positive selection	3802227
100656335	100656358	7	-	26780180	A375	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.901588010726831	[]	[]	4	hSpCas9	negative selection	3910829
100655444	100655467	7	+	26780180	A375	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.759243365330059	[]	[]	3	hSpCas9	negative selection	3910830
100655472	100655495	7	+	26780180	A375	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	1.59341639594622	[]	[]	8	hSpCas9	negative selection	3910831
100655828	100655851	7	-	26780180	A375	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	1.17253358571735	[]	[]	6	hSpCas9	negative selection	3910832
100655426	100655449	7	-	26780180	A375	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	1.12376863819036	[]	[]	5	hSpCas9	negative selection	3910833
100655868	100655891	7	-	26780180	A375	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	1.56227259959177	[]	[]	8	hSpCas9	negative selection	3910834
100656335	100656358	7	-	26780180	HT29	viability (GeCKOv2 library)	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	1.07368406810187	[]	[]	5	hSpCas9	negative selection	4018795
100655444	100655467	7	+	26780180	HT29	viability (GeCKOv2 library)	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.651775681402683	[]	[]	2	hSpCas9	negative selection	4018796
100655472	100655495	7	+	26780180	HT29	viability (GeCKOv2 library)	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	1.39205976061688	[]	[]	7	hSpCas9	negative selection	4018797
100655828	100655851	7	-	26780180	HT29	viability (GeCKOv2 library)	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	1.49917922154737	[]	[]	7	hSpCas9	negative selection	4018798
100655426	100655449	7	-	26780180	HT29	viability (GeCKOv2 library)	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.909696765289789	[]	[]	4	hSpCas9	negative selection	4018799
100655868	100655891	7	-	26780180	HT29	viability (GeCKOv2 library)	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.911850504219309	[]	[]	4	hSpCas9	negative selection	4018800
100656344	100656367	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.07171022467485333	[1]	[0,0]	-2	hSpCas9	positive selection	4187780
100655828	100655851	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.2936703755278013	[3]	[1,1]	-6	hSpCas9	positive selection	4187791
100656344	100656367	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.0838017888646776	[1]	[1,0,0,0]	-1	hSpCas9	positive selection	4251802
100655828	100655851	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.7099001001131521	[3]	[0,1,0,3]	4	hSpCas9	positive selection	4251813
100656335	100656358	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.020440429999892096	[1]	[1,0]	0	hSpCas9	positive selection	4254326
100655444	100655467	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.4077703030540994	[3]	[3,4]	8	hSpCas9	positive selection	4254327
100655426	100655449	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	-0.046616582172360664	[2]	[2,1]	-1	hSpCas9	positive selection	4254328
100655828	100655851	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.2327683440843146	[2]	[2,0]	-5	hSpCas9	positive selection	4318609
100655868	100655891	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.42892283123234326	[2]	[1,0]	-7	hSpCas9	positive selection	4318610
100655472	100655495	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	0.23315266582840666	[2]	[2,2]	5	hSpCas9	positive selection	4318611
100655103	100655125	7	+	27760321	OCIAML3	viability	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	-0.25962385609412786	[811,678]	[491,475]	-3	hSpCas9	negative selection	4375881
100655451	100655473	7	-	27760321	OCIAML3	viability	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.6167397981474931	[655,617]	[708,836]	7	hSpCas9	negative selection	4375882
100648612	100648634	7	-	27760321	OCIAML3	viability	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.6289230780510985	[896,824]	[1005,1086]	7	hSpCas9	negative selection	4375883
100648728	100648750	7	-	27760321	OCIAML3	viability	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.43800971426694857	[1047,780]	[864,1084]	5	hSpCas9	negative selection	4375884
100648808	100648830	7	-	27760321	OCIAML3	viability	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.5065160973742864	[516,430]	[556,481]	6	hSpCas9	negative selection	4375885
100655103	100655125	7	+	27760321	OCIAML2	viability	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.10441580169707132	[811,678]	[580,730]	1	hSpCas9	negative selection	4459344
100655451	100655473	7	-	27760321	OCIAML2	viability	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.3955595063464654	[655,617]	[573,815]	5	hSpCas9	negative selection	4459345
100648612	100648634	7	-	27760321	OCIAML2	viability	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.26560463622329544	[896,824]	[705,1009]	3	hSpCas9	negative selection	4459346
100648728	100648750	7	-	27760321	OCIAML2	viability	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.4320280625405093	[1047,780]	[868,1147]	6	hSpCas9	negative selection	4459347
100648808	100648830	7	-	27760321	OCIAML2	viability	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.21404903916631612	[516,430]	[432,455]	3	hSpCas9	negative selection	4459348
100655103	100655125	7	+	27760321	MV411	viability	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	-0.6822128438766887	[811,678]	[248,389]	-5	hSpCas9	negative selection	4542807
100655451	100655473	7	-	27760321	MV411	viability	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.6064665588270646	[655,617]	[566,750]	4	hSpCas9	negative selection	4542808
100648612	100648634	7	-	27760321	MV411	viability	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	1.4174840435781304	[896,824]	[1612,1373]	8	hSpCas9	negative selection	4542809
100648728	100648750	7	-	27760321	MV411	viability	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	1.3478177632894428	[1047,780]	[1588,1422]	8	hSpCas9	negative selection	4542810
100648808	100648830	7	-	27760321	MV411	viability	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	1.30017335207981	[516,430]	[854,634]	8	hSpCas9	negative selection	4542811
100655103	100655125	7	+	27760321	HL60	viability	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.14909330926529207	[811,678]	[806,529]	1	hSpCas9	negative selection	4626270
100655451	100655473	7	-	27760321	HL60	viability	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.08279252015665783	[655,617]	[333,658]	-1	hSpCas9	negative selection	4626271
100648612	100648634	7	-	27760321	HL60	viability	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	-0.06021285139129129	[896,824]	[590,762]	0	hSpCas9	negative selection	4626272
100648728	100648750	7	-	27760321	HL60	viability	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.3527663558398684	[1047,780]	[1000,886]	4	hSpCas9	negative selection	4626273
100648808	100648830	7	-	27760321	HL60	viability	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.2181883374359537	[516,430]	[346,314]	-2	hSpCas9	negative selection	4626274
100655103	100655125	7	+	27760321	HT1080	viability	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	1.2133824654409193	[678,529]	[429,698]	6	hSpCas9	negative selection	4709733
100655451	100655473	7	-	27760321	HT1080	viability	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.040826358683777375	[617,481]	[243,204]	0	hSpCas9	negative selection	4709734
100648612	100648634	7	-	27760321	HT1080	viability	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	-0.7824515322801235	[824,643]	[161,178]	-3	hSpCas9	negative selection	4709735
100648728	100648750	7	-	27760321	HT1080	viability	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	1.1289674934252751	[780,609]	[594,617]	6	hSpCas9	negative selection	4709736
100648808	100648830	7	-	27760321	HT1080	viability	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	1.2843600827759079	[430,336]	[438,299]	7	hSpCas9	negative selection	4709737
100655103	100655125	7	+	27760321	HT29	viability after 7 days	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.3891080172121244	[678,529]	[1347,602,1143]	6	hSpCas9	negative selection	4793196
100655451	100655473	7	-	27760321	HT29	viability after 7 days	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.20917721543324486	[617,481]	[1158,750,596]	3	hSpCas9	negative selection	4793197
100648612	100648634	7	-	27760321	HT29	viability after 7 days	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.1647947092353912	[824,643]	[953,1131,1072]	2	hSpCas9	negative selection	4793198
100648728	100648750	7	-	27760321	HT29	viability after 7 days	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.34751923383830996	[780,609]	[1090,1139,1172]	5	hSpCas9	negative selection	4793199
100648808	100648830	7	-	27760321	HT29	viability after 7 days	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.11531596320786591	[430,336]	[481,443,665]	1	hSpCas9	negative selection	4793200
100655103	100655125	7	+	27760321	HT29	viability after 25 days	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.3793487120945602	[678,529]	[837,791,1087]	4	hSpCas9	negative selection	4876659
100655451	100655473	7	-	27760321	HT29	viability after 25 days	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.39051242107177875	[617,481]	[783,933,746]	4	hSpCas9	negative selection	4876660
100648612	100648634	7	-	27760321	HT29	viability after 25 days	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.2931399930203302	[824,643]	[976,1204,890]	3	hSpCas9	negative selection	4876661
100648728	100648750	7	-	27760321	HT29	viability after 25 days	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.4766500153993438	[780,609]	[1156,1009,1150]	5	hSpCas9	negative selection	4876662
100648808	100648830	7	-	27760321	HT29	viability after 25 days	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.2857974342060985	[430,336]	[542,532,526]	3	hSpCas9	negative selection	4876663
100655103	100655125	7	+	27760321	HT29	viability after 22 days	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.3144078649756423	[678,529]	[1064,738,796]	3	hSpCas9	negative selection	4960122
100655451	100655473	7	-	27760321	HT29	viability after 22 days	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.08058481697832354	[617,481]	[596,747,673]	0	hSpCas9	negative selection	4960123
100648612	100648634	7	-	27760321	HT29	viability after 22 days	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.05960340387565166	[824,643]	[990,872,786]	0	hSpCas9	negative selection	4960124
100648728	100648750	7	-	27760321	HT29	viability after 22 days	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.5594210124178252	[780,609]	[1152,1074,1328]	6	hSpCas9	negative selection	4960125
100648808	100648830	7	-	27760321	HT29	viability after 22 days	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.21654013887088544	[430,336]	[413,447,689]	2	hSpCas9	negative selection	4960126
100655103	100655125	7	+	27760321	HT29	viability after 19 days	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.837971916229757	[678,529]	[1492,694,1533]	8	hSpCas9	negative selection	5043585
100655451	100655473	7	-	27760321	HT29	viability after 19 days	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.47924621412388335	[617,481]	[1064,959,633]	5	hSpCas9	negative selection	5043586
100648612	100648634	7	-	27760321	HT29	viability after 19 days	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.38725691790355765	[824,643]	[1188,1022,1092]	4	hSpCas9	negative selection	5043587
100648728	100648750	7	-	27760321	HT29	viability after 19 days	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.4869270418876035	[780,609]	[1749,835,834]	5	hSpCas9	negative selection	5043588
100648808	100648830	7	-	27760321	HT29	viability after 19 days	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.11024667630530502	[430,336]	[421,445,355]	-1	hSpCas9	negative selection	5043589
100655103	100655125	7	+	27760321	HT29	viability after 16 days	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.8376108334252514	[678,529]	[1292,1465,867]	8	hSpCas9	negative selection	5127048
100655451	100655473	7	-	27760321	HT29	viability after 16 days	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.3597851041122997	[617,481]	[944,457,988]	4	hSpCas9	negative selection	5127049
100648612	100648634	7	-	27760321	HT29	viability after 16 days	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.10960709073003438	[824,643]	[1351,569,789]	1	hSpCas9	negative selection	5127050
100648728	100648750	7	-	27760321	HT29	viability after 16 days	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.5733752456697938	[780,609]	[1241,1099,1140]	6	hSpCas9	negative selection	5127051
100648808	100648830	7	-	27760321	HT29	viability after 16 days	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.04134776092479955	[430,336]	[367,334,546]	0	hSpCas9	negative selection	5127052
100655103	100655125	7	+	27760321	HT29	viability after 13 days	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.4369438560149108	[678,529]	[885,1045,917]	5	hSpCas9	negative selection	5210511
100655451	100655473	7	-	27760321	HT29	viability after 13 days	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.17326890579240606	[617,481]	[606,891,662]	2	hSpCas9	negative selection	5210512
100648612	100648634	7	-	27760321	HT29	viability after 13 days	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.22514636496452511	[824,643]	[1255,900,839]	3	hSpCas9	negative selection	5210513
100648728	100648750	7	-	27760321	HT29	viability after 13 days	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.5173150073605959	[780,609]	[1367,1060,1041]	6	hSpCas9	negative selection	5210514
100648808	100648830	7	-	27760321	HT29	viability after 13 days	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.2480425435346608	[430,336]	[728,451,412]	3	hSpCas9	negative selection	5210515
100655103	100655125	7	+	27760321	HT29	viability after 10 days	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.2474639558918058	[678,529]	[949,1055,690]	3	hSpCas9	negative selection	5293974
100655451	100655473	7	-	27760321	HT29	viability after 10 days	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.3677702440030387	[617,481]	[1014,907,738]	5	hSpCas9	negative selection	5293975
100648612	100648634	7	-	27760321	HT29	viability after 10 days	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.21860029224140987	[824,643]	[836,1206,1158]	3	hSpCas9	negative selection	5293976
100648728	100648750	7	-	27760321	HT29	viability after 10 days	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.3515971835535949	[780,609]	[1024,1224,1077]	5	hSpCas9	negative selection	5293977
100648808	100648830	7	-	27760321	HT29	viability after 10 days	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.5539859049188662	[430,336]	[719,760,633]	7	hSpCas9	negative selection	5293978
100655103	100655125	7	+	27760321	MOLM13	viability	GCACTCCCAGTCCTCGACTGGG	ACTL6B	ENSG00000077080	0.7347520822821765	[811,678]	[392,955]	5	hSpCas9	negative selection	5377437
100655451	100655473	7	-	27760321	MOLM13	viability	CACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	1.1448039437819089	[655,617]	[736,844]	7	hSpCas9	negative selection	5377438
100648612	100648634	7	-	27760321	MOLM13	viability	TTCATCTCCATGCAGTGCCGGG	ACTL6B	ENSG00000077080	0.5147380313730531	[896,824]	[371,967]	3	hSpCas9	negative selection	5377439
100648728	100648750	7	-	27760321	MOLM13	viability	ACGGCTACGTTCTGCAGCAAGG	ACTL6B	ENSG00000077080	0.6899551015373293	[1047,780]	[1374,356]	5	hSpCas9	negative selection	5377440
100648808	100648830	7	-	27760321	MOLM13	viability	TGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.341590746829621	[516,430]	[263,399]	2	hSpCas9	negative selection	5377441
100656344	100656367	7	-	27661255	K562	viability	GCAGCGGGCACTATGAGCGGGGG	ACTL6B	ENSG00000077080	-0.062433818006275954	[1234,931]	[913,763]	-2	dCas9-KRAB	negative selection	5460737
100656335	100656358	7	-	27260156	BXPC3	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.208971878587354	[175]	[138,179,138,180]	-5	hSpCas9	negative selection	5526786
100655444	100655467	7	+	27260156	BXPC3	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.08284331871261985	[859]	[876,744,753,1038]	-2	hSpCas9	negative selection	5526787
100655426	100655449	7	-	27260156	BXPC3	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.2849087058066523	[431]	[410,551,645,612]	6	hSpCas9	negative selection	5526788
100655828	100655851	7	-	27260156	BXPC3	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.20686663374252945	[291]	[292,387,335,399]	4	hSpCas9	negative selection	5591069
100655868	100655891	7	-	27260156	BXPC3	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.1314123916612574	[306]	[280,320,293,270]	-3	hSpCas9	negative selection	5591070
100655472	100655495	7	+	27260156	BXPC3	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.5459302495580376	[369]	[271,205,291,294]	-8	hSpCas9	negative selection	5591071
100656335	100656358	7	-	27260156	A673	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.010917239528119627	[175]	[181,224,216,223]	0	hSpCas9	negative selection	5648037
100655444	100655467	7	+	27260156	A673	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.18835212174934735	[859]	[1353,1164,1034,1171]	4	hSpCas9	negative selection	5648038
100655426	100655449	7	-	27260156	A673	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.24831575429984154	[431]	[589,606,650,611]	6	hSpCas9	negative selection	5648039
100655828	100655851	7	-	27260156	A673	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.16082515331578595	[291]	[512,346,370,348]	4	hSpCas9	negative selection	5712320
100655868	100655891	7	-	27260156	A673	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.06103403774444027	[306]	[410,353,254,402]	-1	hSpCas9	negative selection	5712321
100655472	100655495	7	+	27260156	A673	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.22098566862308883	[369]	[320,345,382,472]	-5	hSpCas9	negative selection	5712322
100656335	100656358	7	-	27260156	A375	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.20418243243011647	[175]	[172,242,323,209]	3	hSpCas9	negative selection	5769288
100655444	100655467	7	+	27260156	A375	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.21195208199240445	[859]	[1144,852,668,805]	-3	hSpCas9	negative selection	5769289
100655426	100655449	7	-	27260156	A375	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.31653172481553354	[431]	[644,747,748,411]	4	hSpCas9	negative selection	5769290
100655828	100655851	7	-	27260156	A375	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.2383630431157578	[291]	[359,731,442,148]	3	hSpCas9	negative selection	5833571
100655868	100655891	7	-	27260156	A375	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.13013555329761523	[306]	[301,637,364,306]	1	hSpCas9	negative selection	5833572
100655472	100655495	7	+	27260156	A375	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.65318250786531	[369]	[364,383,145,224]	-7	hSpCas9	negative selection	5833573
100656335	100656358	7	-	27260156	COLO741	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.2292098874158679	[175]	[147,238,184]	-5	hSpCas9	negative selection	5890539
100655444	100655467	7	+	27260156	COLO741	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.0791040070150576	[859]	[1516,940,1058]	1	hSpCas9	negative selection	5890540
100655426	100655449	7	-	27260156	COLO741	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.09234509396213014	[431]	[778,637,378]	2	hSpCas9	negative selection	5890541
100655828	100655851	7	-	27260156	COLO741	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.19120262262268944	[291]	[379,534,362]	4	hSpCas9	negative selection	5954822
100655868	100655891	7	-	27260156	COLO741	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.6299010795446194	[306]	[255,318,189]	-8	hSpCas9	negative selection	5954823
100655472	100655495	7	+	27260156	COLO741	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.5515473895719374	[369]	[422,295,260]	-8	hSpCas9	negative selection	5954824
100656335	100656358	7	-	27260156	CAL120	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.5740208881752502	[175]	[256,239,467]	8	hSpCas9	negative selection	6011790
100655444	100655467	7	+	27260156	CAL120	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.06874858340979417	[859]	[862,1413,1051]	1	hSpCas9	negative selection	6011791
100655426	100655449	7	-	27260156	CAL120	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.33022085074075985	[431]	[893,653,514]	5	hSpCas9	negative selection	6011792
100655828	100655851	7	-	27260156	CAL120	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.07820587856199368	[291]	[432,392,332]	1	hSpCas9	negative selection	6076073
100655868	100655891	7	-	27260156	CAL120	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.4290537955820815	[306]	[563,511,474]	6	hSpCas9	negative selection	6076074
100655472	100655495	7	+	27260156	CAL120	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.6068107687585107	[369]	[156,368,357]	-7	hSpCas9	negative selection	6076075
100656335	100656358	7	-	27260156	CADOES1	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.16883511238950866	[175]	[185,140,143,109]	-3	hSpCas9	negative selection	6133041
100655444	100655467	7	+	27260156	CADOES1	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.13426246548533283	[859]	[821,806,963,919]	2	hSpCas9	negative selection	6133042
100655426	100655449	7	-	27260156	CADOES1	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.5327835140042644	[431]	[641,441,725,511]	8	hSpCas9	negative selection	6133043
100655828	100655851	7	-	27260156	CADOES1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.32790912760314167	[291]	[382,235,458,282]	5	hSpCas9	negative selection	6197324
100655868	100655891	7	-	27260156	CADOES1	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.4472996851765474	[306]	[292,185,158,198]	-7	hSpCas9	negative selection	6197325
100655472	100655495	7	+	27260156	CADOES1	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.5952212138478863	[369]	[271,185,274,175]	-8	hSpCas9	negative selection	6197326
100656335	100656358	7	-	27260156	EWS502	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.3250174958293168	[175]	[172,99,140,181]	-5	hSpCas9	negative selection	6254292
100655444	100655467	7	+	27260156	EWS502	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.3258088228788125	[859]	[710,1351,1061,1505]	6	hSpCas9	negative selection	6254293
100655426	100655449	7	-	27260156	EWS502	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.34261693420553313	[431]	[494,607,592,635]	6	hSpCas9	negative selection	6254294
100655828	100655851	7	-	27260156	EWS502	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.22443863120280194	[291]	[316,324,416,394]	4	hSpCas9	negative selection	6318575
100655868	100655891	7	-	27260156	EWS502	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.20510109513272934	[306]	[232,287,323,288]	-4	hSpCas9	negative selection	6318576
100655472	100655495	7	+	27260156	EWS502	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.43702972214024943	[369]	[214,303,247,405]	-6	hSpCas9	negative selection	6318577
100656335	100656358	7	-	27260156	EW8	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.276285959724631	[175]	[138,159,157,231]	5	hSpCas9	negative selection	6375543
100655444	100655467	7	+	27260156	EW8	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.2972225165043392	[859]	[936,776,775,954]	5	hSpCas9	negative selection	6375544
100655426	100655449	7	-	27260156	EW8	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.2363508001576088	[431]	[431,443,393,383]	4	hSpCas9	negative selection	6375545
100655828	100655851	7	-	27260156	EW8	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.11622527572279184	[291]	[267,263,235,261]	2	hSpCas9	negative selection	6439826
100655868	100655891	7	-	27260156	EW8	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.18942549559976124	[306]	[275,316,255,288]	3	hSpCas9	negative selection	6439827
100655472	100655495	7	+	27260156	EW8	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.4090357579274057	[369]	[201,169,222,304]	-6	hSpCas9	negative selection	6439828
100656335	100656358	7	-	27260156	CORL105	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.2943312762567263	[175]	[241,246,250,269]	5	hSpCas9	negative selection	6496794
100655444	100655467	7	+	27260156	CORL105	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.08208184450459455	[859]	[1023,786,1332,1163]	1	hSpCas9	negative selection	6496795
100655426	100655449	7	-	27260156	CORL105	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.6930703577334261	[431]	[900,629,802,939]	9	hSpCas9	negative selection	6496796
100655828	100655851	7	-	27260156	CORL105	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.04291989808468977	[291]	[399,321,371,319]	0	hSpCas9	negative selection	6561077
100655868	100655891	7	-	27260156	CORL105	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.33588375029203	[306]	[269,215,350,312]	-6	hSpCas9	negative selection	6561078
100655472	100655495	7	+	27260156	CORL105	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.6093816871979969	[369]	[329,162,344,310]	-8	hSpCas9	negative selection	6561079
100656335	100656358	7	-	27260156	HS294T	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.17597289335227395	[175]	[71,88,75,68]	2	hSpCas9	negative selection	6618045
100655444	100655467	7	+	27260156	HS294T	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.11088627630015091	[859]	[218,273,331,436]	-1	hSpCas9	negative selection	6618046
100655426	100655449	7	-	27260156	HS294T	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.2585813316055759	[431]	[191,230,176,197]	3	hSpCas9	negative selection	6618047
100655828	100655851	7	-	27260156	HS294T	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.008762484627281908	[291]	[52,179,98,127]	0	hSpCas9	negative selection	6682328
100655868	100655891	7	-	27260156	HS294T	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.4767591866320813	[306]	[100,84,64,88]	-6	hSpCas9	negative selection	6682329
100655472	100655495	7	+	27260156	HS294T	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.4050814804111053	[369]	[51,37,134,235]	-5	hSpCas9	negative selection	6682330
100656335	100656358	7	-	27260156	HCC44	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.15591385161753224	[175]	[269,243,277,107]	2	hSpCas9	negative selection	6739296
100655444	100655467	7	+	27260156	HCC44	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.0781169814057695	[859]	[1116,674,1342,1074]	1	hSpCas9	negative selection	6739297
100655426	100655449	7	-	27260156	HCC44	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.38051373263680044	[431]	[765,611,528,628]	6	hSpCas9	negative selection	6739298
100655828	100655851	7	-	27260156	HCC44	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.3707857854794486	[291]	[389,493,340,450]	6	hSpCas9	negative selection	6803579
100655868	100655891	7	-	27260156	HCC44	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.0872211057027098	[306]	[231,281,441,364]	-1	hSpCas9	negative selection	6803580
100655472	100655495	7	+	27260156	HCC44	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.331705237301365	[369]	[379,313,301,332]	-5	hSpCas9	negative selection	6803581
100656335	100656358	7	-	27260156	G402	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.8021095241070372	[175]	[242,237,688,302]	8	hSpCas9	negative selection	6860547
100655444	100655467	7	+	27260156	G402	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.4531652789862888	[859]	[1183,1508,928,2055]	5	hSpCas9	negative selection	6860548
100655426	100655449	7	-	27260156	G402	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.3739090638697013	[431]	[1203,461,780,360]	5	hSpCas9	negative selection	6860549
100655828	100655851	7	-	27260156	G402	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.008043552558141709	[291]	[397,292,380,346]	0	hSpCas9	negative selection	6924830
100655868	100655891	7	-	27260156	G402	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.6327955855816363	[306]	[455,1110,399,376]	7	hSpCas9	negative selection	6924831
100655472	100655495	7	+	27260156	G402	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.6637579218233991	[369]	[303,166,532,137]	-7	hSpCas9	negative selection	6924832
100656335	100656358	7	-	27260156	L33	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.3545903706954625	[175]	[268,89,95,256]	7	hSpCas9	negative selection	6981798
100655444	100655467	7	+	27260156	L33	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.09222233933159052	[859]	[911,401,533,923]	2	hSpCas9	negative selection	6981799
100655426	100655449	7	-	27260156	L33	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.6027092145080286	[431]	[626,259,443,656]	9	hSpCas9	negative selection	6981800
100655828	100655851	7	-	27260156	L33	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.11227351369032379	[291]	[264,107,192,426]	2	hSpCas9	negative selection	7046081
100655868	100655891	7	-	27260156	L33	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.1304969438459228	[306]	[260,101,194,301]	-3	hSpCas9	negative selection	7046082
100655472	100655495	7	+	27260156	L33	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.3150300928633207	[369]	[249,141,175,313]	-6	hSpCas9	negative selection	7046083
100656335	100656358	7	-	27260156	K562	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.014655106935343998	[175]	[50,156,258,154]	0	hSpCas9	negative selection	7103049
100655444	100655467	7	+	27260156	K562	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.1371811726080555	[859]	[547,758,778,679]	-2	hSpCas9	negative selection	7103050
100655426	100655449	7	-	27260156	K562	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.4689998929471812	[431]	[360,595,453,680]	6	hSpCas9	negative selection	7103051
100655828	100655851	7	-	27260156	K562	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.34581636916276204	[291]	[212,141,288,171]	-4	hSpCas9	negative selection	7167332
100655868	100655891	7	-	27260156	K562	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.5033895500386398	[306]	[340,355,52,54]	-6	hSpCas9	negative selection	7167333
100655472	100655495	7	+	27260156	K562	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.4907554254662602	[369]	[138,267,232,281]	-5	hSpCas9	negative selection	7167334
100656335	100656358	7	-	27260156	HT29	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.38797296534743375	[175]	[149,118,188,186]	-6	hSpCas9	negative selection	7224300
100655444	100655467	7	+	27260156	HT29	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.07345272682931503	[859]	[1279,1139,1262,767]	1	hSpCas9	negative selection	7224301
100655426	100655449	7	-	27260156	HT29	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.4234009424373586	[431]	[682,804,752,591]	7	hSpCas9	negative selection	7224302
100655828	100655851	7	-	27260156	HT29	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.10343454291701049	[291]	[328,271,390,322]	-2	hSpCas9	negative selection	7288583
100655868	100655891	7	-	27260156	HT29	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.006417968939777752	[306]	[307,348,588,257]	0	hSpCas9	negative selection	7288584
100655472	100655495	7	+	27260156	HT29	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.22482195032428737	[369]	[466,401,420,268]	-4	hSpCas9	negative selection	7288585
100656335	100656358	7	-	27260156	MHHES1	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.32009456606317244	[175]	[257,425,205,138]	6	hSpCas9	negative selection	7345551
100655444	100655467	7	+	27260156	MHHES1	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.10597897500535847	[859]	[844,1473,1041,849]	2	hSpCas9	negative selection	7345552
100655426	100655449	7	-	27260156	MHHES1	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.5021286668969083	[431]	[535,835,702,666]	8	hSpCas9	negative selection	7345553
100655828	100655851	7	-	27260156	MHHES1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.2551665595659735	[291]	[328,575,384,302]	5	hSpCas9	negative selection	7409834
100655868	100655891	7	-	27260156	MHHES1	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.17079564324390084	[306]	[389,346,352,440]	3	hSpCas9	negative selection	7409835
100655472	100655495	7	+	27260156	MHHES1	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.20619180023008415	[369]	[401,382,275,377]	-4	hSpCas9	negative selection	7409836
100656335	100656358	7	-	27260156	MEWO	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.14550612025462684	[175]	[230,145,178]	3	hSpCas9	negative selection	7466802
100655444	100655467	7	+	27260156	MEWO	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.057835599959337736	[859]	[818,777,911]	1	hSpCas9	negative selection	7466803
100655426	100655449	7	-	27260156	MEWO	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.38074479665972627	[431]	[648,391,561]	7	hSpCas9	negative selection	7466804
100655828	100655851	7	-	27260156	MEWO	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.17533770487262879	[291]	[373,325,237]	4	hSpCas9	negative selection	7531085
100655868	100655891	7	-	27260156	MEWO	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.04453012590354766	[306]	[331,230,282]	-1	hSpCas9	negative selection	7531086
100655472	100655495	7	+	27260156	MEWO	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.3375851835062205	[369]	[274,264,281]	-6	hSpCas9	negative selection	7531087
100656335	100656358	7	-	27260156	LNCAPCLONEFGC	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.18978923520603264	[175]	[182,116,87,163]	-3	hSpCas9	negative selection	7588053
100655444	100655467	7	+	27260156	LNCAPCLONEFGC	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.09498923973933926	[859]	[776,832,739,964]	1	hSpCas9	negative selection	7588054
100655426	100655449	7	-	27260156	LNCAPCLONEFGC	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.30402330033257907	[431]	[415,522,564,438]	5	hSpCas9	negative selection	7588055
100655828	100655851	7	-	27260156	LNCAPCLONEFGC	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.3714898885900738	[291]	[370,314,309,368]	6	hSpCas9	negative selection	7652336
100655868	100655891	7	-	27260156	LNCAPCLONEFGC	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.15811546692444733	[306]	[294,216,282,207]	-3	hSpCas9	negative selection	7652337
100655472	100655495	7	+	27260156	LNCAPCLONEFGC	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.3718117976470115	[369]	[188,243,263,341]	-5	hSpCas9	negative selection	7652338
100656335	100656358	7	-	27260156	PANC0327	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.32257416573274345	[175]	[173,144,318,148]	5	hSpCas9	negative selection	7709304
100655444	100655467	7	+	27260156	PANC0327	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.1166824416376393	[859]	[822,624,641,747]	-2	hSpCas9	negative selection	7709305
100655426	100655449	7	-	27260156	PANC0327	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	-0.4641640862087902	[431]	[406,286,222,204]	-6	hSpCas9	negative selection	7709306
100655828	100655851	7	-	27260156	PANC0327	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.047935102717923894	[291]	[400,254,192,235]	0	hSpCas9	negative selection	7773587
100655868	100655891	7	-	27260156	PANC0327	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.8306876551819211	[306]	[459,722,339,383]	9	hSpCas9	negative selection	7773588
100655472	100655495	7	+	27260156	PANC0327	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	0.2863272522714797	[369]	[147,464,370,589]	4	hSpCas9	negative selection	7773589
100656335	100656358	7	-	27260156	NCIH2009	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.6260474483107339	[175]	[308,485,326]	8	hSpCas9	negative selection	7830555
100655444	100655467	7	+	27260156	NCIH2009	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.1243905538898451	[859]	[1906,1148,991]	1	hSpCas9	negative selection	7830556
100655426	100655449	7	-	27260156	NCIH2009	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.8635876709705442	[431]	[1271,942,1114]	9	hSpCas9	negative selection	7830557
100655828	100655851	7	-	27260156	NCIH2009	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.0811951637018199	[291]	[468,344,488]	1	hSpCas9	negative selection	7894838
100655868	100655891	7	-	27260156	NCIH2009	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.1598136962654868	[306]	[386,372,391]	-2	hSpCas9	negative selection	7894839
100655472	100655495	7	+	27260156	NCIH2009	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-1.2351038312707614	[369]	[384,171,134]	-8	hSpCas9	negative selection	7894840
100656335	100656358	7	-	27260156	NCIH1373	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.17944270533392492	[175]	[116,161,295,27]	-2	hSpCas9	negative selection	7951806
100655444	100655467	7	+	27260156	NCIH1373	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.4740549151228257	[859]	[708,532,762,207]	-5	hSpCas9	negative selection	7951807
100655426	100655449	7	-	27260156	NCIH1373	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.6033113440538248	[431]	[840,483,1072,148]	6	hSpCas9	negative selection	7951808
100655828	100655851	7	-	27260156	NCIH1373	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.11193254852735834	[291]	[568,259,257,97]	1	hSpCas9	negative selection	8016089
100655868	100655891	7	-	27260156	NCIH1373	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.7005757870297034	[306]	[375,186,173,34]	-6	hSpCas9	negative selection	8016090
100655472	100655495	7	+	27260156	NCIH1373	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-1.8429604584690784	[369]	[167,58,46,54]	-9	hSpCas9	negative selection	8016091
100656335	100656358	7	-	27260156	PATU8902	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-1.4008704846788276	[175]	[119,175,30,54]	-8	hSpCas9	negative selection	8073057
100655444	100655467	7	+	27260156	PATU8902	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.1266631707429825	[859]	[1234,688,851,1740]	-1	hSpCas9	negative selection	8073058
100655426	100655449	7	-	27260156	PATU8902	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	-0.07687960895943387	[431]	[660,414,561,648]	0	hSpCas9	negative selection	8073059
100655828	100655851	7	-	27260156	PATU8902	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.5593249103444999	[291]	[485,517,627,774]	6	hSpCas9	negative selection	8137340
100655868	100655891	7	-	27260156	PATU8902	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.8621742745636194	[306]	[269,282,93,340]	-7	hSpCas9	negative selection	8137341
100655472	100655495	7	+	27260156	PATU8902	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.5168398385116075	[369]	[447,390,192,459]	-5	hSpCas9	negative selection	8137342
100656335	100656358	7	-	27260156	PANC1	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.11939565387233597	[175]	[155,128,201,75]	-2	hSpCas9	negative selection	8194308
100655444	100655467	7	+	27260156	PANC1	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.284065058005633	[859]	[761,1155,994,750]	4	hSpCas9	negative selection	8194309
100655426	100655449	7	-	27260156	PANC1	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.4671082899673816	[431]	[477,704,437,468]	7	hSpCas9	negative selection	8194310
100655828	100655851	7	-	27260156	PANC1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.3546175658938306	[291]	[351,439,272,247]	6	hSpCas9	negative selection	8258591
100655868	100655891	7	-	27260156	PANC1	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.32901705716141627	[306]	[279,206,186,166]	-5	hSpCas9	negative selection	8258592
100655472	100655495	7	+	27260156	PANC1	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.13972855457680095	[369]	[228,451,330,188]	-2	hSpCas9	negative selection	8258593
100656335	100656358	7	-	27260156	PANC0813	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.01804524779316652	[175]	[317,173,172,163]	0	hSpCas9	negative selection	8315559
100655444	100655467	7	+	27260156	PANC0813	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.23783039777360404	[859]	[1143,1171,1201,1237]	4	hSpCas9	negative selection	8315560
100655426	100655449	7	-	27260156	PANC0813	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.9133886056716295	[431]	[1142,732,1090,876]	9	hSpCas9	negative selection	8315561
100655828	100655851	7	-	27260156	PANC0813	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.1497570125748806	[291]	[446,277,222,300]	-2	hSpCas9	negative selection	8379842
100655868	100655891	7	-	27260156	PANC0813	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.06481286885107884	[306]	[418,337,298,329]	-1	hSpCas9	negative selection	8379843
100655472	100655495	7	+	27260156	PANC0813	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.18667648399280418	[369]	[326,372,284,527]	-3	hSpCas9	negative selection	8379844
100656335	100656358	7	-	27260156	RDES	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.009241445293856732	[175]	[130,255,226,206]	0	hSpCas9	negative selection	8436810
100655444	100655467	7	+	27260156	RDES	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.031092129600696627	[859]	[749,952,1204,1203]	0	hSpCas9	negative selection	8436811
100655426	100655449	7	-	27260156	RDES	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.10808555510671687	[431]	[467,469,606,615]	1	hSpCas9	negative selection	8436812
100655828	100655851	7	-	27260156	RDES	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.3829486601644841	[291]	[384,489,467,394]	6	hSpCas9	negative selection	8501093
100655868	100655891	7	-	27260156	RDES	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.24530017168318663	[306]	[266,280,315,331]	-4	hSpCas9	negative selection	8501094
100655472	100655495	7	+	27260156	RDES	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-1.005181881750701	[369]	[130,201,231,311]	-9	hSpCas9	negative selection	8501095
100656335	100656358	7	-	27260156	PC3	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.08579072566504653	[175]	[103,211,370,145]	2	hSpCas9	negative selection	8558061
100655444	100655467	7	+	27260156	PC3	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.03238944717468528	[859]	[598,607,1507,1093]	0	hSpCas9	negative selection	8558062
100655426	100655449	7	-	27260156	PC3	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.39487156514385346	[431]	[420,559,988,453]	8	hSpCas9	negative selection	8558063
100655828	100655851	7	-	27260156	PC3	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.1256527477687679	[291]	[216,426,317,310]	3	hSpCas9	negative selection	8622344
100655868	100655891	7	-	27260156	PC3	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.010107098561652816	[306]	[146,156,758,406]	0	hSpCas9	negative selection	8622345
100655472	100655495	7	+	27260156	PC3	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.255590137254398	[369]	[168,188,661,399]	-5	hSpCas9	negative selection	8622346
100656335	100656358	7	-	27260156	PATU8988T	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.40773025621062375	[175]	[94,144,97,180]	-6	hSpCas9	negative selection	8679312
100655444	100655467	7	+	27260156	PATU8988T	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.2094848056613754	[859]	[861,1305,823,878]	3	hSpCas9	negative selection	8679313
100655426	100655449	7	-	27260156	PATU8988T	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.49223227003557235	[431]	[427,598,661,665]	8	hSpCas9	negative selection	8679314
100655828	100655851	7	-	27260156	PATU8988T	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.0039965335859663	[291]	[302,170,295,356]	0	hSpCas9	negative selection	8743595
100655868	100655891	7	-	27260156	PATU8988T	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.49824686529332807	[306]	[217,161,59,413]	-7	hSpCas9	negative selection	8743596
100655472	100655495	7	+	27260156	PATU8988T	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.5832670246285698	[369]	[221,136,291,297]	-7	hSpCas9	negative selection	8743597
100656335	100656358	7	-	27260156	T47D	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.050045819232060085	[175]	[254,117,260,222]	1	hSpCas9	negative selection	8800563
100655444	100655467	7	+	27260156	T47D	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.03473712178052535	[859]	[983,1085,918,1114]	0	hSpCas9	negative selection	8800564
100655426	100655449	7	-	27260156	T47D	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.27726046245431185	[431]	[595,693,497,646]	6	hSpCas9	negative selection	8800565
100655828	100655851	7	-	27260156	T47D	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.32492763095288546	[291]	[360,381,477,487]	7	hSpCas9	negative selection	8864846
100655868	100655891	7	-	27260156	T47D	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.09639059870552824	[306]	[326,327,375,305]	-2	hSpCas9	negative selection	8864847
100655472	100655495	7	+	27260156	T47D	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.29401228767006476	[369]	[341,282,409,376]	-6	hSpCas9	negative selection	8864848
100656335	100656358	7	-	27260156	SU8686	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.5129942610992404	[175]	[294,216,178,309]	8	hSpCas9	negative selection	8921814
100655444	100655467	7	+	27260156	SU8686	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.14186019377839054	[859]	[847,776,1154,1027]	2	hSpCas9	negative selection	8921815
100655426	100655449	7	-	27260156	SU8686	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.7145381675056557	[431]	[629,661,735,809]	9	hSpCas9	negative selection	8921816
100655828	100655851	7	-	27260156	SU8686	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.26563572336296976	[291]	[283,308,321,512]	4	hSpCas9	negative selection	8986097
100655868	100655891	7	-	27260156	SU8686	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.3079429980967383	[306]	[137,245,350,264]	-5	hSpCas9	negative selection	8986098
100655472	100655495	7	+	27260156	SU8686	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.008453204344958554	[369]	[303,190,540,471]	0	hSpCas9	negative selection	8986099
100656335	100656358	7	-	27260156	SKES1	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.3814921058023675	[175]	[341,180,221,182]	7	hSpCas9	negative selection	9043065
100655444	100655467	7	+	27260156	SKES1	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.2008244479212986	[859]	[1186,1204,814,804]	4	hSpCas9	negative selection	9043066
100655426	100655449	7	-	27260156	SKES1	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.2046786935175677	[431]	[388,590,567,435]	4	hSpCas9	negative selection	9043067
100655828	100655851	7	-	27260156	SKES1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.2855325445310169	[291]	[339,550,297,260]	6	hSpCas9	negative selection	9107348
100655868	100655891	7	-	27260156	SKES1	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.0602827392485783	[306]	[363,346,292,283]	1	hSpCas9	negative selection	9107349
100655472	100655495	7	+	27260156	SKES1	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.3888118611454026	[369]	[229,300,302,284]	-7	hSpCas9	negative selection	9107350
100656335	100656358	7	-	27260156	TOV112D	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.31438113617406094	[175]	[225,140,244,244]	6	hSpCas9	negative selection	9164316
100655444	100655467	7	+	27260156	TOV112D	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	-0.02007657492742443	[859]	[940,1017,654,831]	0	hSpCas9	negative selection	9164317
100655426	100655449	7	-	27260156	TOV112D	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.08964464151507504	[431]	[544,702,282,378]	1	hSpCas9	negative selection	9164318
100655828	100655851	7	-	27260156	TOV112D	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.06393954387304157	[291]	[233,385,308,306]	1	hSpCas9	negative selection	9228599
100655868	100655891	7	-	27260156	TOV112D	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.21483723268976274	[306]	[290,356,201,234]	-4	hSpCas9	negative selection	9228600
100655472	100655495	7	+	27260156	TOV112D	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.3143765250427632	[369]	[339,329,235,296]	-6	hSpCas9	negative selection	9228601
100656335	100656358	7	-	27260156	TC71	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	0.014073447158309715	[175]	[186,220,173,179]	0	hSpCas9	negative selection	9285567
100655444	100655467	7	+	27260156	TC71	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.3511187123571273	[859]	[1042,1119,1145,1412]	8	hSpCas9	negative selection	9285568
100655426	100655449	7	-	27260156	TC71	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.3210644996044706	[431]	[509,631,603,567]	7	hSpCas9	negative selection	9285569
100655828	100655851	7	-	27260156	TC71	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.1460318206420934	[291]	[366,296,323,400]	3	hSpCas9	negative selection	9349850
100655868	100655891	7	-	27260156	TC71	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	0.15328778149987782	[306]	[362,312,381,407]	4	hSpCas9	negative selection	9349851
100655472	100655495	7	+	27260156	TC71	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.15990604949726456	[369]	[338,280,317,491]	-4	hSpCas9	negative selection	9349852
100656335	100656358	7	-	27260156	TC32	viability	ACTATGAGCGGGGGCGTCTACGG	ACTL6B	ENSG00000077080	-0.2872331348419459	[175]	[147,107,140,146]	-5	hSpCas9	negative selection	9406818
100655444	100655467	7	+	27260156	TC32	viability	ATGACCTCCGCTCCATCCCGAGG	ACTL6B	ENSG00000077080	0.04495030394228283	[859]	[684,821,925,890]	0	hSpCas9	negative selection	9406819
100655426	100655449	7	-	27260156	TC32	viability	GTCATGTCGCCCCTCAAGAATGG	ACTL6B	ENSG00000077080	0.3487394128144339	[431]	[559,385,708,454]	6	hSpCas9	negative selection	9406820
100655828	100655851	7	-	27260156	TC32	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.45560261672810465	[291]	[363,367,375,376]	7	hSpCas9	negative selection	9471101
100655868	100655891	7	-	27260156	TC32	viability	TCCCCGCACAGATGAGGTGGGGG	ACTL6B	ENSG00000077080	-0.19871271843566718	[306]	[167,151,406,345]	-4	hSpCas9	negative selection	9471102
100655472	100655495	7	+	27260156	TC32	viability	GCAGGGCATTGGTGTCGATGTGG	ACTL6B	ENSG00000077080	-0.34905634673367586	[369]	[228,122,473,353]	-6	hSpCas9	negative selection	9471103
100648808	100648831	7	-	27869803	HPAFII	viability after 27 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.8192232762852851	[146]	[185,94,NaN]	6	hSpCas9	negative selection	9597255
100650049	100650072	7	+	27869803	HPAFII	viability after 27 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.2683665493304066	[266]	[193,51,NaN]	-2	hSpCas9	negative selection	9597256
100655101	100655124	7	+	27869803	HPAFII	viability after 27 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.18710498702913947	[137]	[42,80,NaN]	-1	hSpCas9	negative selection	9597257
100655451	100655474	7	-	27869803	HPAFII	viability after 27 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.20321489698913073	[189]	[180,59,NaN]	1	hSpCas9	negative selection	9597258
100655819	100655842	7	-	27869803	HPAFII	viability after 27 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.04653868253607618	[439]	[197,272,NaN]	0	hSpCas9	negative selection	9597259
100656346	100656369	7	-	27869803	HPAFII	viability after 27 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-5.451797912695558	[332]	[3,3,NaN]	-9	hSpCas9	negative selection	9597260
100648808	100648831	7	-	27869803	HPAFII	viability after 15 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.449776855696264	[146]	[364,122,NaN]	5	hSpCas9	negative selection	9679704
100650049	100650072	7	+	27869803	HPAFII	viability after 15 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.08232366895633847	[266]	[484,137,NaN]	-1	hSpCas9	negative selection	9679705
100655101	100655124	7	+	27869803	HPAFII	viability after 15 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.7601519807572499	[137]	[110,72,NaN]	-7	hSpCas9	negative selection	9679706
100655451	100655474	7	-	27869803	HPAFII	viability after 15 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.2112300733292103	[189]	[213,152,NaN]	-2	hSpCas9	negative selection	9679707
100655819	100655842	7	-	27869803	HPAFII	viability after 15 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.31278561200382726	[439]	[595,581,NaN]	3	hSpCas9	negative selection	9679708
100656346	100656369	7	-	27869803	HPAFII	viability after 15 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-1.8113771903733715	[332]	[117,91,NaN]	-9	hSpCas9	negative selection	9679709
100648808	100648831	7	-	27869803	ASPC1	viability after 36 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	-0.23309628683285272	[577]	[93,224,181]	-2	hSpCas9	negative selection	9762153
100650049	100650072	7	+	27869803	ASPC1	viability after 36 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.19567607493898448	[551]	[205,103,190]	-2	hSpCas9	negative selection	9762154
100655101	100655124	7	+	27869803	ASPC1	viability after 36 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.758774780100512	[428]	[80,81,97]	-6	hSpCas9	negative selection	9762155
100655451	100655474	7	-	27869803	ASPC1	viability after 36 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.11613357134681629	[513]	[278,147,169]	1	hSpCas9	negative selection	9762156
100655819	100655842	7	-	27869803	ASPC1	viability after 36 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.306852186850999	[1162]	[465,916,192]	3	hSpCas9	negative selection	9762157
100656346	100656369	7	-	27869803	ASPC1	viability after 36 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	0.398338745522222	[864]	[455,358,383]	4	hSpCas9	negative selection	9762158
100648808	100648831	7	-	27869803	PATU8988S	viability after 35 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.14051696726650015	[588]	[255,266,NaN]	1	hSpCas9	negative selection	9844602
100650049	100650072	7	+	27869803	PATU8988S	viability after 35 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.3453615532011385	[592]	[181,193,NaN]	-4	hSpCas9	negative selection	9844603
100655101	100655124	7	+	27869803	PATU8988S	viability after 35 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.36467499556212024	[293]	[74,108,NaN]	-4	hSpCas9	negative selection	9844604
100655451	100655474	7	-	27869803	PATU8988S	viability after 35 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.19970973361961025	[382]	[244,108,NaN]	2	hSpCas9	negative selection	9844605
100655819	100655842	7	-	27869803	PATU8988S	viability after 35 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.49166219344205375	[907]	[598,428,NaN]	5	hSpCas9	negative selection	9844606
100656346	100656369	7	-	27869803	PATU8988S	viability after 35 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.8094131939269552	[682]	[140,172,NaN]	-7	hSpCas9	negative selection	9844607
100648808	100648831	7	-	27869803	PATU8988S	viability after 31 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.251931262266469	[588]	[236,333,NaN]	3	hSpCas9	negative selection	9927051
100650049	100650072	7	+	27869803	PATU8988S	viability after 31 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.07955661389527777	[592]	[265,169,NaN]	-1	hSpCas9	negative selection	9927052
100655101	100655124	7	+	27869803	PATU8988S	viability after 31 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.2646171505666981	[293]	[24,189,NaN]	-3	hSpCas9	negative selection	9927053
100655451	100655474	7	-	27869803	PATU8988S	viability after 31 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.28435028774100235	[382]	[120,130,NaN]	-3	hSpCas9	negative selection	9927054
100655819	100655842	7	-	27869803	PATU8988S	viability after 31 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.4219619827543717	[907]	[426,558,NaN]	5	hSpCas9	negative selection	9927055
100656346	100656369	7	-	27869803	PATU8988S	viability after 31 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-0.5053006553947792	[682]	[135,262,NaN]	-5	hSpCas9	negative selection	9927056
100648808	100648831	7	-	27869803	HPAFII	viability after 35 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.7244206569126966	[146]	[153,87,NaN]	5	hSpCas9	negative selection	10009500
100650049	100650072	7	+	27869803	HPAFII	viability after 35 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-1.2114141157394145	[266]	[95,15,NaN]	-6	hSpCas9	negative selection	10009501
100655101	100655124	7	+	27869803	HPAFII	viability after 35 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.2571925950908438	[137]	[25,94,NaN]	-2	hSpCas9	negative selection	10009502
100655451	100655474	7	-	27869803	HPAFII	viability after 35 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	0.5988903961470734	[189]	[211,70,NaN]	4	hSpCas9	negative selection	10009503
100655819	100655842	7	-	27869803	HPAFII	viability after 35 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.08003360340863441	[439]	[202,271,NaN]	0	hSpCas9	negative selection	10009504
100656346	100656369	7	-	27869803	HPAFII	viability after 35 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-3.8333889288812606	[332]	[16,5,NaN]	-9	hSpCas9	negative selection	10009505
100648808	100648831	7	-	27869803	HPAFII	viability after 31 days	ATGCCAGCTTTGCAAACGGGCGG	ACTL6B	ENSG00000077080	0.7732502072376869	[146]	[140,140,NaN]	5	hSpCas9	negative selection	10091949
100650049	100650072	7	+	27869803	HPAFII	viability after 31 days	AGCCGTCTTGCATAAGAAGAAGG	ACTL6B	ENSG00000077080	-0.36490876554438256	[266]	[168,58,NaN]	-2	hSpCas9	negative selection	10091950
100655101	100655124	7	+	27869803	HPAFII	viability after 31 days	AAGCACTCCCAGTCCTCGACTGG	ACTL6B	ENSG00000077080	-0.04688426942979429	[137]	[51,99,NaN]	0	hSpCas9	negative selection	10091951
100655451	100655474	7	-	27869803	HPAFII	viability after 31 days	GCACGTGCCTCGGGATGGAGCGG	ACTL6B	ENSG00000077080	-0.16586968689450055	[189]	[151,32,NaN]	-1	hSpCas9	negative selection	10091952
100655819	100655842	7	-	27869803	HPAFII	viability after 31 days	TCAGTCCGCGCTGGGTACGCTGG	ACTL6B	ENSG00000077080	0.23674517310698984	[439]	[267,315,NaN]	1	hSpCas9	negative selection	10091953
100656346	100656369	7	-	27869803	HPAFII	viability after 31 days	GCGCAGCGGGCACTATGAGCGGG	ACTL6B	ENSG00000077080	-4.79264713497913	[332]	[0,12,NaN]	-9	hSpCas9	negative selection	10091954
100655554	100655577	7	+	28162770	P31FUJ	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-3.9965678579243	[162]	[11]	-9	hSpCas9	negative selection	10106396
100655828	100655851	7	-	28162770	P31FUJ	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.04622596242190241	[267]	[304]	0	hSpCas9	negative selection	10106397
100655456	100655479	7	-	28162770	P31FUJ	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.3644462102248495	[171]	[156]	-3	hSpCas9	negative selection	10106398
100655020	100655043	7	+	28162770	P31FUJ	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	-0.6198253275236261	[169]	[129]	-5	hSpCas9	negative selection	10106399
100648765	100648788	7	-	28162770	P31FUJ	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	-0.261889783294894	[500]	[490]	-2	hSpCas9	negative selection	10106400
100648626	100648649	7	+	28162770	P31FUJ	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	-0.2124344067204168	[210]	[213]	-2	hSpCas9	negative selection	10106401
100647476	100647499	7	-	28162770	P31FUJ	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	-0.36822241366382436	[345]	[314]	-3	hSpCas9	negative selection	10106402
100646997	100647020	7	-	28162770	P31FUJ	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	-0.47560395732893357	[438]	[370]	-4	hSpCas9	negative selection	10106403
100646615	100646638	7	-	28162770	P31FUJ	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-2.8475120485295866	[48]	[7]	-9	hSpCas9	negative selection	10106404
100655871	100655894	7	-	28162770	P31FUJ	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	0.47641839926892326	[62]	[102]	5	hSpCas9	negative selection	10106405
100655554	100655577	7	+	28162770	TF1	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10275762
100655828	100655851	7	-	28162770	TF1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[187]	1	hSpCas9	negative selection	10275763
100655456	100655479	7	-	28162770	TF1	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10275764
100655020	100655043	7	+	28162770	TF1	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10275765
100648765	100648788	7	-	28162770	TF1	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10275766
100648626	100648649	7	+	28162770	TF1	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10275767
100647476	100647499	7	-	28162770	TF1	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10275768
100646997	100647020	7	-	28162770	TF1	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[564]	1	hSpCas9	negative selection	10275769
100646615	100646638	7	-	28162770	TF1	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10275770
100655871	100655894	7	-	28162770	TF1	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10275771
100655554	100655577	7	+	28162770	SKM1	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-1.2458094069285812	[54]	[40]	-7	hSpCas9	negative selection	10445128
100655828	100655851	7	-	28162770	SKM1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.6340630695168932	[38]	[106]	6	hSpCas9	negative selection	10445129
100655456	100655479	7	-	28162770	SKM1	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	0.43912311780315694	[62]	[150]	4	hSpCas9	negative selection	10445130
100655020	100655043	7	+	28162770	SKM1	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	-0.2973397075686634	[56]	[81]	-3	hSpCas9	negative selection	10445131
100648765	100648788	7	-	28162770	SKM1	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.5996385360810852	[108]	[291]	6	hSpCas9	negative selection	10445132
100648626	100648649	7	+	28162770	SKM1	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	-0.30979553973616336	[60]	[86]	-3	hSpCas9	negative selection	10445133
100647476	100647499	7	-	28162770	SKM1	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	-0.0075573511780822125	[57]	[101]	0	hSpCas9	negative selection	10445134
100646997	100647020	7	-	28162770	SKM1	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	-0.4199032544506598	[111]	[147]	-3	hSpCas9	negative selection	10445135
100646615	100646638	7	-	28162770	SKM1	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-1.2370391973008492	[3]	[2]	-7	hSpCas9	negative selection	10445136
100655871	100655894	7	-	28162770	SKM1	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	0.9731785100894964	[16]	[58]	8	hSpCas9	negative selection	10445137
100655554	100655577	7	+	28162770	SKM1	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-1.2458094069285812	[54]	[40]	-7	hSpCas9	negative selection	10614494
100655828	100655851	7	-	28162770	SKM1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.6340630695168932	[38]	[106]	6	hSpCas9	negative selection	10614495
100655456	100655479	7	-	28162770	SKM1	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	0.43912311780315694	[62]	[150]	4	hSpCas9	negative selection	10614496
100655020	100655043	7	+	28162770	SKM1	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	-0.2973397075686634	[56]	[81]	-3	hSpCas9	negative selection	10614497
100648765	100648788	7	-	28162770	SKM1	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.5996385360810852	[108]	[291]	6	hSpCas9	negative selection	10614498
100648626	100648649	7	+	28162770	SKM1	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	-0.30979553973616336	[60]	[86]	-3	hSpCas9	negative selection	10614499
100647476	100647499	7	-	28162770	SKM1	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	-0.0075573511780822125	[57]	[101]	0	hSpCas9	negative selection	10614500
100646997	100647020	7	-	28162770	SKM1	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	-0.4199032544506598	[111]	[147]	-3	hSpCas9	negative selection	10614501
100646615	100646638	7	-	28162770	SKM1	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-1.2370391973008492	[3]	[2]	-7	hSpCas9	negative selection	10614502
100655871	100655894	7	-	28162770	SKM1	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	0.9731785100894964	[16]	[58]	8	hSpCas9	negative selection	10614503
100655554	100655577	7	+	28162770	PL21	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	0.0882467344184229	[133]	[61]	0	hSpCas9	negative selection	10783860
100655828	100655851	7	-	28162770	PL21	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.5797282777638743	[205]	[133]	5	hSpCas9	negative selection	10783861
100655456	100655479	7	-	28162770	PL21	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.520337856888317	[289]	[87]	-4	hSpCas9	negative selection	10783862
100655020	100655043	7	+	28162770	PL21	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	-0.4794597603699114	[188]	[58]	-3	hSpCas9	negative selection	10783863
100648765	100648788	7	-	28162770	PL21	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.3143106344086315	[424]	[229]	2	hSpCas9	negative selection	10783864
100648626	100648649	7	+	28162770	PL21	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	0.5086886795754828	[259]	[160]	4	hSpCas9	negative selection	10783865
100647476	100647499	7	-	28162770	PL21	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.20013961448932013	[195]	[97]	1	hSpCas9	negative selection	10783866
100646997	100647020	7	-	28162770	PL21	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	-0.33037510220945954	[389]	[134]	-2	hSpCas9	negative selection	10783867
100646615	100646638	7	-	28162770	PL21	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	0.9860148091364727	[28]	[24]	8	hSpCas9	negative selection	10783868
100655871	100655894	7	-	28162770	PL21	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	-1.406517957331155	[66]	[10]	-7	hSpCas9	negative selection	10783869
100655554	100655577	7	+	28162770	P31FUJ	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-3.9965678579243	[162]	[11]	-9	hSpCas9	negative selection	10953226
100655828	100655851	7	-	28162770	P31FUJ	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.04622596242190241	[267]	[304]	0	hSpCas9	negative selection	10953227
100655456	100655479	7	-	28162770	P31FUJ	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.3644462102248495	[171]	[156]	-3	hSpCas9	negative selection	10953228
100655020	100655043	7	+	28162770	P31FUJ	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	-0.6198253275236261	[169]	[129]	-5	hSpCas9	negative selection	10953229
100648765	100648788	7	-	28162770	P31FUJ	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	-0.261889783294894	[500]	[490]	-2	hSpCas9	negative selection	10953230
100648626	100648649	7	+	28162770	P31FUJ	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	-0.2124344067204168	[210]	[213]	-2	hSpCas9	negative selection	10953231
100647476	100647499	7	-	28162770	P31FUJ	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	-0.36822241366382436	[345]	[314]	-3	hSpCas9	negative selection	10953232
100646997	100647020	7	-	28162770	P31FUJ	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	-0.47560395732893357	[438]	[370]	-4	hSpCas9	negative selection	10953233
100646615	100646638	7	-	28162770	P31FUJ	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-2.8475120485295866	[48]	[7]	-9	hSpCas9	negative selection	10953234
100655871	100655894	7	-	28162770	P31FUJ	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	0.47641839926892326	[62]	[102]	5	hSpCas9	negative selection	10953235
100655554	100655577	7	+	28162770	OCIAML5	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-1.2758742797705729	[54]	[40]	-6	hSpCas9	negative selection	11122592
100655828	100655851	7	-	28162770	OCIAML5	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.8805730978994191	[166]	[554]	7	hSpCas9	negative selection	11122593
100655456	100655479	7	-	28162770	OCIAML5	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.67590961571017	[153]	[173]	-4	hSpCas9	negative selection	11122594
100655020	100655043	7	+	28162770	OCIAML5	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.29934513292698833	[121]	[270]	2	hSpCas9	negative selection	11122595
100648765	100648788	7	-	28162770	OCIAML5	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.48415218157375917	[220]	[557]	4	hSpCas9	negative selection	11122596
100648626	100648649	7	+	28162770	OCIAML5	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	0.7715172238844668	[85]	[264]	6	hSpCas9	negative selection	11122597
100647476	100647499	7	-	28162770	OCIAML5	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.08011804490843144	[195]	[373]	0	hSpCas9	negative selection	11122598
100646997	100647020	7	-	28162770	OCIAML5	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.33134165994193765	[283]	[644]	3	hSpCas9	negative selection	11122599
100646615	100646638	7	-	28162770	OCIAML5	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	1.936429323942291	[10]	[75]	9	hSpCas9	negative selection	11122600
100655871	100655894	7	-	28162770	OCIAML5	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	-0.9191807667225338	[65]	[62]	-5	hSpCas9	negative selection	11122601
100655554	100655577	7	+	28162770	EOL1	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.4665638884628289	[298]	[113]	-3	hSpCas9	negative selection	11291958
100655828	100655851	7	-	28162770	EOL1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.6551780807844745	[274]	[91]	-5	hSpCas9	negative selection	11291959
100655456	100655479	7	-	28162770	EOL1	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.2001031501073372	[446]	[204]	-1	hSpCas9	negative selection	11291960
100655020	100655043	7	+	28162770	EOL1	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	-0.3058819688313317	[419]	[178]	-2	hSpCas9	negative selection	11291961
100648765	100648788	7	-	28162770	EOL1	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.21529997057471917	[841]	[514]	2	hSpCas9	negative selection	11291962
100648626	100648649	7	+	28162770	EOL1	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	0.9245477715705346	[383]	[383]	7	hSpCas9	negative selection	11291963
100647476	100647499	7	-	28162770	EOL1	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	-0.38827811620957536	[394]	[158]	-3	hSpCas9	negative selection	11291964
100646997	100647020	7	-	28162770	EOL1	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.5549930420856992	[561]	[434]	5	hSpCas9	negative selection	11291965
100646615	100646638	7	-	28162770	EOL1	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-1.0754522284294654	[43]	[10]	-6	hSpCas9	negative selection	11291966
100655871	100655894	7	-	28162770	EOL1	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	0.67300900457457	[99]	[83]	6	hSpCas9	negative selection	11291967
100655554	100655577	7	+	28162770	MOLM13	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.7968138446498336	[172]	[71]	-4	hSpCas9	negative selection	11461324
100655828	100655851	7	-	28162770	MOLM13	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.49930233417604036	[317]	[324]	4	hSpCas9	negative selection	11461325
100655456	100655479	7	-	28162770	MOLM13	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	0.2679518110358268	[339]	[295]	2	hSpCas9	negative selection	11461326
100655020	100655043	7	+	28162770	MOLM13	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.5198414611793005	[299]	[310]	4	hSpCas9	negative selection	11461327
100648765	100648788	7	-	28162770	MOLM13	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.8483282192994561	[632]	[823]	6	hSpCas9	negative selection	11461328
100648626	100648649	7	+	28162770	MOLM13	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	0.31645663601796287	[280]	[252]	2	hSpCas9	negative selection	11461329
100647476	100647499	7	-	28162770	MOLM13	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.396336120519545	[371]	[353]	3	hSpCas9	negative selection	11461330
100646997	100647020	7	-	28162770	MOLM13	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	-0.15851783747392856	[564]	[365]	-1	hSpCas9	negative selection	11461331
100646615	100646638	7	-	28162770	MOLM13	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-1.0175374456256634	[41]	[14]	-5	hSpCas9	negative selection	11461332
100655871	100655894	7	-	28162770	MOLM13	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	1.7427492227751622	[80]	[195]	9	hSpCas9	negative selection	11461333
100655554	100655577	7	+	28162770	HEL	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.11743415332717433	[187]	[110]	-1	hSpCas9	negative selection	11630690
100655828	100655851	7	-	28162770	HEL	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.3906202036457468	[236]	[198]	3	hSpCas9	negative selection	11630691
100655456	100655479	7	-	28162770	HEL	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	0.5965686505674309	[253]	[245]	5	hSpCas9	negative selection	11630692
100655020	100655043	7	+	28162770	HEL	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.36263091280762166	[288]	[237]	3	hSpCas9	negative selection	11630693
100648765	100648788	7	-	28162770	HEL	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.5318116815582223	[553]	[512]	4	hSpCas9	negative selection	11630694
100648626	100648649	7	+	28162770	HEL	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	0.32822820867547753	[290]	[233]	2	hSpCas9	negative selection	11630695
100647476	100647499	7	-	28162770	HEL	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.705702789664659	[268]	[280]	6	hSpCas9	negative selection	11630696
100646997	100647020	7	-	28162770	HEL	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	-0.3638338219231293	[439]	[218]	-3	hSpCas9	negative selection	11630697
100646615	100646638	7	-	28162770	HEL	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-2.164616090057247	[20]	[2]	-8	hSpCas9	negative selection	11630698
100655871	100655894	7	-	28162770	HEL	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	0.4095396557073261	[66]	[56]	3	hSpCas9	negative selection	11630699
100655554	100655577	7	+	28162770	MV411	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.9564347825828748	[128]	[55]	-6	hSpCas9	negative selection	11800056
100655828	100655851	7	-	28162770	MV411	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.6194063281697331	[152]	[197]	5	hSpCas9	negative selection	11800057
100655456	100655479	7	-	28162770	MV411	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	0.5090651354023235	[170]	[204]	4	hSpCas9	negative selection	11800058
100655020	100655043	7	+	28162770	MV411	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.20258331499851487	[195]	[189]	1	hSpCas9	negative selection	11800059
100648765	100648788	7	-	28162770	MV411	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.40138891601734694	[443]	[493]	3	hSpCas9	negative selection	11800060
100648626	100648649	7	+	28162770	MV411	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	0.14826214569193985	[285]	[266]	1	hSpCas9	negative selection	11800061
100647476	100647499	7	-	28162770	MV411	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	-0.49496192943405876	[265]	[158]	-4	hSpCas9	negative selection	11800062
100646997	100647020	7	-	28162770	MV411	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	-0.14849112554836386	[399]	[303]	-1	hSpCas9	negative selection	11800063
100646615	100646638	7	-	28162770	MV411	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	0.14052234686626353	[13]	[12]	1	hSpCas9	negative selection	11800064
100655871	100655894	7	-	28162770	MV411	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	-0.5339221627418842	[54]	[31]	-4	hSpCas9	negative selection	11800065
100655554	100655577	7	+	28162770	MONOMAC1	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	0.05777705196927163	[87]	[104]	0	hSpCas9	negative selection	11969422
100655828	100655851	7	-	28162770	MONOMAC1	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.4205918425819247	[130]	[200]	4	hSpCas9	negative selection	11969423
100655456	100655479	7	-	28162770	MONOMAC1	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.043124163605872234	[150]	[167]	0	hSpCas9	negative selection	11969424
100655020	100655043	7	+	28162770	MONOMAC1	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	-0.056438516886753026	[126]	[139]	0	hSpCas9	negative selection	11969425
100648765	100648788	7	-	28162770	MONOMAC1	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.7882865763080023	[246]	[488]	7	hSpCas9	negative selection	11969426
100648626	100648649	7	+	28162770	MONOMAC1	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	-0.2824283382901983	[173]	[163]	-3	hSpCas9	negative selection	11969427
100647476	100647499	7	-	28162770	MONOMAC1	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.6278764463823552	[139]	[247]	6	hSpCas9	negative selection	11969428
100646997	100647020	7	-	28162770	MONOMAC1	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.6607535297099569	[260]	[472]	6	hSpCas9	negative selection	11969429
100646615	100646638	7	-	28162770	MONOMAC1	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-1.9625715934225307	[16]	[4]	-8	hSpCas9	negative selection	11969430
100655871	100655894	7	-	28162770	MONOMAC1	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	-0.4449643605031395	[37]	[31]	-4	hSpCas9	negative selection	11969431
100655554	100655577	7	+	28162770	OCIAML2	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	-0.8242667798568616	[22]	[71]	-5	hSpCas9	negative selection	12138788
100655828	100655851	7	-	28162770	OCIAML2	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	-0.1300056366448939	[45]	[232]	-1	hSpCas9	negative selection	12138789
100655456	100655479	7	-	28162770	OCIAML2	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	-0.5230972451362967	[55]	[215]	-4	hSpCas9	negative selection	12138790
100655020	100655043	7	+	28162770	OCIAML2	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.20056507312307376	[45]	[292]	2	hSpCas9	negative selection	12138791
100648765	100648788	7	-	28162770	OCIAML2	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	0.5629527752822195	[68]	[564]	5	hSpCas9	negative selection	12138792
100648626	100648649	7	+	28162770	OCIAML2	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	0.07883399425760862	[47]	[280]	0	hSpCas9	negative selection	12138793
100647476	100647499	7	-	28162770	OCIAML2	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	0.6737600840930137	[37]	[335]	6	hSpCas9	negative selection	12138794
100646997	100647020	7	-	28162770	OCIAML2	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.25729062932103797	[55]	[370]	2	hSpCas9	negative selection	12138795
100646615	100646638	7	-	28162770	OCIAML2	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	2.6448473921777746	[5]	[207]	9	hSpCas9	negative selection	12138796
100655871	100655894	7	-	28162770	OCIAML2	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	0.2663357689240451	[5]	[39]	2	hSpCas9	negative selection	12138797
100655554	100655577	7	+	28162770	OCIAML3	viability	GGCCAGCAGCCCCACTGTGGTGG	ACTL6B	ENSG00000077080	0.5540909986649708	[36]	[163]	5	hSpCas9	negative selection	12308154
100655828	100655851	7	-	28162770	OCIAML3	viability	GGCTCCTTCTCAGTCCGCGCTGG	ACTL6B	ENSG00000077080	0.213347281733441	[59]	[209]	2	hSpCas9	negative selection	12308155
100655456	100655479	7	-	28162770	OCIAML3	viability	GCCCTGCACGTGCCTCGGGATGG	ACTL6B	ENSG00000077080	1.2225462185799056	[66]	[471]	8	hSpCas9	negative selection	12308156
100655020	100655043	7	+	28162770	OCIAML3	viability	GGAGCCTCGGACATGAGCACTGG	ACTL6B	ENSG00000077080	0.2378696008675099	[49]	[177]	2	hSpCas9	negative selection	12308157
100648765	100648788	7	-	28162770	OCIAML3	viability	CAGTGGAGCCACCCACACCACGG	ACTL6B	ENSG00000077080	1.031369128842901	[87]	[542]	8	hSpCas9	negative selection	12308158
100648626	100648649	7	+	28162770	OCIAML3	viability	GAGATGAAGTCCCCTGCCAGAGG	ACTL6B	ENSG00000077080	0.3577371910686158	[75]	[293]	3	hSpCas9	negative selection	12308159
100647476	100647499	7	-	28162770	OCIAML3	viability	GAAGAAGGAGAAGCTACCCCAGG	ACTL6B	ENSG00000077080	-0.20698451721491587	[64]	[169]	-2	hSpCas9	negative selection	12308160
100646997	100647020	7	-	28162770	OCIAML3	viability	CGAGCGACTCCGCATCCCTGAGG	ACTL6B	ENSG00000077080	0.3349092616143544	[77]	[296]	3	hSpCas9	negative selection	12308161
100646615	100646638	7	-	28162770	OCIAML3	viability	GGGAGTGTCATTGTCACCGGCGG	ACTL6B	ENSG00000077080	-0.9565777197088714	[8]	[13]	-6	hSpCas9	negative selection	12308162
100655871	100655894	7	-	28162770	OCIAML3	viability	GTCTCCCCGCACAGATGAGGTGG	ACTL6B	ENSG00000077080	0.6665199098990557	[23]	[114]	6	hSpCas9	negative selection	12308163